Rho
Rho inhibitors target the Rho family of GTPases, which are critical regulators of the cytoskeleton, cell division, and signal transduction pathways. Rho GTPases are involved in controlling the dynamics of actin filaments, cell shape, and motility, as well as progression through the cell cycle. Dysregulation of Rho signaling can lead to uncontrolled cell proliferation and cancer. Inhibiting Rho GTPases can induce cell cycle arrest and apoptosis, making these inhibitors valuable tools in cancer research and the study of cell motility. At CymitQuimica, we offer a range of high-quality Rho inhibitors to support your research in cell cycle regulation, cytoskeletal dynamics, and oncology.
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(E/Z)-ZINC09659342
CAS:591726-26-0
(E/Z)-ZINC09659342 is an inhibitor of Lbc-Rho A interaction.
Formula:
C23H15F3N2O4
Purity:
95.83%
Color and Shape:
Liquid
Molecular weight:
440.37
Ref: TM-T9986
| 1mg | 64.00 € | ||
| 5mg | 141.00 € | ||
| 10mg | 214.00 € | ||
| 25mg | 365.00 € | ||
| 50mg | 516.00 € | ||
| 100mg | 694.00 € | ||
| 200mg | 906.00 € | ||
| 1mL*10mM (DMSO) | 155.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Z62954982
CAS:1090893-12-1
Z62954982 (ZINC08010136) is a Rac1 inhibitor that inhibits Rac1 activation and reduces proliferation, p38 phosphorylation, …
Formula:
C20H21N3O5S
Purity:
98.28%
Color and Shape:
Solid
Molecular weight:
415.46
Ref: TM-T37113
| 1mg | 38.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 183.00 € | ||
| 50mg | 263.00 € | ||
| 100mg | 384.00 € | ||
| 500mg | 871.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Y16
CAS:429653-73-6
Y16 is a G protein-coupled Rho GEFs inhibitor and also a specific inhibitor of LARG …
Formula:
C24H20N2O3
Purity:
98.26% - 99.32%
Color and Shape:
Solid
Molecular weight:
384.43
Ref: TM-T3553
| 1mg | 35.00 € | ||
| 2mg | 50.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 114.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 274.00 € | ||
| 100mg | 407.00 € | ||
| 1mL*10mM (DMSO) | 81.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
CCG-203971
CAS:1443437-74-8
CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: …
Formula:
C23H21ClN2O3
Purity:
98.82% - 99.35%
Color and Shape:
Solid
Molecular weight:
408.88
Ref: TM-T4306
| 10mg | 53.00 € | ||
| 25mg | 94.00 € | ||
| 50mg | 144.00 € | ||
| 100mg | 224.00 € | ||
| 500mg | 553.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
EHT 1864
CAS:754240-09-0
EHT 1864 (EHT 1864 2HCl) is a Rac family GTPase inhibitor that blocks activation by …
Formula:
C25H29Cl2F3N2O4S
Purity:
98.39% - 99.42%
Color and Shape:
Solid
Molecular weight:
581.47
Ref: TM-T6483
| 1mg | 46.00 € | ||
| 5mg | 90.00 € | ||
| 10mg | 134.00 € | ||
| 25mg | 254.00 € | ||
| 50mg | 464.00 € | ||
| 100mg | 666.00 € | ||
| 200mg | 917.00 € | ||
| 1mL*10mM (DMSO) | 107.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
EHop-016
CAS:1380432-32-5
EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in …
Formula:
C25H30N6O
Purity:
100% - 99.86%
Color and Shape:
Solid
Molecular weight:
430.55
Ref: TM-T2427
| 5mg | 47.00 € | ||
| 10mg | 72.00 € | ||
| 25mg | 124.00 € | ||
| 50mg | 209.00 € | ||
| 100mg | 327.00 € | ||
| 200mg | 483.00 € | ||
| 500mg | 770.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
1A-116
CAS:1430208-73-3
1A-116 is a specific Rac1 inhibitor.
Formula:
C16H16F3N3
Purity:
98.43%
Color and Shape:
Solid
Molecular weight:
307.31
Ref: TM-T14004
| 1mg | 50.00 € | ||
| 5mg | 110.00 € | ||
| 10mg | 178.00 € | ||
| 25mg | 355.00 € | ||
| 50mg | 533.00 € | ||
| 100mg | 765.00 € | ||
| 500mg | 1,566.00 € | ||
| 1mL*10mM (DMSO) | 122.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
MLS000532223
CAS:16616-39-0
MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM).
Formula:
C15H9NO3
Purity:
98.60%
Color and Shape:
Solid
Molecular weight:
251.24
Ref: TM-T8473
| 1mg | 129.00 € | ||
| 2mg | 180.00 € | ||
| 5mg | 303.00 € | ||
| 10mg | 456.00 € | ||
| 25mg | 746.00 € | ||
| 50mg | 1,023.00 € | ||
| 100mg | 1,398.00 € | ||
| 1mL*10mM (DMSO) | 315.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
CCG-222740
CAS:1922098-69-8
CCG-222740 is an inhibitor of Rho/MRTF pathway
Formula:
C23H19ClF2N2O3
Purity:
98.76%
Color and Shape:
Solid
Molecular weight:
444.86
Ref: TM-T7764
| 2mg | 41.00 € | ||
| 5mg | 63.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 177.00 € | ||
| 50mg | 271.00 € | ||
| 100mg | 402.00 € | ||
| 200mg | 570.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
CCG-100602
CAS:1207113-88-9
CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).
Formula:
C21H17ClF6N2O2
Purity:
99.58%
Color and Shape:
Solid
Molecular weight:
478.82
Ref: TM-T22062
| 5mg | 38.00 € | ||
| 10mg | 56.00 € | ||
| 25mg | 113.00 € | ||
| 50mg | 185.00 € | ||
| 100mg | 298.00 € | ||
| 200mg | 442.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Digeranyl bisphosphonate
CAS:878143-03-4
Digeranyl bisphosphonate (DGBP) is a potent geranylgeranyl pyrophosphate (GGPP) synthase inhibitor that inhibits geranyl pyrophosphorylation …
Formula:
C21H34Na4O6P2
Purity:
98.5%
Color and Shape:
Solid
Molecular weight:
536.4
Ref: TM-T12452
| 1mg | 248.00 € | ||
| 5mg | 499.00 € | ||
| 10mg | 800.00 € | ||
| 25mg | 1,410.00 € | ||
| 50mg | 1,846.00 € | ||
| 100mg | 2,322.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
Rhosin
CAS:1173671-63-0
Rhosin is a specific inhibitor of RhoA GTPases (Kd: ~0.4 uM), blocking RhoA-GEF interaction, not …
Formula:
C20H18N6O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
358.4
Ref: TM-T16746
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
CCG-257081
CAS:1922098-90-5
CCG-257081 blocks Rho/MRTF/SRF pathway; prevents fibrosis in mice; useful in cancer and fibrosis research.
Formula:
C24H19ClF3N3O2
Purity:
98% - 99.92%
Color and Shape:
Solid
Molecular weight:
473.87
Ref: TM-T30778
| 1mg | 125.00 € | ||
| 5mg | 293.00 € | ||
| 10mg | 435.00 € | ||
| 25mg | 714.00 € | ||
| 50mg | 1,000.00 € | ||
| 100mg | 1,346.00 € | ||
| 500mg | 2,685.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
ML-099
CAS:496775-95-2
ML-099 is a pan Ras-related GTPases activator that activates Rac1, Ras, GTP-binding protein (Rab7), Rab2A …
Formula:
C14H13NO2S
Purity:
99.48%
Color and Shape:
Solid
Molecular weight:
259.32
Ref: TM-T22991
| 1mg | 48.00 € | ||
| 2mg | 63.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 149.00 € | ||
| 25mg | 300.00 € | ||
| 50mg | 476.00 € | ||
| 100mg | 694.00 € | ||
| 1mL*10mM (DMSO) | 93.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
