Dynamin
Dynamin inhibitors target dynamin, a GTPase enzyme that plays a crucial role in endocytosis, vesicle trafficking, and cytokinesis. Dynamin is involved in the scission of vesicles from membranes and is essential for the proper distribution of cellular components during cell division. Inhibiting dynamin can disrupt these processes, leading to defects in cell division and inducing cell cycle arrest. Dynamin inhibitors are valuable in studying endocytosis, cell division, and membrane dynamics. At CymitQuimica, we provide a range of high-quality dynamin inhibitors to support your research in cell biology, membrane trafficking, and cell cycle regulation.
Found 23 products of "Dynamin"
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DynaMin inhibitory peptide, myristoylated
CAS:<p>Cell-permeable dynamin inhibitor; blocks its binding to amphiphysin, hindering endocytosis; curbs NMDA receptor internalization.</p>Formula:C61H107N19O14Purity:98%Color and Shape:SolidMolecular weight:1330.64TAT-P110
CAS:<p>TAT-P110 is a peptide inhibitor that disrupts the interaction between Drp1 and Fis1, effectively reducing pathological changes in various models of neurodegenerative diseases, ischemia, and sepsis without impairing the physiological function of Drp1.</p>Formula:C100H178N44O26Molecular weight:2412.76Dynamin inhibitory peptide TFA
<p>Dynamin inhibitory peptide TFA hinders dynamin-amphiphysin interaction and endocytosis, affecting dopamine D3 and GABA A receptors.</p>Formula:C49H81F3N18O16Color and Shape:SolidMolecular weight:1235.27Drp1 peptide inhibitor P110
CAS:<p>Compound P110 (Drp1 peptide inhibitor P110) is a selective Drp1 peptide inhibitor with neuroprotective effects. It inhibits the activation of Drp1, prevents Drp1 mitochondrial translocation induced by MPTP, and alleviates dopamine neuron loss, dopaminergic terminal damage, and behavioral deficits caused by MPTP. This compound is useful for Alzheimer's disease research. Additionally, Compound P110 reduces mitochondrial and organ damage in animal models of Huntington's disease, cerebral ischemia, and myocardial infarction.</p>Formula:C100H179N45O25Color and Shape:SolidMolecular weight:2411.78IIQLPEIVVV TFA
<p>IIQLPEIVVV TFA serves as a specific inhibitor targeting the Drp1-Mff interaction. This compound discriminates between physiological and pathological fission, hindering physiological fission which leads to mitochondrial dysfunction. IIQLPEIVVV TFA is also utilized in research related to Huntington's disease.</p>Formula:C54H95N11O14·xC2HF3O2Color and Shape:SolidMolecular weight:1122.40 (free base)Dynamin IN-2
CAS:<p>Dynamin IN-2 (compound 43) is a Wiskostatin analogue.</p>Formula:C22H21ClN2OPurity:99.36% - 99.37%Color and Shape:SoildMolecular weight:364.87Anti-Clathrin Heavy Chain Antibody
<p>Anti-Clathrin Heavy Chain Antibody is a human-source antibody expressed in CHO cells, specifically targeting the Clathrin Heavy Chain. For isotype control, please refer to Human IgG1 kappa, Isotype Control.</p>Color and Shape:Odour LiquidSchaftoside
CAS:<p>Schaftoside (APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE) has antioxidant and anticancer activity.</p>Formula:C26H28O14Purity:98% - >99.99%Color and Shape:SolidMolecular weight:564.49Mdivi-1
CAS:<p>Mdivi-1 (Mitochondrial division inhibitor 1) is a mitochondrial division inhibitor that inhibits DRP1 and Dynamin I (IC50=1-10 μM).</p>Formula:C15H10Cl2N2O2SPurity:96.57% - 99.23%Color and Shape:SolidMolecular weight:353.22Dynasore
CAS:<p>Dynasore, a cell-permeable dynamin inhibitor, blocks GTPase of dynamin 1/2 and Drp1 (IC50: 15 μM) without affecting other small GTPases.</p>Formula:C18H14N2O4Purity:95.85% - 99.22%Color and Shape:SolidMolecular weight:322.31Tetradecyltrimethylammonium bromide
CAS:<p>Tetradecyltrimethylammonium bromide (MitMAB) is a Dynamin GTPase activity inhibitor and a cationic surfactant with asymmetrical structure.</p>Formula:C17H38BrNPurity:99.80%Color and Shape:SolidMolecular weight:336.39Trimethyloctadecylammonium bromide
CAS:<p>Trimethyloctadecylammonium bromide is an inhibitor of Dynamin I(IC50 : 1.9 μM) and also inhibits Dynamin Ⅱ.</p>Formula:C21H46N·BrPurity:99.09%Color and Shape:Solid SolidMolecular weight:392.5Hydroxy-Dynasore
CAS:<p>Hydroxy-Dynasore (Dyngo-4a) , a effective dynamin inhibitor, inhibits withDynI (brain), DynI (rec), and DynII (rec) of IC50 of 0.38 μM, 1.1 μM, and 2.3 μM,</p>Formula:C18H14N2O5Purity:97.60% - >99.99%Color and Shape:SolidMolecular weight:338.31DNM1 Protein, Human, Recombinant (His)
<p>Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP.</p>Color and Shape:Lyophilized PowderMolecular weight:32.2 kDa (predicted)Clathrin-IN-25
CAS:<p>Clathrin-IN-25 is the most effective clathrin terminal domain-amphiphysin inhibitor reported to date.</p>Formula:C19H13KNO5SColor and Shape:SolidMolecular weight:406.47Dynamin IN-1
CAS:<p>Dynamin IN-1 is a potent dynamin inhibitor with an IC 50 value of 1.0 µM .</p>Formula:C23H24N2OColor and Shape:SolidMolecular weight:344.45DRP1i27
CAS:<p>DRP1i27 inhibits human Drp1 at GTPase site, prevents mitochondrial fission, and shields cells from ischemia-reperfusion damage.</p>Formula:C20H26N6OColor and Shape:SolidMolecular weight:366.46Clathrin-IN-2
CAS:<p>Clathrin-IN-2: CME inhibitor, IC50 - 2.3μM; also blocks dyn I GTPase, IC50 - 7.7μM.</p>Formula:C17H18Br2N2OColor and Shape:SolidMolecular weight:426.15Ellipticine quinone
CAS:<p>Ellipticine quinone (NSC-383230) outperforms mdivi-1 in inhibiting Drp1, reduces lung cancer growth, and lessens IR injury by curbing mitochondrial issues.</p>Formula:C15H8N2O2Color and Shape:SolidMolecular weight:248.24Drp1-IN-1
CAS:<p>Drp1-IN-1 (comp A-7) is a Drp1 protein inhibitor (IC50: 0.91 μM).</p>Formula:C22H24N8OSColor and Shape:SolidMolecular weight:448.54
