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Chromatin/Epigenetics

Chromatin/Epigenetics

Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.

Subcategories of "Chromatin/Epigenetics"

Found 2235 products of "Chromatin/Epigenetics"

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  • Dimethyl-bisphenol A

    CAS:
    <p>DMBPA inhibits HIF-1α, promotes its degradation by detaching Hsp90, and reduces Vegfa mRNA expression.</p>
    Formula:C17H20O2
    Color and Shape:Solid
    Molecular weight:256.34
  • TyK2-IN-2

    CAS:
    <p>TyK2-IN-2 is a selective inhibitor of TYK2 (IC50s: 7 nM, 0.1 μM, and 0.05 μM for TYK2 JH2, IL-23, and IFNα).</p>
    Formula:C16H18N6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:310.35
  • SRI-42127

    CAS:
    <p>SRI-42127 is a novel small molecule inhibitor of the RNA regulatory factor HuR that inhibits tumor growth and reduces neuropathic pain following nerve injury.</p>
    Formula:C19H20N6O
    Purity:99.66%
    Color and Shape:Solid
    Molecular weight:348.4
  • SIRT5 inhibitor 6

    CAS:
    <p>SIRT5 inhibitor 6 is Sirtuin 5 inhibitor for sepsis-associated acute kidney injury (AKI) modulates protein succinylation and pro-inflammatory cytokine release.</p>
    Formula:C21H28N6O4S
    Purity:99.84%
    Color and Shape:Solid
    Molecular weight:460.55
  • CTX-0124143

    CAS:
    <p>CTX-0124143 is a histone acetyltransferase inhibitor with an IC50 value of 1.0 μM for KAT6A.CTX-0124143 can be used to study cellular senescence.</p>
    Formula:C17H13FN2O3S
    Purity:99.16%
    Color and Shape:Solid
    Molecular weight:344.36
  • NSD3-IN-2

    CAS:
    <p>NSD3-IN-2: Potent NSD3 inhibitor, IC50 17.97μM, halts NSCLC growth (H460, H1299, H1650) with anticancer effects.</p>
    Formula:C17H15N5OS
    Color and Shape:Solid
    Molecular weight:337.4
  • NSD3-IN-3

    CAS:
    <p>"NSD3-IN-3, a potent anticancer agent, inhibits NSD3 (IC50: 1.86 μM) and hampers H460 lung cancer cell growth."</p>
    Formula:C15H17N5O2S
    Color and Shape:Solid
    Molecular weight:331.39
  • PRMT5-IN-C17

    CAS:
    <p>PRMT5-IN-C17 is a novel potent, selective, and cell active protein arginine methyltransferase 5 (PRMT5) inhibitor.</p>
    Formula:C18H17N3O4S
    Color and Shape:Solid
    Molecular weight:371.41
  • 5WKS

    CAS:
    <p>5WKS, or ZINC97756584, is a G9a inhibitor targeting H3K9me2 for gene silencing research in autoimmune diseases and tumors.</p>
    Formula:C24H36ClN5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:462.03
  • NC-III-49-1

    CAS:
    <p>NC-III-49-1: potent BET inhibitor, binds BRD4/BRDT, inhibits cell growth, reduces c-Myc expression.</p>
    Formula:C44H50N4O11S2
    Color and Shape:Soild
    Molecular weight:875.02
  • CL67

    CAS:
    <p>CL67 is a hypoxia-inducible factor pathway inhibitor. It acts by binding to a G-quadruplex higher-order structure in the HIF promoter sequence in vitro.</p>
    Formula:C38H42N10O2
    Color and Shape:Solid
    Molecular weight:670.81
  • HDAC-IN-44

    CAS:
    <p>HDAC-IN-44 is an HDAC inhibitor (IC50: 61.2 nM) with strong anti-cancer effects.</p>
    Formula:C26H27BrN4O4
    Color and Shape:Solid
    Molecular weight:539.42
  • PDAT

    CAS:
    <p>PDAT is a noncompetitive Indolethylamine N-methyltransferase inhibitor.</p>
    Formula:C15H23N3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:245.36
  • TM6008

    CAS:
    <p>TM6008 is an inhibitor of prolyl hydroxylase that protects against cell death after hypoxia.</p>
    Formula:C21H17N5O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:387.39
  • BET bromodomain inhibitor 2

    CAS:
    <p>BET bromodomain inhibitor 2 is a potent inhibitor of the BET-type bromodomain (IC50: 14.1 μM).</p>
    Formula:C23H30N2O5S
    Color and Shape:Solid
    Molecular weight:446.56
  • SKF 91488 dihydrochloride

    CAS:
    <p>histamine N-methyltransferase inhibitor</p>
    Formula:C7H19Cl2N3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:248.22
  • GDC-4379

    CAS:
    <p>GDC-4379 is a JAK1 inhibitor that can be used to study asthma.</p>
    Formula:C21H18ClF2N7O3
    Color and Shape:Solid
    Molecular weight:489.86
  • Y08175

    CAS:
    <p>Y08175, a CBP Bromodomain inhibitor, IC50: 37 nM (AlphaScreen), 178.15 nM (HTRF). Useful in prostate cancer research.</p>
    Formula:C23H19FN4O5
    Color and Shape:Solid
    Molecular weight:450.42
  • RSC-133

    CAS:
    <p>promotes the reprogramming of human somatic cells to pluripotent stem cells</p>
    Formula:C18H15N3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:305.33
  • HDAC6-IN-10

    CAS:
    <p>HDAC6-IN-10 is a potent HDAC6 inhibitor with 0.73 nM IC50, highly selective, and hinders multiple myeloma cell growth.</p>
    Formula:C21H20N4O4
    Color and Shape:Solid
    Molecular weight:392.41
  • MAT2A inhibitor 3

    CAS:
    <p>MAT2A inhibitor 3 can be used in the cancer research.</p>
    Formula:C16H14ClN3O
    Color and Shape:Solid
    Molecular weight:299.75
  • MAT2A-IN-5

    CAS:
    <p>MAT2A-IN-5 inhibits MAT2A in tumors, curbing growth in gastric, colon, liver, and pancreatic cancers.</p>
    Formula:C17H12ClF3N2O
    Color and Shape:Solid
    Molecular weight:352.74
  • SIRT6-IN-1

    CAS:
    <p>SIRT6-IN-1, a novel SIRT6 inhibitor, reduces glycemia and improves oral glucose tolerance in unfed wild-type mice.</p>
    Formula:C19H14N4O5S
    Color and Shape:Solid
    Molecular weight:410.4
  • JAK3i

    CAS:
    <p>JAK3i selectively inhibits JAK3 kinase, targeting the second, vital wave of STAT5 phosphorylation for T cell growth.</p>
    Formula:C18H15FN4O3
    Purity:98.61% - 99.81%
    Color and Shape:Solid
    Molecular weight:354.34
  • ABT-472

    CAS:
    <p>ABT-472 is a novel PARP inhibitor</p>
    Formula:C20H28N4O5
    Color and Shape:Solid
    Molecular weight:404.46
  • INCB054329 Racemate

    CAS:
    <p>INCB054329 Racemate is an inhibitor of BET protein.</p>
    Formula:C19H16N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:348.36
  • EML741

    CAS:
    <p>EML741 also inhibits DNMT1 (IC50, 3.1 μM), with no effect on DNMT3a or DNMT3b.</p>
    Formula:C31H49N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:523.75
  • IHCH-3064

    CAS:
    <p>IHCH-3064: dual-action cancer immunotherapy, A2AR affinity (Ki 2.2 nM), selective HDAC1 inhibitor (IC50 80.2 nM).</p>
    Formula:C25H21N9O2
    Color and Shape:Solid
    Molecular weight:479.49
  • HDAC6-IN-6

    CAS:
    <p>HDAC6-IN-6: Potent HDAC6 blocker, BBB-permeable, IC50: 0.025μM; inhibits AChE, Aβ 1-42 aggregation; promotes neurite growth, low neurotoxicity.</p>
    Formula:C20H15N3O2
    Color and Shape:Solid
    Molecular weight:329.35
  • A2AAR/HDAC-IN-2

    CAS:
    <p>A2AAR/HDAC-IN-2: potent dual A2AAR/HDAC inhib., Ki 10.3 nM, IC50 18.5 nM, anti-tumor potential.</p>
    Formula:C23H26N6O4
    Color and Shape:Solid
    Molecular weight:450.49
  • NSC 698600

    CAS:
    <p>NSC 698600 is a potent inhibitor of PCAF(p300/CBP-associated factor) with IC 50 of 6.51 μM that shows good inhibition activity of cancer cell proliferation [1].</p>
    Formula:C14H12N2O2S
    Color and Shape:Solid
    Molecular weight:272.32
  • SPC-180002

    CAS:
    <p>SPC-180002, a dual SIRT1/3 inhibitor, exhibits IC50 values of 1.13 and 5.41 μM for SIRT1 and SIRT3, respectively.</p>
    Formula:C18H23NO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:317.38
  • JAK-IN-18

    CAS:
    <p>"JAK-IN-18: potent JAK inhibitor for eye, skin, respiratory disease research (WO2018204238A1, comp 1)."</p>
    Formula:C27H28F2N6O3
    Color and Shape:Solid
    Molecular weight:522.55
  • Setin-1

    CAS:
    <p>Setin-1 is the most potent Set7 inhibitor that acts by inhibiting the KMTase G9a.</p>
    Formula:C29H21F3N2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:486.48
  • GSK 525768A

    CAS:
    <p>GSK 525768A, the inactive enantiomer of GSK525762A, exhibits no activity towards BET.</p>
    Formula:C22H22ClN5O2
    Color and Shape:Solid
    Molecular weight:423.9
  • OXFBD03

    CAS:
    <p>OXFBD03 is the bromodomain and extra terminal domain bromodomain family member BRD4(1) inhibitor.</p>
    Formula:C20H19NO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:337.37
  • LY 170198

    CAS:
    <p>LY 170198 is a protein kinase C inhibitor.</p>
    Formula:C22H25N5O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:439.46
  • HPCG

    CAS:
    <p>HPCG is an inhibitor of HIF-1α prolyl hydroxylase.</p>
    Formula:C8H8N2O4
    Color and Shape:Solid
    Molecular weight:196.16
  • DHPCC-9

    CAS:
    <p>DHPCC-9 is an inhibitor of Pim kinase.</p>
    Formula:C15H10N2O
    Color and Shape:Solid
    Molecular weight:234.25
  • DC_501

    CAS:
    <p>DC_501 is a selective non-nucleoside DNA methyltransferase 1 inhibitor.</p>
    Formula:C25H23Cl2N3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:452.38
  • Sirtuin modulator 4

    CAS:
    <p>Sirtuin modulator 4 inhibits SIRT1 (EC50: 51-100 μM), may extend cell life and prevent diseases like diabetes and cancer.</p>
    Formula:C18H10N2O2S
    Color and Shape:Solid
    Molecular weight:318.35
  • DCE_254

    CAS:
    <p>DCE_254 is a novel EZH2 inhibitor, it also displays significant anti-proliferation activity against lymphoma cell lines.</p>
    Formula:C21H17N9OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:443.48
  • Langkamide

    CAS:
    <p>Langkamide is a HIF-2 inhibitor with EC₅₀ values of 14.0 uM.</p>
    Formula:C16H17NO5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:303.31
  • I-BET151 dihydrochloride

    CAS:
    <p>I-BET 151 dihydrochloride is a BET bromodomain inhibitor that prevents BET from recruiting to chromatin.</p>
    Formula:C23H23Cl2N5O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:488.37
  • Vibsanin A

    CAS:
    <p>Vibsanin A, an activator of protein kinase C (PKC) and an inhibitor of HSP90, demonstrates anti-proliferative effects on human cancer cell lines.</p>
    Formula:C25H38O4
    Color and Shape:Solid
    Molecular weight:402.57
  • BF1

    CAS:
    <p>BF1 is an inhibitor of HAT (histone acetyltransferase) active both in vitro and in vivo.</p>
    Formula:C12H12ClN3S
    Color and Shape:Solid
    Molecular weight:265.76
  • Farnesylthiotriazole

    CAS:
    <p>Farnesylthiotriazole is a persistent PKC activator agent.</p>
    Formula:C17H27N3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:305.48
  • Tenovin-D3

    CAS:
    <p>Tenovin-D3 is a sirtuin SirT2 inhibitor. It acts by increasing p21 (CDKN1A) expression in a p53-independent manner.</p>
    Formula:C22H27Cl3N4O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:533.9
  • ML399

    CAS:
    <p>ML399 inhibits menin-MLL interaction, targeting MLL leukemia cells with selective, potent action.</p>
    Formula:C27H28FN3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:445.53
  • iBRD4-BD1

    CAS:
    <p>iBRD4-BD1 inhibits BRD4 bromodomain selectively with 12 nM IC50, useful in inflammation and cancer research.</p>
    Formula:C29H30F3N5O
    Color and Shape:Solid
    Molecular weight:521.58
  • HIF-IN-33

    CAS:
    <p>HIF-IN-33 is an inhibitor of HIF pathway.</p>
    Formula:C21H17F3N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:414.38
  • CPI-905

    CAS:
    <p>CPI-905 is a potent and selective EZH2 inhibitor with IC50 value of 39.5 nM.</p>
    Formula:C18H20N2O5
    Color and Shape:Solid
    Molecular weight:344.36
  • BET-BAY 002

    CAS:
    <p>BET-BAY 002 is an effective BET bromodomain inhibitor demonstrating efficacy in vivo and in vitro against multiple myeloma and leukaemia models.</p>
    Formula:C22H18ClN5O
    Color and Shape:Solid
    Molecular weight:403.86
  • Fagaronine chloride

    CAS:
    <p>Fagaronine chloride is a potent inhibitor of Topoisomerases I.</p>
    Formula:C21H20ClNO4
    Color and Shape:Solid
    Molecular weight:385.84
  • HDAC6-IN-5

    CAS:
    <p>HDAC6-IN-5 (11b), potent HDAC6 blocker, crosses BBB, IC50: 0.025μM, hinders Aβ1-42/AChE aggregation, boosts neurites, low toxicity.</p>
    Formula:C20H14BrN3O2
    Color and Shape:Solid
    Molecular weight:408.25
  • Lobelane Hydrochloride

    CAS:
    <p>Lobelane Hydrochloride is a vesicular monoamine transporter-2 (VMAT2) inhibitor.</p>
    Formula:C22H30ClN
    Color and Shape:Solid
    Molecular weight:343.93
  • TP-238

    CAS:
    <p>"TP-238: Potent CECR2/BPTF dual probe; IC50: 30 nM/350 nM. Inhibits BRD9 (pIC50: 5.9); minimal activity on 338 other kinases."</p>
    Formula:C22H30N6O3S
    Color and Shape:Solid
    Molecular weight:458.58
  • CTPB

    CAS:
    <p>CTPB is a potent p300 histone acetyltransferase (HAT) activator that can be used in the preparation of hair growth promoters and/or hair loss treatments.</p>
    Formula:C31H43ClF3NO2
    Purity:99.77%
    Color and Shape:Solid
    Molecular weight:554.13
  • SirReal-1

    CAS:
    <p>SirReal-1 is an effective and selective inhibitor of Sirt2.</p>
    Formula:C18H18N4OS2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:370.49
  • Prospasmine

    CAS:
    <p>Prospasmine is an anticholinergic.</p>
    Formula:C17H28ClNO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:313.87
  • JAK3-IN-12

    CAS:
    <p>JAK3-IN-12 (compound 15k) is a potent inhibitor of JAK3 (IC50: 9.5 nM) and can be used in the study of rheumatoid arthritis.</p>
    Formula:C19H19N5O4S
    Color and Shape:Solid
    Molecular weight:413.45
  • Hns 32

    CAS:
    <p>Hns 32 possesses antiarrhythmic properties in dog and guinea pig hearts. It also has vasodilator action.</p>
    Formula:C24H29N3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:359.51
  • p32 Inhibitor M36

    CAS:
    <p>p32 inhibitor M36 is an inhibitor of p32 mitochondrial protein. It binds directly to p32 and inhibits the p32 association with LyP-1.</p>
    Formula:C23H28N8O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:448.52
  • AMPK activator 1

    CAS:
    <p>AMPK activator 1 is an AMPK activator(compound No.1-75, EC50: &lt;0.1μM).</p>
    Formula:C32H33F3N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:578.62
  • ST7710AA1

    CAS:
    <p>ST7710AA1 inhibits PARP-1, effectively targets in vitro, and overcomes Pgp-associated multidrug resistance.</p>
    Formula:C20H22N4O
    Color and Shape:Solid
    Molecular weight:334.41
  • NCGC00247743

    CAS:
    <p>NCGC00247743 is an inhibitor of histone lysine demethylase KDM4.</p>
    Formula:C24H29N3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:391.51
  • MI-3

    CAS:
    <p>MI-3 (Menin-MLL Inhibitor) (Menin-MLL Inhibitor) is an effective inhibitor of Menin-MLL interaction (IC50: 648 nM).</p>
    Formula:C18H25N5S2
    Purity:98.66% - 99.61%
    Color and Shape:Solid
    Molecular weight:375.55
  • GPI-15427

    CAS:
    <p>GPI-15427: a potent PARP-1 inhibitor, crosses the blood-brain barrier, boosts TMZ's effects on CNS tumors, and sensitizes cancer to radiotherapy.</p>
    Formula:C20H20N4O2
    Color and Shape:Solid
    Molecular weight:348.4
  • Binucleine 2

    CAS:
    <p>Binucleine 2: Drosophila Aurora B kinase inhibitor (Ki=0.36μM), dose-dependent, minimal effect on human/X. laevis kinases, disrupts mitosis in fly cells.</p>
    Formula:C13H11ClFN5
    Color and Shape:Solid
    Molecular weight:291.71
  • GSK926

    CAS:
    <p>GSK926 is a selective, SAM-competitive, and cell-active EZH2 inhibitor.</p>
    Formula:C29H35N7O2
    Color and Shape:Solid
    Molecular weight:513.63
  • CREBBP-IN-9

    CAS:
    <p>CREBBP-IN-9, a CREBBP inhibitor, acts on the bromodomain of the protein.</p>
    Formula:C16H15N5O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:341.39
  • CPI-1612

    CAS:
    <p>CPI-1612: Oral EP300/CBP HAT inhibitor, IC50 8.1 nM, has anticancer properties.</p>
    Formula:C27H26N6O
    Color and Shape:Solid
    Molecular weight:450.53
  • HDAC-IN-28

    CAS:
    <p>HDAC-IN-28 is a novel inhibitor of HDAC that significantly inhibits tumour growth and metastasis.</p>
    Formula:C23H26N4O4S
    Color and Shape:Solid
    Molecular weight:454.54
  • SDR-04

    CAS:
    <p>SDR-04 inhibits BRD4-BD1 with high affinity, suppressing MV4;11 cancer cell growth as a BET inhibitor.</p>
    Formula:C19H16N4O2
    Color and Shape:Solid
    Molecular weight:332.36
  • H8-A5

    CAS:
    <p>H8-A5, a HDAC8 inhibitor, shows antiproliferation activity in MDA-MB-231 cancer cells.</p>
    Formula:C14H9F3N2O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:326.29
  • ZLD2218

    CAS:
    <p>ZLD2218, a potent inhibitor of BRD4 with an IC50 value of 107 nM, has been demonstrated to mitigate kidney injury and fibrosis through extensive studies.</p>
    Formula:C22H18N4O
    Color and Shape:Solid
    Molecular weight:354.4
  • TK4g

    CAS:
    <p>TK4g, a potent JAK inhibitor, has IC50s of 12.61 nM (JAK2) &amp; 15.80 nM (JAK3); promising for lymphoid diseases &amp; leukemia research.</p>
    Formula:C19H19N3O4S
    Color and Shape:Solid
    Molecular weight:385.44
  • BRD4 Inhibitor-19

    CAS:
    <p>BRD4 inhibitors -19 are BET inhibitors that act on BRD4-BD1 (IC50: 55 nM) and can be used to study multiple myeloma.</p>
    Formula:C29H25N5O3
    Color and Shape:Solid
    Molecular weight:491.54
  • Arazine

    CAS:
    <p>Arazine, a cell-permeable G protein modulator, is an isoprenylcysteine methyltransferase substrate.</p>
    Formula:C20H33NO3S
    Purity:90%
    Color and Shape:Solid
    Molecular weight:367.55
  • PARP1-IN-11

    CAS:
    <p>PARP1-IN-11 is a potent PARP1 inhibitor (IC50=0.082 μM), also reducing PARP3, TNKS1, and TNKS2 activity.</p>
    Formula:C16H12N2O4
    Color and Shape:Solid
    Molecular weight:296.28
  • WD2000-012547

    CAS:
    <p>WD2000-012547 is a selective inhibitor of poly(ADP-ribose)-polymerase (PARP-1) (pKi: 8.221).</p>
    Formula:C17H14N2O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:262.31
  • NV03

    CAS:
    <p>NV03 is a selective antagonist of the UHRF1-H3K9me3 interaction (Kd=2.4 μM) for cancer research. a ligand for E3 ligases in PROTAC synthesis.</p>
    Formula:C19H27N5O2S
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:389.52
  • MS453

    CAS:
    <p>MS453 is a potent and selective SETD8 inhibitor with an IC50 value of 804 nM.</p>
    Formula:C20H27N5O3
    Color and Shape:Solid
    Molecular weight:385.46
  • NR-160

    CAS:
    <p>NR-160 is a selective HDAC6 inhibitor (IC50=0.03μM), weaker on HDAC1-4,8, toxic to 7 cancer lines, boosts bortezomib and anthracycline effects.</p>
    Formula:C25H21F3N6O3
    Color and Shape:Solid
    Molecular weight:510.47
  • M122

    CAS:
    <p>M122 is a selective histone deacetylase HDAC1 and HDAC2 inhibitor and potent antitumor agent.</p>
    Formula:C24H25N5OS2
    Color and Shape:Solid
    Molecular weight:463.62
  • UMB-32

    CAS:
    <p>UMB-32: Potent, selective BRD4 inhibitor, Kd 550 nM, IC50 637 nM, also targets TAF1.</p>
    Formula:C21H23N5O
    Color and Shape:Solid
    Molecular weight:361.44
  • CTK7A

    CAS:
    <p>CTK7A is a water-soluble inhibitor of p300. CTK7A inhibits tumor growth in xenografted mice.</p>
    Formula:C28H24N2NaO6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:507.498
  • Bromodomain inhibitor-10

    CAS:
    <p>Bromodomain inhibitor-10 (compound 128) suppresses BRD4-1/2 with Kd 15 nM/2.5 μM and curbs IL12p40 production.</p>
    Formula:C20H20N4O3
    Color and Shape:Solid
    Molecular weight:364.4
  • MAT2A inhibitor 1

    CAS:
    <p>MAT2A inhibitor 1 is an inhibitor of methionine adenosyltransferase 2A (MATA2) (IC50 &lt; l00 nM).</p>
    Formula:C31H22N6OS
    Color and Shape:Solid
    Molecular weight:526.61
  • FNDR-20123 free base

    CAS:
    <p>FNDR-20123 is a safe, oral first-in-class anti-malarial HDAC inhibitor with low IC50s against Plasmodium and human HDACs.</p>
    Formula:C21H23N5O2
    Color and Shape:Solid
    Molecular weight:377.44
  • TAK-418

    CAS:
    <p>TAK-418 is an orally active LSD1/KDM1A inhibitor with a 2.9 nM IC50, potential for autism therapy.</p>
    Formula:C17H25ClN2O2S
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:356.91
  • SB-429201

    CAS:
    <p>SB-429201 is an effective, selective inhibitor of HDAC1.</p>
    Formula:C28H24N2O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:436.5
  • CAY10669

    CAS:
    <p>CAY10669 inhibits PCAF (IC50 = 662 μM), is twice as potent as anacardic acid, and reduces H4 acetylation in HepG2 cells at 30-60 μM.</p>
    Formula:C20H22O4
    Color and Shape:Solid
    Molecular weight:326.39
  • JNJ-7925476 free base

    CAS:
    <p>JNJ-7925476 is an TRI antidepressant agent.</p>
    Formula:C20H19N
    Purity:98%
    Color and Shape:Solid
    Molecular weight:273.37
  • PF-00956980

    CAS:
    <p>PF-00956980: reversible JAK inhibitor, IC50: JAK1 (2.2μM), JAK2 (23.1μM), JAK3 (59.9μM), for lung/skin inflammation research.</p>
    Formula:C18H26N6O
    Color and Shape:Solid
    Molecular weight:342.44
  • UNC6212 (Kme2)


    <p>UNC6212 (Kme2), a dimethyllysine (Kme2)-containing ligand, has a K D for CBX5 of 5.7 μM .</p>
    Formula:C39H53N7O11
    Color and Shape:Solid
    Molecular weight:795.88
  • BAY-598 R-isomer

    CAS:
    <p>BAY-598 R-isomer, a SMYD2-selective inhibitor, is the R-enantiomer of BAY589, not targeting PAR1.</p>
    Formula:C22H20Cl2F2N6O3
    Color and Shape:Solid
    Molecular weight:525.34
  • J1075

    CAS:
    <p>J1075 is an histone deacetylase 8 (HDAC8) inhibitor.</p>
    Formula:C9H6ClNO2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:227.67
  • S-Aristeromycinylhomocysteine

    CAS:
    <p>S-Aristeromycinylhomocysteine is an inhibitor of adenosylmethionine decarboxylase.</p>
    Formula:C15H22N6O4S
    Color and Shape:Solid
    Molecular weight:382.44
  • (R)-OR-S1

    CAS:
    <p>(R)-OR-S1 is a SAM-competitive, highly selective, orally bioavailable dual inhibitor of EZH1/2.</p>
    Formula:C26H34BrN3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:532.47