Chromatin/Epigenetics

Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.

Subcategories of "Chromatin/Epigenetics"

Aurora Kinase
(114 products)

Found 2567 products of "Chromatin/Epigenetics"

Purity (%)

100

products per page.

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BAZ2-ICR
CAS:
- 1665195-94-7
BAZ2-ICR is an epigenetic chemical probe and it also is a potent, selective, cell active and orally active BAZ2A/B bromodomains inhibitor with IC50s of 130 nM and 180 nM, and Kds of 109 nM and 170 nM, respectively. BAZ2-ICR shows 10-15-fold selectivity for binding BAZ2A/B over CECR2 and >100-fold selectivity over all other bromodomains.
Formula:C₂₀H₁₉N₇
Purity:98%
Color and Shape:Solid
Molecular weight:357.41
Ref: TM-T14512
50mg
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100mg
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Lerzeparib
CAS:
- 2459693-01-5
Lerzeparib is a PARP (ADP-ribose polymerase) inhibitor that exhibits antineoplastic activity [1].
Formula:C₂₁H₂₀FN₃O₂
Purity:98%
Color and Shape:Solid
Molecular weight:365.4
Ref: TM-T79853
ne
Discontinued
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5mg
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50mg
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JAK-IN-27
CAS:
- 2673176-36-6
JAK-IN-27, also known as compound 1, is an orally active, potent inhibitor of the JAKS family kinases, displaying inhibitory concentrations (IC50s) of 3.0 nM
Formula:C₂₀H₂₁F₂N₇O
Purity:98%
Color and Shape:Solid
Molecular weight:413.42
Ref: TM-T79110
ne
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5mg
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50mg
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Antitumor agent-104
CAS:
- 2245272-16-4
Antitumor Agent-104 (Compound 9) serves as an antineoplastic by impeding DNA repair mechanisms in tumor cells, primarily through the inhibition of PARP1 enzyme
Formula:C₃₁H₃₃FN₆O₃
Purity:98%
Color and Shape:Solid
Molecular weight:556.63
Ref: TM-T79265
ne
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5mg
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50mg
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BB-Cl-Amidine hydrochloride
CAS:
- 2436747-41-8
BB-Cl-Amidine hydrochloride is an inhibitor of peptidylarginine deminase (PAD) [1].
Formula:C₂₆H₂₇Cl₂N₅O
Purity:98%
Color and Shape:Solid
Molecular weight:496.43
Ref: TM-T10482L
50mg
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100mg
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BET BD2-IN-3
CAS:
- 2677039-66-4
BET BD2-IN-3 (compound I-58), a BET inhibitor specifically targeting the BD2 domain, can be radiolabeled with [11C] for use in positron emission tomography (PET) imaging. PET studies with [11C]BD2-IN-3 in mice have demonstrated appropriate biodistribution in peripheral organs and tissues.
Formula:C₂₉H₃₀N₄O
Color and Shape:Solid
Molecular weight:450.58
Ref: TM-T89982
10mg
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50mg
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PARP7-IN-16 free base
CAS:
- 2136325-05-6
PARP7-IN-16 free base is the freebase form of PARP7-IN-16. As a selective oral inhibitor of PARP-1/2/7, it demonstrates IC50 values of 0.94, 0.87, and 0.21 nM, respectively. This compound is utilized in the research of breast and prostate cancer.
Formula:C₂₅H₂₇FN₄O₄
Color and Shape:Solid
Molecular weight:466.50
Ref: TM-T200703
10mg
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25mg
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50mg
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100mg
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