Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2611 products of "Chromatin/Epigenetics"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
PF-04577806
CAS:PF-04577806: potent & selective PKC inhibitor, ATP competitive, blocks PKCα/βI/βII/γ/θ (IC50: 2.4-45.9 nM), may reverse diabetic retinal leakage.Formula:C26H37N7O3Color and Shape:SolidMolecular weight:495.628Lyngbyatoxin A
CAS:Lyngbyatoxin A is an indole alkaloid from blue-green alga Lyngbya majuscula Gomont; responsible for dermatitis known as "swimmers' itch" in Hawaii.
Formula:C27H39N3O2Color and Shape:SolidMolecular weight:437.62DNA Damage & Repair Compound Library
A unique collection of xnum DNA Damage & Repair related compounds for high throughput screening (HTS) and high content screening (HCS);
Color and Shape:Odour SolidPumecitinib
CAS:Pumecitinib is a Janus kinase (JAK) inhibitor. Pumecitinib exhibits anti-inflammatory activity.
Formula:C17H20N8O2SPurity:99.94%Color and Shape:SoildMolecular weight:400.46Tyrosine Kinase Inhibitor Library
A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase relatedColor and Shape:Odour SolidRef: TM-L2200
1mgTo inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquireINCB059872
CAS:INCB059872: potent, oral, selective LSD1 inhibitor for myeloid leukemia research.Formula:C23H34N2O3Color and Shape:SolidMolecular weight:386.536BRD4 degrader AT1
CAS:BRD4 degrader AT1 is a highly selective Brd4 degrader based on PROTAC technology, with a Kd of 44 nM for Brd4BD2 in cells.Formula:C48H58ClN9O5S3Purity:98%Color and Shape:SolidMolecular weight:972.68JPS036
CAS:JPS036, a benzamide-based VHL E3-ligase PROTAC, potently degrades HDAC1/2, increasing gene expression and apoptosis in HCT116 cells.Formula:C51H66FN7O7SColor and Shape:SolidMolecular weight:940.18GSK 591 dihydrochloride
CAS:Strong PRMT5 inhibitor with 4 nM IC50, surpassing other PRMTs; halts MCL growth in lab tests.Formula:C22H30Cl2N4O2Color and Shape:SolidMolecular weight:453.41MS33
CAS:MS33 degrades WDR5 protein, Kd 870 nM (VCB), 120 nM (WDR5); uses VHL ligase, aids acute myeloid leukemia study.Formula:C64H84F3N11O7SColor and Shape:SolidMolecular weight:1208.5OKI-006
CAS:OKI-006 is an oral HDAC inhibitor with potential for cancer research, derived from largazole.Formula:C21H30N4O5S2Color and Shape:SolidMolecular weight:482.62JB300
CAS:JB300 is a PROTAC-based compound that serves as a highly selective degrader of Aurora A, with a DC50 of 30 nM. It is utilized in cancer research. JB300 comprises the PROTAC target protein ligand MK-5108 [pink part], E3 ligase ligand Thalidomide-O-COOH [blue part], and PROTAC Linker Boc-NH-PEG2-C2-NH2 [black part]. The conjugate of the E3 ubiquitin ligase ligand and linker is Thalidomide-O-COOH-NH2-C2-PEG2-NH-Boc.Formula:C43H45ClFN7O10SColor and Shape:SolidMolecular weight:906.375EZH2-IN-15
CAS:A compound inhibits EZH2, overexpressed in cancers, affecting Treg activity and innate immunity.Formula:C32H44N4O4Purity:99.88%Color and Shape:SolidMolecular weight:548.72Ref: TM-T67883
1mg130.00€5mg258.00€10mg339.00€25mg578.00€50mg879.00€100mg1,314.00€200mg1,918.00€1mL*10mM (DMSO)311.00€XF067-68
CAS:XF067-68 is a PROTAC for targeted degradation of WD40 repeat domain protein 5 ( WDR5 )[1] .Formula:C52H59F4N9O7SColor and Shape:SolidMolecular weight:1030.14PROTAC CBP/P300 Degrader-1
CAS:PROTAC CBP/P300 Degrader-1 effectively reduces cancer cell viability by degrading CBP/P300.Formula:C46H53F2N11O6Color and Shape:SolidMolecular weight:893.998Go6976
CAS:Go6976 is a PKC inhibitor, widely used in research to probe PKC functions in health and disease.Formula:C24H18N4OPurity:95.89%Color and Shape:Off-White To Yellow SolidMolecular weight:378.43PRO-HD3
PRO-HD3 is a cell-specific, PROTAC-based degrader targeting HDAC6 [1].Purity:98%Color and Shape:Odour SolidKB02-JQ1
CAS:KB02-JQ1: potent BRD4-degrading PROTAC, stable, specific; doesn't affect BRD2/3, modifies DCAF16 for action.Formula:C38H43Cl2N7O6SPurity:98%Color and Shape:SoildMolecular weight:796.77MS9024
MS9024 is a degrader of DNA methyltransferase 1 (DNMT1), facilitating its degradation in HCT116 cells via the ubiquitin-proteasome pathway, with a DC50 of 35 nM (DC50 values are 254 nM in MDA-MB-468 and 101 nM in H1299). Additionally, MS9024 inhibits DNMT1 with an IC50 of 0.43 μM.Color and Shape:Odour SolidPRMT5 ligand 1
CAS:PRMT5ligand 1 is a ligand of PRMT5, used as a target protein ligand in the synthesis of the PROTAC degrader MS4322.Formula:C20H26N6O2Color and Shape:SolidMolecular weight:382.459
