Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2235 products of "Chromatin/Epigenetics"
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AG490
CAS:<p>AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.</p>Formula:C17H14N2O3Purity:98.6% - 99.39%Color and Shape:Yellow SolidMolecular weight:294.3Pyridone 6
CAS:<p>Pyridone 6, a selective JAK1/2/3 and Tyk2 inhibitor with IC50s: JAK1=15 nM, JAK2=1 nM, JAK3 (Ki=5 nM), Tyk2=1 nM; weakly binds other kinases (130 nM-10 μM).</p>Formula:C18H16FN3OPurity:97.1% - 98.74%Color and Shape:SolidMolecular weight:309.34DL-α-Hydroxyglutaric acid disodium salt
CAS:<p>DL-α-Hydroxyglutaric acid disodium salt (disodium 2-hydroxypentanedioate) is an α -hydroxyacid formed from the hydrolysis of (R) -5-oxy-2-tetrahydrofuran</p>Formula:C5H6Na2O5Purity:≥98%Color and Shape:SolidMolecular weight:192.08BMS-911543
CAS:<p>BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2.</p>Formula:C23H28N8OPurity:97.69% - 99.98%Color and Shape:SolidMolecular weight:432.52Phthalazinone pyrazole
CAS:<p>Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.</p>Formula:C18H15N5OPurity:97.03%Color and Shape:SolidMolecular weight:317.34Filgotinib
CAS:<p>Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.</p>Formula:C21H23N5O3SPurity:98.03% - ≥95%Color and Shape:SolidMolecular weight:425.51,5-Isoquinolinediol
CAS:<p>1,5-Isoquinolinediol, a PARP1 inhibitor (IC50: 0.39 μM), is used in DNA repair and cell death studies.</p>Formula:C9H7NO2Purity:98.29% - 99.35%Color and Shape:Of White To White PowderMolecular weight:161.16OG-L002
CAS:<p>OG-L002 is an effective and selective LSD1 inhibitor (IC50: 20 nM), showing 69- and 36-fold selectivity over MAO-A and MAO-B, respectively.</p>Formula:C15H15NOPurity:97.05% - 98.62%Color and Shape:SolidMolecular weight:225.29666-15
CAS:<p>666-15 is a selective CREB inhibitor with an IC50 of 81 nM. 666-15 can effectively inhibit the growth of breast cancer.Cost-effective and quality-assured.</p>Formula:C33H31Cl2N3O5Purity:99.41% - 99.88%Color and Shape:SolidMolecular weight:620.52WHI-P97
CAS:<p>WHI-P97 is a rationally designed potent inhibitor of JAK-3.</p>Formula:C16H13Br2N3O3Purity:99.93%Color and Shape:SolidMolecular weight:455.12,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide
CAS:<p>2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity and physicochemical properties.</p>Formula:C16H13Cl2N3O2Purity:98.77%Color and Shape:SolidMolecular weight:350.2DR2313
CAS:<p>DR2313 is a competitive inhibitor of poly(ADP-ribose) polymerase (IC50: 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). It also has neuroprotective.</p>Formula:C8H10N2OSPurity:98.65%Color and Shape:SolidMolecular weight:182.24Danusertib
CAS:<p>Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.</p>Formula:C26H30N6O3Purity:97.88% - 98.79%Color and Shape:White PowderMolecular weight:474.55Upadacitinib
CAS:<p>Upadacitinib (ABT-494), a selective JAK1 inhibitor, is researched for autoimmune diseases; IC50: 43 nM.</p>Formula:C17H19F3N6OPurity:98.96% - 99.94%Color and Shape:SolidMolecular weight:380.37MM-102 TFA
CAS:<p>MM-102 TFA is a potent WDR5/MLL inhibitor with IC50 of 2.4 nM; it disrupts MLL1-WDR5 interaction, impeding H3K4 HMT activity.</p>Formula:C37H50F5N7O6Purity:99.4% - 99.78%Color and Shape:SolidMolecular weight:783.83I-BRD9
CAS:<p>I-BRD9 (GSK602) is the first selective cellular inhibitor for BRD9 with pIC50 of 7.3.</p>Formula:C22H22F3N3O3S2Purity:98.16% - 99.51%Color and Shape:SolidMolecular weight:497.55SNS-314
CAS:<p>SNS-314 inhibits Aurora kinases A and B, blocking cell division in AK-overexpressing tumors.</p>Formula:C18H15ClN6OS2Purity:98%Color and Shape:SolidMolecular weight:430.93G007-LK
CAS:<p>G007-LK is a selective inhibitor of TNKS1 and TNKS2, with IC50s of 46 nM and 25 nM, respectively.</p>Formula:C25H16ClN7O3SPurity:97.63% - 98.17%Color and Shape:SolidMolecular weight:529.96JQKD82
CAS:<p>JQKD82 is a selective inhibitor of KDM5 and increases H3K4me3. JQKD82 can be used in studies about the treatment of multiple myeloma.</p>Formula:C27H40N4O5Purity:100.00%Color and Shape:SolidMolecular weight:500.63Curculigoside
CAS:<p>1.</p>Formula:C22H26O11Purity:99.85%Color and Shape:SolidMolecular weight:466.44
