Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2613 products of "Chromatin/Epigenetics"
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PROTAC BRD4 Degrader-37
PROTACBRD4 Degrader-37 is a PROTACBRD4 degrader with a DC50 of 36.4 nM and a Dmax of 73% in PANC-1 cells. It exhibits cytotoxicity against PANC-1 cells with a GI50 of 0.282 μM. PROTACBRD4 Degrader-37 is applicable for cancer research.Color and Shape:Odour SolidCAM2602
CAM2602 is an inhibitor of Aurora A-TPX2 interaction, demonstrating a binding affinity of 19 nM with Aurora A. This compound has been shown to inhibit the growth of pancreatic cancer cells. In solid tumor xenograft models, CAM2602 increases the proportion of PH3-positive cells while decreasing the ratio of P-Thr288Aurora A-positive cells, ultimately inhibiting tumor growth.Color and Shape:Odour SolidGSK3735967
CAS:GSK3735967: DNMT1 inhibitor, IC50 40 nM, dicyanopyridine core, binds hemimethylated CpG, interacts with H4K20me3.Formula:C25H31N7OSColor and Shape:SolidMolecular weight:477.62ATF3 inducer 1
CAS:ATF3 inducer 1 is an ATF3 inducer with lipid-lowering activity, alleviating glucose intolerance and insulin resistance induced by high-fat diet (HFD).Formula:C12H10N2O3Purity:99.04%Color and Shape:SoildMolecular weight:230.22PROTAC BRD4 Degrader-13
CAS:PROTAC BRD4 Degrader-13 targets VHL and BRD4, degrading BRD4 with DC50 of 0.025/6.0 nM in PC3 cells when linked to STEAP1/CLL1 antibodies.Formula:C68H85F2N11O17P2S2Color and Shape:SolidMolecular weight:1492.55Fibrostatin C
CAS:Fibrostatin C is an inhibitor of prolyl 4-hydroxylase. It is produced by Streptomyces catenulae subsp.Formula:C18H19NO8SColor and Shape:SolidMolecular weight:409.41QC-182
CAS:QC-182 is a potent p300/CBP PROTAC degrader. It reduces p300 protein levels in SK-HEP-1 cells with a DC50 of 93 nM. QC-182 effectively inhibits cell growth in SK-HEP-1 and JHH7 cell lines, with IC50 values of 0.733 μM and 0.477 μM, respectively. QC-182 is applicable for hepatocellular carcinoma (HCC) research.Formula:C44H42F2N8O6Molecular weight:816.85VHL-IN-1
VHL-IN-1 (compound 30), a ubiquitin E3 ligase von Hippel-Lindau (VHL) inhibitor with a dissociation constant (Kd) of 37 nM, potently stabilizes HIF-1α andFormula:C28H37FN4O4SPurity:98%Color and Shape:SolidMolecular weight:544.68MZP-54
CAS:MZP-54 is a selective degrader of BRD3/4 based on PROTAC technology(Kd of 4 nM for Brd4BD2)Formula:C55H66ClN7O9SPurity:98%Color and Shape:SolidMolecular weight:1036.67dAURK-4
CAS:dAURK-4, a derivative of Alisertib, functions as a potent and selective degrader of AURKA (Aurora A), exhibiting anticancer properties [1].Formula:C52H52ClFN8O12Color and Shape:SolidMolecular weight:1035.47Phoenixin-20
CAS:Phoenixin-20 (PNX-20) is a vertebrate bioactive peptide exhibiting hormone-like actions, stimulating the hypothalamo-pituitary-gonadal axis to regulateFormula:C101H153N25O29Purity:98%Color and Shape:SolidMolecular weight:2181.45CPI-268456
CAS:CPI-268456 is a compound which has bioactive.Formula:C20H15Cl2N3O2Color and Shape:SolidMolecular weight:400.26Myelin Basic Protein
CAS:Myelin basic protein (MBP) is a protein believed to be important in the process of myelination of nerves in the nervous system.Formula:C60H103N21O17Purity:98%Color and Shape:SolidMolecular weight:1390.59Flindersine
CAS:Flindersine is a useful organic compound for research related to life sciences. The catalog number is T124718 and the CAS number is 523-64-8.Formula:C14H13NO2Color and Shape:SolidMolecular weight:227.263PROTAC BRD4 Degrader-15
CAS:PROTAC BRD4 Degrader-15 targets von Hippel-Lindau and BRD4 with IC50s 7.2/8.1 nM and degrades BRD4 in cancer cells.Formula:C57H62F2N10O10S2Color and Shape:SolidMolecular weight:1149.3RK 286D
CAS:RK 286D is an indolocarbazole antibiotic.Formula:C26H23N3O4Color and Shape:SolidMolecular weight:441.48TNKS-2-IN-2
CAS:TNKS-2-IN-2 is a TNKS2 selective inhibitor (IC50: 22 nM) with potential anti-tumour activity for the study of colon cancer lung cancer and breast cancer.Formula:C26H23N3O6Purity:99.45%Color and Shape:SoildMolecular weight:473.48PROTAC BRD4 Degrader-21
CAS:PROTAC BRD4 Degrader-21 (Comp 74), a potent degrader of BRD4, has demonstrated substantial inhibition of tumor growth in mouse xenograft models, showing itsFormula:C47H54Cl2N10O4SPurity:98%Color and Shape:SolidMolecular weight:925.97TPOP146
CAS:TPOP146 is a selective CBP/P300 benzoxazepine bromodomain inhibitor (Kd: 134 nM and 5.02 μM for CBP and BRD4).Formula:C27H35N3O5Purity:98%Color and Shape:SolidMolecular weight:481.58
