Chromatin/Epigenetics

Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.

Subcategories of "Chromatin/Epigenetics"

Aurora Kinase
(94 products)

Found 2235 products of "Chromatin/Epigenetics"

Purity (%)

100

products per page.

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WHI-P97
CAS:
- 211555-05-4
WHI-P97 is a rationally designed potent inhibitor of JAK-3.
Formula:C₁₆H₁₃Br₂N₃O₃
Purity:99.93%
Color and Shape:Solid
Molecular weight:455.1
Ref: TM-T4657
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G007-LK
CAS:
- 1380672-07-0
G007-LK is a selective inhibitor of TNKS1 and TNKS2, with IC50s of 46 nM and 25 nM, respectively.
Formula:C₂₅H₁₆ClN₇O₃S
Purity:97.63% - 98.17%
Color and Shape:Solid
Molecular weight:529.96
Ref: TM-T6842
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SGC707
CAS:
- 1687736-54-4
SGC707 is a potent, selective, and cell-active allosteric inhibitor of PRMT3.
Formula:C₁₆H₁₈N₄O₂
Purity:98.45% - 99.79%
Color and Shape:Solid
Molecular weight:298.34
Ref: TM-T3084
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JQKD82
CAS:
- 2410512-38-6
JQKD82 is a selective inhibitor of KDM5 and increases H3K4me3. JQKD82 can be used in studies about the treatment of multiple myeloma.
Formula:C₂₇H₄₀N₄O₅
Purity:100.00%
Color and Shape:Solid
Molecular weight:500.63
Ref: TM-T39989
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Curculigoside
CAS:
- 85643-19-2
1.
Formula:C₂₂H₂₆O₁₁
Purity:99.85%
Color and Shape:Solid
Molecular weight:466.44
Ref: TM-T6S1966
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Pyridone 6
CAS:
- 457081-03-7
Pyridone 6, a selective JAK1/2/3 and Tyk2 inhibitor with IC50s: JAK1=15 nM, JAK2=1 nM, JAK3 (Ki=5 nM), Tyk2=1 nM; weakly binds other kinases (130 nM-10 μM).
Formula:C₁₈H₁₆FN₃O
Purity:97.1% - 98.74%
Color and Shape:Solid
Molecular weight:309.34
Ref: TM-T3080
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GN44028
CAS:
- 1421448-26-1
GN44028 is a HIF-1 inhibitor with an IC50 of 14 nM, stopping HIF-1α activity but not mRNA or protein levels, or dimerization.
Formula:C₁₈H₁₅N₃O₂
Purity:99.52%
Color and Shape:Solid
Molecular weight:305.33
Ref: TM-T15396
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MPT0G211 mesylate
CAS:
- 2151854-33-8
MPT0G211 mesylate: potent, selective HDAC6 inhibitor (IC50=0.291nM), oral, BBB-penetrating, anti-tau and metastasis, potential anticancer.
Formula:C₁₈H₁₉N₃O₅S
Color and Shape:Solid
Molecular weight:389.43
Ref: TM-T61753
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CPI203
CAS:
- 202591-23-9
CPI203 (CPI 203) is an effective BET bromodomain inhibitor (IC50: 37 nM for BRD4).
Formula:C₁₉H₁₈ClN₅OS
Purity:99.13% - 99.77%
Color and Shape:Solid
Molecular weight:399.9
Ref: TM-T2442
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Upadacitinib
CAS:
- 1310726-60-3
Upadacitinib (ABT-494), a selective JAK1 inhibitor, is researched for autoimmune diseases; IC50: 43 nM.
Formula:C₁₇H₁₉F₃N₆O
Purity:98.96% - 99.94%
Color and Shape:Solid
Molecular weight:380.37
Ref: TM-T7503
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ZM-447439
CAS:
- 331771-20-1
ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, Lck; minimal impact on CDK1/2/4, Plk1, Chk1.
Formula:C₂₉H₃₁N₅O₄
Purity:99.11% - 99.59%
Color and Shape:Pale Yellow Solid
Molecular weight:513.59
Ref: TM-T6077
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Pacritinib
CAS:
- 937272-79-2
Pacritinib (SB1518) (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 nM, in cell-free assays).
Formula:C₂₈H₃₂N₄O₃
Purity:99.25% - 99.49%
Color and Shape:Solid
Molecular weight:472.58
Ref: TM-T6020
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IOX1
CAS:
- 5852-78-8
IOX1, a broad-spectrum 2OG oxygenase inhibitor, IC50: KDM4A - 0.6uM, KDM3A - 0.1uM.
Formula:C₁₀H₇NO₃
Purity:99.67%
Color and Shape:Solid
Molecular weight:189.17
Ref: TM-T6545
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1,5-Isoquinolinediol
CAS:
- 5154-02-9
1,5-Isoquinolinediol, a PARP1 inhibitor (IC50: 0.39 μM), is used in DNA repair and cell death studies.
Formula:C₉H₇NO₂
Purity:98.29% - 99.35%
Color and Shape:Of White To White Powder
Molecular weight:161.16
Ref: TM-T7042
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MRTX-1719
CAS:
- 2630904-45-7
MRTX-1719 is a potent and selective inhibitor of the PRMT5/MTA complex with an IC50 value of <10 nM against PRMT5/MTAMTAPDELSDMA cell lines.Cost-effective and quality-assured.
Formula:C₂₃H₁₈ClFN₆O₂
Purity:98.27% - 99.18%
Color and Shape:Solid
Molecular weight:464.88
Ref: TM-T40254
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Bisindolylmaleimide IV
CAS:
- 119139-23-0
Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55 μM)
Formula:C₂₀H₁₃N₃O₂
Purity:98.83%
Color and Shape:Dark Red Solid
Molecular weight:327.34
Ref: TM-T7659
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AZ6102
CAS:
- 1645286-75-4
AZ6102: Potent TNKS1/2 inhibitor, 100x selective over PARPs, IC50 = 5 nM in DLD-1 Wnt pathway.
Formula:C₂₅H₂₈N₆O
Purity:97.98% - 99.91%
Color and Shape:Solid
Molecular weight:428.53
Ref: TM-T6768
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FM-381
CAS:
- 2226521-65-7
FM381, a JAK3 inhibitor with 127 pM IC50, is 410-3600x more selective over JAK1/2/TYK2.
Formula:C₂₄H₂₄N₆O₂
Purity:98.44%
Color and Shape:Solid
Molecular weight:428.49
Ref: TM-T5091
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RVX-297
CAS:
- 1044871-04-6
RVX-297 selectively inhibits BD2 domains of BET bromodomains, binding preferentially to BET proteins.
Formula:C₂₄H₂₉N₃O₄
Purity:99.62%
Color and Shape:Solid
Molecular weight:423.5
Ref: TM-T28628
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666-15
CAS:
- 1433286-70-4
666-15 is a selective CREB inhibitor with an IC50 of 81 nM. 666-15 can effectively inhibit the growth of breast cancer.Cost-effective and quality-assured.
Formula:C₃₃H₃₁Cl₂N₃O₅
Purity:99.41% - 99.88%
Color and Shape:Solid
Molecular weight:620.52
Ref: TM-T5318