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Chromatin/Epigenetics

Chromatin/Epigenetics

Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.

Subcategories of "Chromatin/Epigenetics"

Found 2235 products of "Chromatin/Epigenetics"

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  • WHI-P97

    CAS:
    <p>WHI-P97 is a rationally designed potent inhibitor of JAK-3.</p>
    Formula:C16H13Br2N3O3
    Purity:99.93%
    Color and Shape:Solid
    Molecular weight:455.1
  • AZ505

    CAS:
    <p>AZ505 is an effective and specific SMYD2 inhibitor (IC50: 0.12 μM).</p>
    Formula:C29H38Cl2N4O4
    Purity:98.18%
    Color and Shape:Solid
    Molecular weight:577.54
  • Reversine

    CAS:
    <p>Reversine, a small synthetic purine analogue (2, 6-disubstituted purine), is a potent inhibitior of Aurora A/B/C(IC50s=150-500 nM).</p>
    Formula:C21H27N7O
    Purity:98% - 98.42%
    Color and Shape:Solid
    Molecular weight:393.49
  • MLN8054

    CAS:
    <p>MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.</p>
    Formula:C25H15ClF2N4O2
    Purity:98.07% - 98.26%
    Color and Shape:Solid
    Molecular weight:476.86
  • Upadacitinib

    CAS:
    <p>Upadacitinib (ABT-494), a selective JAK1 inhibitor, is researched for autoimmune diseases; IC50: 43 nM.</p>
    Formula:C17H19F3N6O
    Purity:98.96% - 99.94%
    Color and Shape:Solid
    Molecular weight:380.37
  • 1,5-Isoquinolinediol

    CAS:
    <p>1,5-Isoquinolinediol, a PARP1 inhibitor (IC50: 0.39 μM), is used in DNA repair and cell death studies.</p>
    Formula:C9H7NO2
    Purity:98.29% - 99.35%
    Color and Shape:Of White To White Powder
    Molecular weight:161.16
  • GN44028

    CAS:
    <p>GN44028 is a HIF-1 inhibitor with an IC50 of 14 nM, stopping HIF-1α activity but not mRNA or protein levels, or dimerization.</p>
    Formula:C18H15N3O2
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:305.33
  • GSK1379725A

    CAS:
    <p>GSK1379725A is a selective BPTF ligand (Kd = 2.8 μM).</p>
    Formula:C23H23FN6O3
    Purity:99.51%
    Color and Shape:Solid
    Molecular weight:450.47
  • Bromosporine

    CAS:
    <p>Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively.</p>
    Formula:C17H20N6O4S
    Purity:99.65% - 99.79%
    Color and Shape:Solid
    Molecular weight:404.44
  • Ruboxistaurin mesylate

    CAS:
    <p>Ruboxistaurin: PKC beta inhibitor, eases oxidative stress, heart issues &amp; nephropathy in diabetic rats, halts retinal neovascularization.</p>
    Formula:C29H32N4O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:564.65
  • UNC1999

    CAS:
    <p>UNC1999 is a orally bioavailable, effective and specific inhibitor of EZH2 (IC50=2 nM) and EZH1 (IC50=45).</p>
    Formula:C33H43N7O2
    Purity:99.19% - >99.99%
    Color and Shape:Solid
    Molecular weight:569.74
  • JQ-1 (carboxylic acid)

    CAS:
    <p>JQ-1 (carboxylic acid) is a cell-permeable BRD4 inhibitor with IC50s of 77 nM for BRD4(1) and 33 nM for BRD4(2)</p>
    Formula:C19H17ClN4O2S
    Purity:99.14% - 99.9%
    Color and Shape:Solid
    Molecular weight:400.88
  • CPI-637

    CAS:
    <p>CPI-637 is a selective and cell-active benzodiazepinone CBP/EP300 bromodomain inhibitor.</p>
    Formula:C22H22N6O
    Purity:99.89% - 99.95%
    Color and Shape:Solid
    Molecular weight:386.45
  • Glucosamine sulfate

    CAS:
    <p>Glucosamine sulfate (D-Glucosaminesulfate) was extracted from synthetic product;Store the product in sealed, cool and dry condition.</p>
    Formula:C6H13NO5·H2SO4
    Purity:99.64%
    Color and Shape:White Crystal
    Molecular weight:277.25
  • 8-CHLOROQUINAZOLIN-4(1H)-ONE

    CAS:
    <p>8-CHLOROQUINAZOLIN-4(1H)-ONE is inhibitor of Poly [ADP-ribose] polymerase 1 (human)</p>
    Formula:C8H5ClN2O
    Purity:98.79%
    Color and Shape:Solid
    Molecular weight:180.59
  • ICG001

    CAS:
    <p>ICG001 antagonizes Wnt signaling, binds CBP with 3 μM IC50, not p300.</p>
    Formula:C33H32N4O4
    Purity:99.06% - 99.95%
    Color and Shape:Solid
    Molecular weight:548.63
  • (R)-(-)-JQ1 Enantiomer

    CAS:
    <p>(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1. (+)-JQ1 is a BET bromodomain inhibitor, acting on BRD4(1/2)(IC50 of 77 nM/33 nM in a cell-free assay)</p>
    Formula:C23H25ClN4O2S
    Purity:99.38%
    Color and Shape:Solid
    Molecular weight:456.99
  • Cerdulatinib

    CAS:
    <p>Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.</p>
    Formula:C20H27N7O3S
    Purity:98.74% - 99.49%
    Color and Shape:Solid
    Molecular weight:445.54
  • JQEZ5

    CAS:
    <p>JQEZ5 is an inhibitor of EZH2 lysine methyltransferase (IC50 = 11.1 nM).</p>
    Formula:C30H38N8O2
    Purity:98.14% - ≥98%
    Color and Shape:Solid
    Molecular weight:542.68
  • Rucaparib hydrochloride

    CAS:
    <p>Rucaparib hydrochloride (AG014699) is an oral PARP inhibitor with Ki 1.4 nM for PARP1 and hinders H6PD, studied in CRPC research.</p>
    Formula:C19H19ClFN3O
    Color and Shape:Solid
    Molecular weight:359.83