Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2615 products of "Chromatin/Epigenetics"
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SIRT-IN-3
CAS:SIRT-IN-3: potent SIRT1 inhibitor (IC50=17μM), 4x selective over SIRT2, 14x over SIRT3 (IC50s: 74μM & 235μM).Formula:C13H12N2OColor and Shape:SolidMolecular weight:212.25AMI-1 free acid
CAS:AMI-1: Potent reversible PRMT inhibitor; IC50: 8.8 μM (hPRMT1), 3.0 μM (yeast-Hmt1p); blocks substrate binding.
Formula:C21H16N2O9S2Purity:97.8%Color and Shape:SolidMolecular weight:504.49IOX1
CAS:IOX1, a broad-spectrum 2OG oxygenase inhibitor, IC50: KDM4A - 0.6uM, KDM3A - 0.1uM.Formula:C10H7NO3Purity:99.67%Color and Shape:SolidMolecular weight:189.17XY1
CAS:XY1 is a very close analogue of SGC707 (a potent, selective, and non-competitive inhibitor of PRMT3 with IC50 of 31 nM), It is intended to be used as aFormula:C17H19N3O2Purity:97.74% - 99%Color and Shape:SolidMolecular weight:297.35AZ960
CAS:AZ960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: <3 nM and0.45 nM).Formula:C18H16F2N6Purity:96.02% - 99.88%Color and Shape:SolidMolecular weight:354.36PF-06409577
CAS:PF-06409577 is an effective, orally active, and specific allosteric activator of AMPK (EC50: 7 nM, for α1β1γ1).Formula:C19H16ClNO3Purity:95.17% - 98.21%Color and Shape:SolidMolecular weight:341.79Ref: TM-T4427
1mg34.00€2mg43.00€5mg63.00€1mL*10mM (DMSO)71.00€10mg100.00€25mg200.00€50mg334.00€100mg537.00€200mg762.00€4-(3-Chlorophenyl)-2(3H)-thiazolone
CAS:4-(3-chlorophenyl)-2,3-dihydro-1,3-thiazol-2-one: a thiazole used to make antifungals, antivirals, and anti-inflammatories.Formula:C9H6ClNOSPurity:95.311%Color and Shape:SolidMolecular weight:211.67UNC0379
CAS:UNC0379 is a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8.Formula:C23H35N5O2Purity:94.41% - 99.97%Color and Shape:SolidMolecular weight:413.56WP1066
CAS:WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3.Formula:C17H14BrN3OPurity:98.92% - 99.73%Color and Shape:SolidMolecular weight:356.22BI-7273
CAS:BI-7273 is an effective, specific, BRD9 BD Inhibitor, which can infiltrate cell.Formula:C20H23N3O3Purity:97.37% - 99.57%Color and Shape:SolidMolecular weight:353.41TCS PIM-1 1
CAS:TCS PIM-1 1 (SC 204330) is a potent ATP-competitive inhibitor of Pim-1 kinase with an IC50 of 50 nM, selective over MEK1/2 and Pim-2.Formula:C18H11BrN2O2Purity:97% - 97.98%Color and Shape:SolidMolecular weight:367.2Ref: TM-T2253
1mg34.00€5mg60.00€1mL*10mM (DMSO)92.00€10mg94.00€25mg177.00€50mg269.00€100mg401.00€200mg580.00€Rucaparib monocamsylate
CAS:Rucaparib monocamsylate (Rucaparib Camsylate) is a PARP inhibitor. Rucaparib Camsylate also displays binding affinity to eight other PARP domains.Formula:C29H34FN3O5SPurity:99.82%Color and Shape:SolidMolecular weight:555.66PI-1840
CAS:PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.Formula:C22H26N4O3Purity:98.82%Color and Shape:SolidMolecular weight:394.47Pacritinib hydrochloride
CAS:Pacritinib HCl: strong JAK2/Wild-type & JAK2V617F inhibitor (IC50: 23/19 nM), used in AML & MF research.Formula:C28H32N4O3·xClHColor and Shape:Solid3-methyl-1,2-dihydroquinolin-2-one
CAS:3-methyl-1,2-dihydroquinolin-2-one is the first known micromolar inhibitors of the ATAD2 bromodomain.Formula:C10H9NOPurity:99.62%Color and Shape:SolidMolecular weight:159.18Ref: TM-T50035
1mg35.00€1mL*10mM (DMSO)62.00€5mg77.00€10mg103.00€25mg170.00€50mg250.00€100mg354.00€200mg480.00€BEBT-908
CAS:BEBT-908 (PI3Kα inhibitor 1) is a selective PI3Kα inhibitor (IC50 <0.1 μM). BEBT-908 also inhibits HDAC (0.1 μM≤IC50≤1 μM).Formula:C23H25N9O3SPurity:99.67%Color and Shape:SolidMolecular weight:507.57Ref: TM-T16529
1mg94.00€5mg222.00€1mL*10mM (DMSO)249.00€10mg334.00€25mg562.00€50mg802.00€100mg1,063.00€200mg1,459.00€Delgocitinib EtOH
CAS:Delgocitinib (LEO-124249/JTE052) is a selective JAK inhibitor used for reducing skin inflammation and treating chronic dermatitis.Formula:C18H24N6O2Color and Shape:SolidMolecular weight:356.43NSC 228155
CAS:NSC 228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.Formula:C11H6N4O4SPurity:99.84%Color and Shape:SolidMolecular weight:290.25Ref: TM-T6908
2mg34.00€5mg48.00€1mL*10mM (DMSO)50.00€10mg63.00€25mg117.00€50mg178.00€100mg334.00€200mg469.00€653-47
CAS:653-47 enhances the effects of 666-15 on inhibiting CREB and is a mild CREB inhibitor itself (IC50: 26.3μM).Formula:C20H19ClN2O3Color and Shape:SolidMolecular weight:370.83Aurora kinase inhibitor-3
CAS:Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK,Formula:C21H18F3N5OPurity:98.91%Color and Shape:SolidMolecular weight:413.4Ref: TM-T5524
1mg66.00€2mg89.00€5mg152.00€1mL*10mM (DMSO)167.00€10mg236.00€25mg401.00€50mg580.00€100mg797.00€200mg1,099.00€
