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Chromatin/Epigenetics

Chromatin/Epigenetics

Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.

Subcategories of "Chromatin/Epigenetics"

Found 2235 products of "Chromatin/Epigenetics"

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  • Atractylenolide I

    CAS:
    <p>Atractylenolide-I reduces inflammation, improves sepsis, liver, and kidney function, and enhances EOC cell sensitivity to paclitaxel.</p>
    Formula:C15H18O2
    Purity:97.55% - 99.92%
    Color and Shape:Solid
    Molecular weight:230.3
  • UNC1999

    CAS:
    <p>UNC1999 is a orally bioavailable, effective and specific inhibitor of EZH2 (IC50=2 nM) and EZH1 (IC50=45).</p>
    Formula:C33H43N7O2
    Purity:99.19% - >99.99%
    Color and Shape:Solid
    Molecular weight:569.74
  • GN44028

    CAS:
    <p>GN44028 is a HIF-1 inhibitor with an IC50 of 14 nM, stopping HIF-1α activity but not mRNA or protein levels, or dimerization.</p>
    Formula:C18H15N3O2
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:305.33
  • HIF-2α-IN-4

    CAS:
    <p>HIF-2a translation inhibitor is a compound used as a molecular building block.</p>
    Formula:C9H9N3O4S2
    Purity:≥98%
    Color and Shape:Solid
    Molecular weight:287.32
  • 8-CHLOROQUINAZOLIN-4(1H)-ONE

    CAS:
    <p>8-CHLOROQUINAZOLIN-4(1H)-ONE is inhibitor of Poly [ADP-ribose] polymerase 1 (human)</p>
    Formula:C8H5ClN2O
    Purity:98.79%
    Color and Shape:Solid
    Molecular weight:180.59
  • ICG001

    CAS:
    <p>ICG001 antagonizes Wnt signaling, binds CBP with 3 μM IC50, not p300.</p>
    Formula:C33H32N4O4
    Purity:99.06% - 99.95%
    Color and Shape:Solid
    Molecular weight:548.63
  • (R)-(-)-JQ1 Enantiomer

    CAS:
    <p>(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1. (+)-JQ1 is a BET bromodomain inhibitor, acting on BRD4(1/2)(IC50 of 77 nM/33 nM in a cell-free assay)</p>
    Formula:C23H25ClN4O2S
    Purity:99.38%
    Color and Shape:Solid
    Molecular weight:456.99
  • JQEZ5

    CAS:
    <p>JQEZ5 is an inhibitor of EZH2 lysine methyltransferase (IC50 = 11.1 nM).</p>
    Formula:C30H38N8O2
    Purity:98.14% - ≥98%
    Color and Shape:Solid
    Molecular weight:542.68
  • Rucaparib hydrochloride

    CAS:
    <p>Rucaparib hydrochloride (AG014699) is an oral PARP inhibitor with Ki 1.4 nM for PARP1 and hinders H6PD, studied in CRPC research.</p>
    Formula:C19H19ClFN3O
    Color and Shape:Solid
    Molecular weight:359.83
  • XMD8-92

    CAS:
    <p>XMD8-92 is an effective and specific BMK1/ERK5 inhibitor (Kd: 80 nM).</p>
    Formula:C26H30N6O3
    Purity:98.21%
    Color and Shape:Solid
    Molecular weight:474.55
  • Rucaparib acetate

    CAS:
    <p>Rucaparib acetate, an oral PARP-1, -2, -3 inhibitor (Ki 1.4 nM for PARP1), also moderately inhibits H6PD; promising for CRPC research.</p>
    Formula:C21H22FN3O3
    Color and Shape:Solid
    Molecular weight:383.423
  • Menin-MLL inhibitor 20

    CAS:
    <p>Menin-MLL inhibitor 20 is an irreversible inhibitor of menin-MLL interaction with antitumor activities.</p>
    Formula:C33H40N8O4
    Purity:97.77%
    Color and Shape:Solid
    Molecular weight:612.72
  • Ethyl 3,4-dihydroxybenzoate

    CAS:
    <p>Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.</p>
    Formula:C9H10O4
    Purity:99.88%
    Color and Shape:White Crystal Or Powder
    Molecular weight:182.17
  • Ruboxistaurin

    CAS:
    <p>Ruboxistaurin (LY333531) is a selective PKC beta inhibitor, Ki 2 nM, inhibits beta I/II (IC50: 4.7/5.9 nM), orally active.</p>
    Formula:C28H28N4O3
    Color and Shape:Solid
    Molecular weight:468.55
  • EB-47 dihydrochloride

    CAS:
    <p>EB 47 is an effective inhibitor of PARP-1 (IC50: 45 nM).</p>
    Formula:C24H29Cl2N9O6
    Color and Shape:Solid
    Molecular weight:610.45
  • SC-43

    CAS:
    <p>SC-43 is a potent and orally active agonist of SHP-1 (PTPN6).</p>
    Formula:C21H13ClF3N3O2
    Purity:98.44%
    Color and Shape:Solid
    Molecular weight:431.8
  • MS31 trihydrochloride


    <p>MS31 trihydrochloride: a selective SPIN1 inhibitor, binds H3K4me3 (IC50: 77-243 nM), non-toxic to healthy cells.</p>
    Formula:C20H30Cl3N3O2
    Color and Shape:Solid
    Molecular weight:450.83
  • CPI-637

    CAS:
    <p>CPI-637 is a selective and cell-active benzodiazepinone CBP/EP300 bromodomain inhibitor.</p>
    Formula:C22H22N6O
    Purity:99.89% - 99.95%
    Color and Shape:Solid
    Molecular weight:386.45
  • SP-146


    <p>SP-146 is a selective, potent and non-ATP-competitive Aurora B inhibitor(IC50 : 0.316 nM).</p>
    Formula:C25H20FN7O
    Purity:97.82%
    Color and Shape:Solid
    Molecular weight:453.47
  • Abrocitinib

    CAS:
    <p>Abrocitinib (PF-04965842) (PF-04965842) is a potent, specific and orally-active JAK1 inhibitor (IC50s: 29/803 nM for JAK1/2).</p>
    Formula:C14H21N5O2S
    Purity:99.09% - 99.91%
    Color and Shape:Solid
    Molecular weight:323.41