
Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2235 products of "Chromatin/Epigenetics"
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Atractylenolide I
CAS:<p>Atractylenolide-I reduces inflammation, improves sepsis, liver, and kidney function, and enhances EOC cell sensitivity to paclitaxel.</p>Formula:C15H18O2Purity:97.55% - 99.92%Color and Shape:SolidMolecular weight:230.3UNC1999
CAS:<p>UNC1999 is a orally bioavailable, effective and specific inhibitor of EZH2 (IC50=2 nM) and EZH1 (IC50=45).</p>Formula:C33H43N7O2Purity:99.19% - >99.99%Color and Shape:SolidMolecular weight:569.74GN44028
CAS:<p>GN44028 is a HIF-1 inhibitor with an IC50 of 14 nM, stopping HIF-1α activity but not mRNA or protein levels, or dimerization.</p>Formula:C18H15N3O2Purity:99.52%Color and Shape:SolidMolecular weight:305.33HIF-2α-IN-4
CAS:<p>HIF-2a translation inhibitor is a compound used as a molecular building block.</p>Formula:C9H9N3O4S2Purity:≥98%Color and Shape:SolidMolecular weight:287.328-CHLOROQUINAZOLIN-4(1H)-ONE
CAS:<p>8-CHLOROQUINAZOLIN-4(1H)-ONE is inhibitor of Poly [ADP-ribose] polymerase 1 (human)</p>Formula:C8H5ClN2OPurity:98.79%Color and Shape:SolidMolecular weight:180.59ICG001
CAS:<p>ICG001 antagonizes Wnt signaling, binds CBP with 3 μM IC50, not p300.</p>Formula:C33H32N4O4Purity:99.06% - 99.95%Color and Shape:SolidMolecular weight:548.63(R)-(-)-JQ1 Enantiomer
CAS:<p>(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1. (+)-JQ1 is a BET bromodomain inhibitor, acting on BRD4(1/2)(IC50 of 77 nM/33 nM in a cell-free assay)</p>Formula:C23H25ClN4O2SPurity:99.38%Color and Shape:SolidMolecular weight:456.99JQEZ5
CAS:<p>JQEZ5 is an inhibitor of EZH2 lysine methyltransferase (IC50 = 11.1 nM).</p>Formula:C30H38N8O2Purity:98.14% - ≥98%Color and Shape:SolidMolecular weight:542.68Rucaparib hydrochloride
CAS:<p>Rucaparib hydrochloride (AG014699) is an oral PARP inhibitor with Ki 1.4 nM for PARP1 and hinders H6PD, studied in CRPC research.</p>Formula:C19H19ClFN3OColor and Shape:SolidMolecular weight:359.83XMD8-92
CAS:<p>XMD8-92 is an effective and specific BMK1/ERK5 inhibitor (Kd: 80 nM).</p>Formula:C26H30N6O3Purity:98.21%Color and Shape:SolidMolecular weight:474.55Rucaparib acetate
CAS:<p>Rucaparib acetate, an oral PARP-1, -2, -3 inhibitor (Ki 1.4 nM for PARP1), also moderately inhibits H6PD; promising for CRPC research.</p>Formula:C21H22FN3O3Color and Shape:SolidMolecular weight:383.423Menin-MLL inhibitor 20
CAS:<p>Menin-MLL inhibitor 20 is an irreversible inhibitor of menin-MLL interaction with antitumor activities.</p>Formula:C33H40N8O4Purity:97.77%Color and Shape:SolidMolecular weight:612.72Ethyl 3,4-dihydroxybenzoate
CAS:<p>Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.</p>Formula:C9H10O4Purity:99.88%Color and Shape:White Crystal Or PowderMolecular weight:182.17Ruboxistaurin
CAS:<p>Ruboxistaurin (LY333531) is a selective PKC beta inhibitor, Ki 2 nM, inhibits beta I/II (IC50: 4.7/5.9 nM), orally active.</p>Formula:C28H28N4O3Color and Shape:SolidMolecular weight:468.55EB-47 dihydrochloride
CAS:<p>EB 47 is an effective inhibitor of PARP-1 (IC50: 45 nM).</p>Formula:C24H29Cl2N9O6Color and Shape:SolidMolecular weight:610.45SC-43
CAS:<p>SC-43 is a potent and orally active agonist of SHP-1 (PTPN6).</p>Formula:C21H13ClF3N3O2Purity:98.44%Color and Shape:SolidMolecular weight:431.8MS31 trihydrochloride
<p>MS31 trihydrochloride: a selective SPIN1 inhibitor, binds H3K4me3 (IC50: 77-243 nM), non-toxic to healthy cells.</p>Formula:C20H30Cl3N3O2Color and Shape:SolidMolecular weight:450.83CPI-637
CAS:<p>CPI-637 is a selective and cell-active benzodiazepinone CBP/EP300 bromodomain inhibitor.</p>Formula:C22H22N6OPurity:99.89% - 99.95%Color and Shape:SolidMolecular weight:386.45SP-146
<p>SP-146 is a selective, potent and non-ATP-competitive Aurora B inhibitor(IC50 : 0.316 nM).</p>Formula:C25H20FN7OPurity:97.82%Color and Shape:SolidMolecular weight:453.47Abrocitinib
CAS:<p>Abrocitinib (PF-04965842) (PF-04965842) is a potent, specific and orally-active JAK1 inhibitor (IC50s: 29/803 nM for JAK1/2).</p>Formula:C14H21N5O2SPurity:99.09% - 99.91%Color and Shape:SolidMolecular weight:323.41

