Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2567 products of "Chromatin/Epigenetics"
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CAY10721
CAS:CAY10721 inhibits SIRT3 (39% at 200 μM), linked to OSCC and breast cancer; lowers OSCC growth, enhances radio/chemo sensitivity.Formula:C18H13N3O3SColor and Shape:SolidMolecular weight:351.38A2AAR/HDAC-IN-1
CAS:A2AAR/HDAC-IN-1 (compound 14c) is an orally active, balanced A2AAR/HDAC dual inhibitor of A2AAR (Ki: 163.5 nM), HDAC1 (IC50: 145.3 nM). effect.Formula:C24H21N7O2Color and Shape:SolidMolecular weight:439.47CSV0C018875 Hydrochloride
CAS:CSV0C018875 Hydrochloride: Novel G9a inhibitor with low toxicity, effective in enzyme/cell assays, outperforms BIX-0129.Formula:C18H18Cl2N2OColor and Shape:SolidMolecular weight:349.255MARK-IN-4
CAS:MARK-IN-4 inhibits microtubule kinase (MARK) effectively (IC50: 1 nM), a target for Alzheimer's therapy.Formula:C21H23N7OSColor and Shape:SolidMolecular weight:421.52PARP1-IN-9
CAS:PARP1-IN-9, potent PARP1 inhibitor with 30.51 nM IC50, outperforms Olaparib in anticancer efficacy.Formula:C18H21N3O5Color and Shape:SolidMolecular weight:359.38NCDM-32B
CAS:NCDM-32B, a novel potent and selective KDM4 inhibitor, impairs viability and transforms phenotypes of basal breast cancer.Formula:C15H30N2O4Purity:98%Color and Shape:SolidMolecular weight:302.41HMS607P03
CAS:HMS607P03 is an activator of SIRT1 which induces autophagic cell death via the AMPK-mTOR-ULK complex and induces mitophagy by the SIRT1-PINK1-Parkin pathway.Formula:C26H19ClN4O3S2Color and Shape:SolidMolecular weight:535.045-Octyl-α-ketoglutarate
CAS:In addition to its role in the Krebs cycle, α-ketoglutarate (2-oxoglutarate) has roles as a substrate or modulator of enzymes.Formula:C13H22O5Color and Shape:SolidMolecular weight:258.31MAT2A-IN-6
CAS:MAT2A-IN-6 inhibits MAT2A, may slow MTAP-deficient cancer cell growth, has research value in cancer.Formula:C18H13ClF3N3O3Color and Shape:SolidMolecular weight:411.76Bizine dihydrochloride
CAS:Bizine dihydrochloride is a potent LSD1 inhibitor in vitro, being selective versus monoamine oxidases A/B and the LSD1 homologue, LSD2.Formula:C18H25Cl2N3OColor and Shape:SolidMolecular weight:370.32MZ-242
CAS:MZ-242 is an effective and selective inhibitor of Sirt2.Formula:C24H27N7O3S2Purity:98%Color and Shape:SolidMolecular weight:525.65KDOAM-25
CAS:KDOAM-25, a potent KDM5 inhibitor, enhances H3K4 methylation, hampers MM1S cell growth; IC50: 71 nM (5A), 19 nM (5B), 69 nM (5C/D).Formula:C15H25N5O2Purity:98%Color and Shape:SolidMolecular weight:307.39HDAC ligand-1
CAS:HDAC ligand-1 is a synthetic precursor utilized in the production of PROTAC-based HDAC degraders [1].Formula:C7H8N2OPurity:98%Color and Shape:SolidMolecular weight:136.15PRMT5:MEP50 PPI
PRMT5:MEP50 PPI inhibitor with anti-tumor and anti-proliferative effects on lung and prostate cancers.Formula:C24H22N4O4Color and Shape:SolidMolecular weight:430.46Aurora Kinases-IN-2
CAS:Aurora Kinases-IN-2 (12Aj) hinders Aurora A/B kinases (IC50: 90/152 nM), used in cancer studies.Formula:C22H18ClN5O3Color and Shape:SolidMolecular weight:435.86CypD inhibitor C-9
CAS:CypD inhibitor C-9 is a CypD inhibitor, it attenuates mitochondrial and cellular perturbation insulted by Aß and calcium stress.Formula:C22H22N4O4S2Color and Shape:SolidMolecular weight:470.56CAY10727
CAS:CAY10727 selectively inhibits PAD3 (15,600 M^-1min^-1) over PAD1, PAD2, and PAD4.Formula:C21H22Cl2N4O2Color and Shape:SolidMolecular weight:433.334-iodo-SAHA
CAS:4-Iodo-SAHA (1k), an oral HDAC inhibitor for cancer research, has EC50s from 0.12 to 1.3 μM across various cell lines.Formula:C14H19IN2O3Color and Shape:SolidMolecular weight:390.22JAK-IN-20
CAS:JAK-IN-20: potent oral JAK1,2,3 inhibitor with IC50s 7, 5, 14 nM respectively, good pharmacokinetics, anti-inflammatory in vivo.Formula:C28H30FN7O2Color and Shape:SolidMolecular weight:515.58NL-103
CAS:NL-103, a dual-targeting compound, inhibits HDACs & Hh pathway, countering vismodegib-resistant Smo mutations.Formula:C26H27Cl2N5O4Color and Shape:SolidMolecular weight:544.43
