Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2567 products of "Chromatin/Epigenetics"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
EPZ033294
CAS:EPZ033294 has potential anticancer and antiproliferative activity.Formula:C20H22ClN7OPurity:99.95%Color and Shape:SolidMolecular weight:411.89Peficitinib hydrochloride
CAS:Peficitinib HCl (ASP015K) is an oral JAK inhibitor with IC50s: JAK1 (3.9 nM), JAK2 (5.0 nM), JAK3 (0.7 nM), Tyk2 (4.8 nM).Formula:C18H23ClN4O2Color and Shape:SolidMolecular weight:362.86JJO-1
CAS:JJO-1 is a bi-quinoline activating all AMPK αβγ isoforms except γ3; it requires low ATP and is unaffected by γ mutations or β deletions.Formula:C19H13N3Color and Shape:SolidMolecular weight:283.33MAT2A inhibitor 3
CAS:MAT2A inhibitor 3 can be used in the cancer research.Formula:C16H14ClN3OColor and Shape:SolidMolecular weight:299.75Sirt2-IN-6
CAS:Sirt2-IN-6 is a potent and selective inhibitor of SIRT2 (IC50: 0.815 μM) and can be used to study cancer.Formula:C26H26N6O3SColor and Shape:SolidMolecular weight:502.59ZYJ-25e
CAS:ZYJ-25e is an oral histone deacetylase inhibitor (HDACi) with potent antitumor activities.Formula:C30H40N4O8Purity:98%Color and Shape:SolidMolecular weight:584.66SPV106
CAS:SPV106 is a ligand of lysine acetyltransferases (KATs).Formula:C22H40O4Purity:98%Color and Shape:SolidMolecular weight:368.55BIX-01338 hydrate
CAS:BIX-01338 hydrate is an inhibitor of histone lysine methyltransferase.Formula:C32H26F3N3O7Purity:98%Color and Shape:SolidMolecular weight:621.56HDAC3 Inhibitor
CAS:HDAC3 inhibitor: allosteric, Ki=0.16 nM, favors HDAC3 over HDAC1/2, targets specific leukemia cells, EC50=36.37-151.7 nM.Formula:C20H23N3O2Color and Shape:SolidMolecular weight:337.42DM-NOFD
CAS:DM-NOFD is a cell penetrant prodrug of NOFD, which is a potent and selective inhibitor of an asparaginyl hydroxylase FIH (factor-inhibiting HIF).Formula:C13H15NO5Color and Shape:SolidMolecular weight:265.26ZL0516
CAS:ZL0516, a chromone-based oral BRD4 BD1 inhibitor, shows potent in vivo efficacy and good pharmacokinetics, suggesting use in treating inflammation.Formula:C27H34N2O6Color and Shape:SolidMolecular weight:482.57Dot1L-IN-2
CAS:Dot1l-in-2 is an effective, selective and oral bioutilization inhibitor of histone methyltransferase Dot1L, with IC50 and Ki of 0.4 nM and 0.08 nM, respectivelyFormula:C27H24N8OPurity:98%Color and Shape:SolidMolecular weight:476.53OTS186935
CAS:OTS186935 is a inhibitor of protein methyltransferase SUV39H2(IC50 of 6.49 nM).Formula:C25H26ClN5O2Purity:98%Color and Shape:SolidMolecular weight:463.96dWIZ-1
CAS:dWIZ-1 ((rac)-dWIZ-1) is a potent WIZ molecular gel degrader tha induction of haemoglobin fetalis (HbF) in erythroblasts, sickle cell disease (SCD).Formula:C22H29N3O4Purity:92.87% - 92.87%Color and Shape:SolidMolecular weight:399.48IHCH-3064
CAS:IHCH-3064: dual-action cancer immunotherapy, A2AR affinity (Ki 2.2 nM), selective HDAC1 inhibitor (IC50 80.2 nM).Formula:C25H21N9O2Color and Shape:SolidMolecular weight:479.49CAY10722
CAS:CAY10722 is a SIRT3 inhibitor, affecting metabolism and cancer cell survival; varying impacts on esophageal and breast cancer.Formula:C21H14Cl2N2O2Color and Shape:SolidMolecular weight:397.25SRI-42127
CAS:SRI-42127 is a novel small molecule inhibitor of the RNA regulatory factor HuR that inhibits tumor growth and reduces neuropathic pain following nerve injury.Formula:C19H20N6OPurity:99.66%Color and Shape:SolidMolecular weight:348.4CTX-0124143
CAS:CTX-0124143 is a histone acetyltransferase inhibitor with an IC50 value of 1.0 μM for KAT6A.CTX-0124143 can be used to study cellular senescence.Formula:C17H13FN2O3SPurity:98.24%Color and Shape:SolidMolecular weight:344.36SAR156497
CAS:SAR156497: selective Aurora A/B/C inhibitor; IC50: 0.5 nM (A), 1 nM (B), 3 nM (C); good metabolic stability; anti-tumoral without genetic specificity.Formula:C27H24N4O4Color and Shape:SolidMolecular weight:468.5PRMT5-IN-C17
CAS:PRMT5-IN-C17 is a novel potent, selective, and cell active protein arginine methyltransferase 5 (PRMT5) inhibitor.Formula:C18H17N3O4SColor and Shape:SolidMolecular weight:371.41
