Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2442 products of "Chromatin/Epigenetics"
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(R)-UT-155
CAS:(R)-UT-155 is a selective androgen receptor degrader (SARD) ligand.Formula:C20H15F4N3O2Color and Shape:SolidMolecular weight:405.35ARTD10/PARP10-IN-1
CAS:ARTD10/PARP10-IN-1 is a PARP inhibitor that inhibits ARTD8/PARP14 and has anticancer and antitumour activity for the study of prostate cancer.Formula:C12H12N2O4Purity:99.14%Color and Shape:SolidMolecular weight:248.23KCN1
CAS:KCN1: a synthetic sulfonamide, nanomolar HIF inhibitor with preclinical anti-glioma and anti-pancreatic cancer effects.Formula:C26H27NO5SColor and Shape:SolidMolecular weight:465.56SIRT2-IN-10
CAS:SIRT2-IN-10 (Compound 12) is a potent inhibitor of SIRT2 (IC50: 1.3 μM), which can be used in the study of cancer and neurodegenerative diseases.Formula:C28H21N5OSColor and Shape:SolidMolecular weight:475.56SB-429201
CAS:SB-429201 is an effective, selective inhibitor of HDAC1.Formula:C28H24N2O3Purity:98%Color and Shape:SolidMolecular weight:436.5JAK3-IN-9
CAS:JAK3-IN-9, potent JAK3 inhibitor, IC50 of 1.7 nM, highly selective, low toxicity, orally bioavailable, shows anti-arthritis activity.Formula:C17H23N5O4SColor and Shape:SolidMolecular weight:393.46Binucleine 2
CAS:Binucleine 2: Drosophila Aurora B kinase inhibitor (Ki=0.36μM), dose-dependent, minimal effect on human/X. laevis kinases, disrupts mitosis in fly cells.Formula:C13H11ClFN5Color and Shape:SolidMolecular weight:291.71BRM/BRG1 ATP Inhibitor-3
CAS:BRM/BRG1 ATP Inhibitor-3 targets BRM/BRG1 (IC50: 10.4/19.3 nM) for cancer/BAF disorder research.Formula:C26H25N5O2S2Color and Shape:SolidMolecular weight:503.64NCGC00247743
CAS:NCGC00247743 is an inhibitor of histone lysine demethylase KDM4.Formula:C24H29N3O2Purity:98%Color and Shape:SolidMolecular weight:391.51CPI-905
CAS:CPI-905 is a potent and selective EZH2 inhibitor with IC50 value of 39.5 nM.Formula:C18H20N2O5Color and Shape:SolidMolecular weight:344.36LB-205
CAS:LB-205 is a Zn 2+ dependent pan-inhibitor of class I and class II HDACs. It also has a long half-life in vivo.Formula:C18H21N3O2SColor and Shape:SolidMolecular weight:343.44INCB16562
CAS:INCB16562: oral JAK1/2 inhibitor, halts IL-6/STAT3 in myeloma cells, boosts drug efficacy, stunts myeloma in mice.Formula:C19H11Cl2N5Color and Shape:SolidMolecular weight:380.23Guadecitabine
CAS:Guadecitabine is a second-generation DNA methyltransferases inhibitor. It is used for research on acute myeloid leukemia and myelodysplastic syndromes.Formula:C18H24N9O10PPurity:98%Color and Shape:SolidMolecular weight:557.41DM-NOFD
CAS:DM-NOFD is a cell penetrant prodrug of NOFD, which is a potent and selective inhibitor of an asparaginyl hydroxylase FIH (factor-inhibiting HIF).Formula:C13H15NO5Color and Shape:SolidMolecular weight:265.26NSD3-IN-2
CAS:NSD3-IN-2: Potent NSD3 inhibitor, IC50 17.97μM, halts NSCLC growth (H460, H1299, H1650) with anticancer effects.Formula:C17H15N5OSColor and Shape:SolidMolecular weight:337.4NSD3-IN-3
CAS:"NSD3-IN-3, a potent anticancer agent, inhibits NSD3 (IC50: 1.86 μM) and hampers H460 lung cancer cell growth."Formula:C15H17N5O2SColor and Shape:SolidMolecular weight:331.39Thi-DPPY
CAS:Thi-DPPY: Potent JAK3/BTK inhibitor (IC50: 1.38/62.4 nM), anti-proliferative, anti-inflammatory, potential in IPF research.Formula:C28H28ClN5O4SColor and Shape:SolidMolecular weight:566.07ZL0516
CAS:ZL0516, a chromone-based oral BRD4 BD1 inhibitor, shows potent in vivo efficacy and good pharmacokinetics, suggesting use in treating inflammation.Formula:C27H34N2O6Color and Shape:SolidMolecular weight:482.57NC-III-49-1
CAS:NC-III-49-1: potent BET inhibitor, binds BRD4/BRDT, inhibits cell growth, reduces c-Myc expression.Formula:C44H50N4O11S2Color and Shape:SoildMolecular weight:875.02iBRD4-BD1
CAS:iBRD4-BD1 inhibits BRD4 bromodomain selectively with 12 nM IC50, useful in inflammation and cancer research.Formula:C29H30F3N5OColor and Shape:SolidMolecular weight:521.58
