Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2440 products of "Chromatin/Epigenetics"
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TC-AC28
CAS:TC-AC28 is a novel potent and selective Brd2(2) ligand.Formula:C23H21N5O3Purity:98%Color and Shape:SolidMolecular weight:415.44Lepzacitinib
CAS:Lepzacitinib is a selective, inflammatory, small molecule JAK1/3(Janus kinase) inhibitor primarily used for the treatment of atopic dermatitis.Formula:C18H21N5O3Purity:99.85%Color and Shape:SolidMolecular weight:355.39Ref: TM-T78207
1mg52.00€5mg110.00€10mg170.00€25mg359.00€50mg533.00€100mg750.00€200mg1,064.00€1mL*10mM (DMSO)120.00€GSK2646264
CAS:<p>GSK2646264 (Compound 44) inhibits SYK (pIC50=7.1) and kinases like LCK, LRRK2; penetrates skin.</p>Formula:C24H26N2O2Color and Shape:SolidMolecular weight:374.48Antitumor agent-101
CAS:Antitumor agent-101 is a selective, covalent inhibitor targeting lysine methyltransferases G9a/GLP, demonstrating IC50 values of 8.5 nM for G9a and 5.5 nM forFormula:C26H38N6O3Purity:98%Color and Shape:SolidMolecular weight:482.62YM-08
CAS:YM-08 (Compound 7a), a brain-penetrant SIRT2 inhibitor, exhibits an IC50 of 19.9 μM. Additionally, it acts as an inhibitor of Hsp70 [1].Formula:C19H17N3OS2Purity:98%Color and Shape:SolidMolecular weight:367.49Tankyrase-IN-5
CAS:Tankyrase-IN-5 (Compound 30f), structurally related to MSC2504877, effectively inhibits tankyrase isoforms TNKS1 and TNKS2, with half-maximal inhibitoryFormula:C17H18N2O2Purity:98%Color and Shape:SolidMolecular weight:282.34KAT modulator-1
CAS:KAT modulator-1 (Compound 3), an epigenetics research tool, selectively interacts with the full-length p300 protein but not its catalytic domain [1].Formula:C20H36O2Purity:98%Color and Shape:SolidMolecular weight:308.5CBP/p300-IN-19 hydrochloride
CAS:CBP/p300-IN-19 HCl is a p300/CBP HAT inhibitor (IC50: p300 1.4 μM, CBP 2.2 μM) with antitumor properties.Formula:C30H28ClN3O3Color and Shape:SolidMolecular weight:514.02JH-131e-153
CAS:JH-131e-153, a diacylglycerol (DAG)-lactone, serves as a small molecule activator for the C1 domain of Munc13-1, exhibiting an activation hierarchy of WT>I590≈Formula:C22H38O5Color and Shape:SolidMolecular weight:382.53Bavarostat
CAS:Bavarostat: brain-penetrant HDAC6 inhibitor; IC50=60nM; >80x selective for HDAC6; modulates tubulin over histone acetylation.Formula:C20H27FN2O2Color and Shape:SolidMolecular weight:346.44CBP/p300-IN-19
CAS:CBP/p300-IN-19 inhibits p300/CBP HAT (IC50: 1.4μM), less effective on PCAF/Myst3, shows anti-tumor properties.Formula:C30H27N3O3Color and Shape:SolidMolecular weight:477.55CD235
CAS:CD235 is a structurally similar analog of CD161. CD161 is an orally bioavailable inhibitor of BET bromodomain.Formula:C26H20FN5O2Purity:98%Color and Shape:SolidMolecular weight:453.47EZH2-IN-14
CAS:EZH2-IN-14 selectively inhibits EZH2 at 12 nM IC50, has >200-fold specificity over EZH1, reducing H3K27me3 levels.Formula:C31H39N7O2Color and Shape:SolidMolecular weight:541.69KDM2A/7A-IN-1
CAS:KDM2A/7A-IN-1 is a KDM2A/7A inhibitor with potential anti-tumour activity for the study of duodenal adenomas and ossifying fibromucoid tumours.Formula:C33H38N4OPurity:99.59%Color and Shape:SolidMolecular weight:506.68Tubulin/JAK2-IN-1
CAS:Tubulin/JAK2-IN-1 (compound 7g) serves as a potent dual inhibitor targeting both Janus kinase 2 (JAK2) and microtubules, demonstrating significantFormula:C22H20N6O3Color and Shape:SolidMolecular weight:416.43ARTD3/PARP3-IN-1
CAS:ARTD3/PARP3-IN-1 is a non-selective inhibitor targeting diphtheria toxin-like ADP-ribosyltransferase 3 (ARTD3)/PARP3 [1].Formula:C17H16N4O2Color and Shape:SolidMolecular weight:308.33SJ1461
CAS:SJ1461 is a potent, orally active inhibitor of the BET family, selectively targeting and inhibiting BRD2 (BD1), BRD2 (BD2), BRD4 (BD1), and BRD4 (BD2) withFormula:C21H18ClN7OS2Purity:98%Color and Shape:SolidMolecular weight:484CARM1-IN-3
CAS:CARM1-IN-3 (compound 17b) is a potent, selective inhibitor of co-activator associated arginine methyltransferase (CARM1), exhibiting IC50 values of 0.07 µM forFormula:C24H32N4O2Purity:98%Color and Shape:SolidMolecular weight:408.54RK-0133114
RK-0133114, R-enantiomer of RK-701, is a G9a inhibitor (IC50 = 3.7 μM) for SCD research.Formula:C26H30N4O3Color and Shape:SolidMolecular weight:446.54CBP/p300-IN-15
CAS:CBP/p300-IN-15 inhibits p300 (IC50: 2.5 nM) & CBP (28 nM), affects OVCAR-3 (EC50: 0.865 μM) & A2780 cells (2.71 μM) for ovarian cancer research.Formula:C26H28N4O5Color and Shape:SolidMolecular weight:476.52
