Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2235 products of "Chromatin/Epigenetics"
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AS-85
CAS:<p>AS-85 is an ASH1L inhibitor with anti-leukemic activity that inhibits leukemic cell growth and increases cLogP.</p>Formula:C26H28F3N5O3S2Purity:98.96%Color and Shape:SolidMolecular weight:579.66DTP3
CAS:<p>DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.</p>Formula:C26H35N7O5Color and Shape:SolidMolecular weight:525.6TPOP146
CAS:<p>TPOP146 is a selective CBP/P300 benzoxazepine bromodomain inhibitor (Kd: 134 nM and 5.02 μM for CBP and BRD4).</p>Formula:C27H35N3O5Purity:98%Color and Shape:SolidMolecular weight:481.58PROTAC EZH2 Degrader-1
CAS:<p>PROTAC EZH2 Degrader-1 suppresses EZH2 methyltransferase activity with IC50 2.7 nM, serving as a potent tool in cancer research and EZH2 inhibition studies.</p>Formula:C54H67N7O8Color and Shape:SolidMolecular weight:942.15GSK778
CAS:<p>GSK778 selectively inhibits BD1 bromodomains (BRD2, BRD3, BRD4, BRDT) and impedes cell growth, causing arrest and apoptosis.</p>Formula:C30H33N5O3Purity:98.42%Color and Shape:SolidMolecular weight:511.61KDM4C-IN-1
CAS:<p>KDM4C-IN-1 is aKDM4C inhibitor withial anticancer activity.KDM4C-IN-1 inhibits the growth of HepG2 and A549 cells, and can be used for the study of leukaemia.</p>Formula:C15H14N4O3Purity:99.33%Color and Shape:SolidMolecular weight:298.3(2R)-Octyl-α-hydroxyglutarate
CAS:<p>(2R)-Octyl-α-hydroxyglutarate ((2R)-Octyl-2-HG) is a D-isomer 2-Hydroxyglutarate modified form.</p>Formula:C13H24O5Color and Shape:SolidMolecular weight:260.33SGC-iMLLT
CAS:<p>SGC-iMLLT is a potent and selective MLLT1/3-histone interactions inhibitor(IC50 = 0.26 μM),and is a first-in-class chemical probe displaying cellular target</p>Formula:C22H24N6OPurity:99.21%Color and Shape:SolidMolecular weight:388.47Itacitinib adipate
CAS:<p>Itacitinib adipate: oral JAK1 inhibitor, tested in phase II myelofibrosis trial.</p>Formula:C32H33F4N9O5Color and Shape:SolidMolecular weight:699.66TH1834
CAS:<p>TH1834 is a specific inhibitor of Tip60/KAT5 histone acetyltransferase. TH1834 induces apoptosis and DNA damage in MCF.</p>Formula:C33H40N6O3Purity:99.96%Color and Shape:SolidMolecular weight:568.71GSK2879552
CAS:<p>GSK2879552: oral, irreversible LSD1 inhibitor with potential cancer-fighting properties.</p>Formula:C23H28N2O2Purity:99.22%Color and Shape:SolidMolecular weight:364.48Boc-Lys(Ac)-AMC
CAS:<p>Boc-Lys(Ac)-AMC (Boc-L-Lys(Ac)-AMC) is a synthetic substrate coupled to an HDAC-specific fluorophore (Ex/Em = 355 nm/460 nm).</p>Formula:C23H31N3O6Purity:99.87%Color and Shape:SolidMolecular weight:445.51AZ505 ditrifluoroacetate
CAS:<p>AZ505 ditrifluoroacetate is an effective and selective SMYD2 inhibitor (IC50: 0.12 μM).</p>Formula:C33H40Cl2F6N4O8Color and Shape:SolidMolecular weight:805.59EHMT2-IN-1
CAS:<p>EHMT2-IN-1: potent EHMT inhibitor, for blood disorders/cancer research; IC50s <100 nM for EHMT1/2 peptides and cellular EHMT2.</p>Formula:C18H23N7OColor and Shape:SolidMolecular weight:353.42JET-209
<p>JET-209 is a potent proteolysis-targeting chimera (PROTAC) that effectively degrades CBP/p300, exhibiting half-maximal degradation concentration (DC50) values</p>Formula:C46H47N9O6Purity:98%Color and Shape:SolidMolecular weight:821.92GSK-J2
CAS:<p>GSK-J2 is an inactive enantiomer of GSK-J1 that is lipophilic and serves as an inactive control for GSK-J21.</p>Formula:C22H23N5O2Purity:97.55%Color and Shape:SolidMolecular weight:389.45Pim-1/2 kinase inhibitor 1
CAS:<p>Orally active Pim-1/2 inhibitor blocks kinase phosphorylation; used in prostate cancer research.</p>Formula:C11H9NO3SPurity:99.78%Color and Shape:SolidMolecular weight:235.26GSK9311
CAS:<p>GSK9311 inhibits BRPF bromodomain (pIC50: 6.0 and 4.3 for BRPF1 and BRPF2, respectively).</p>Formula:C24H31N5O3Purity:98%Color and Shape:SolidMolecular weight:437.53N-Descyclopropanecarbaldehyde Olaparib
CAS:<p>N-Descyclopropanecarbaldehyde Olaparib is a CRBN ligand for dual EGFR/PARP PROTAC, suitable for F-18 radiolabeling and tumor imaging via PET.</p>Formula:C20H19FN4O2Color and Shape:SolidMolecular weight:366.39INO-1001
CAS:<p>INO-1001: potent PARP inhibitor with antitumor properties, enhances radiosensitivity & radiation-induced cell death.</p>Formula:C23H25N3O4SColor and Shape:SolidMolecular weight:439.53CHZ868
CAS:<p>CHZ868 is a type II JAK inhibitor with potential antitumor activity that reverses the persistence of type I JAK inhibitors and can be used to study leukemia.</p>Formula:C22H19F2N5O2Purity:99.38%Color and Shape:SolidMolecular weight:423.42ADTL-SA1215
CAS:<p>ADTL-SA1215 is a SIRT3 activator with SIRT3 deacetylase activity for the study of triple negative breast cancer.</p>Formula:C26H29I2NO3Purity:99.23%Color and Shape:SolidMolecular weight:657.32(±)-1,2-Diolein
CAS:<p>(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein could increases myotubes Ca 2+ influx.</p>Formula:C39H72O5Color and Shape:SolidMolecular weight:620.992'-Deoxy-2'-fluoro-β-D-arabinocytidine hydrochloride
CAS:<p>2'-Deoxy-2'-fluoro-beta-D-arabinocytidine HCl inhibits DNA methyltransferase with potential anti-tumor properties.</p>Formula:C9H13ClFN3O4Purity:99.69%Color and Shape:SolidMolecular weight:281.67MS8511 hydrochloride
CAS:<p>MS8511 hydrochloride is a selective G9a/GLP inhibitor with IC50 values of 100 nM and 140 nM respectively, exhibiting covalent and irreversible characteristics.</p>Formula:C28H42ClN5O3Color and Shape:SolidMolecular weight:532.12Fenbendazole-d3
CAS:<p>Fenbendazole-d3 is a deuterated compound of Fenbendazole. Fenbendazole has a CAS number of 43210-67-9. Fenbendazole is an antinematodal benzimidazole used in veterinary medicine.</p>Formula:C15H10D3N3O2SColor and Shape:SolidMolecular weight:302.37(R)-GSK-3685032
CAS:<p>(R)-GSK-3685032 is a selective, reversible DNMT1 inhibitor, non-covalent, IC50: 0.036 μM; reduces DNA methylation, inhibits cancer growth.</p>Formula:C22H24N6OSColor and Shape:SolidMolecular weight:420.54Atinvicitinib
CAS:<p>Atinvicitinib, a selective JAK1 inhibitor, blocks cytokine signaling, modulating itch, allergy, and inflammatory responses, immune and therapeutic studies.</p>Formula:C16H17FN6O3Purity:99.36%Color and Shape:SolidMolecular weight:360.35CX-6258 hydrochloride hydrate
CAS:<p>CX-6258 hydrochloride hydrate is a potent and selective inhibitor of pan-Pim kinase that acts on Pim-1 (IC50: 5 nM), Pim-2 (IC50: 25 nM) and Pim-3 (IC50: 16 nM</p>Formula:C26H27Cl2N3O4Color and Shape:SolidMolecular weight:516.42Ilunocitinib
CAS:<p>Ilunocitinib is a non-selective and orally active Janus kinase (JAK) inhibitor for pruritus and atopic dermatitis caused by atopic dermatitis in dogs.</p>Formula:C17H17N7O2SPurity:99.88%Color and Shape:SolidMolecular weight:383.43O6BTG-octylglucoside
CAS:<p>O6BTG-octylglucoside is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor (IC50s: 10 nM and 32 nM in HeLa S3 cells and in vitro (cell extracts)).</p>Formula:C24H34BrN5O7SPurity:98%Color and Shape:SolidMolecular weight:616.53BAY-850
CAS:<p>BAY-850 is ainhibitor of adenosine triphosphatase family protein 2 that inhibits ovarian cancer growth and metastasis in in vitro and in vivo models.</p>Formula:C38H44ClN5O3Purity:98% - 98%Color and Shape:SolidMolecular weight:654.24DA-3003-1
CAS:<p>DA-3003-1 (NSC 663284) is a Cdc25 dual specificity phosphatase inhibitor with antitumor activity and inhibits Cdc25B2, Cdc25A, Cdc25B2, and Cdc25C.</p>Formula:C15H16ClN3O3Purity:99.27% - 99.79%Color and Shape:SolidMolecular weight:321.761,4-DPCA ethyl ester
CAS:<p>1,4-DPCA ethyl ester is a form of 1,4-DPCA modified, which has potential anticancer activity based on growth inhibition assays with the mlh1 rad18 yeast strain.</p>Formula:C15H12N2O3Purity:99.54%Color and Shape:SolidMolecular weight:268.27NSC 694621
CAS:<p>NSC 694621 is a PCAF inhibitor that forms a covalent bond with Cys574, irreversibly inhibiting its acetyltransferase activity, inhibit proliferation,anticancer.</p>Formula:C13H10N2O2SPurity:99.7%Color and Shape:SolidMolecular weight:258.3Anti-PARP1 Antibody (8I163)
<p>Anti-PARP1 Antibody (8I163) is a Mouse antibody targeting PARP1. Anti-PARP1 Antibody (8I163) can be used in IHC-P.</p>Color and Shape:Odour LiquidAnti-PARP Antibody (1W26)
<p>Anti-PARP Antibody (1W26) is a Mouse antibody targeting PARP. Anti-PARP Antibody (1W26) can be used in WB,IHC-P,IP.</p>Color and Shape:Odour LiquidAnti-PARP1 Antibody (6I459)
<p>Anti-PARP1 Antibody (6I459) is an antibody targeting PARP1. Anti-PARP1 Antibody (6I459) can be used in ELISA, IHC.</p>Color and Shape:Odour LiquidAnti-PARP1 Antibody (7A800)
<p>Anti-PARP1 Antibody (7A800) is an antibody targeting PARP1. Anti-PARP1 Antibody (7A800) can be used in ELISA, WB, IHC.</p>Color and Shape:Odour LiquidAnti-PARP1 Antibody (9E313)
<p>Anti-PARP1 Antibody (9E313) is a Mouse antibody targeting PARP1. Anti-PARP1 Antibody (9E313) can be used in IHC-P.</p>Color and Shape:Odour LiquidAnti-PARP1 Antibody (8S756)
<p>Anti-PARP1 Antibody (8S756) is an antibody targeting PARP1. Anti-PARP1 Antibody (8S756) can be used in ELISA, WB, IHC, IF, FCM.</p>Color and Shape:Odour LiquidGintemetostat
CAS:<p>Gintemetostat (KTX-1001) is a potent NSD2 inhibitor (IC50=0.001-0.01μM) for treating NSD2-dysregulated cancers.</p>Formula:C25H26F4N8O2Color and Shape:SolidMolecular weight:546.52PR5-LL-CM01
CAS:<p>PR5-LL-CM01 is a novel protein arginine methyltransferase 5 (PRMT5) inhibitor in colorectal and pancreatic cancers.</p>Formula:C23H27N7Color and Shape:SolidMolecular weight:401.51PROTAC PARP1 degrader
CAS:<p>PROTAC PARP1 degrader suppresses MDA-MB-231 cells at 10 μM, IC50: 6.12 μM in 24h.</p>Formula:C58H63Cl2N11O10Purity:98%Color and Shape:SolidMolecular weight:1145.1Ifidancitinib
CAS:<p>Ifidancitinib (ATI-50002) is a JAK kinase 1/3 inhibitor used to study autoimmune diseases.</p>Formula:C20H18FN5O3Purity:98.05%Color and Shape:SolidMolecular weight:395.39I-BET567
CAS:<p>I-BET567: potent, oral pan-BET inhibitor; pIC50s: 6.9 (BRD4 BD1), 7.2 (BD2); effective in mouse cancer and inflammation models.</p>Formula:C17H18ClN5O2Purity:99.8%Color and Shape:SolidMolecular weight:359.817-Chloro-4-(piperazin-1-yl)quinoline
CAS:<p>7-Cl-4-(piperazin-1-yl)quinolone: sirtuin inhibitor, serotonin uptake blocker, antimalarial (D10 IC50 1.18µM, K1 IC50 0.97µM).</p>Formula:C13H14ClN3Purity:99.52%Color and Shape:Light Yellow SolidMolecular weight:247.72AMI-1 free acid
CAS:<p>AMI-1: Potent reversible PRMT inhibitor; IC50: 8.8 μM (hPRMT1), 3.0 μM (yeast-Hmt1p); blocks substrate binding.</p>Formula:C21H16N2O9S2Purity:97.8%Color and Shape:SolidMolecular weight:504.49PCAF-IN-1
CAS:<p>PCAF-IN-1 is a highly selective PCAF inhibitor with potential anti-tumor, anti-inflammatory, and anti-heart disease effects.</p>Formula:C15H11ClN6Color and Shape:SolidMolecular weight:310.74KDM4-IN-3
CAS:<p>KDM4-IN-3 is a KDM4 inhibitor that is cell-permeable and kills prostate cancer cells at low micromolar concentrations.</p>Formula:C17H14N4OColor and Shape:SolidMolecular weight:290.32
