Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2612 products of "Chromatin/Epigenetics"
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O6BTG-octylglucoside
CAS:O6BTG-octylglucoside is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor (IC50s: 10 nM and 32 nM in HeLa S3 cells and in vitro (cell extracts)).Formula:C24H34BrN5O7SPurity:98%Color and Shape:SolidMolecular weight:616.53SIRT5 inhibitor 3
CAS:SIRT5 inhibitor 3 is potent and competitive by inhibiting SIRT5 deacetylation, with potential in metabolic, cancer, neurodegenerative, cardiovascular .Formula:C22H12FN3O4Purity:98%Color and Shape:SolidMolecular weight:401.35Protein kinase inhibitor H-7 dihydrochloride
CAS:Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor.Formula:C14H19Cl2N3O2SPurity:99.81%Color and Shape:White Crystalline SolidMolecular weight:364.29DA-3003-1
CAS:DA-3003-1 (NSC 663284) is a Cdc25 dual specificity phosphatase inhibitor with antitumor activity and inhibits Cdc25B2, Cdc25A, Cdc25B2, and Cdc25C.Formula:C15H16ClN3O3Purity:99.27% - 99.79%Color and Shape:SolidMolecular weight:321.76HDAC-IN-4
CAS:HDAC-IN-4 is a selective HDAC6 and HDAC10 inhibitor (pIC50s: 7.2 and 6.8 in BRET assay) with antitumoral activity.Formula:C20H21N3O2Color and Shape:SolidMolecular weight:335.4BAY-850
CAS:BAY-850 is ainhibitor of adenosine triphosphatase family protein 2 that inhibits ovarian cancer growth and metastasis in in vitro and in vivo models.Formula:C38H44ClN5O3Purity:98% - 98%Color and Shape:SolidMolecular weight:654.24(±)-1,2-Diolein
CAS:(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein could increases myotubes Ca 2+ influx.Formula:C39H72O5Color and Shape:SolidMolecular weight:620.99GSK-J2
CAS:GSK-J2 is an inactive enantiomer of GSK-J1 that is lipophilic and serves as an inactive control for GSK-J21.Formula:C22H23N5O2Purity:97.55%Color and Shape:SolidMolecular weight:389.45Ref: TM-T11476
1mg34.00€5mg71.00€10mg92.00€25mg157.00€50mg222.00€100mg329.00€200mg487.00€1mL*10mM (DMSO)101.00€Anti-PARP1 Antibody (8I163)
Anti-PARP1 Antibody (8I163) is a Mouse antibody targeting PARP1. Anti-PARP1 Antibody (8I163) can be used in IHC-P.Color and Shape:Odour LiquidAnti-PARP Antibody (1W26)
Anti-PARP Antibody (1W26) is a Mouse antibody targeting PARP. Anti-PARP Antibody (1W26) can be used in WB,IHC-P,IP.Color and Shape:Odour LiquidAnti-PARP1 Antibody (6I459)
Anti-PARP1 Antibody (6I459) is an antibody targeting PARP1. Anti-PARP1 Antibody (6I459) can be used in ELISA, IHC.Color and Shape:Odour LiquidAnti-PARP1 Antibody (7A800)
Anti-PARP1 Antibody (7A800) is an antibody targeting PARP1. Anti-PARP1 Antibody (7A800) can be used in ELISA, WB, IHC.Color and Shape:Odour LiquidAnti-PARP1 Antibody (9E313)
Anti-PARP1 Antibody (9E313) is a Mouse antibody targeting PARP1. Anti-PARP1 Antibody (9E313) can be used in IHC-P.Color and Shape:Odour LiquidNSC 694621
CAS:NSC 694621 is a PCAF inhibitor that forms a covalent bond with Cys574, irreversibly inhibiting its acetyltransferase activity, inhibit proliferation,anticancer.Formula:C13H10N2O2SPurity:99.7%Color and Shape:SolidMolecular weight:258.3Anti-PARP1 Antibody (8S756)
Anti-PARP1 Antibody (8S756) is an antibody targeting PARP1. Anti-PARP1 Antibody (8S756) can be used in ELISA, WB, IHC, IF, FCM.Color and Shape:Odour LiquidGintemetostat
CAS:Gintemetostat (KTX-1001) is a potent NSD2 inhibitor (IC50=0.001-0.01μM) for treating NSD2-dysregulated cancers.Formula:C25H26F4N8O2Color and Shape:SolidMolecular weight:546.52CHZ868
CAS:CHZ868 is a type II JAK inhibitor with potential antitumor activity that reverses the persistence of type I JAK inhibitors and can be used to study leukemia.Formula:C22H19F2N5O2Purity:99.38%Color and Shape:SolidMolecular weight:423.42Ilunocitinib
CAS:Ilunocitinib is a non-selective and orally active Janus kinase (JAK) inhibitor for pruritus and atopic dermatitis caused by atopic dermatitis in dogs.Formula:C17H17N7O2SPurity:99.88%Color and Shape:SolidMolecular weight:383.43Ref: TM-T38571
1mg92.00€5mg230.00€10mg356.00€25mg713.00€50mg1,189.00€100mg1,791.00€200mg2,412.00€1mL*10mM (DMSO)251.00€7-Chloro-4-(piperazin-1-yl)quinoline
CAS:7-Cl-4-(piperazin-1-yl)quinolone: sirtuin inhibitor, serotonin uptake blocker, antimalarial (D10 IC50 1.18µM, K1 IC50 0.97µM).Formula:C13H14ClN3Purity:99.52%Color and Shape:Light Yellow SolidMolecular weight:247.72SIRT-IN-3
CAS:SIRT-IN-3: potent SIRT1 inhibitor (IC50=17μM), 4x selective over SIRT2, 14x over SIRT3 (IC50s: 74μM & 235μM).Formula:C13H12N2OColor and Shape:SolidMolecular weight:212.25Fenbendazole-d3
CAS:Fenbendazole-d3 is a deuterated compound of Fenbendazole. Fenbendazole has a CAS number of 43210-67-9. Fenbendazole is an antinematodal benzimidazole used in veterinary medicine.Formula:C15H10D3N3O2SColor and Shape:SolidMolecular weight:302.37AMI-1 free acid
CAS:AMI-1: Potent reversible PRMT inhibitor; IC50: 8.8 μM (hPRMT1), 3.0 μM (yeast-Hmt1p); blocks substrate binding.
Formula:C21H16N2O9S2Purity:97.8%Color and Shape:SolidMolecular weight:504.49XY1
CAS:XY1 is a very close analogue of SGC707 (a potent, selective, and non-competitive inhibitor of PRMT3 with IC50 of 31 nM), It is intended to be used as aFormula:C17H19N3O2Purity:97.74% - 99%Color and Shape:SolidMolecular weight:297.35AZ960
CAS:AZ960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: <3 nM and0.45 nM).Formula:C18H16F2N6Purity:96.02% - 99.88%Color and Shape:SolidMolecular weight:354.36ASP4132
CAS:ASP4132 is an orally active AMPK activator (EC50 : 18 nM), has anti-cancer activity.Formula:C46H51F3N6O8S2Purity:98.34%Color and Shape:SolidMolecular weight:937.06Ref: TM-T8432
1mg50.00€5mg114.00€10mg177.00€25mg321.00€50mg482.00€100mg677.00€200mg928.00€1mL*10mM (DMSO)185.00€4-(3-Chlorophenyl)-2(3H)-thiazolone
CAS:4-(3-chlorophenyl)-2,3-dihydro-1,3-thiazol-2-one: a thiazole used to make antifungals, antivirals, and anti-inflammatories.Formula:C9H6ClNOSPurity:95.311%Color and Shape:SolidMolecular weight:211.67UNC0379
CAS:UNC0379 is a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8.Formula:C23H35N5O2Purity:94.41% - 99.97%Color and Shape:SolidMolecular weight:413.56WP1066
CAS:WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3.Formula:C17H14BrN3OPurity:98.92% - 99.73%Color and Shape:SolidMolecular weight:356.22BI-7273
CAS:BI-7273 is an effective, specific, BRD9 BD Inhibitor, which can infiltrate cell.Formula:C20H23N3O3Purity:97.37% - 99.57%Color and Shape:SolidMolecular weight:353.41TCS PIM-1 1
CAS:TCS PIM-1 1 (SC 204330) is a potent ATP-competitive inhibitor of Pim-1 kinase with an IC50 of 50 nM, selective over MEK1/2 and Pim-2.Formula:C18H11BrN2O2Purity:97% - 97.98%Color and Shape:SolidMolecular weight:367.2Ref: TM-T2253
1mg34.00€5mg60.00€10mg94.00€25mg177.00€50mg269.00€100mg401.00€200mg580.00€1mL*10mM (DMSO)92.00€Rucaparib monocamsylate
CAS:Rucaparib monocamsylate (Rucaparib Camsylate) is a PARP inhibitor. Rucaparib Camsylate also displays binding affinity to eight other PARP domains.
Formula:C29H34FN3O5SPurity:99.82%Color and Shape:SolidMolecular weight:555.66PI-1840
CAS:PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.Formula:C22H26N4O3Purity:98.82%Color and Shape:SolidMolecular weight:394.473-methyl-1,2-dihydroquinolin-2-one
CAS:3-methyl-1,2-dihydroquinolin-2-one is the first known micromolar inhibitors of the ATAD2 bromodomain.Formula:C10H9NOPurity:99.62%Color and Shape:SolidMolecular weight:159.18Ref: TM-T50035
1mg35.00€5mg77.00€10mg103.00€25mg170.00€50mg250.00€100mg354.00€200mg480.00€1mL*10mM (DMSO)62.00€PF-06409577
CAS:PF-06409577 is an effective, orally active, and specific allosteric activator of AMPK (EC50: 7 nM, for α1β1γ1).Formula:C19H16ClNO3Purity:95.17% - 98.21%Color and Shape:SolidMolecular weight:341.79Ref: TM-T4427
1mg34.00€2mg43.00€5mg63.00€10mg100.00€25mg200.00€50mg334.00€100mg537.00€200mg762.00€1mL*10mM (DMSO)71.00€NSC 228155
CAS:NSC 228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.Formula:C11H6N4O4SPurity:99.84%Color and Shape:SolidMolecular weight:290.25Ref: TM-T6908
2mg34.00€5mg48.00€10mg63.00€25mg117.00€50mg178.00€100mg334.00€200mg469.00€1mL*10mM (DMSO)50.00€653-47
CAS:653-47 enhances the effects of 666-15 on inhibiting CREB and is a mild CREB inhibitor itself (IC50: 26.3μM).Formula:C20H19ClN2O3Color and Shape:SolidMolecular weight:370.83Aurora kinase inhibitor-3
CAS:Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK,Formula:C21H18F3N5OPurity:98.91%Color and Shape:SolidMolecular weight:413.4Ref: TM-T5524
1mg70.00€2mg95.00€5mg160.00€10mg250.00€25mg424.00€50mg612.00€100mg842.00€200mg1,159.00€1mL*10mM (DMSO)170.00€BEBT-908
CAS:BEBT-908 (PI3Kα inhibitor 1) is a selective PI3Kα inhibitor (IC50 <0.1 μM). BEBT-908 also inhibits HDAC (0.1 μM≤IC50≤1 μM).Formula:C23H25N9O3SPurity:99.67%Color and Shape:SolidMolecular weight:507.57Ref: TM-T16529
1mg94.00€5mg222.00€10mg334.00€25mg562.00€50mg802.00€100mg1,063.00€200mg1,459.00€1mL*10mM (DMSO)249.00€PF-CBP1
CAS:PF-CBP1 HCl is a highly selective inhibitor of the bromodomain of CREB-binding protein(CREBBP).Formula:C29H36N4O3Purity:99.45%Color and Shape:SolidMolecular weight:488.62Ritlecitinib
CAS:Ritlecitinib (PF-06651600) is an orally available, selective JAK3 inhibitor and does not affect the activity of JAK1/2.Cost-effective and quality-assured.Formula:C15H19N5OPurity:98.82% - 99.92%Color and Shape:SolidMolecular weight:285.34Ref: TM-T5382
2mg37.00€5mg52.00€10mg90.00€25mg205.00€50mg290.00€100mg408.00€200mg595.00€1mL*10mM (DMSO)73.00€6-Bromo-3-methyl-1,4-dihydroquinazolin-2-one
CAS:CHEMBRDG-BB 7118966 is an inhibitor of Bromodomain-containing protein 4 (human).Formula:C9H9BrN2OPurity:99.28%Color and Shape:SolidMolecular weight:241.08Ref: TM-T8609
1mg58.00€5mg116.00€10mg172.00€25mg281.00€50mg396.00€100mg537.00€200mg712.00€1mL*10mM (DMSO)107.00€Delgocitinib EtOH
CAS:Delgocitinib (LEO-124249/JTE052) is a selective JAK inhibitor used for reducing skin inflammation and treating chronic dermatitis.Formula:C18H24N6O2Color and Shape:SolidMolecular weight:356.43Paris saponin VII
CAS:Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.Formula:C51H82O21Purity:99.51% - 99.63%Color and Shape:SolidMolecular weight:1031.18O-304
CAS:O-304 is a pan-activator of AMP-activated protein kinase (AMPK).Formula:C16H11Cl2N3O2SPurity:99.84% - ≥98%Color and Shape:SolidMolecular weight:380.25Ref: TM-T7362
1mg63.00€2mg92.00€5mg137.00€10mg205.00€25mg409.00€50mg605.00€100mg860.00€500mg1,728.00€1mL*10mM (DMSO)150.00€ZINC13466751
CAS:ZINC13466751 is a potent HIF-1α/von Hippel-Lindau interaction inhibitor(IC50 = 2.0 µM).Formula:C20H21N5O2Purity:99.8%Color and Shape:SolidMolecular weight:363.41UNC1079
CAS:UNC1079 is an selective L3MBTL3 domain inhibitor
Formula:C28H42N4O2Purity:99.48%Color and Shape:SolidMolecular weight:466.66Senaparib
CAS:Senaparib (IMP4297) is a novel highly potent and selective oral PARP1/2 inhibitor with strong antitumor activity.Formula:C24H20F2N6O3Purity:99.8%Color and Shape:SolidMolecular weight:478.45Ref: TM-T9593
1mg46.00€2mg59.00€5mg87.00€10mg153.00€25mg274.00€50mg432.00€100mg638.00€1mL*10mM (DMSO)96.00€TP-064
CAS:TP-064: Potent, selective PRMT4 inhibitor, IC50 < 10nM for H3 methylation, 100x selectivity, blocks MED12 methylation at 43nM.Formula:C28H34N4O2Purity:97.85%Color and Shape:SolidMolecular weight:458.6Ref: TM-T28996
1mg35.00€2mg50.00€5mg74.00€10mg113.00€25mg231.00€50mg462.00€100mg673.00€1mL*10mM (DMSO)75.00€4-Phenylbutyric acid
CAS:4-Phenylbutyric acid (Benzenebutyric acid) is a HDAC inhibitor and an endoplasmic reticulum stress (ERS) inhibitor. Cost-effective and quality-assured.Formula:C10H12O2Purity:98.40% - 99.76%Color and Shape:SolidMolecular weight:164.2KDM4D-IN-1
CAS:KDM4D-IN-1 is a KDM4D inhibitor (IC50: 0.41±0.03 μM).Formula:C11H7N5OPurity:99.51% - >99.99%Color and Shape:SolidMolecular weight:225.21Ref: TM-T4214
1mg73.00€5mg158.00€10mg245.00€25mg495.00€50mg795.00€100mg1,161.00€1mL*10mM (DMSO)168.00€
