Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2611 products of "Chromatin/Epigenetics"
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EML741
CAS:EML741 also inhibits DNMT1 (IC50, 3.1 μM), with no effect on DNMT3a or DNMT3b.Formula:C31H49N5O2Purity:98%Color and Shape:SolidMolecular weight:523.75YUKA1
CAS:YUKA1, a cell-permeable KDM5A inhibitor with a weak effect on KDM5C, increase H3K4me3 and inhibit the proliferation, prevent drug-resistant.Formula:C13H16N4O2SPurity:99.85%Color and Shape:SolidMolecular weight:292.36Ref: TM-T17278
1mg105.00€5mg250.00€10mg409.00€25mg802.00€50mg1,224.00€100mg1,783.00€200mg2,457.00€1mL*10mM (DMSO)268.00€Setin-1
CAS:Setin-1 is the most potent Set7 inhibitor that acts by inhibiting the KMTase G9a.Formula:C29H21F3N2O2Purity:98%Color and Shape:SolidMolecular weight:486.48GSK 525768A
CAS:GSK 525768A, the inactive enantiomer of GSK525762A, exhibits no activity towards BET.Formula:C22H22ClN5O2Color and Shape:SolidMolecular weight:423.9OXFBD03
CAS:OXFBD03 is the bromodomain and extra terminal domain bromodomain family member BRD4(1) inhibitor.Formula:C20H19NO4Purity:98%Color and Shape:SolidMolecular weight:337.37LY 170198
CAS:LY 170198 is a protein kinase C inhibitor.Formula:C22H25N5O5Purity:98%Color and Shape:SolidMolecular weight:439.46DHPCC-9
CAS:DHPCC-9 is an inhibitor of Pim kinase.Formula:C15H10N2OColor and Shape:SolidMolecular weight:234.25DC_501
CAS:DC_501 is a selective non-nucleoside DNA methyltransferase 1 inhibitor.Formula:C25H23Cl2N3OPurity:98%Color and Shape:SolidMolecular weight:452.38BI-9321
CAS:BI-9321: Selective NSD3-PWWP1 antagonist, Kd 166 nM. Inactive against NSD2-PWWP1/NSD3-PWWP2.Formula:C22H21FN4Purity:98%Color and Shape:SolidMolecular weight:360.43DCE_254
CAS:DCE_254 is a novel EZH2 inhibitor, it also displays significant anti-proliferation activity against lymphoma cell lines.Formula:C21H17N9OSPurity:98%Color and Shape:SolidMolecular weight:443.48Langkamide
CAS:Langkamide is a HIF-2 inhibitor with EC₅₀ values of 14.0 uM.Formula:C16H17NO5Purity:98%Color and Shape:SolidMolecular weight:303.31Aurora kinase inhibitor-10
CAS:Aurora kinase inhibitor-10 is an orally active Aurora B inhibitor (IC50: 8 nM) that exhibits antitumour effects.Formula:C21H19F5N6O4SColor and Shape:SolidMolecular weight:546.47BF1
CAS:BF1 is an inhibitor of HAT (histone acetyltransferase) active both in vitro and in vivo.Formula:C12H12ClN3SColor and Shape:SolidMolecular weight:265.76Farnesylthiotriazole
CAS:Farnesylthiotriazole is a persistent PKC activator agent.Formula:C17H27N3SPurity:98%Color and Shape:SolidMolecular weight:305.48Tenovin-D3
CAS:Tenovin-D3 is a sirtuin SirT2 inhibitor. It acts by increasing p21 (CDKN1A) expression in a p53-independent manner.Formula:C22H27Cl3N4O3SPurity:98%Color and Shape:SolidMolecular weight:533.9ML399
CAS:ML399 inhibits menin–MLL interaction, selectively blocking oncogenic MLL signaling in leukemia cells, supporting functional genomics and therapeutic research.Formula:C27H28FN3O2Purity:97.84% - 98.20%Color and Shape:SolidMolecular weight:445.53HIF-IN-33
CAS:HIF-IN-33 is an inhibitor of HIF pathway.Formula:C21H17F3N4O2Purity:98%Color and Shape:SolidMolecular weight:414.38SIRT5 inhibitor 4
CAS:SIRT5 inhibitor 4 (compound 11) is a dose-dependent and selective SIRT5 (Sirtuin5) inhibitorand no inhibitory effect on SIRT1/2/3,anticancer.Formula:C18H15N3O4SPurity:99.97%Color and Shape:SolidMolecular weight:369.39BET-BAY 002
CAS:BET-BAY 002 is an effective BET bromodomain inhibitor demonstrating efficacy in vivo and in vitro against multiple myeloma and leukaemia models.Formula:C22H18ClN5OColor and Shape:SolidMolecular weight:403.86Fagaronine chloride
CAS:Fagaronine chloride is a potent inhibitor of Topoisomerases I.Formula:C21H20ClNO4Color and Shape:SolidMolecular weight:385.84MT477
CAS:MT477 inhibits PKC-α, impairs Ras/ERK1/2 phosphorylation, induces apoptosis, and reduces proliferation in various cancer cells.Formula:C31H30N2O12S3Color and Shape:SolidMolecular weight:718.77Lobelane Hydrochloride
CAS:Lobelane Hydrochloride is a vesicular monoamine transporter-2 (VMAT2) inhibitor.Formula:C22H30ClNColor and Shape:SolidMolecular weight:343.93KF 13218
CAS:KF 13218 is a selective, potent and long lasting thromboxane B2 (TXB2) synthase inhibitor with an IC50 value of 5.3±1.3 nM.Formula:C20H20N2O3Purity:98%Color and Shape:SolidMolecular weight:336.38SirReal-1
CAS:SirReal-1 is an effective and selective inhibitor of Sirt2.Formula:C18H18N4OS2Purity:98%Color and Shape:SolidMolecular weight:370.49Prospasmine
CAS:Prospasmine is an anticholinergic.Formula:C17H28ClNO2Purity:98%Color and Shape:SolidMolecular weight:313.87Y06036
CAS:Y06036, a potent and selective BET inhibitor, can bind to the BRD4(1) bromodomain (Kd: 82 nM).Formula:C16H15BrN2O5SPurity:99.97%Color and Shape:SolidMolecular weight:427.27Hns 32
CAS:Hns 32 possesses antiarrhythmic properties in dog and guinea pig hearts. It also has vasodilator action.Formula:C24H29N3Purity:98%Color and Shape:SolidMolecular weight:359.51Rucaparib camsylate
CAS:Rucaparib camsylate, a PARP-1, -2, -3 inhibitor (Ki=1.4 nM for PARP-1) & H6PD blocker, may treat resistant prostate cancer.Formula:C19H18FN3O·xC10H16O4SColor and Shape:SolidHIF-PHD-IN-2
CAS:HIF-PHD-IN-2 (compound 25) is a highly effective PHD inhibitor, displaying IC50 values below 100 nM for PHD1, PHD2, and PHD3 [1].Formula:C17H15N5O3SColor and Shape:SolidMolecular weight:369.4WD2000-012547
CAS:WD2000-012547 is a selective inhibitor of poly(ADP-ribose)-polymerase (PARP-1) (pKi: 8.221).Formula:C17H14N2OPurity:98%Color and Shape:SolidMolecular weight:262.31Y08284
CAS:Y08284: selective CBP bromodomain inhibitor, IC50: 4.21 nM, oral. Halts prostate cancer cell growth; anti-tumor.Formula:C26H25FN4O4Color and Shape:SolidMolecular weight:476.5LSD1-IN-13
CAS:LSD1-IN-13, an oral LSD1 blocker (IC50: 24.43 nM), boosts CD86 (EC50: 470 nM), and triggers AML cell line differentiation.Formula:C23H29N3O2SColor and Shape:SolidMolecular weight:411.56TUL01101
CAS:TUL01101, a selective oral JAK1 inhibitor (IC50: 3 nM), also targets JAK2, JAK3, TYK2; for rheumatoid arthritis research.Formula:C22H25F2N5O2Color and Shape:SolidMolecular weight:429.46GSK926
CAS:GSK926 is a selective, SAM-competitive, and cell-active EZH2 inhibitor.Formula:C29H35N7O2Color and Shape:SolidMolecular weight:513.63CREBBP-IN-9
CAS:CREBBP-IN-9, a CREBBP inhibitor, acts on the bromodomain of the protein.Formula:C16H15N5O2SPurity:98%Color and Shape:SolidMolecular weight:341.39Bizine
CAS:Bizine, a Phenelzine analogue, selectively inhibits LSD1 (Ki=59 nM), modulates histone methylation in cancer, and may have neuroprotective uses.Formula:C18H23N3OColor and Shape:SolidMolecular weight:297.39M133
CAS:M133 is a selective histone deacetylase HDAC1 and HDAC2 inhibitor and potent antitumor agent.Formula:C23H24N4OS2Color and Shape:SolidMolecular weight:436.59Peficitinib hydrobromide
CAS:Peficitinib hydrobromide is used in the treatment of Psoriasis and Rheumatoid Arthritis.Formula:C18H23BrN4O2Color and Shape:SolidMolecular weight:407.312H8-A5
CAS:H8-A5, a HDAC8 inhibitor, shows antiproliferation activity in MDA-MB-231 cancer cells.Formula:C14H9F3N2O2SPurity:98%Color and Shape:SolidMolecular weight:326.29TAK-418
CAS:TAK-418 is an orally active LSD1/KDM1A inhibitor with a 2.9 nM IC50, potential for autism therapy.Formula:C17H25ClN2O2SPurity:99.69%Color and Shape:SolidMolecular weight:356.91Ref: TM-T39252
1mg131.00€5mg313.00€10mg494.00€25mg1,009.00€50mg1,359.00€100mg1,818.00€200mg2,457.00€1mL*10mM (DMSO)366.00€Arazine
CAS:Arazine, a cell-permeable G protein modulator, is an isoprenylcysteine methyltransferase substrate.Formula:C20H33NO3SPurity:90%Color and Shape:SolidMolecular weight:367.55Thi-DPPY
CAS:Thi-DPPY: Potent JAK3/BTK inhibitor (IC50: 1.38/62.4 nM), anti-proliferative, anti-inflammatory, potential in IPF research.Formula:C28H28ClN5O4SColor and Shape:SolidMolecular weight:566.07JAK3-IN-1
CAS:JAK3-IN-1 is an orally active, selective and potent JAK3 inhibitor for the study of immune system disorders.Formula:C26H30ClN7O2Color and Shape:SolidMolecular weight:508.02MS453
CAS:MS453 is a potent and selective SETD8 inhibitor with an IC50 value of 804 nM.Formula:C20H27N5O3Color and Shape:SolidMolecular weight:385.46HIF-1/2α-IN-2
CAS:HIF-1/2α-IN-2 is a potent inhibitor of HIF-1/2α, which effectively reduces the levels of HIF-1/2α.Formula:C16H11FN4O2SColor and Shape:SolidMolecular weight:342.35PI3K/Akt/CREB activator 1
CAS:PI3K/Akt/CREB activator 1 (AE-18) is an iNOS inhibitor that can be used to study vascular dementia and Parkinson's.Formula:C19H15F4NO3Color and Shape:SolidMolecular weight:381.32SIRT2-IN-11
CAS:SIRT2-IN-11 (AEM1), a SIRT2 inhibitor (IC50 18.5μM), induces apoptosis and affects p53, used in cancer research.Formula:C21H22N2OColor and Shape:SolidMolecular weight:318.41PRMT5:MEP50 PPI
PRMT5:MEP50 PPI inhibitor with anti-tumor and anti-proliferative effects on lung and prostate cancers.Formula:C24H22N4O4Color and Shape:SolidMolecular weight:430.46HPCG
CAS:HPCG is an inhibitor of HIF-1α prolyl hydroxylase.Formula:C8H8N2O4Color and Shape:SolidMolecular weight:196.16HAT-IN-1
CAS:HAT-IN-1 is an inhibitor of HAT used in the research of cancer.Formula:C23H18BrF4N3O4Purity:98%Color and Shape:SolidMolecular weight:556.3
