Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2235 products of "Chromatin/Epigenetics"
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HIF-IN-33
CAS:<p>HIF-IN-33 is an inhibitor of HIF pathway.</p>Formula:C21H17F3N4O2Purity:98%Color and Shape:SolidMolecular weight:414.38CPI-905
CAS:<p>CPI-905 is a potent and selective EZH2 inhibitor with IC50 value of 39.5 nM.</p>Formula:C18H20N2O5Color and Shape:SolidMolecular weight:344.36BET-BAY 002
CAS:<p>BET-BAY 002 is an effective BET bromodomain inhibitor demonstrating efficacy in vivo and in vitro against multiple myeloma and leukaemia models.</p>Formula:C22H18ClN5OColor and Shape:SolidMolecular weight:403.86Fagaronine chloride
CAS:<p>Fagaronine chloride is a potent inhibitor of Topoisomerases I.</p>Formula:C21H20ClNO4Color and Shape:SolidMolecular weight:385.84HDAC6-IN-5
CAS:<p>HDAC6-IN-5 (11b), potent HDAC6 blocker, crosses BBB, IC50: 0.025μM, hinders Aβ1-42/AChE aggregation, boosts neurites, low toxicity.</p>Formula:C20H14BrN3O2Color and Shape:SolidMolecular weight:408.25Lobelane Hydrochloride
CAS:<p>Lobelane Hydrochloride is a vesicular monoamine transporter-2 (VMAT2) inhibitor.</p>Formula:C22H30ClNColor and Shape:SolidMolecular weight:343.93TP-238
CAS:<p>"TP-238: Potent CECR2/BPTF dual probe; IC50: 30 nM/350 nM. Inhibits BRD9 (pIC50: 5.9); minimal activity on 338 other kinases."</p>Formula:C22H30N6O3SColor and Shape:SolidMolecular weight:458.58CTPB
CAS:<p>CTPB is a potent p300 histone acetyltransferase (HAT) activator that can be used in the preparation of hair growth promoters and/or hair loss treatments.</p>Formula:C31H43ClF3NO2Purity:99.77%Color and Shape:SolidMolecular weight:554.13SirReal-1
CAS:<p>SirReal-1 is an effective and selective inhibitor of Sirt2.</p>Formula:C18H18N4OS2Purity:98%Color and Shape:SolidMolecular weight:370.49Prospasmine
CAS:<p>Prospasmine is an anticholinergic.</p>Formula:C17H28ClNO2Purity:98%Color and Shape:SolidMolecular weight:313.87JAK3-IN-12
CAS:<p>JAK3-IN-12 (compound 15k) is a potent inhibitor of JAK3 (IC50: 9.5 nM) and can be used in the study of rheumatoid arthritis.</p>Formula:C19H19N5O4SColor and Shape:SolidMolecular weight:413.45Hns 32
CAS:<p>Hns 32 possesses antiarrhythmic properties in dog and guinea pig hearts. It also has vasodilator action.</p>Formula:C24H29N3Purity:98%Color and Shape:SolidMolecular weight:359.51p32 Inhibitor M36
CAS:<p>p32 inhibitor M36 is an inhibitor of p32 mitochondrial protein. It binds directly to p32 and inhibits the p32 association with LyP-1.</p>Formula:C23H28N8O2Purity:98%Color and Shape:SolidMolecular weight:448.52AMPK activator 1
CAS:<p>AMPK activator 1 is an AMPK activator(compound No.1-75, EC50: <0.1μM).</p>Formula:C32H33F3N4O3Purity:98%Color and Shape:SolidMolecular weight:578.62ST7710AA1
CAS:<p>ST7710AA1 inhibits PARP-1, effectively targets in vitro, and overcomes Pgp-associated multidrug resistance.</p>Formula:C20H22N4OColor and Shape:SolidMolecular weight:334.41NCGC00247743
CAS:<p>NCGC00247743 is an inhibitor of histone lysine demethylase KDM4.</p>Formula:C24H29N3O2Purity:98%Color and Shape:SolidMolecular weight:391.51MI-3
CAS:<p>MI-3 (Menin-MLL Inhibitor) (Menin-MLL Inhibitor) is an effective inhibitor of Menin-MLL interaction (IC50: 648 nM).</p>Formula:C18H25N5S2Purity:98.66% - 99.61%Color and Shape:SolidMolecular weight:375.55GPI-15427
CAS:<p>GPI-15427: a potent PARP-1 inhibitor, crosses the blood-brain barrier, boosts TMZ's effects on CNS tumors, and sensitizes cancer to radiotherapy.</p>Formula:C20H20N4O2Color and Shape:SolidMolecular weight:348.4Binucleine 2
CAS:<p>Binucleine 2: Drosophila Aurora B kinase inhibitor (Ki=0.36μM), dose-dependent, minimal effect on human/X. laevis kinases, disrupts mitosis in fly cells.</p>Formula:C13H11ClFN5Color and Shape:SolidMolecular weight:291.71GSK926
CAS:<p>GSK926 is a selective, SAM-competitive, and cell-active EZH2 inhibitor.</p>Formula:C29H35N7O2Color and Shape:SolidMolecular weight:513.63CREBBP-IN-9
CAS:<p>CREBBP-IN-9, a CREBBP inhibitor, acts on the bromodomain of the protein.</p>Formula:C16H15N5O2SPurity:98%Color and Shape:SolidMolecular weight:341.39CPI-1612
CAS:<p>CPI-1612: Oral EP300/CBP HAT inhibitor, IC50 8.1 nM, has anticancer properties.</p>Formula:C27H26N6OColor and Shape:SolidMolecular weight:450.53HDAC-IN-28
CAS:<p>HDAC-IN-28 is a novel inhibitor of HDAC that significantly inhibits tumour growth and metastasis.</p>Formula:C23H26N4O4SColor and Shape:SolidMolecular weight:454.54SDR-04
CAS:<p>SDR-04 inhibits BRD4-BD1 with high affinity, suppressing MV4;11 cancer cell growth as a BET inhibitor.</p>Formula:C19H16N4O2Color and Shape:SolidMolecular weight:332.36H8-A5
CAS:<p>H8-A5, a HDAC8 inhibitor, shows antiproliferation activity in MDA-MB-231 cancer cells.</p>Formula:C14H9F3N2O2SPurity:98%Color and Shape:SolidMolecular weight:326.29ZLD2218
CAS:<p>ZLD2218, a potent inhibitor of BRD4 with an IC50 value of 107 nM, has been demonstrated to mitigate kidney injury and fibrosis through extensive studies.</p>Formula:C22H18N4OColor and Shape:SolidMolecular weight:354.4TK4g
CAS:<p>TK4g, a potent JAK inhibitor, has IC50s of 12.61 nM (JAK2) & 15.80 nM (JAK3); promising for lymphoid diseases & leukemia research.</p>Formula:C19H19N3O4SColor and Shape:SolidMolecular weight:385.44BRD4 Inhibitor-19
CAS:<p>BRD4 inhibitors -19 are BET inhibitors that act on BRD4-BD1 (IC50: 55 nM) and can be used to study multiple myeloma.</p>Formula:C29H25N5O3Color and Shape:SolidMolecular weight:491.54Arazine
CAS:<p>Arazine, a cell-permeable G protein modulator, is an isoprenylcysteine methyltransferase substrate.</p>Formula:C20H33NO3SPurity:90%Color and Shape:SolidMolecular weight:367.55PARP1-IN-11
CAS:<p>PARP1-IN-11 is a potent PARP1 inhibitor (IC50=0.082 μM), also reducing PARP3, TNKS1, and TNKS2 activity.</p>Formula:C16H12N2O4Color and Shape:SolidMolecular weight:296.28WD2000-012547
CAS:<p>WD2000-012547 is a selective inhibitor of poly(ADP-ribose)-polymerase (PARP-1) (pKi: 8.221).</p>Formula:C17H14N2OPurity:98%Color and Shape:SolidMolecular weight:262.31NV03
CAS:<p>NV03 is a selective antagonist of the UHRF1-H3K9me3 interaction (Kd=2.4 μM) for cancer research. a ligand for E3 ligases in PROTAC synthesis.</p>Formula:C19H27N5O2SPurity:99.88%Color and Shape:SolidMolecular weight:389.52MS453
CAS:<p>MS453 is a potent and selective SETD8 inhibitor with an IC50 value of 804 nM.</p>Formula:C20H27N5O3Color and Shape:SolidMolecular weight:385.46NR-160
CAS:<p>NR-160 is a selective HDAC6 inhibitor (IC50=0.03μM), weaker on HDAC1-4,8, toxic to 7 cancer lines, boosts bortezomib and anthracycline effects.</p>Formula:C25H21F3N6O3Color and Shape:SolidMolecular weight:510.47M122
CAS:<p>M122 is a selective histone deacetylase HDAC1 and HDAC2 inhibitor and potent antitumor agent.</p>Formula:C24H25N5OS2Color and Shape:SolidMolecular weight:463.62UMB-32
CAS:<p>UMB-32: Potent, selective BRD4 inhibitor, Kd 550 nM, IC50 637 nM, also targets TAF1.</p>Formula:C21H23N5OColor and Shape:SolidMolecular weight:361.44CTK7A
CAS:<p>CTK7A is a water-soluble inhibitor of p300. CTK7A inhibits tumor growth in xenografted mice.</p>Formula:C28H24N2NaO6Purity:98%Color and Shape:SolidMolecular weight:507.498Bromodomain inhibitor-10
CAS:<p>Bromodomain inhibitor-10 (compound 128) suppresses BRD4-1/2 with Kd 15 nM/2.5 μM and curbs IL12p40 production.</p>Formula:C20H20N4O3Color and Shape:SolidMolecular weight:364.4MAT2A inhibitor 1
CAS:<p>MAT2A inhibitor 1 is an inhibitor of methionine adenosyltransferase 2A (MATA2) (IC50 < l00 nM).</p>Formula:C31H22N6OSColor and Shape:SolidMolecular weight:526.61FNDR-20123 free base
CAS:<p>FNDR-20123 is a safe, oral first-in-class anti-malarial HDAC inhibitor with low IC50s against Plasmodium and human HDACs.</p>Formula:C21H23N5O2Color and Shape:SolidMolecular weight:377.44TAK-418
CAS:<p>TAK-418 is an orally active LSD1/KDM1A inhibitor with a 2.9 nM IC50, potential for autism therapy.</p>Formula:C17H25ClN2O2SPurity:99.69%Color and Shape:SolidMolecular weight:356.91SB-429201
CAS:<p>SB-429201 is an effective, selective inhibitor of HDAC1.</p>Formula:C28H24N2O3Purity:98%Color and Shape:SolidMolecular weight:436.5CAY10669
CAS:<p>CAY10669 inhibits PCAF (IC50 = 662 μM), is twice as potent as anacardic acid, and reduces H4 acetylation in HepG2 cells at 30-60 μM.</p>Formula:C20H22O4Color and Shape:SolidMolecular weight:326.39JNJ-7925476 free base
CAS:<p>JNJ-7925476 is an TRI antidepressant agent.</p>Formula:C20H19NPurity:98%Color and Shape:SolidMolecular weight:273.37PF-00956980
CAS:<p>PF-00956980: reversible JAK inhibitor, IC50: JAK1 (2.2μM), JAK2 (23.1μM), JAK3 (59.9μM), for lung/skin inflammation research.</p>Formula:C18H26N6OColor and Shape:SolidMolecular weight:342.44UNC6212 (Kme2)
<p>UNC6212 (Kme2), a dimethyllysine (Kme2)-containing ligand, has a K D for CBX5 of 5.7 μM .</p>Formula:C39H53N7O11Color and Shape:SolidMolecular weight:795.88BAY-598 R-isomer
CAS:<p>BAY-598 R-isomer, a SMYD2-selective inhibitor, is the R-enantiomer of BAY589, not targeting PAR1.</p>Formula:C22H20Cl2F2N6O3Color and Shape:SolidMolecular weight:525.34J1075
CAS:<p>J1075 is an histone deacetylase 8 (HDAC8) inhibitor.</p>Formula:C9H6ClNO2SPurity:98%Color and Shape:SolidMolecular weight:227.67S-Aristeromycinylhomocysteine
CAS:<p>S-Aristeromycinylhomocysteine is an inhibitor of adenosylmethionine decarboxylase.</p>Formula:C15H22N6O4SColor and Shape:SolidMolecular weight:382.44(R)-OR-S1
CAS:<p>(R)-OR-S1 is a SAM-competitive, highly selective, orally bioavailable dual inhibitor of EZH1/2.</p>Formula:C26H34BrN3O4Purity:98%Color and Shape:SolidMolecular weight:532.47
