Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2597 products of "Chromatin/Epigenetics"
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Piribedil dihydrochloride
CAS:dopamine agonistFormula:C16H20Cl2N4O2Purity:98%Color and Shape:SolidMolecular weight:371.26Dot1L-IN-7
CAS:Dot1L-IN-7 (compound 25), a potent DOT1L inhibitor with an IC50 of 1.0 μM, selectively kills MLL-AF9, sparing E2A-HLF cells.Formula:C23H27N9O2Color and Shape:SolidMolecular weight:461.526-Methyl-5-azacytidine
CAS:6-Methyl-5-azacytidine is a potent DNMT inhibitor.Formula:C9H14N4O5Purity:98%Color and Shape:SolidMolecular weight:258.23LT052
CAS:LT052 is a BET BD1 inhibitor with anti-inflammatory activity. It mediates the BRD4/NF-κB/NLRP3 signaling inflammatory pathway.Formula:C22H19N5O4SPurity:98.82%Color and Shape:SolidMolecular weight:449.48AMPK activator 4
CAS:Potent, selective AMPK activator 4 enhances glucose tolerance and insulin sensitivity without affecting mitochondrial complex I.Formula:C24H21ClN2O3Purity:99.97% - 99.99%Color and Shape:SolidMolecular weight:420.89Ref: TM-T62238
1mg86.00€5mg173.00€10mg334.00€25mg563.00€50mg802.00€100mg1,099.00€500mg2,187.00€1mL*10mM (DMSO)203.00€PI3K/HDAC-IN-1
CAS:PI3K/HDAC-IN-1 is a potent PI3K and HDAC dual inhibitor(IC50s of 8.1 nM and 1.4 nM, respectively).
Formula:C22H25FN4O4Purity:98%Color and Shape:SolidMolecular weight:428.46BRD4 Inhibitor-19
CAS:BRD4 inhibitors -19 are BET inhibitors that act on BRD4-BD1 (IC50: 55 nM) and can be used to study multiple myeloma.Formula:C29H25N5O3Color and Shape:SolidMolecular weight:491.54TK4g
CAS:TK4g, a potent JAK inhibitor, has IC50s of 12.61 nM (JAK2) & 15.80 nM (JAK3); promising for lymphoid diseases & leukemia research.Formula:C19H19N3O4SColor and Shape:SolidMolecular weight:385.44Lorpucitinib
CAS:Lorpucitinib (JNJ-64251330) is a JAK kinase inhibitor used in the study of inflammatory and gastrointestinal diseases.Formula:C22H28N6O2Purity:99.72%Color and Shape:SolidMolecular weight:408.5TyK2-IN-2
CAS:TyK2-IN-2 is a selective inhibitor of TYK2 (IC50s: 7 nM, 0.1 μM, and 0.05 μM for TYK2 JH2, IL-23, and IFNα).Formula:C16H18N6OPurity:98%Color and Shape:SolidMolecular weight:310.35Tripartin
CAS:Tripartin specifically inhibits the histone H3 lysine 9 demethylase KDM4 in HeLa cells.Formula:C10H8Cl2O4Color and Shape:SolidMolecular weight:263.07BRD4884
CAS:BRD4884 is a highly selective and efficient HDAC1 and HDAC2 inhibitor that also inhibits HDAC3, used in research on neurological disorders.Formula:C18H19FN2O2Purity:99.19% - 99.21%Color and Shape:SolidMolecular weight:314.35CPI703
CAS:CPI703 is a novel potent and specific CBP/EP300 bromodomain inhibitor.Formula:C17H22N4OPurity:98%Color and Shape:SolidMolecular weight:298.38CCT077791
CAS:CCT077791 is a potent inhibitor of p300 and PCAF histone acetyltransferase activity for cancer research.Formula:C9H5ClN2O3SPurity:98.60%Color and Shape:SolidMolecular weight:256.67UNC2327
CAS:UNC2327 is a potent and selective inhibitor of protein arginine methyltransferase 3 (PRMT3) (IC50:230 nM).Formula:C14H17N5O2SPurity:98%Color and Shape:SolidMolecular weight:319.38BAY1238097
CAS:BAY1238097 is a BET inhibitor with anticancer activity and antiproliferative activity for the study of advanced refractory malignancies.Formula:C25H33N5O3Purity:98.1% - 98.79%Color and Shape:SolidMolecular weight:451.56Ref: TM-T12660L
1mg49.00€5mg101.00€10mg172.00€25mg355.00€50mg620.00€100mg1,044.00€200mg1,404.00€1mL*10mM (DMSO)113.00€CMP-5 hydrochloride
CAS:CMP-5 hydrochloride: potent, selective PRMT5 inhibitor; inactive against PRMT1/4/7; blocks S2Me-H4R3 on histones.Formula:C21H22ClN3Purity:98%Color and Shape:SolidMolecular weight:351.87Dimethyl-bisphenol A
CAS:DMBPA inhibits HIF-1α, promotes its degradation by detaching Hsp90, and reduces Vegfa mRNA expression.Formula:C17H20O2Color and Shape:SolidMolecular weight:256.34p32 Inhibitor M36
CAS:p32 inhibitor M36 is an inhibitor of p32 mitochondrial protein. It binds directly to p32 and inhibits the p32 association with LyP-1.Formula:C23H28N8O2Purity:98%Color and Shape:SolidMolecular weight:448.52aPKC-I
CAS:aPKC-I specifically inhibits PKCζ/i, blocks VEGF effects, and prevents IR-induced permeability in cells and live models.Formula:C15H17NO4SColor and Shape:SolidMolecular weight:307.36NAT2-IN-1
CAS:NAT2-IN-1 (APA) is a selective inhibitor of the drug metabolism enzyme N-acetyltransferase 2 (NAT2), capable of targeting and eliminating cells with slow NAT2Formula:C19H20N4O3Color and Shape:SolidMolecular weight:352.39SC-10
CAS:SC-10 is a direct activator of PKC with potential antiproliferative activity, useful in leukemia research.Formula:C17H22ClNO2SPurity:99.24% - 99.58%Color and Shape:SolidMolecular weight:339.88Tinostamustine HCl
CAS:Tinostamustine (EDO-S101) is an alkylating HDACi fusion molecule, enhancing potency and overcoming drug resistance.Formula:C19H29Cl3N4O2Color and Shape:SolidMolecular weight:451.82JNJ-9350
CAS:JNJ-9350: SMOX inhibitor (IC50 0.01 μM), PAO inhibitor (IC50 0.79 μM), for cancer research.Formula:C25H22N6OColor and Shape:SolidMolecular weight:422.48CAY10721
CAS:CAY10721 inhibits SIRT3 (39% at 200 μM), linked to OSCC and breast cancer; lowers OSCC growth, enhances radio/chemo sensitivity.Formula:C18H13N3O3SColor and Shape:SolidMolecular weight:351.38CSV0C018875 Hydrochloride
CAS:CSV0C018875 Hydrochloride: Novel G9a inhibitor with low toxicity, effective in enzyme/cell assays, outperforms BIX-0129.Formula:C18H18Cl2N2OColor and Shape:SolidMolecular weight:349.255MC4343
MC4343, a potent dual inhibitor targeting both EZH2 and histone deacetylase, presents promising potential for cancer research applications.Formula:C36H41N5O4Color and Shape:SolidMolecular weight:607.74TK4b
CAS:TK4b, a JAK inhibitor, targets leukemia/lymphoid diseases, with IC50s: 18.42 nM (JAK3) & 19.40 nM (JAK2).Formula:C21H22N2O2Color and Shape:SolidMolecular weight:334.41HMS607P03
CAS:HMS607P03 is an activator of SIRT1 which induces autophagic cell death via the AMPK-mTOR-ULK complex and induces mitophagy by the SIRT1-PINK1-Parkin pathway.Formula:C26H19ClN4O3S2Color and Shape:SolidMolecular weight:535.04MicroRNA-21-IN-2
CAS:MicroRNA-21-IN-2 is a potential miR-21 inhibitor with an AC50 value of 3.29 μM. MicroRNA-21-IN-2 can be used to study cancer.Formula:C17H15N3O3SPurity:99.45%Color and Shape:SolidMolecular weight:341.38Cercosporamide
CAS:Cercosporamide is a ATP-competitive Pkc1 kinase inhibitor (IC50 <50 nM; Ki <7 nM). It also is a unique Mnk inhibitor.Formula:C16H13NO7Purity:98%Color and Shape:SolidMolecular weight:331.285-Octyl-α-ketoglutarate
CAS:In addition to its role in the Krebs cycle, α-ketoglutarate (2-oxoglutarate) has roles as a substrate or modulator of enzymes.Formula:C13H22O5Color and Shape:SolidMolecular weight:258.31AMPK activator 6
CAS:AMPK activator 6 stimulates AMPK, lowers lipids in cells, and reduces serum TC, LDL-C, and TG. Useful for NAFLD and metabolic research.Formula:C25H28O5Color and Shape:SolidMolecular weight:408.49HAT-IN-1
CAS:HAT-IN-1 is an inhibitor of HAT used in the research of cancer.Formula:C23H18BrF4N3O4Purity:98%Color and Shape:SolidMolecular weight:556.3Bizine dihydrochloride
CAS:Bizine dihydrochloride is a potent LSD1 inhibitor in vitro, being selective versus monoamine oxidases A/B and the LSD1 homologue, LSD2.Formula:C18H25Cl2N3OColor and Shape:SolidMolecular weight:370.32Furamidine
CAS:Furamidine is a PRMT1-selective, cell-permeable inhibitor (IC50: 9.4μM), also targeting TDP-1, and is an antiparasitic bisbenzamidine derivative.Formula:C18H16N4OPurity:98%Color and Shape:SolidMolecular weight:304.35HDAC ligand-1
CAS:HDAC ligand-1 is a synthetic precursor utilized in the production of PROTAC-based HDAC degraders [1].Formula:C7H8N2OPurity:98%Color and Shape:SolidMolecular weight:136.15PRMT5:MEP50 PPI
PRMT5:MEP50 PPI inhibitor with anti-tumor and anti-proliferative effects on lung and prostate cancers.Formula:C24H22N4O4Color and Shape:SolidMolecular weight:430.46JFD00244
CAS:JFD00244 is an inhibitor of sirtuin 2 (SIRT2). It has an anti-tumor effect.Formula:C30H26N2O4Purity:98%Color and Shape:SolidMolecular weight:478.54JAK-2/3-IN-2
CAS:JAK-2/3-IN-2 (Compound 3h) is a potent JAK2 & JAK3 inhibitor with IC50s of 23.85 nM (JAK2) & 18.9 nM (JAK3).Formula:C19H19ClN2OSColor and Shape:SolidMolecular weight:358.89CAY10727
CAS:CAY10727 selectively inhibits PAD3 (15,600 M^-1min^-1) over PAD1, PAD2, and PAD4.Formula:C21H22Cl2N4O2Color and Shape:SolidMolecular weight:433.33NL-103
CAS:NL-103, a dual-targeting compound, inhibits HDACs & Hh pathway, countering vismodegib-resistant Smo mutations.Formula:C26H27Cl2N5O4Color and Shape:SolidMolecular weight:544.43EPZ033294
CAS:EPZ033294 has potential anticancer and antiproliferative activity.Formula:C20H22ClN7OPurity:99.95%Color and Shape:SolidMolecular weight:411.89A2B57
CAS:A2B57 is a selective SIRT2 inhibitor.Formula:C22H19N5OPurity:98%Color and Shape:SolidMolecular weight:369.42JJO-1
CAS:JJO-1 is a bi-quinoline activating all AMPK αβγ isoforms except γ3; it requires low ATP and is unaffected by γ mutations or β deletions.Formula:C19H13N3Color and Shape:SolidMolecular weight:283.33A2AAR/HDAC-IN-1
CAS:A2AAR/HDAC-IN-1 (compound 14c) is an orally active, balanced A2AAR/HDAC dual inhibitor of A2AAR (Ki: 163.5 nM), HDAC1 (IC50: 145.3 nM). effect.Formula:C24H21N7O2Color and Shape:SolidMolecular weight:439.47MARK-IN-4
CAS:MARK-IN-4 inhibits microtubule kinase (MARK) effectively (IC50: 1 nM), a target for Alzheimer's therapy.Formula:C21H23N7OSColor and Shape:SolidMolecular weight:421.52PARP1-IN-9
CAS:PARP1-IN-9, potent PARP1 inhibitor with 30.51 nM IC50, outperforms Olaparib in anticancer efficacy.Formula:C18H21N3O5Color and Shape:SolidMolecular weight:359.38NCDM-32B
CAS:NCDM-32B, a novel potent and selective KDM4 inhibitor, impairs viability and transforms phenotypes of basal breast cancer.Formula:C15H30N2O4Purity:98%Color and Shape:SolidMolecular weight:302.41DM-NOFD
CAS:DM-NOFD is a cell penetrant prodrug of NOFD, which is a potent and selective inhibitor of an asparaginyl hydroxylase FIH (factor-inhibiting HIF).Formula:C13H15NO5Color and Shape:SolidMolecular weight:265.26
