Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2235 products of "Chromatin/Epigenetics"
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PKN1/2-IN-1
CAS:<p>PKN1/2-IN-1 is a potent and selective PKN2 inhibitor, membrane permeability and anticancer.Protein kinase N proteins (PKN) are effectors of Rho GTPases.</p>Formula:C14H15N3OPurity:99.72%Color and Shape:SolidMolecular weight:241.29BiBET
CAS:<p>BiBET is a potent, selective, bivalent inhibitor of BET bromodomains.</p>Formula:C26H30N10O3Color and Shape:SolidMolecular weight:530.58KDM2B-IN-3
CAS:<p>KDM2B-IN-3, from patent WO2016112284A1 as compound 183c, potently inhibits histone demethylase KDM2B, with cancer research potential.</p>Formula:C25H30N2O2Color and Shape:SolidMolecular weight:390.52GS-626510
CAS:<p>GS-626510 is an orally bioavailable inhibitor of BET family bromodomains (Kd: 0.59-3.2 nM for BRD2/3/4; IC50: 83 nM and 78 nM for BD1 and BD2).</p>Formula:C25H22N4OColor and Shape:SolidMolecular weight:394.47AMPK activator
CAS:<p>AMPK activator</p>Formula:C22H21FO4Purity:98%Color and Shape:SolidMolecular weight:368.41,2-Didecanoylglycerol
CAS:<p>1,2-Didecanoylglycerol has functions as bioregulator of protein kinase C in human platelets.</p>Formula:C23H44O5Color and Shape:SolidMolecular weight:400.59LW479
CAS:<p>LW479 is a novel inhibitor of HDAC and is a promising candidate for the prevention of breast cancer.</p>Formula:C21H23BrN2O4SColor and Shape:SolidMolecular weight:479.39NSD3-IN-1
CAS:<p>NSD3-IN-1, a histone methyltransferase NSD3 inhibitor, demonstrates an IC50 of 28.58 μM.</p>Formula:C13H13N5OSColor and Shape:SolidMolecular weight:287.34HPB
CAS:<p>HPB is a selective HDAC6 deacetylase inhibitor</p>Formula:C18H20N2O4Color and Shape:SolidMolecular weight:328.36KDM5A-IN-1
CAS:<p>KDM5A-IN-1 is a pan-histidine lysine demethylase 5 KDM5 inhibitor that inhibits KDM5A, KDM5B, and KDM5C.Can be used in the study of cancer.</p>Formula:C15H22N4O2Purity:>99.99%Color and Shape:SolidMolecular weight:290.36Galegine hydrochloride
CAS:<p>Galegine hydrochloride, from G. officinalis, leads to weight loss, activates AMPK in various cells, and has antibacterial properties.</p>Formula:C6H14ClN3Color and Shape:SolidMolecular weight:163.65DC_517
CAS:<p>DC_517 is an inhibitor of DNA methyltransferase 1 (DNMT1) ( IC50: 1.7 μM; Kd: 0.91 μM).</p>Formula:C33H35N3O2Color and Shape:SolidMolecular weight:505.65HDAC-IN-43
CAS:<p>HDAC-IN-43: potent HDAC 1/3/6 inhibitor (IC50: 82 nM HDAC1, 45 nM HDAC3, 24 nM HDAC6); weak PI3K/mTOR (IC50: 3.6μM, 3.7μM); anti-proliferative.</p>Formula:C22H28N6O4Color and Shape:SolidMolecular weight:440.5L 888607 Racemate
CAS:<p>L 888607 Racemate blocks DP1 and TP receptors with 132 nM and 17 nM affinity.</p>Formula:C19H15ClFNO2SColor and Shape:SolidMolecular weight:375.84Tyk2-IN-7
CAS:<p>Tyk2-IN-7 is an inhibitor of TYK2 JH2, binds to the TYK2 JH2 domain (IC50: 0.00053 μM; Ki.app: 0.00007 μM).</p>Formula:C18H15D3N6O3SPurity:98%Color and Shape:SolidMolecular weight:401.46TK4b
CAS:<p>TK4b, a JAK inhibitor, targets leukemia/lymphoid diseases, with IC50s: 18.42 nM (JAK3) & 19.40 nM (JAK2).</p>Formula:C21H22N2O2Color and Shape:SolidMolecular weight:334.41Pulrodemstat Methylbenzenesulfonate
CAS:<p>LSD1-IN-7 Methylbenzenesulfonate is a potent and orally active inhibitor of lysine specific demethylase-1 (LSD1) with anticancer activity.</p>Formula:C31H31F2N5O5SPurity:98%Color and Shape:SolidMolecular weight:623.67ZIKV-IN-3
CAS:<p>ZIKV-IN-3, an andrographolide derivative, inhibits ZIKV NS5 MTase (IC50: 18.34 μM) and replication. Used for Zika virus research.</p>Formula:C39H41NO4Color and Shape:SolidMolecular weight:587.75YM-53601 free base
CAS:<p>YM-53601 free base is an inhibitor of squalene synthetase which suppresses lipogenic biosynthesis and lipid secretion in rodents.</p>Formula:C21H21FN2OPurity:98%Color and Shape:SolidMolecular weight:336.4EP009
CAS:<p>EP009, a novel, selective, and orally active inhibitor of JAK3, induces therapeutic response in T-cell malignancies.</p>Formula:C14H24O2Color and Shape:SolidMolecular weight:224.34MDK8228
CAS:<p>MDK8228 is an inhibitor of CBP/p300 and BRD4 bromodomain. MDK8228 downregulates IL-6, IL-ß and IFN-ß in macrophages.</p>Formula:C31H41N5O3Color and Shape:SolidMolecular weight:531.69NVS-BET-1
CAS:<p>NVS-BET-1 is a BET bromodomain inhibitor. NVS-BET-1 can regulate keratinocyte plasticity.</p>Formula:C22H21ClN4O2Color and Shape:SolidMolecular weight:408.88SIRT2-IN-11
CAS:<p>SIRT2-IN-11 (AEM1), a SIRT2 inhibitor (IC50 18.5μM), induces apoptosis and affects p53, used in cancer research.</p>Formula:C21H22N2OColor and Shape:SolidMolecular weight:318.41RM65
CAS:<p>RM65 is an arginine methyltransferase inhibitor.</p>Formula:C34H32N2O4S2Purity:98%Color and Shape:SolidMolecular weight:596.76HIF-1α-IN-3
CAS:<p>HIF-1α-IN-3, also known as Compound (S)-3f, is a hypoxia-selective inhibitor of HIF-1α. It exhibits potent antiestrogenic activity [1].</p>Formula:C19H17N5O2Color and Shape:SolidMolecular weight:347.37CBB1003
CAS:<p>CBB1003 is a new inhibitor of histone demethylase LSD1 (IC50: 10.54 μM).</p>Formula:C25H31N9O4Purity:98%Color and Shape:SolidMolecular weight:521.57PF-739
CAS:<p>PF-739 is an AMPK agonist that has been shown to activate AMPK in hepatocytes and skeletal muscle.</p>Formula:C23H23ClN2O5Purity:98%Color and Shape:SolidMolecular weight:442.89HDAC-IN-29
CAS:<p>HDAC-IN-29 (compound 13b) is a potent pan- HDAC inhibitor with antitumor activity.</p>Formula:C20H23N3O4SColor and Shape:SolidMolecular weight:401.48DC-BPi-03
CAS:<p>DC-BPi-03 is a potent BPTF-BRD inhibitor with an IC 50 of 698.3 nM and a K d of 2.81 μM .</p>Formula:C14H14N4O2SPurity:98.96%Color and Shape:SolidMolecular weight:302.35Butyrolactone 3
CAS:<p>Butyrolactone 3 (MB-3) is a Gcn5 inhibitor with weak affinity for CBP.Butyrolactone 3 has antimicrobial activity and can be used in cancer.</p>Formula:C9H12O4Purity:98.99% - 99.5%Color and Shape:SolidMolecular weight:184.19EZH2-IN-13
CAS:<p>EZH2-IN-13 is a potent EZH2 inhibitor with potential anticancer activity.EZH2-IN-13 may be used to study diseases associated with EZH2 activity.</p>Formula:C34H45N5O3Purity:98.3%Color and Shape:SolidMolecular weight:571.75Butyzamide
CAS:<p>Butyzamide: oral Mpl activator, non-peptide, antagonizes TPO receptors, boosts hMpl, Ba/F3 cells, and enhances platelets in mice.</p>Formula:C29H32Cl2N2O5SPurity:99.51% - 99.83%Color and Shape:SoildMolecular weight:591.55TNG908
CAS:<p>TNG908, a brain-penetrant PRMT5 inhibitor, is 15x more selective for MTAP mutant vs WT lines, useful in cancer studies.</p>Formula:C21H23N5O2SPurity:98.08% - 98.24%Color and Shape:SolidMolecular weight:409.51PU139
CAS:<p>PU139 is a novel inhibitor of histone acetyltransferase (HAT).</p>Formula:C12H7FN2OSPurity:99.96%Color and Shape:SolidMolecular weight:246.26Crebinostat
CAS:<p>Crebinostat: potent HDAC inhibitor, boosts synapsin-1 in neurons, enhances memory and gene Egr1 expression in mice.</p>Formula:C20H23N3O3Purity:94.96%Color and Shape:SolidMolecular weight:353.41DCPLA-ME
CAS:<p>DCPLA-ME (2-[(2-Pentylcyclopropyl)methyl]cyclopropaneoctanoic acid methyl ester) is the methyl ester form of DCPLA and can be used to treat neurodegenerative</p>Formula:C21H38O2Purity:99.80%Color and Shape:SolidMolecular weight:322.53STS-E412
CAS:<p>STS-E412 is a tissue-protective and selective EPOR/CD131 receptor activator for the study of neurological disorders.</p>Formula:C15H15ClN4O2Purity:99.01%Color and Shape:SolidMolecular weight:318.76Raxofelast
CAS:<p>Raxofelast (IRFI-016), a vitamin-like, hydrophilic antioxidant, mitigates ischemia-reperfusion in testis and may treat diabetic issues and atherosclerosis.</p>Formula:C15H18O5Purity:99.74% - 99.97%Color and Shape:SolidMolecular weight:278.3BAY-299
CAS:<p>BAY-299 inhibits BRPF2, TAF1, and TAF1L with IC50s of 67, 8, and 106 nM.</p>Formula:C25H23N3O4Purity:99.53%Color and Shape:SolidMolecular weight:429.47LEM-14
CAS:<p>LEM-14 is a potent NSD2-specific inhibitor (IC50:132 μM).LEM-14 may be used in the study of multiple myeloma.</p>Formula:C25H26N4O4SPurity:98.3%Color and Shape:SolidMolecular weight:478.56CMP-5
CAS:<p>CMP-5 is a PRMT5 inhibitor with antiviral activity, inhibits PRMT5 methyltransferase activity, and can be used in the study of SARS virus infection.</p>Formula:C21H21N3Purity:98.68%Color and Shape:SolidMolecular weight:315.41TM2-115
CAS:<p>TM2-115 is a inhibitor of malaria parasite histone methyltransferases that results in rapid and irreversible parasite death [1].</p>Formula:C28H38N6O2Purity:97.67%Color and Shape:SolidMolecular weight:490.64ZEN-3219
CAS:<p>ZEN-3219 is a BET inhibitor, which has inhibitory effect on BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2).</p>Formula:C19H18N2O3Purity:99.06%Color and Shape:SolidMolecular weight:322.36TGP-377/421
CAS:<p>TGP-377/421 (Targapre-miR-377/421) is a potent miR-377 and miR-421 dual inhibitor that inhibits miR-377 and miR-421 by binding to their functional sites.</p>Formula:C20H16N6Purity:98.48%Color and Shape:SolidMolecular weight:340.38DW14800
CAS:<p>DW14800 is an inhibitor of PRMT5 (IC50 = 17 nM), enhances the transcription of HNF4α, and reduces the level of H4R3me2s.</p>Formula:C31H36N4O3Purity:99.55% - 99.68%Color and Shape:SolidMolecular weight:512.64Cedazuridine
CAS:<p>Cedazuridine ((4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine) is an oral inhibitor of cytidine deaminase with antineoplastic properties.</p>Formula:C9H14F2N2O5Purity:99.66%Color and Shape:SolidMolecular weight:268.21CEP-9722
CAS:<p>CEP-9722 is a PARP-1 and PARP-2 inhibitor with anticancer activity and is used in the study of ovarian cancer.</p>Formula:C24H26N4O3Purity:98.38% - 98.56%Color and Shape:SolidMolecular weight:418.49GRK6-IN-1
CAS:<p>GRK6-IN-1 (compound 18) is a potent GRK6 blocker, with an IC50 of 120 nM, showing promise for multiple myeloma research.</p>Formula:C22H23ClN6O2Purity:99.37%Color and Shape:SolidMolecular weight:438.91Procainamide
CAS:<p>Procainamide: DNMT1 inhibitor, Class 1A antiarrhythmic, promising for cancer and arrhythmia research.</p>Formula:C13H21N3OPurity:99.92% - 99.92%Color and Shape:SolidMolecular weight:235.33CPUY074020
CAS:<p>CPUY074020 is a potent and orally bioavailable inhibitor of histone methyltransferase G9a (IC50: 2.18 μM) with anti-proliferative activity.</p>Formula:C25H28N4O2Purity:98.64%Color and Shape:SolidMolecular weight:416.52
