Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2486 products of "Chromatin/Epigenetics"
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JAK-IN-4
CAS:JAK-IN-4 is a prodrug of a JAK inhibitor, effective in murine collagen induced arthritis model.Formula:C18H21N4Na2O6PPurity:98%Color and Shape:SolidMolecular weight:466.341Sirt2-IN-5
CAS:Sirt2-IN-5 is a potent inhibitor of SIRT2.Formula:C26H27Cl2N5O3Color and Shape:SolidMolecular weight:528.43CLB-016
CAS:CLB-016 is an inhibitor of hypoxia-inducible factor (HIF)-1.Formula:C17H20N6O3Purity:98%Color and Shape:SolidMolecular weight:356.38KAT modulator-1
CAS:KAT modulator-1 (Compound 3), an epigenetics research tool, selectively interacts with the full-length p300 protein but not its catalytic domain [1].Formula:C20H36O2Purity:98%Color and Shape:SolidMolecular weight:308.5Antitumor agent-101
CAS:Antitumor agent-101 is a selective, covalent inhibitor targeting lysine methyltransferases G9a/GLP, demonstrating IC50 values of 8.5 nM for G9a and 5.5 nM forFormula:C26H38N6O3Purity:98%Color and Shape:SolidMolecular weight:482.62CBP/p300-IN-19 hydrochloride
CAS:CBP/p300-IN-19 HCl is a p300/CBP HAT inhibitor (IC50: p300 1.4 μM, CBP 2.2 μM) with antitumor properties.Formula:C30H28ClN3O3Color and Shape:SolidMolecular weight:514.02SJ1461
CAS:SJ1461 is a potent, orally active inhibitor of the BET family, selectively targeting and inhibiting BRD2 (BD1), BRD2 (BD2), BRD4 (BD1), and BRD4 (BD2) withFormula:C21H18ClN7OS2Purity:98%Color and Shape:SolidMolecular weight:484HSP70/SIRT2-IN-2
CAS:<p>HSP70/SIRT2-IN-2 (Compounds 1a), a dual inhibitor of SIRT2 and HSP70, exhibits an IC50 of 45.1±5.0 μM against SIRT2 and demonstrates antitumor activity [1].</p>Formula:C17H13N3S3Purity:98%Color and Shape:SolidMolecular weight:355.5A1B11
CAS:A1B11 is a selective SIRT2 inhibitor.Formula:C22H25N5OColor and Shape:SolidMolecular weight:375.47AMPK activator 7
CAS:<p>AMPK activator 7 (I-3-24, EC50: 8.8 nM) targets AMPK-related disorders like type 2 diabetes and obesity.</p>Formula:C23H22F3N3O5Color and Shape:SolidMolecular weight:477.43PF-06679142
CAS:PF-06679142 is an effective AMPK activator. PF-06679142 exhibited robust activation of AMPK in rat kidneys as well as desirable oral absorption.Formula:C20H17F2NO3Purity:98%Color and Shape:SolidMolecular weight:357.35TC-AC28
CAS:TC-AC28 is a novel potent and selective Brd2(2) ligand.Formula:C23H21N5O3Purity:98%Color and Shape:SolidMolecular weight:415.44SIRT6-IN-3
CAS:SIRT6-IN-3 (compound 8a), a selective SIRT6 inhibitor (IC50 = 7.49 μM), impedes the proliferation of pancreatic ductal adenocarcinoma (PDAC) cells and promptsFormula:C21H30Br3ClN6SPurity:98%Color and Shape:SolidMolecular weight:673.73PARP7-probe-1
CAS:PARP7-probe-1: biotinylated, chemiluminescent PARP7 active site probe for research use.Formula:C36H49F3N8O5SColor and Shape:SolidMolecular weight:762.89MS31
CAS:MS31 is a potent and highly affinity inhibitor of spindlin 1 (SPIN1).Formula:C20H27N3O2Purity:98%Color and Shape:SolidMolecular weight:341.45Tyk2-IN-9
CAS:Tyk2-IN-9: selective Tyk-2 inhibitor, IC50 of 0.076 nM (TYK2-JH2), 1.8 nM (JAK1-JH2), for inflammation/autoimmune research.Formula:C20H17N9Purity:98%Color and Shape:SolidMolecular weight:383.41MAK683-CH2CH2COOH
CAS:MAK683-CH2CH2COOH, an EED-targeting chemical, serves as a foundation for EED degrader-1 and PROTAC EED degrader-2 design.Formula:C23H21FN6O3Purity:98%Color and Shape:SolidMolecular weight:448.45Compound SA91-0178
CAS:SA91-0178 (3-{[(1-methyl-2-oxo-1'-phenyl-1,2-dihydrospiro[indole-3,4'-piperidine]-5-carbonyl)amino]methyl}benzoic acid) is a specific METTL1 inhibitor and effectively alleviated tissue injury during septic inflammation.Formula:C28H27N3O4Molecular weight:469.54GSK3368715 hydrochloride
CAS:GSK3368715, a first-in-class, orally active, potent, and selective SAM-noncompetitive inhibitor of Type I Protein Arginine Methyltransferases (PRMTs), exhibits anti-tumor efficacy across multiple cancer models and alters exon usage with IC50 values in the lower nM range. It synergizes with GSK3326595 (Type II inhibitor) (Axon 3750) to inhibit tumor growth.Formula:C20H38N4O2·HClColor and Shape:SolidMolecular weight:403MTDH-SND1 blocker 1
CAS:MTDH-SND1 Blocker 1 (Compound C26-A6) serves as an inhibitor targeting the MTDH-SND1 protein, effectively suppressing cancer metastasis [1].Formula:C14H13ClN4O3SColor and Shape:SolidMolecular weight:352.8
