Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2676 products for "Chromatin/Epigenetics".
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HDAC8-IN-6
HDAC8-IN-6 (compound 3) is a potent inhibitor of HDAC8 with an IC50 of 5.1 μM and exhibits cytotoxicity.Formula:C19H18IN3O2Color and Shape:SolidMolecular weight:447.04437Myelin Basic Protein
CAS:Myelin basic protein (MBP) is a protein believed to be important in the process of myelination of nerves in the nervous system.Formula:C60H103N21O17Purity:98%Color and Shape:SolidMolecular weight:1390.59iRucaparib-AP6
CAS:iRucaparib-AP6: a specific, non-trapping PARP1 degrader; inhibits the enzyme's activity and scaffolding.Formula:C46H55FN6O11Purity:98%Color and Shape:SolidMolecular weight:886.96PROTAC BRD4 Degrader-13
CAS:PROTAC BRD4 Degrader-13 targets VHL and BRD4, degrading BRD4 with DC50 of 0.025/6.0 nM in PC3 cells when linked to STEAP1/CLL1 antibodies.Formula:C68H85F2N11O17P2S2Color and Shape:SolidMolecular weight:1492.55MJ-26
MJ-26 is an inhibitor targeting Menin, characterized by a high binding affinity (Ki: 0.56 μM) and significant antiproliferative activity. It functions by inhibiting Menin-MLL interaction and promoting the degradation of Menin protein. MJ-26 demonstrates notable antitumor effects against acute myeloid leukemia (AML) and is applicable for AML research.INCB059872
CAS:INCB059872: potent, oral, selective LSD1 inhibitor for myeloid leukemia research.Formula:C23H34N2O3Color and Shape:SolidMolecular weight:386.536SYY-B085-1
CAS:SYY-B085-1 is a histone acetyltransferase (HAT) inhibitor.Formula:C27H23F4N5O4Color and Shape:SolidMolecular weight:557.506CD532 hydrochloride
CD532 hydrochloride, potent Aurora A inhibitor (IC50=45 nM), hampers MYCN protein, changes AURKA's shape, aids cancer research.Color and Shape:SolidTYK2 activator-1
TYK2activator-1 (16b) is a TYK2 activator with an EC50 value of 1.78 μM. It inhibits JAK2 and JAK3 with IC50 values of 6.8 μM and 6.3 μM, respectively.Formula:C23H21FN4O2Color and Shape:SolidMolecular weight:404.16485mUNO
CAS:mUNO is a tumor-homing peptide (mUNO, sequence: "CSPGAK") that specifically binds to murine CD206, targeting tumor-associated macrophages that express CD206/MRC1. Additionally, mUNO can interact with human recombinant CD206.Formula:C22H39N7O8SColor and Shape:SolidMolecular weight:561.652MS049 2HCl (1502816-23-0(free base))
MS049 inhibits PRMT4 (IC50=34nM) & PRMT6 (IC50=43nM), less so for PRMT1, PRMT3, PRMT8, not others.Formula:C15H26Cl2N2OPurity:99.9%Color and Shape:SolidMolecular weight:321.28PKC β pseudosubstrate
CAS:Selective cell-permeable peptide inhibitor of protein kinase C (IC50 ~ 0.5 μM).Formula:C177H294N62O38S3Purity:98%Color and Shape:SolidMolecular weight:3994.84Izilendustat
CAS:Tert-butyl compound inhibits human EGLN-1; confirmed by spectrometry after 20 mins.Formula:C22H28ClN3O4Purity:99.86%Color and Shape:White SolidMolecular weight:433.93BAY-184
CAS:BAY-184,KAT6A/B inhibitor (IC50=71/83 nM). Suppresses ERα activity. Impedes breast cancer proliferation.Formula:C23H20N2O4SPurity:98.87%Color and Shape:SolidMolecular weight:420.48Tazemetostat de(methylene morpholine)-O-C3-O-C-COOH
CAS:Tazemetostat de(methylene morpholine)-O-C3-O-C-COOH (Compound 21b), an EZH2 degrader, is employed in lymphoma research [1].Formula:C34H43N3O7Color and Shape:SolidMolecular weight:605.72pTH-Related Protein (1-40) (human, mouse, rat)
CAS:pTH-Related Protein (1-40) boosts rat calcium absorption via PTHR1 and PKCα/β. It up-regulates PTHR1, TRPV6, CaBP-D9k, NCX1, and PMCA1.Formula:C207H334N66O58Molecular weight:4675.27Casdatifan
CAS:Casdaitifan (AB521) is an orally active hypoxia inducible factor 2 alpha (HIF-2 alpha) inhibitor. Casdaitifan exhibits significant anti-tumor effects in the clear cell renal cell carcinoma (ccRCC) model.Formula:C21H17F4NO3SMolecular weight:439.42E67-2
CAS:E67-2: Low-toxic, KIAA1718 inhibitor with IC50 of 3.4μM, targets H3K9/H3K4 demethylases.Formula:C21H36N6O2Color and Shape:SolidMolecular weight:404.559ZL0590
CAS:ZL0590 is an effective and selective inhibitor of BD1-BRD4 (IC50 = 90 nM) with anti-inflammatory activities.Formula:C23H27F3N4O4SPurity:99.77%Color and Shape:SolidMolecular weight:512.55RK 286D
CAS:RK 286D is an indolocarbazole antibiotic.Formula:C26H23N3O4Color and Shape:SolidMolecular weight:441.48
