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Chromatin/Epigenetics

Chromatin/Epigenetics

Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.

Subcategories of "Chromatin/Epigenetics"

Found 2238 products of "Chromatin/Epigenetics"

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  • CCT 137690
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    CCT 137690

    CAS:
    <p>CCT 137690 is a highly specific and oral-available aurora kinase inhibitor, for aurora A(IC50=15 nM ), B(IC50=25 nM) and C(IC50=19 nM).</p>
    Formula:C26H31BrN8O
    Purity:98.51% - 99.89%
    Color and Shape:Solid
    Molecular weight:551.48

    Ref: TM-T2611

  • KW-2449
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    KW-2449

    CAS:
    <p>KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.</p>
    Formula:C20H20N4O
    Purity:98.43% - 99.69%
    Color and Shape:Solid
    Molecular weight:332.4

    Ref: TM-T2341

  • UNC0642
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    UNC0642

    CAS:
    <p>UNC0642 is an effective and specific G9a/GLP inhibitor (IC50&lt; 2.5 nM).</p>
    Formula:C29H44F2N6O2
    Purity:98.75% - 99.5%
    Color and Shape:Solid
    Molecular weight:546.7

    Ref: TM-T4166

  • BD750
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    BD750

    CAS:
    <p>BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 of 1.5 μM and 1.1 μM in</p>
    Formula:C14H13N3OS
    Purity:99.02%
    Color and Shape:Solid
    Molecular weight:271.34

    Ref: TM-T8546

  • BMS-911543
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    BMS-911543

    CAS:
    <p>BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2.</p>
    Formula:C23H28N8O
    Purity:97.69% - 99.98%
    Color and Shape:Solid
    Molecular weight:432.52

    Ref: TM-T6790

  • PARP1-IN-5 dihydrochloride 
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    PARP1-IN-5 dihydrochloride 

    CAS:
    <p>PARP1-IN-5 dihydrochloride: oral, potent PARP-1 inhibitor (IC50=14.7 nM), for cancer research.</p>
    Formula:C25H26Cl2N2O5S
    Purity:98.01%
    Color and Shape:Solid
    Molecular weight:537.46

    Ref: TM-T9610

  • GN44028
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    GN44028

    CAS:
    <p>GN44028 is a HIF-1 inhibitor with an IC50 of 14 nM, stopping HIF-1α activity but not mRNA or protein levels, or dimerization.</p>
    Formula:C18H15N3O2
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:305.33

    Ref: TM-T15396

  • Fedratinib hydrochloride hydrate
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    Fedratinib hydrochloride hydrate

    CAS:
    <p>Fedratinib hydrochloride hydrate (SAR 302503 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor.</p>
    Formula:C27H40Cl2N6O4S
    Purity:98.96% - 99.87%
    Color and Shape:Solid
    Molecular weight:615.61

    Ref: TM-T9251

  • PF-06651600 malonate
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    PF-06651600 malonate

    CAS:
    <p>PF-06651600 is a potent and selective JAK3 inhibitor.</p>
    Formula:C18H23N5O5
    Color and Shape:Solid
    Molecular weight:389.41

    Ref: TM-T5382L

  • WHI-P97
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    WHI-P97

    CAS:
    <p>WHI-P97 is a rationally designed potent inhibitor of JAK-3.</p>
    Formula:C16H13Br2N3O3
    Purity:99.93%
    Color and Shape:Solid
    Molecular weight:455.1

    Ref: TM-T4657

  • JQ-1 (carboxylic acid)
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    JQ-1 (carboxylic acid)

    CAS:
    <p>JQ-1 (carboxylic acid) is a cell-permeable BRD4 inhibitor with IC50s of 77 nM for BRD4(1) and 33 nM for BRD4(2)</p>
    Formula:C19H17ClN4O2S
    Purity:99.14% - 99.9%
    Color and Shape:Solid
    Molecular weight:400.88

    Ref: TM-T5443

  • Remodelin hydrobromide
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    Remodelin hydrobromide

    CAS:
    <p>Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.</p>
    Formula:C15H15BrN4S
    Purity:97.22% - 99.84%
    Color and Shape:Solid
    Molecular weight:363.275

    Ref: TM-T6133

  • SAR-20347
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    SAR-20347

    CAS:
    <p>SAR-20347 is an inhibitor of TYK2, JAK1/2/3 (IC50: 0.6/23/26/41 nM).</p>
    Formula:C21H18ClFN4O4
    Purity:98.99% - 99.77%
    Color and Shape:Solid
    Molecular weight:444.84

    Ref: TM-T4210

  • Hesperadin
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    Hesperadin

    CAS:
    <p>Hesperadin(IC50=250 nM) effectively inhibits Aurora B.</p>
    Formula:C29H32N4O3S
    Purity:98.04% - 99.44%
    Color and Shape:Solid
    Molecular weight:516.65

    Ref: TM-T6532

  • Rucaparib tartrate
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    Rucaparib tartrate

    CAS:
    <p>Rucaparib tartrate: oral PARP-1/2/3 inhibitor, Ki=1.4 nM; also inhibits H6PD; for studying CRPC.</p>
    Formula:C23H24FN3O7
    Color and Shape:Solid
    Molecular weight:473.457

    Ref: TM-T63065

  • PFI-3
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    PFI-3

    CAS:
    <p>PFI-3 is a selective chemical inhibitor for SMARCA (2/4) (Kd = 89 nM)and PBI (5) bromodomains which may result in the delay and prevention of breast cancer.</p>
    Formula:C19H19N3O2
    Purity:99.58% - 99.94%
    Color and Shape:Solid
    Molecular weight:321.37

    Ref: TM-T6939

  • PIN1 inhibitor API-1
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    PIN1 inhibitor API-1

    CAS:
    <p>API-1 is a Pin1 inhibitor (IC50: 72.3 nM), enhancing anticancer miRNA biogenesis and inhibiting hepatocellular carcinoma.</p>
    Formula:C15H13F3N6O2
    Purity:98.48%
    Color and Shape:Solid
    Molecular weight:366.3

    Ref: TM-T16538

  • 1,5-Isoquinolinediol
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    1,5-Isoquinolinediol

    CAS:
    <p>1,5-Isoquinolinediol, a PARP1 inhibitor (IC50: 0.39 μM), is used in DNA repair and cell death studies.</p>
    Formula:C9H7NO2
    Purity:98.29% - 99.35%
    Color and Shape:Of White To White Powder
    Molecular weight:161.16

    Ref: TM-T7042

  • UNC 669
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    UNC 669

    CAS:
    <p>UNC 669 is an effective and specific MBT (malignant brain tumor) inhibitor with IC50 of 4.2/3.1 uM for L3MBTL1/3.</p>
    Formula:C15H20BrN3O
    Purity:97.38%
    Color and Shape:Solid
    Molecular weight:338.24

    Ref: TM-T2252

  • UNC0646
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    UNC0646

    CAS:
    <p>UNC0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP with low cellular toxicity.</p>
    Formula:C36H59N7O2
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:621.9

    Ref: TM-TQ0232