Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2354 products of "Chromatin/Epigenetics"
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Aurora kinase inhibitor-2
CAS:<p>Aurora kinase inhibitor-2 (IUN-70219) is a cell-permeable anilinoquinazoline that inhibit the activity of Aurora A (IC50 = 0.39 M).</p>Formula:C23H20N4O3Purity:98.66%Color and Shape:SolidMolecular weight:400.43O-304
CAS:O-304 is a pan-activator of AMP-activated protein kinase (AMPK).Formula:C16H11Cl2N3O2SPurity:99.84% - ≥98%Color and Shape:SolidMolecular weight:380.252-hexyl-4-Pentynoic Acid
CAS:<p>2-hexyl-4-Pentynoic Acid, a valproic acid (VPA) derivatives, is a potent and robust HDACs inhibitor with IC50 value of 13 μM.</p>Formula:C11H18O2Purity:98%Color and Shape:SolidMolecular weight:182.26MRTX9768
CAS:<p>MRTX-9768 is a synthetic lethal-based inhibitor designed to bind the PRMT5-MTA complex and selectively target MTAP/CDKN2A-deleted tumors.</p>Formula:C24H17FN6OPurity:97.02%Color and Shape:SolidMolecular weight:424.43I-BET151
CAS:<p>I-BET151 (GSK1210151A) (GSK1210151A) is a specific BET inhibitor for BRD2/3/4 (IC50: 0.5/0.25/0.79 μM, in cell-free assays).</p>Formula:C23H21N5O3Purity:97.34% - 99.63%Color and Shape:SolidMolecular weight:415.44AS8351
CAS:AS8351 inhibits histone demethylase, used with various compounds to turn human lung fibroblasts into cardiomyocytes.Formula:C17H13N3O2Purity:99.54% - 99.72%Color and Shape:SolidMolecular weight:291.3MK-4827 Racemate
CAS:MK-4827 Racemate (Niraparib Racemate) is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity forFormula:C19H20N4OPurity:99.86%Color and Shape:SolidMolecular weight:320.394-Phenylbutyric acid
CAS:4-Phenylbutyric acid (Benzenebutyric acid) is a HDAC inhibitor and an endoplasmic reticulum stress (ERS) inhibitor. Cost-effective and quality-assured.Formula:C10H12O2Purity:98.40% - 99.76%Color and Shape:SolidMolecular weight:164.27BIO
CAS:<p>7BIO triggers nonapoptotic death, blocks FLT3, DYRK1A/2, Aurora B/C kinases.</p>Formula:C16H10BrN3O2Purity:99.67%Color and Shape:SolidMolecular weight:356.17SGI-1776
CAS:<p>SGI-1776 (Pim-Kinase Inhibitor IX) has been used in trials studying the treatment of Prostate Cancer, Non-Hodgkins Lymphoma, and Relapsed/Refractory Leukemias.</p>Formula:C20H22F3N5OPurity:99.3% - >99.99%Color and Shape:SolidMolecular weight:405.42NMS-P118
CAS:<p>NMS-P118 is a potent, selective and orally available Inhibitor of PARP-1 for cancer therapy.</p>Formula:C20H24F3N3O2Purity:98.79%Color and Shape:SolidMolecular weight:395.42Pamiparib
CAS:<p>Pamiparib (BGB-290) is an orally active, potent, highly selective PARP inhibitor. It has potent PARP trapping, and capability to penetrate the brain.</p>Formula:C16H15FN4OPurity:99.69%Color and Shape:SolidMolecular weight:298.31WDR5-0103 hydrochloride[890190-22-4(free base)]
<p>WDR5-0103 hydrochloride[890190-22-4(free base)] (WD-Repeat Protein 5-0103) is an effective and specific WD repeat-containing protein 5 (WDR5) antagonist (Kd:</p>Formula:C21H26ClN3O4Purity:99.66%Color and Shape:SolidMolecular weight:419.9UNC926
CAS:<p>UNC926 inhibits L3MBTL1 (IC50: 3.9 μM), has affinity for L3MBTL3, blocks 3xMBT-H4K20me1 interactions, doesn't affect 53BP1-H4K20me1 binding.</p>Formula:C16H21BrN2OPurity:97.22%Color and Shape:SolidMolecular weight:337.25Splitomicin
CAS:Splitomicin (1-Naphthalenepropanoic Acid) (IC50 of 60 μM), a specific inhibitor of NAD(+)-dependent histone deacetylase Sir2p, displays a high activity in aFormula:C13H10O2Purity:97.09% - 99.11%Color and Shape:SolidMolecular weight:198.22MLN8054 sodium
CAS:MLN8054 sodium is an Aurora A inhibitor.Formula:C25H14ClF2N4NaO2Color and Shape:SolidMolecular weight:498.84NVP-BSK805 trihydrochloride
CAS:<p>NVP-BSK805 trihydrochloride inhibits JAK2 (0.48 nM IC50); also affects JAK1, JAK3, TYK2.</p>Formula:C27H31Cl3F2N6OColor and Shape:SolidMolecular weight:599.933-TYP
CAS:<p>3-TYP (3-(1H-1,2,3-triazol-4-yl) pyridine) is a selective SIRT3 inhibitor.</p>Formula:C7H6N4Purity:99.16% - >99.99%Color and Shape:SolidMolecular weight:146.15BI-847325
CAS:BI-847325 is a selective dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively.Formula:C29H28N4O2Purity:97.13% - 97.54%Color and Shape:SolidMolecular weight:464.56YF-2
CAS:YF-2 activates histone acetyltransferases (H3, CBP, PCAF, GCN5) across the blood-brain barrier; EC50s: 2.75-49.31 μM.Formula:C20H22ClF3N2O3Purity:99.33%Color and Shape:SolidMolecular weight:430.85
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