Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2553 products of "Chromatin/Epigenetics"
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JAK-IN-14
CAS:JAK-IN-14 (compound 16) is a specific JAK1 inhibitor. It prevents JAK1 phosphorylation by binding to the active site of JAK in immune, inflammation and cancer.Formula:C19H15FN4OPurity:98.27%Color and Shape:SolidMolecular weight:334.35Ref: TM-T9764
1mg86.00€5mg180.00€10mg283.00€25mg587.00€50mg938.00€100mg1,491.00€200mg1,985.00€1mL*10mM (DMSO)188.00€PB131
CAS:PB131, a selective and brain-permeable HDAC6 inhibitor, exhibits high binding affinity (IC50: 1.8 nM) and potent anti-inflammatory activity, making it suitableFormula:C16H16FN3O2Purity:98%Color and Shape:SolidMolecular weight:301.32MPT0G211
CAS:MPT0G211: oral HDAC6 inhibitor with IC50=0.291 nM, 1000x selectivity, neuroprotective, anti-metastatic, crosses blood-brain barrier for Alzheimer's.Formula:C17H15N3O2Purity:99.93% - 99.98%Color and Shape:SolidMolecular weight:293.32Ref: TM-T60616
1mg92.00€5mg222.00€10mg356.00€25mg560.00€50mg782.00€100mg1,063.00€200mg1,459.00€1mL*10mM (DMSO)245.00€GS-626510
CAS:GS-626510 is an orally bioavailable inhibitor of BET family bromodomains (Kd: 0.59-3.2 nM for BRD2/3/4; IC50: 83 nM and 78 nM for BD1 and BD2).Formula:C25H22N4OColor and Shape:SolidMolecular weight:394.47IDO1 and HDAC1 Inhibitor
CAS:IDO1 and HDAC1 Inhibitor is a dual IDO1 and HDAC1 inhibitor (IC50s: 69.0 nM and 66.5 nM).Formula:C25H22BrFN8O4Purity:98%Color and Shape:SolidMolecular weight:597.4Exifone
CAS:Exifone (NSC-680919) is a mixed, nonessential activator of HDAC1 that is capable of binding to both free and substrate-bound enzyme, resulting in an increasedFormula:C13H10O7Purity:99.77% - 99.95%Color and Shape:Yellow SolidMolecular weight:278.21HDAC-IN-49
HDAC-IN-49: potent, broad HDAC inhibitor; IC50s: 10-1880 nM for HDAC1-6; strong anti-leukemic, low toxicity to healthy cells.Formula:C26H27FN4O4Color and Shape:SolidMolecular weight:478.52Sirt1/2-IN-1
CAS:Sirt1/2-IN-1 inhibits SIRT1 (IC50: 1.81 μg/mL) and SIRT2 (2.10 μg/mL), less on SIRT3 (20.5 μg/mL), with anticancer properties.Formula:C22H13ClN2OS2Color and Shape:SolidMolecular weight:420.932′-Deoxy-5-nitrocytidine
CAS:2′-Deoxy-5-nitrocytidine is a DNA Methyltransferase inhibitor that can be used for cancer research[1].Formula:C9H12N4O6Color and Shape:SolidMolecular weight:272.21SB-284851-BT
CAS:SB-284851-BT: BRD4/p38α/BRDT inhibitor; IC50: BRD4-BD1 1.7µM, BRDT 18µM, BRD4 3.7µM; Kd p38α 0.47nM; reduces IL-8, affects c-Myc/NF-κB.Formula:C26H26FN5OColor and Shape:SolidMolecular weight:443.52PKC-IN-4
CAS:PKC-IN-4 (compound 7l) is a highly potent and orally active inhibitor of atypical protein kinase C (aPKC), exhibiting an IC 50 value of 0.52 μM.Formula:C21H25N5SColor and Shape:SolidMolecular weight:379.52CD161
CAS:CD161: powerful, selective oral BET inhibitor; IC50: 28.2 nM (BRD4 BD1), 7.2 nM (BRD4 BD2); strong anticancer properties.Formula:C26H21N5O2Purity:98%Color and Shape:SolidMolecular weight:435.48KDM5A-IN-1
CAS:KDM5A-IN-1 is a pan-histidine lysine demethylase 5 KDM5 inhibitor that inhibits KDM5A, KDM5B, and KDM5C.Can be used in the study of cancer.Formula:C15H22N4O2Purity:>99.99%Color and Shape:SolidMolecular weight:290.36DC_517
CAS:DC_517 is an inhibitor of DNA methyltransferase 1 (DNMT1) ( IC50: 1.7 μM; Kd: 0.91 μM).Formula:C33H35N3O2Color and Shape:SolidMolecular weight:505.65L 888607 Racemate
CAS:L 888607 Racemate blocks DP1 and TP receptors with 132 nM and 17 nM affinity.Formula:C19H15ClFNO2SColor and Shape:SolidMolecular weight:375.84YF479
CAS:YF479 is an inhibitor of histone deacetylase that acts by inhibiting breast tumor growth, metastasis, and recurrence.Formula:C22H27BrN2O5Purity:98%Color and Shape:SolidMolecular weight:479.36PS315
CAS:PS315, a PS48 derivative, allosterically inhibits PKCζ/η (IC50: 10/30 μM), targeting aPKC's PIF-pocket, with anti-cancer properties.Formula:C23H19ClO2Purity:98%Color and Shape:SolidMolecular weight:362.85DC-CPin7
CAS:DC-CPin7, a powerful inhibitor of the bromodomain of CREB-binding protein (CBP), exhibits an IC50 value of 2.5 μM [1].Formula:C19H22N2O5Color and Shape:SolidMolecular weight:358.39Ilorasertib hydrochloride
CAS:Ilorasertib hydrochloride (ABT-348 hydrochloride) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A (IC50s:Formula:C25H22ClFN6O2SPurity:98.45%Color and Shape:SolidMolecular weight:525Tetrahydrouridine
CAS:Tetrahydrouridine (NSC-112907; THU) is a multidrug resistance modulator.Formula:C9H16N2O6Purity:98%Color and Shape:SolidMolecular weight:248.23
