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Thyroid hormone receptor(THR)

Thyroid hormone receptor(THR)

Thyroid hormone receptors (THRs) are nuclear receptors that mediate the effects of thyroid hormones, which are critical for regulating metabolism, growth, and development. Modulation of THR activity is important in the treatment of thyroid disorders, metabolic syndromes, and certain cancers. THR agonists and antagonists are used in research to study the physiological and pathological roles of thyroid hormones. At CymitQuimica, we offer a wide range of high-quality thyroid hormone receptor modulators to support your research in endocrinology, metabolism, and hormone regulation.

Found 26 products of "Thyroid hormone receptor(THR)"

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  • TR antagonist 1
    Targetmol
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    TR antagonist 1

    CAS:
    <p>TR antagonist 1 is a highly potent thyroid hormone receptor (TR) antagonist that can be used to study diseases caused by endocrine abnormalities.</p>
    Formula:C25H23Br2NO4
    Purity:99.57%
    Color and Shape:Solid
    Molecular weight:561.26

    Ref: TM-T13435

  • MB-07344
    Targetmol
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    MB-07344

    CAS:
    <p>MB-07344 is a selective THR-β (thyroid hormone receptor β) agonist with a Ki of 2.17 nM, capable of reducing plasma total cholesterol (TPC).</p>
    Formula:C19H25O5P
    Purity:99.32%
    Color and Shape:Solid
    Molecular weight:364.37

    Ref: TM-T11954

  • DS08210767
    Targetmol
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    DS08210767

    CAS:
    <p>DS08210767 is a highly potent, orally bioavailable PTHR1 antagonist with IC50 of 90 nM.</p>
    Formula:C31H39N5O2
    Purity:98.79%
    Color and Shape:Solid
    Molecular weight:513.67

    Ref: TM-T11101

  • MB-07811
    Targetmol
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    MB-07811

    CAS:
    <p>MB-07811 (VK-2809) is an orally active HepDirect prodrug of MB07344 with cholesterol and triglycerides lowering activity.</p>
    Formula:C28H32ClO5P
    Purity:99.74% - 99.94%
    Color and Shape:Solid
    Molecular weight:514.98

    Ref: TM-T16018

  • CO23
    Targetmol
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    CO23

    CAS:
    <p>CO23 is a blood-brain barrier penetrant and selective TRα agonist and can be used in studies about the regulation of growth and development.</p>
    Formula:C19H18I2N2O4
    Purity:98.08%
    Color and Shape:Solid
    Molecular weight:592.17

    Ref: TM-T10855

  • MLS000389544
    Targetmol
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    MLS000389544

    CAS:
    <p>MLS000389544 is a selective and potent thyroid hormone receptor β (TRβ) antagonist with a methylsulfonyl nitrobenzoic acid structure. It effectively inhibits the interaction between TRβ and steroid receptor coactivator 2 (SRC2).</p>
    Formula:C20H24N2O7S
    Color and Shape:Solid
    Molecular weight:436.479

    Ref: TM-T204954