Thyroid hormone receptor(THR)
Thyroid hormone receptors (THRs) are nuclear receptors that mediate the effects of thyroid hormones, which are critical for regulating metabolism, growth, and development. Modulation of THR activity is important in the treatment of thyroid disorders, metabolic syndromes, and certain cancers. THR agonists and antagonists are used in research to study the physiological and pathological roles of thyroid hormones. At CymitQuimica, we offer a wide range of high-quality thyroid hormone receptor modulators to support your research in endocrinology, metabolism, and hormone regulation.
Found 34 products of "Thyroid hormone receptor(THR)"
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Resmetirom
CAS:Resmetirom (MGL-3196) is a THR-β agonist (EC50=0.21 μM), with high selectivity and oral activity. High-Quality, Low-Cost!Formula:C17H12Cl2N6O4Purity:99.05% - >99.99%Color and Shape:SolidMolecular weight:435.22Ref: TM-T3595
1mg37.00€2mg49.00€1mL*10mM (DMSO)87.00€5mg93.00€10mg119.00€25mg202.00€50mg324.00€100mg482.00€500mg1,071.00€Sobetirome
CAS:Sobetirome (IACS-010759) is a selective agonist of thyroid hormone receptor β (TRβ) and binds selectively to TRβ-1 (EC50: 0.16 μM).Formula:C20H24O4Purity:98.08% - 98.25%Color and Shape:SolidMolecular weight:328.4(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate
D-Trp12,Tyr34-pTH(7-34) (bovine) is a PTH antagonist with a Ki of 69 nM in bovine kidneys.Purity:96.84%Color and Shape:LiquidMolecular weight:N/ADPC AJ1951 acetate
DPC-AJ1951 acetate: 14-amino acid peptide, potent PTH/PPR agonist, tested for bone resorption activity ex vivo/in vivo.Formula:C78H131N23O21Purity:96.63%Color and Shape:SolidMolecular weight:1727.023,3',5-Triiodothyronine-(tyrosine ring-13C6)
CAS:3,3',5-Triiodothyronine-(tyrosine ring-13C6) is the 13C labeled compound of 3,3',5-Triiodothyronine. 3,3',5-Triiodothyronine has a CAS number of 5817-39-0.
Formula:C4C11H12I3NO4Color and Shape:SolidMolecular weight:656.93KAT681
CAS:KAT681 is a liver selective thyromimetic.Formula:C24H22FNNaO6Purity:98%Color and Shape:SolidMolecular weight:462.429Azetirelin
CAS:Azetirelin, as a TRH analog, has a more potent effect than TRH on the central nervous system.Formula:C15H20N6O4Purity:99.72%Color and Shape:SolidMolecular weight:348.36Glutaurine aceate
Glutaurine aceate containing glutamine and taurine residues is an orally active hormone of the parathyroid.Formula:C9H18N2O8SPurity:98%Color and Shape:SoildMolecular weight:314.31TR antagonist 1
CAS:TR antagonist 1 is a highly potent thyroid hormone receptor (TR) antagonist that can be used to study diseases caused by endocrine abnormalities.Formula:C25H23Br2NO4Purity:99.57%Color and Shape:SolidMolecular weight:561.26MB-07344
CAS:MB-07344 is a selective THR-β (thyroid hormone receptor β) agonist with a Ki of 2.17 nM, capable of reducing plasma total cholesterol (TPC).Formula:C19H25O5PPurity:99.32%Color and Shape:SolidMolecular weight:364.37CO23
CAS:CO23 is a blood-brain barrier penetrant and selective TRα agonist and can be used in studies about the regulation of growth and development.Formula:C19H18I2N2O4Purity:98.08%Color and Shape:SolidMolecular weight:592.17DS08210767
CAS:DS08210767 is a highly potent, orally bioavailable PTHR1 antagonist with IC50 of 90 nM.Formula:C31H39N5O2Purity:98.79%Color and Shape:SolidMolecular weight:513.67MB-07811
CAS:MB-07811 (VK-2809) is an orally active HepDirect prodrug of MB07344 with cholesterol and triglycerides lowering activity.Formula:C28H32ClO5PPurity:99.74% - 99.94%Color and Shape:SolidMolecular weight:514.98MLS000389544
CAS:MLS000389544 is a selective and potent thyroid hormone receptor β (TRβ) antagonist with a methylsulfonyl nitrobenzoic acid structure. It effectively inhibits the interaction between TRβ and steroid receptor coactivator 2 (SRC2).Formula:C20H24N2O7SColor and Shape:SolidMolecular weight:436.479
