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Reductase

Reductase

Reductases are a broad class of enzymes that catalyze the reduction of molecules in various biochemical pathways. In endocrinology, specific reductases, such as 5α-reductase, are crucial for the metabolism of steroid hormones, including the conversion of testosterone to dihydrotestosterone (DHT). Inhibitors of reductase enzymes are used in the treatment of conditions like benign prostatic hyperplasia and androgenic alopecia. At CymitQuimica, we offer a variety of high-quality reductase inhibitors to support your research in hormone regulation, metabolic pathways, and therapeutic development.

Found 52 products of "Reductase"

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  • Zenarestat
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    Zenarestat

    CAS:
    <p>Zenarestat is an orally active aldose reductase inhibitor capable of ameliorating diabetic peripheral neuropathy in rats with type 2 diabetes.</p>
    Formula:C17H11BrClFN2O4
    Purity:99.51% - 99.51%
    Color and Shape:Solid
    Molecular weight:441.64

    Ref: TM-T35299

  • 6-Hydroxyluteolin
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    6-Hydroxyluteolin

    CAS:
    <p>6-Hydroxyluteolin, a flavonoid compound extracted from Salvia amarissima Ortega, inhibits aldose reductase (AR) and has antimicrobial activity.</p>
    Formula:C15H10O7
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:302.24

    Ref: TM-T79005

  • AY 9944
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    AY 9944

    CAS:
    <p>AY 9944 inhibits DHCR7 enzyme (IC50=13 nM) and sterol isomerase, leading to hypocholesterolemia and 7DHC buildup.</p>
    Formula:C22H30Cl4N2
    Purity:98.92% - 99.65%
    Color and Shape:Solid
    Molecular weight:464.3

    Ref: TM-T14362

  • Izonsteride
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    Izonsteride

    CAS:
    <p>Izonsteride (LY320236) is a selective and potent 5alpha reductase inhibitor with dual action on the type I and type II isoforms of the enzyme.Izonsteride is</p>
    Formula:C24H26N2OS2
    Purity:99.55%
    Color and Shape:Solid
    Molecular weight:422.61

    Ref: TM-T27643

  • Lidorestat
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    Lidorestat

    CAS:
    <p>Lidorestat (IDD-676) is an aldose reductase inhibitor (IC50: 5 nM) with effective, selective and oral activity.</p>
    Formula:C18H11F3N2O2S
    Purity:99.98%
    Color and Shape:Solid
    Molecular weight:376.35

    Ref: TM-T15756

  • Caracemide
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    Caracemide

    CAS:
    <p>Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.</p>
    Formula:C6H11N3O4
    Purity:99.8%
    Color and Shape:Solid
    Molecular weight:189.17

    Ref: TM-T14864

  • Minalrestat
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    Minalrestat

    CAS:
    <p>Minalrestat(ARI-509) is an orally active and potent aldose reductase inhibitor for the study of impaired microvascular reactivity in diabetic patients.</p>
    Formula:C19H11BrF2N2O4
    Purity:98.64% - 99.88%
    Color and Shape:Solid
    Molecular weight:449.2

    Ref: TM-T33389

  • Zopolrestat
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    Zopolrestat

    CAS:
    <p>Zopolrestat (CP 73850) is a potent inhibitor of aldose reductase (IC50 = 3.1 nM).</p>
    Formula:C19H12F3N3O3S
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:419.38

    Ref: TM-T35317

  • Ranirestat
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    Ranirestat

    CAS:
    <p>Ranirestat (AS-3201) is an AR inhibitor with neuroprotective properties that improves peripheral nerve dysfunction in rats with advanced diabetic polyneuropathy</p>
    Formula:C17H11BrFN3O4
    Purity:98.83% - 99.44%
    Color and Shape:Solid
    Molecular weight:420.19

    Ref: TM-T16723

  • RJG-2051
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    RJG-2051

    CAS:
    <p>RJG-2051 is a selective covalent inhibitor of aldo-keto reductase family 1 member C3 (AKR1C3), with an IC50 value of 13 nM. It interferes with the metabolism of substrates such as androgens, estrogens, and prostaglandins through AKR1C3. RJG-2051 holds potential for cancer research.</p>
    Formula:C26H31N5O4S
    Color and Shape:Solid
    Molecular weight:509.62

    Ref: TM-T206799

  • (Rac)-Fidarestat
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    (Rac)-Fidarestat

    CAS:
    <p>(Rac)-Fidarestat ((Rac)-SNK 860) is the racemic form of Fidarestat, functioning as a potent inhibitor of the enzyme aldose reductase.</p>
    Formula:C12H10FN3O4
    Color and Shape:Solid
    Molecular weight:279.224

    Ref: TM-T207035

  • NSC 645827
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    NSC 645827

    CAS:
    <p>NSC 645827 is an inhibitor of NAD(P)H:quinone oxidoreductase 1 (NQO1), with an IC50 of 0.7 μM.</p>
    Formula:C17H17N5O2
    Color and Shape:Solid
    Molecular weight:323.349

    Ref: TM-T204942