Reductase
Reductases are a broad class of enzymes that catalyze the reduction of molecules in various biochemical pathways. In endocrinology, specific reductases, such as 5α-reductase, are crucial for the metabolism of steroid hormones, including the conversion of testosterone to dihydrotestosterone (DHT). Inhibitors of reductase enzymes are used in the treatment of conditions like benign prostatic hyperplasia and androgenic alopecia. At CymitQuimica, we offer a variety of high-quality reductase inhibitors to support your research in hormone regulation, metabolic pathways, and therapeutic development.
Found 58 products for "Reductase".
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Risarestat
CAS:Risarestat (CT-112) is a potent aldose reductase inhibitor and thyroid hormone receptor (TR) antagonist for the treatment of hypoglycemia.Formula:C16H21NO4SPurity:98.39%Color and Shape:SolidMolecular weight:323.407Zenarestat
CAS:Zenarestat is an orally active aldose reductase inhibitor capable of ameliorating diabetic peripheral neuropathy in rats with type 2 diabetes.Formula:C17H11BrClFN2O4Purity:99.51% - 99.51%Color and Shape:White SolidMolecular weight:441.636SN34037
CAS:SN34037, specific Aldo-keto reductase 1C3 (AKR1C3) inhibitor, inhibiting the cytotoxic activity of PR-104A, suitable for studying PR-104A-responsive leukaemia.Formula:C15H19Cl2N3O2Purity:99.03%Color and Shape:Yellow SolidMolecular weight:344.24Aldose reductase-IN-6
CAS:Aldose reductase-IN-6 is an AR inhibitor; blocks polyol pathway; reduces sorbitol; diabetic complications research tool.Formula:C20H16N4O2SPurity:99.63%Color and Shape:White SolidMolecular weight:376.43AY 9944
CAS:AY 9944 inhibits DHCR7 enzyme (IC50=13 nM) and sterol isomerase, leading to hypocholesterolemia and 7DHC buildup.Formula:C22H30Cl4N2Purity:98.92% - 99.65%Color and Shape:White SolidMolecular weight:464.3Fidarestat
CAS:Fidarestat (SNK 860),Aldose reductase inhibitor (IC50=26 nM). Targets AKR1B10 (33 μM) and V301L AKR1B10 (1.8 μM). Potential diabetes treatment.Formula:C12H10FN3O4Purity:98%Color and Shape:White SolidMolecular weight:279.2239Izonsteride
CAS:Izonsteride (LY320236) is a selective and potent 5alpha reductase inhibitor with dual action on the type I and type II isoforms of the enzyme.Izonsteride isFormula:C24H26N2OS2Purity:99.5%Color and Shape:SolidMolecular weight:422.606Lidorestat
CAS:Lidorestat (IDD-676) is an aldose reductase inhibitor (IC50: 5 nM) with effective, selective and oral activity.Formula:C18H11F3N2O2SPurity:99.98%Color and Shape:SolidMolecular weight:376.352Caracemide
CAS:Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.Formula:C6H11N3O4Purity:99.8%Color and Shape:SolidMolecular weight:189.1692Minalrestat
CAS:Minalrestat(ARI-509) is an orally active and potent aldose reductase inhibitor for the study of impaired microvascular reactivity in diabetic patients.Formula:C19H11BrF2N2O4Purity:98.64% - 99.88%Color and Shape:SolidMolecular weight:449.2Zopolrestat
CAS:Zopolrestat (CP 73850) is a potent inhibitor of aldose reductase (IC50 = 3.1 nM).Formula:C19H12F3N3O3SPurity:99.74% - 99.82%Color and Shape:SolidMolecular weight:419.377Ranirestat
CAS:Ranirestat (AS-3201) is an AR inhibitor with neuroprotective properties that improves peripheral nerve dysfunction in rats with advanced diabetic polyneuropathyFormula:C17H11BrFN3O4Purity:96.10% - 99.44%Color and Shape:SolidMolecular weight:420.189N-(3-Methylphenyl)anthranilic acid
CAS:N-(3-Methylphenyl)anthranilic acid is an inhibitor of aldo-keto reductase 1C3 (AKR1C3) and AKR1C2 with IC50 values of 0.24 μM and 0.38 μM, respectively. It does not inhibit COX-1 or COX-2. This compound can be utilized in research on castration-resistant prostate cancer.Formula:C14H13NO2Molecular weight:227.2585(Rac)-Fidarestat
CAS:(Rac)-Fidarestat ((Rac)-SNK 860) is the racemic form of Fidarestat, functioning as a potent inhibitor of the enzyme aldose reductase.Formula:C12H10FN3O4Color and Shape:SolidMolecular weight:279.224NSC 645827
CAS:NSC 645827 is an inhibitor of NAD(P)H:quinone oxidoreductase 1 (NQO1), with an IC50 of 0.7 μM.Formula:C17H17N5O2Color and Shape:SolidMolecular weight:323.349ALR2-IN-7
CAS:ALR2-IN-7 (Compound 5a) is a potent and selective inhibitor of alditol reductase (ALR2/AKR1B1) with a Ki of 8.71 nM. It holds potential for research into diabetic complications such as retinopathy and nephropathy, as well as cancer.Formula:C17H15NO3Color and Shape:SolidMolecular weight:281.3059RJG-2051
CAS:RJG-2051 is a selective covalent inhibitor of aldo-keto reductase family 1 member C3 (AKR1C3), with an IC50 value of 13 nM. It interferes with the metabolism of substrates such as androgens, estrogens, and prostaglandins through AKR1C3. RJG-2051 holds potential for cancer research.Formula:C26H31N5O4SColor and Shape:SolidMolecular weight:509.62ALR2-IN-10
CAS:ALR2-IN-10 (Compound 23) is a weak inhibitor of aldose reductase 2 (Aldose Reductase2), showing an inhibition rate of 6% at a concentration of 27 μM. It is applicable in research related to diabetic complications.Formula:C21H15NO2Molecular weight:313.3493
