CymitQuimica logo
NF-κB

NF-κB

Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.

Found 445 products of "NF-κB"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • Betulinic acid
    Targetmol
    + Info

    Betulinic acid

    CAS:
    <p>Betulinic acid, a lupane-type triterpene from white birch bark, has antiretroviral, antimalarial, anti-inflammatory, and anticancer properties.</p>
    Formula:C30H48O3
    Purity:99.12% - 99.7%
    Color and Shape:White Crystalline Powder
    Molecular weight:456.7

    Ref: TM-T2830

  • Indacaterol
    Targetmol
    + Info

    Indacaterol

    CAS:
    <p>Indacaterol (Onbrez; Arcapta) is a β2-Adrenergic Agonist. The mechanism of action of indacaterol is as an Adrenergic beta2-Agonist.</p>
    Formula:C24H28N2O3
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:392.49

    Ref: TM-T2320

  • Rucaparib monocamsylate
    Targetmol
    + Info

    Rucaparib monocamsylate

    CAS:
    <p>Rucaparib monocamsylate (Rucaparib Camsylate) is a PARP inhibitor. Rucaparib Camsylate also displays binding affinity to eight other PARP domains.</p>
    Formula:C29H34FN3O5S
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:555.66

    Ref: TM-T16807

  • Tryptanthrin
    Targetmol
    + Info

    Tryptanthrin

    CAS:
    <p>Tryptanthrin is a natural DNA gyrase inhibitor.</p>
    Formula:C15H8N2O2
    Purity:99.64% - 99.94%
    Color and Shape:Solid
    Molecular weight:248.24

    Ref: TM-T7786

  • Sauchinone
    Targetmol
    + Info

    Sauchinone

    CAS:
    <p>Sauchinone: Treats infections, prevents liver fibrosis, reduces oxidative stress, and protects skin and vascular cells.</p>
    Formula:C20H20O6
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:356.37

    Ref: TM-T6S1572

  • GSK547
    Targetmol
    + Info

    GSK547

    CAS:
    <p>GSK547 (GSK'547) is a highly selective and potent inhibitor of RIP1 kinase,inhibits macrophage-mediated adaptive immune tolerance in pancreatic cancer.</p>
    Formula:C20H18F2N6O
    Purity:99.17%
    Color and Shape:Solid
    Molecular weight:396.39

    Ref: TM-T7397

  • Sanggenon C
    Targetmol
    + Info

    Sanggenon C

    CAS:
    <p>Sanggenon C inhibits NF-κB activity, the expression of inducible nitric oxide synthase, tumor necrosis factor-α-stimulated cell adhesion and the expression of vascular cell adhesion molecule-1 in RAW264.7 cells. Cost-effective and quality-assured.</p>
    Formula:C40H36O12
    Purity:97.76% - 99.76%
    Color and Shape:Solid
    Molecular weight:708.71

    Ref: TM-T4S1615

  • HOMOPLANTAGININ
    Targetmol
    + Info

    HOMOPLANTAGININ

    CAS:
    <p>Homoplantaginin is a flavonoid from a traditional Chinese medicine Salvia plebeia,it has a protective and therapeutic effect on hepatocyte injury and shows</p>
    Formula:C22H22O11
    Purity:97.63% - 99.66%
    Color and Shape:Solid
    Molecular weight:462.4

    Ref: TM-T4S0217

  • SC75741
    Targetmol
    + Info

    SC75741

    CAS:
    <p>SC75741 is a potent P65 inhibitor with IC50 of 200 nM</p>
    Formula:C29H23N7O2S2
    Purity:99.44% - 99.54%
    Color and Shape:Solid
    Molecular weight:565.67

    Ref: TM-T6661

  • Sulforaphene
    Targetmol
    + Info

    Sulforaphene

    CAS:
    <p>Sulforaphene, from radish seeds, aids cancer cell apoptosis and inhibits migration; has an ED50 for velvetleaf at ~2x10^-4 M.</p>
    Formula:C6H9NOS2
    Purity:97.55% - 99.19%
    Color and Shape:Slightly Yellowish Liquid
    Molecular weight:175.27

    Ref: TM-TL0016

  • Ginsenoside Rg5
    Targetmol
    + Info

    Ginsenoside Rg5

    CAS:
    <p>Ginsenoside Rg5 shows promise for Alzheimer's, reduces inflammation, and aids vascular health without side effects.</p>
    Formula:C42H70O12
    Purity:98% - 99.65%
    Color and Shape:Solid
    Molecular weight:767

    Ref: TM-T6S1487

  • WAY-169916
    Targetmol
    + Info

    WAY-169916

    CAS:
    <p>WAY-169916 inhibits ER by blocking NF-kB activity, lacks estrogenic effects.</p>
    Formula:C17H13F3N2O2
    Purity:98.63% - 98.64%
    Color and Shape:Solid
    Molecular weight:334.29

    Ref: TM-T8981

  • Astilbin
    Targetmol
    + Info

    Astilbin

    CAS:
    <p>Astilbin (Neoastilbin) is actions Flavonoid phytochemical found in St. John′s wort and Traditional Chinese Medicine herbal preparations.</p>
    Formula:C21H22O11
    Purity:97% - 99.86%
    Color and Shape:White Powder
    Molecular weight:450.39

    Ref: TM-T2794

  • Praeruptorin A
    Targetmol
    + Info

    Praeruptorin A

    CAS:
    <p>Praeruptorin A ((+)-Praeruptorin A) has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin</p>
    Formula:C21H22O7
    Purity:99.63% - 99.65%
    Color and Shape:Solid
    Molecular weight:386.4

    Ref: TM-T3777

  • Tenuigenin
    Targetmol
    + Info

    Tenuigenin

    CAS:
    <p>Tenuigenin (Senegenin) is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and anti-inflammatory activity.</p>
    Formula:C30H45ClO6
    Purity:98.9% - 99.53%
    Color and Shape:Solid
    Molecular weight:537.13

    Ref: TM-T3907

  • Tectochrysin
    Targetmol
    + Info

    Tectochrysin

    CAS:
    <p>Tectochrysin: antioxidant, hinders ABCG2 transport, induces apoptosis in NSC-LC by blocking STAT3 and activating DR3/Fas.</p>
    Formula:C16H12O4
    Purity:99.26%
    Color and Shape:Solid
    Molecular weight:268.26

    Ref: TM-T3S1775

  • INH14
    Targetmol
    + Info

    INH14

    CAS:
    <p>INH14 is a novel inhibitor of the IKKα/β-dependent TLR inflammatory response (IC50s: 8.97/3.59 μM for IKKα/IKKβ).</p>
    Formula:C15H16N2O
    Purity:95.41%
    Color and Shape:Solid
    Molecular weight:240.3

    Ref: TM-T5209

  • Picroside II
    Targetmol
    + Info

    Picroside II

    CAS:
    <p>Picroside II (Vanilloyl catalpol) is the main active ingredient in iridoid glycosides.</p>
    Formula:C23H28O13
    Purity:98% - 99.83%
    Color and Shape:Solid
    Molecular weight:512.46

    Ref: TM-T2817

  • Phorbol 12-myristate 13-acetate
    Targetmol
    + Info

    Phorbol 12-myristate 13-acetate

    CAS:
    <p>Phorbol 12-myristate 13-acetate (PMA) belongs to the phorbol ester group of natural products and is an activator of PKC, SphK, and NF-κB.</p>
    Formula:C36H56O8
    Purity:98.55% - >99.99%
    Color and Shape:White To Off-White Solid
    Molecular weight:616.83

    Ref: TM-TQ0198

  • Handelin
    Targetmol
    + Info

    Handelin

    CAS:
    <p>Handelin has anti-inflammatory activity by inhibiting NF-κB activation and pro-inflammatory cytokine productions.</p>
    Formula:C32H40O8
    Purity:99.02% - 99.345%
    Color and Shape:Solid
    Molecular weight:552.66

    Ref: TM-TN1131