NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
Found 390 products of "NF-κB"
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Isodeoxyelephantopin
CAS:Isodeoxyelephantopin can inhibit the growth of various tumor cells.Formula:C19H20O6Purity:99.88%Color and Shape:SolidMolecular weight:344.36IKKγ NBD Inhibitory Peptide acetate
IKKγ NBD Inhibitory Peptide acetate is a NEMO-binding domain peptide (NBD peptide) acetate corresponding to the NEMO amino-terminal alpha-helical region.
Purity:99.15%Color and Shape:SolidMolecular weight:N/ARef: TM-TP1615L
1mg131.00€2mg173.00€5mg255.00€10mg374.00€25mg625.00€50mg890.00€100mg1,206.00€500mg2,422.00€Vamorolone
CAS:Vamorolone (VBP15) is a steroid-like drug that treats muscular dystrophy with fewer side effects and inhibits NF-κB.Formula:C22H28O4Purity:99.54%Color and Shape:SolidMolecular weight:356.46Ref: TM-T17217
1mg34.00€2mg49.00€5mg74.00€10mg105.00€25mg178.00€50mg281.00€100mg421.00€200mg605.00€1mL*10mM (DMSO)82.00€Robinin
CAS:Robinin: a kaempferol-derived flavone glycoside with antibacterial, diuretic traits; minimal effect on Colo 320 MDR1/LRP resistance; detected in MCF-7 cells.Formula:C33H40O19Purity:98.78% - 99.13%Color and Shape:SolidMolecular weight:740.66Polygalasaponin F
CAS:Polygalasaponin F reduces neuroinflammation, blocks TNF-α/NO, and protects neurons by modulating NF-kB and NMDAR pathways.Formula:C53H86O23Purity:98% - 99.83%Color and Shape:SolidMolecular weight:1091.24Embelin
CAS:Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).Formula:C17H26O4Purity:97.07% - 99.88%Color and Shape:SolidMolecular weight:294.39Triptolide
CAS:Triptolide (PG490) belongs to the tricyclic diterpenoid group of natural products and is an inhibitor of NF-κB activation.Formula:C20H24O6Purity:97.19% - 99.97%Color and Shape:White To Off-White SolidMolecular weight:360.40Ref: TM-T2179
1mg39.00€2mg52.00€5mg95.00€10mg123.00€25mg225.00€50mg315.00€100mg444.00€1mL*10mM (DMSO)75.00€Barlerin
CAS:Barlerin (8-O-Acetylshanzhiside methyl ester) has potential against cerebral ischemic injury, and protective effect on oxygen-glucose deprivation-induced injuryFormula:C19H28O12Purity:99.83% - ≥95%Color and Shape:SolidMolecular weight:448.42Ref: TM-T5S1632
1mg38.00€2mg50.00€5mg80.00€10mg109.00€25mg231.00€50mg335.00€100mg505.00€1mL*10mM (DMSO)87.00€TBK1/IKKε-IN-5
CAS:TBK1/IKKε-IN-5 is a dual TBK1 and IKKε inhibitor(IC50 of 1 nM and 5.6 nM, respectively).Formula:C28H31N7O3Purity:98.77%Color and Shape:SolidMolecular weight:513.59Ref: TM-T7951
1mg88.00€5mg182.00€10mg269.00€25mg429.00€50mg587.00€100mg837.00€200mg1,125.00€1mL*10mM (DMSO)224.00€Mollugin
CAS:Mollugin could be a JAK2 inhibitor, anti-inflammatory, chemotherapeutic agent in OSCCs, bone disorder therapy, and modulates HER2 in cancer.Formula:C17H16O4Purity:99.87% - ≥95%Color and Shape:SolidMolecular weight:284.31Tyrosol
CAS:Tyrosol (2-(4-Hydroxyphenyl)ethanol) is a phenolic antioxidant that is naturally present in several foods such as wines and green tea and is present mostFormula:C8H10O2Purity:99.24% - 99.86%Color and Shape:SolidMolecular weight:138.16PI-1840
CAS:PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.Formula:C22H26N4O3Purity:98.82%Color and Shape:SolidMolecular weight:394.47SM-7368
CAS:The NF-κB Activation Inhibitor III, controls the biological activity of NF-κB. It is primarily used for Inflammation/Immunology applications.Formula:C10H5ClN4O5SPurity:99.64%Color and Shape:SolidMolecular weight:328.69Ref: TM-T22115
5mg44.00€10mg71.00€25mg128.00€50mg178.00€100mg268.00€200mg389.00€1mL*10mM (DMSO)52.00€IRAK-1-4 Inhibitor I
CAS:IRAK-1-4 Inhibitor I is a dual inhibitor of IRAK4 and IRAK1.
Formula:C20H21N5O4Purity:98% - 99.89%Color and Shape:SolidMolecular weight:395.41Tomatidine
CAS:Tomatidine serves as an anti-inflammatory agent by inhibiting NF-κB and JNK signaling pathways.
Formula:C27H45NO2Purity:99.94% - 99.98%Color and Shape:SolidMolecular weight:415.6511-Keto-β-boswellic acid
CAS:11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor, exerts dose dependent cardioprotective effect manifested.Formula:C30H46O4Purity:99.68%Color and Shape:SolidMolecular weight:470.68Ref: TM-TN1182
1mg57.00€5mg130.00€10mg200.00€25mg338.00€50mg497.00€100mg710.00€1mL*10mM (DMSO)133.00€Maslinic acid
CAS:Maslinic acid (Crategolic acid) is a DNA polymerase B inhibitor.Formula:C30H48O4Purity:98.1% - 99.98%Color and Shape:SolidMolecular weight:472.70Malachite green oxalate
CAS:Malachite green oxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions.Formula:C23H25N2·C2HO4C2H2O4Color and Shape:Dark Green Crystals With A Metallic LusterMolecular weight:463.51Sarsasapogenin
CAS:Sarsasapogenin (Parigenin) is a steroidal sapogenin, that is the aglycosidic portion of a plant saponin.Formula:C27H44O3Purity:90% - 99.73%Color and Shape:White Or Off-Withe PowderMolecular weight:416.64
