CCR
C-C chemokine receptors (CCRs) are a group of GPCRs that respond to chemokines, which are signaling molecules that guide the migration of immune cells to sites of inflammation or infection. CCRs play crucial roles in immune responses, inflammation, and the development of various diseases, including autoimmune disorders and cancer. Modulation of CCR activity is being explored as a therapeutic strategy for conditions such as rheumatoid arthritis, multiple sclerosis, and HIV infection. At CymitQuimica, we provide a range of high-quality CCR modulators to support your research in immunology, inflammation, and therapeutic development.
Found 140 products of "CCR"
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PNU-177864 hydrochloride
CAS:PNU-177864 hydrochloride is a potent, selective and orally active antagonist of dopamine D3 receptor.
Formula:C18H22ClF3N2O3SPurity:99.95%Color and Shape:SolidMolecular weight:438.89PNU-177864
CAS:PNU-177864 is a selective dopamine D3 receptor antagonist.Formula:C18H21F3N2O3SPurity:99.92%Color and Shape:SolidMolecular weight:402.43C-021 dihydrochloride
CAS:C-021 dihydrochloride is a potent CCR4 antagonist. It potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM.Formula:C27H43Cl2N5O2Purity:98.67%Color and Shape:SolidMolecular weight:540.57CCX354
CAS:CCX354 (CCR1 antagonist 1) is a potent small molecule CCR1 antagonist with anti-inflammatory activity for the treatment of rheumatoid arthritis.Formula:C22H22ClN7O2Purity:99.43% - 99.44%Color and Shape:SolidMolecular weight:451.91APC-3316 tosylate
CAS:APC-3316 tosylate is a vinyl sulfone cysteine protease inhibitor and selective CCR4 antagonist.Formula:C39H46N4O7S2Color and Shape:SolidMolecular weight:746.94GW 766994
CAS:GW 766994 is a specific and oral chemokine receptor-3 (CCR3) antagonist. It has the potential for asthma and eosinophilic bronchitis treatment.Formula:C21H24Cl2N4O3Purity:98.77%Color and Shape:SolidMolecular weight:451.35AF-399/42018025
CAS:AF-399/42018025 is a small-molecule CCR4 antagonist applied to investigate chemokine-mediated immune cell trafficking and inflammatory disease mechanisms.Formula:C26H16ClN3O4S3Purity:99.96%Color and Shape:SolidMolecular weight:566.07BMS-457
CAS:BMS-457 is a potent, CCR1-selective antagonist.Formula:C24H35ClN2O4Purity:98%Color and Shape:SolidMolecular weight:451JNJ-27141491
CAS:JNJ-27141491 is a potent, noncompetitive antagonist of human CCR2.Formula:C17H15F2N3O3SPurity:98%Color and Shape:SolidMolecular weight:379.38Cosalane
CAS:Cosalane (NSC 658586) is an HIV replication inhibitor and an inhibitor of chemokine receptor 7 (CCR7) signalling in humans and mice.Formula:C45H60Cl2O6Purity:99.53% - 99.78%Color and Shape:SolidMolecular weight:767.86Ancriviroc
CAS:Ancriviroc (SCH-351125) is an orally bioavailable small molecule chemokine receptor CCR5 antagonist.Cost-effective and quality-assured.Formula:C28H37BrN4O3Purity:99.76% - 99.82%Color and Shape:SolidMolecular weight:557.533CCR2 antagonist 5
CAS:JNJ-41443532: oral hCCR2 antagonist, IC50=37 nM, anti-chemotaxis, treats inflammation & diabetes.Formula:C22H25F3N4O3SPurity:99.98%Color and Shape:SolidMolecular weight:482.52BMS-817399
CAS:BMS-817399: oral CCR1 antagonist with binding and chemotaxis inhibition IC50s, potential for rheumatoid arthritis research.Formula:C23H36ClN3O4Purity:99.7%Color and Shape:SolidMolecular weight:454Ref: TM-T26861
1mg152.00€5mg319.00€10mg485.00€25mg770.00€50mg1,035.00€100mg1,395.00€1mL*10mM (DMSO)356.00€SB 328437
CAS:SB 328437 ((S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate) is an effective and selective antagonist of CCR3 (IC50 = 4.5 nM).Formula:C21H18N2O5Purity:99.54%Color and Shape:SolidMolecular weight:378.38Ref: TM-T23321
1mg39.00€5mg82.00€10mg123.00€25mg250.00€50mg394.00€100mg618.00€200mg874.00€1mL*10mM (DMSO)69.00€BMS CCR2 22
CAS:BMS CCR2 22 is a potent and selective antagonist of CCR2 with calcium flux IC50 of 18 nM, chemotaxis IC50 of 1 nM, and binding IC50 of 5.1 nM.Formula:C28H34F3N5O4SPurity:99.65%Color and Shape:SolidMolecular weight:593.66Ref: TM-T14688
1mg55.00€5mg110.00€10mg173.00€25mg349.00€50mg532.00€100mg718.00€200mg964.00€1mL*10mM (DMSO)147.00€GSK2239633A
CAS:GSK2239633A is an allosteric antagonist of CC-chemokine receptor 4 (CCR4) with a pIC50 of 7.96 for the binding of [125I]-TARC to human CCR4.Formula:C24H25ClN4O5S2Purity:99.82%Color and Shape:SolidMolecular weight:549.06Ref: TM-T11481
1mg35.00€5mg79.00€10mg118.00€25mg245.00€50mg355.00€100mg515.00€500mgTo inquire1mL*10mM (DMSO)87.00€CCR1 antagonist 6
CAS:CCR1 antagonist 6 is a CCR1 antagonist (IC50: 3 nM).
Formula:C21H23ClN4O3SPurity:99.02% - 99.15%Color and Shape:SolidMolecular weight:446.95Tanimilast
CAS:Tanimilast (CHF-6001) is a potent PDE4 inhibitor with IC50 of 0.026 nM, used topically for obstructive lung disease.Formula:C30H30Cl2F2N2O8SPurity:99.18%Color and Shape:SolidMolecular weight:687.54CCR4 antagonist 4
CAS:CCR4 Antagonist 4 (Compound 22) is a potent and selective antagonist of the CC chemokine receptor-4 (CCR4), displaying an IC50 value of 0.02 μM. It also inhibits MDC-mediated chemotaxis and Ca2+ mobilization, with IC50 values of 0.007 μM and 0.003 μM, respectively. This compound is utilized in research on allergic inflammation [1].Formula:C24H27Cl2N7OColor and Shape:SolidMolecular weight:500.42MLN-3897
CAS:MLN-3897 is an oral CCR1 antagonist, Ki 2.3 nM, blocks 125I-MIP-1α binding, and inhibits Akt signaling in MM cells.Formula:C30H31ClN2O4Purity:98.62%Color and Shape:SolidMolecular weight:519.03
