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TLR

TLR

Toll-like receptors (TLRs) are a class of proteins that play a critical role in the innate immune system by recognizing pathogen-associated molecular patterns (PAMPs) and initiating immune responses. TLRs are involved in detecting a wide range of pathogens, including bacteria, viruses, and fungi, and are essential for the activation of inflammatory signaling pathways. Dysregulation of TLR signaling is associated with chronic inflammatory diseases, autoimmune disorders, and cancer. At CymitQuimica, we offer a variety of high-quality TLR modulators to support your research in innate immunity, inflammation, and infectious disease.

Found 66 products of "TLR"

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  • TH1020
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    TH1020

    CAS:
    <p>TH1020 is a novel Inhibitor of Toll-Like Receptor 5 (TLR5)/Flagellin Complex with promising activity (IC50 =0.85±0.12 μm) and specificity.</p>
    Formula:C23H15N7S2
    Purity:99.23%
    Color and Shape:Solid
    Molecular weight:453.54

    Ref: TM-T8727

  • Motolimod
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    Motolimod

    CAS:
    <p>Motolimod (VTX-378) (VTX-2337) is an effective and specific Toll-like receptor (TLR) 8 agonist (EC50: 100 nM), &gt; 50-fold selectivity over TLR7.</p>
    Formula:C28H34N4O2
    Purity:97.43% - 99.66%
    Color and Shape:Solid
    Molecular weight:458.6

    Ref: TM-T6898

  • TLR7/8 agonist 1 dihydrochloride
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    TLR7/8 agonist 1 dihydrochloride

    CAS:
    <p>TLR7/8 agonist 1 dihydrochloride (TLR7/8 agonist-5d) is a TLR7/8 agonist which shows prominent immunostimulatory activities.</p>
    Formula:C22H27Cl2N5
    Purity:98.33%
    Color and Shape:Solid
    Molecular weight:432.39

    Ref: TM-T5561

  • Robinin
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    Robinin

    CAS:
    <p>Robinin: a kaempferol-derived flavone glycoside with antibacterial, diuretic traits; minimal effect on Colo 320 MDR1/LRP resistance; detected in MCF-7 cells.</p>
    Formula:C33H40O19
    Purity:98.78% - 99.13%
    Color and Shape:Solid
    Molecular weight:740.66

    Ref: TM-T2S0265

  • CymitQuimica logo
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    Paridiprubart

    CAS:
    <p>Paridiprubart (NI-0101) is a humanised monoclonal antibody targeting TLR4, ameliorative effects in COVID-19 patients with ARDS and rheumatoid arthritis.</p>
    Purity:95% - 95%
    Color and Shape:Liquid

    Ref: TM-T74427

  • CL264
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    CL264

    CAS:
    <p>CL264, a selective agonist of TLR7, can be used in studies about innate immune signals.</p>
    Formula:C19H23N7O4
    Purity:98.01%
    Color and Shape:Solid
    Molecular weight:413.43

    Ref: TM-T10833

  • AXC-715 trihydrochloride
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    AXC-715 trihydrochloride

    CAS:
    <p>AXC-715 trihydrochloride is a TLR7/8 agonist used to make PD-L1 adjuvanted antibody immunocouplings.</p>
    Formula:C18H28Cl3N5
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:420.81

    Ref: TM-T72253

  • TLR7 agonist 1
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    TLR7 agonist 1

    CAS:
    <p>TLR7 agonist 1 is a selective and oral TLR7 agonist (IC50: 90 nM).</p>
    Formula:C21H25N5O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:363.46

    Ref: TM-T13168

  • AZD8848
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    AZD8848

    CAS:
    <p>AZD8848 is a selective antedrug agonist of toll-like receptor 7 (TLR7). It is developed for the research of asthma and allergic rhinitis.</p>
    Formula:C29H43N7O5
    Color and Shape:Solid
    Molecular weight:569.7

    Ref: TM-T10437

  • TL8-506
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    TL8-506

    CAS:
    <p>TL8-506 is a selective and potent TLR8 agonist that induces cytokine and chemokine production.TL8-506 alleviates inflammatory and autoimmune diseases.</p>
    Formula:C20H17N3O2
    Purity:95% - 99.97%
    Color and Shape:Solid
    Molecular weight:331.37

    Ref: TM-T60977

  • DSR-6434
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    DSR-6434

    CAS:
    <p>DSR-6434 is a selective agonist of TLR7 with antitumor effect. DSR-6434 exhibits EC50s of 7.2 nM and 4.6 nM for human and mouse.</p>
    Formula:C19H28N8O2
    Purity:99.78%
    Color and Shape:Solid
    Molecular weight:400.48

    Ref: TM-T11108

  • AT791
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    AT791

    CAS:
    <p>AT791 is an orally available TLR7 and TLR9 inhibitor, suppressing TLR7 and TLR9 signaling, used in autoimmune lupus research.</p>
    Formula:C23H31N3O3
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:397.51

    Ref: TM-T61882

  • Rabeximod
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    Rabeximod

    CAS:
    <p>Rabeximod, an immunomodulator, eases autoimmune diseases, inhibits arthritis, and aids brain recovery post-injury by blocking inflammation.</p>
    Formula:C22H24ClN5O
    Purity:99.99%
    Color and Shape:Solid
    Molecular weight:409.91

    Ref: TM-T34249

  • BBIQ
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    BBIQ

    CAS:
    <p>BBIQ is a powerful vaccine adjuvant that enhances innate immune responses and a potent and selectively toll-like receptor 7 (TLR7) agonist with an EC50 of  59.1</p>
    Formula:C21H22N4
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:330.43

    Ref: TM-T14513

  • M62812
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    M62812

    CAS:
    <p>TLR4 inhibitor blocks LPS-induced NF-κB (IC50=2.4μg/mL), cytokines in PBMCs/HUVECs, and extends life in septic shock mice.</p>
    Formula:C13H13Cl2N3OS
    Purity:99.07%
    Color and Shape:Solid
    Molecular weight:330.23

    Ref: TM-T37292

  • SM360320
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    SM360320

    CAS:
    <p>SM360320 (CL-087) is a selective TLR7 agonist that blocks HCV replication in hepatocytes and aids immunology research.</p>
    Formula:C15H17N5O3
    Purity:99.13%
    Color and Shape:Solid
    Molecular weight:315.33

    Ref: TM-T19675

  • TLR7/8-IN-1
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    TLR7/8-IN-1

    CAS:
    <p>TLR7/8-IN-1, a crystalline TLR7/TLR8 inhibitor, is a valuable compound for autoimmune disease research.Cost-effective and quality-assured.</p>
    Formula:C29H40N8O2
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:532.68

    Ref: TM-T38078

  • TLR7 agonist 23
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    TLR7 agonist 23

    CAS:
    <p>TLR7 agonist23 (compound 12b) is a potent agonist of Toll-like receptor-7 (TLR7), with an EC50 value of 0.15 uM. It is suitable for research in immune diseases.</p>
    Formula:C21H22N4O2
    Color and Shape:Solid
    Molecular weight:362.42

    Ref: TM-T88779

  • TLR9-IN-1
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    TLR9-IN-1

    CAS:
    <p>TLR9-IN-1: selective, potent human TLR9 inhibitor (IC50: 7 nM), useful for researching immune-related diseases.</p>
    Formula:C23H31N7O
    Color and Shape:Solid
    Molecular weight:421.54

    Ref: TM-T62254

  • ABR-238901
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    ABR-238901

    CAS:
    <p>ABR-238901 is an oral, active S100A8/A9 blocker that inhibits the interaction of S100A8/A9 with its receptors RAGE(receptor for advanced glycation end products</p>
    Formula:C11H9BrClN3O4S
    Purity:98.63% - 98.71%
    Color and Shape:Solid
    Molecular weight:394.63

    Ref: TM-T39115