CymitQuimica logo
TLR

TLR

Toll-like receptors (TLRs) are a class of proteins that play a critical role in the innate immune system by recognizing pathogen-associated molecular patterns (PAMPs) and initiating immune responses. TLRs are involved in detecting a wide range of pathogens, including bacteria, viruses, and fungi, and are essential for the activation of inflammatory signaling pathways. Dysregulation of TLR signaling is associated with chronic inflammatory diseases, autoimmune disorders, and cancer. At CymitQuimica, we offer a variety of high-quality TLR modulators to support your research in innate immunity, inflammation, and infectious disease.

Found 66 products of "TLR"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • DSR-6434
    Targetmol
    + Info

    DSR-6434

    CAS:
    <p>DSR-6434 is a selective agonist of TLR7 with antitumor effect. DSR-6434 exhibits EC50s of 7.2 nM and 4.6 nM for human and mouse.</p>
    Formula:C19H28N8O2
    Purity:99.78%
    Color and Shape:Solid
    Molecular weight:400.48

    Ref: TM-T11108

  • AT791
    Targetmol
    + Info

    AT791

    CAS:
    <p>AT791 is an orally available TLR7 and TLR9 inhibitor, suppressing TLR7 and TLR9 signaling, used in autoimmune lupus research.</p>
    Formula:C23H31N3O3
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:397.51

    Ref: TM-T61882

  • Rabeximod
    Targetmol
    + Info

    Rabeximod

    CAS:
    <p>Rabeximod, an immunomodulator, eases autoimmune diseases, inhibits arthritis, and aids brain recovery post-injury by blocking inflammation.</p>
    Formula:C22H24ClN5O
    Purity:99.99%
    Color and Shape:Solid
    Molecular weight:409.91

    Ref: TM-T34249

  • BBIQ
    Targetmol
    + Info

    BBIQ

    CAS:
    <p>BBIQ is a powerful vaccine adjuvant that enhances innate immune responses and a potent and selectively toll-like receptor 7 (TLR7) agonist with an EC50 of  59.1</p>
    Formula:C21H22N4
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:330.43

    Ref: TM-T14513

  • M62812
    Targetmol
    + Info

    M62812

    CAS:
    <p>TLR4 inhibitor blocks LPS-induced NF-κB (IC50=2.4μg/mL), cytokines in PBMCs/HUVECs, and extends life in septic shock mice.</p>
    Formula:C13H13Cl2N3OS
    Purity:99.07%
    Color and Shape:Solid
    Molecular weight:330.23

    Ref: TM-T37292

  • SM360320
    Targetmol
    + Info

    SM360320

    CAS:
    <p>SM360320 (CL-087) is a selective TLR7 agonist that blocks HCV replication in hepatocytes and aids immunology research.</p>
    Formula:C15H17N5O3
    Purity:99.13%
    Color and Shape:Solid
    Molecular weight:315.33

    Ref: TM-T19675

  • TLR7/8-IN-1
    Targetmol
    + Info

    TLR7/8-IN-1

    CAS:
    <p>TLR7/8-IN-1, a crystalline TLR7/TLR8 inhibitor, is a valuable compound for autoimmune disease research.Cost-effective and quality-assured.</p>
    Formula:C29H40N8O2
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:532.68

    Ref: TM-T38078

  • TLR7 agonist 23
    Targetmol
    + Info

    TLR7 agonist 23

    CAS:
    <p>TLR7 agonist23 (compound 12b) is a potent agonist of Toll-like receptor-7 (TLR7), with an EC50 value of 0.15 uM. It is suitable for research in immune diseases.</p>
    Formula:C21H22N4O2
    Color and Shape:Solid
    Molecular weight:362.42

    Ref: TM-T88779

  • TLR9-IN-1
    Targetmol
    + Info

    TLR9-IN-1

    CAS:
    <p>TLR9-IN-1: selective, potent human TLR9 inhibitor (IC50: 7 nM), useful for researching immune-related diseases.</p>
    Formula:C23H31N7O
    Color and Shape:Solid
    Molecular weight:421.54

    Ref: TM-T62254

  • ABR-238901
    Targetmol
    + Info

    ABR-238901

    CAS:
    <p>ABR-238901 is an oral, active S100A8/A9 blocker that inhibits the interaction of S100A8/A9 with its receptors RAGE(receptor for advanced glycation end products</p>
    Formula:C11H9BrClN3O4S
    Purity:98.63% - 98.71%
    Color and Shape:Solid
    Molecular weight:394.63

    Ref: TM-T39115

  • CU-CPD107
    Targetmol
    + Info

    CU-CPD107

    CAS:
    <p>CU-CPD107 selectively activates TLR8 and ssRNA, inhibits TLR8 with R848 (IC50=13.7 μM), and coactivates with ssRNA.</p>
    Formula:C16H21IN2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:400.25

    Ref: TM-T35349

  • TLR7 agonist 28
    Targetmol
    + Info

    TLR7 agonist 28

    CAS:
    <p>TLR7 agonist28 (compound 3) is a potent TLR7 agonist. This compound can be combined with anti-tumor monoclonal antibodies (mAb) for use in cancer immunotherapy.</p>
    Formula:C26H25N9O7
    Color and Shape:Solid
    Molecular weight:575.533

    Ref: TM-T204940

  • Creatine ethyl ester
    Targetmol
    + Info

    Creatine ethyl ester

    CAS:
    <p>Creatine ethyl ester (CEE) is a readily available form of creatine commonly used in supplements. It can upregulate TLRs (TLR2, 3, 4, and TLR7) over a short period.</p>
    Formula:C6H13N3O2
    Color and Shape:Solid
    Molecular weight:159.186

    Ref: TM-T206807

  • SARM1-IN-4
    Targetmol
    + Info

    SARM1-IN-4

    CAS:
    <p>SARM1-IN-4 (Compound 7) is an orally active SARM1 inhibitor that reduces plasma neurofilament light chain (NfL) levels in a mouse model following a 50 mg/kg oral dose. By inhibiting the NAD+ hydrolase activity of SARM1, it prevents programmed axon degeneration, making it useful for research in neurodegenerative and neurological diseases such as multiple sclerosis, amyotrophic lateral sclerosis, Parkinson's disease, and peripheral neuropathy.</p>
    Formula:C13H17F2N3O2
    Color and Shape:Solid
    Molecular weight:285.29

    Ref: TM-T206825

  • LHC-165
    Targetmol
    + Info

    LHC-165

    CAS:
    <p>LHC-165 is an agonist of TLR7. It also has the potential to treat solid tumors.</p>
    Formula:C29H32F2N3O7P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:603.55

    Ref: TM-T15751

  • TLR7/8/9 antagonist 2
    Targetmol
    + Info

    TLR7/8/9 antagonist 2

    CAS:
    <p>TLR7/8/9 antagonist 2 is an orally active and highly bioavailable vTLR7/8/9 antagonist. It inhibits HEK/hTLR7, HEK/hTLR8, and HEK/hTLR9 with IC50s of 0.011 μM, 0.029 μM, and 0.052 μM, respectively. TLR7/8/9 antagonist 2 can be used to study auto-inflammatory diseases such as systemic lupus erythematosus or lupus nephritis.</p>
    Formula:C23H31N7
    Purity:98%
    Color and Shape:Soild
    Molecular weight:405.54

    Ref: TM-T72035

    ne
    Discontinued
    Discontinued product