IL Receptor
Interleukin receptors (IL receptors) are a group of receptors that bind to interleukins, a family of cytokines that play essential roles in immune system regulation, inflammation, and hematopoiesis. Dysregulation of interleukin signaling is associated with various inflammatory and autoimmune diseases, making IL receptors critical targets for therapeutic intervention. IL receptor antagonists are being explored for the treatment of conditions such as rheumatoid arthritis, psoriasis, and inflammatory bowel disease. At CymitQuimica, we offer a range of high-quality IL receptor modulators to support your research in cytokine signaling, immunology, and inflammatory disease therapy.
Found 111 products of "IL Receptor"
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Anti-Mouse IL-4 Antibody (11B11)
Anti-Mouse IL-4 Antibody (11B11) is an inhibitory antibody targeting mouse IL-4, with the clone number 11B11.Purity:99%Color and Shape:Odour LiquidMolecular weight:150 kDaIL-17A antagonist 1
CAS:IL-17A antagonist 1 is an IL-17A antagonist for the study of interleukin-related inflammatory and immune diseases.Formula:C33H41FN6O4Purity:99.46%Color and Shape:SolidMolecular weight:604.71Anakinra
CAS:Anakinra (Raleukin) is an antagonist of recombinant, nonglycosylated human IL-1R. It is the first biological agent to block the pro-inflammatory effects.Formula:C759H1186N208O232S10Purity:95% - ≥95%Color and Shape:SolidMolecular weight:17257.6GIBH-130
CAS:GIBH-130 markedly inhibits the IL-1β secretion by activated microglia (IC50: 3.4 nM). GIBH-130 is an effective inhibitor of neuroinflammation.Formula:C20H20N6OPurity:99.52%Color and Shape:SolidMolecular weight:360.41Clodronate disodium tetrahydrate
CAS:Clodronate disodium tetrahydrate (Clastoban) inhibits bone resorption and soft tissue calcification.Formula:CH10Cl2Na2O10P2Purity:98%Color and Shape:SolidMolecular weight:360.92Secukinumab
CAS:Secukinumab is a fully humanized monoclonal anti-IL-17A antibody and the first in its class to be approved by the US Food and Drug Administration for thePurity:97.4% (SDS-PAGE); 98.3% (SEC-HPLC) - 99.10%Color and Shape:LiquidMolecular weight:147.93 kDaApilimod
CAS:Apilimod (STA 5326) inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis.Formula:C23H26N6O2Purity:99.38% - 99.89%Color and Shape:SolidMolecular weight:418.49YM-90709
CAS:YM-90709 is a new-type antagonist inhibiting the binding of interleukin-5 to the interleukin-5 receptor.Formula:C22H21N3O2Purity:>99.99%Color and Shape:SolidMolecular weight:359.42Apilimod mesylate
CAS:Apilimod mesylate (STA 5326 mesylate) is a potent IL-12/IL-23 inhibitor.Formula:C25H34N6O8S2Purity:99.51% - ≥95%Color and Shape:SolidMolecular weight:610.7VGX-1027
CAS:VGX-1027 (GIT 27) is an isoxazole compound with various immunomodulatory properties.Formula:C11H11NO3Purity:99.54% - 99.86%Color and Shape:SolidMolecular weight:205.21Apilimod 2HCl
CAS:Apilimod 2HCl (STA 5326 2HCl) is a PIKFYVE kinase inhibitor used in the study of amyotrophic lateral sclerosis.Formula:C23H28Cl2N6O2Purity:98.41%Color and Shape:SolidMolecular weight:491.41AF 12198 Acetate
AF 12198 Acetate is a novel low molecular weight antagonist of IL-1Formula:C98H127N19O24Purity:95.27%Color and Shape:SolidMolecular weight:1955.17Lyn peptide inhibitor acetate
Potent, cell-permeable Lyn inhibitor; hinders IL-5 receptor signaling, vital for asthma/allergy research.Formula:C117H188N30O26Purity:98%Color and Shape:SolidMolecular weight:2430.98Esonarimod
CAS:Esonarimod (KE-298) is an antirheumatic drug.Formula:C14H16O4SPurity:97.44%Color and Shape:SolidMolecular weight:280.34Suplatast (Tosilate)
CAS:Suplatast Tosilate (IPD 1151T) is a novel capsular anti-asthmatic drug. It ( IC50 above 100 μM) inhibits both IgE production, IL-4 and IL-5 synthesis.Formula:C23H33NO7S2Purity:99.34% - 99.65%Color and Shape:White Or Off-White CrystalsMolecular weight:499.64IL-17A inhibitor 1
CAS:IL-17A inhibitor 1 is a IL-17A inhibitor with IC50 of <9.45 nM in alphalisa assay. IL-17A inhibitor 1 inhibits HT-29 cells with IC50 of 9.3 nM.
Formula:C24H27F5N8O4Purity:99.37% - 99.37%Color and Shape:SolidMolecular weight:586.51CP 424174
CAS:CP 424174 blocks IL-1β processing (IC50: 210 nM), halts mature IL-1β formation, limits NLRP3, and is effective orally in vivo.Formula:C22H29ClN2O4SPurity:>99.99%Color and Shape:SolidMolecular weight:452.99GSK717
CAS:GSK717: potent, selective NOD2 inhibitor; disrupts NOD2/TLR2 synergy; no effect on NOD1, TNFR1, TLR2.
Formula:C28H28N4O2Purity:97.34% - 99.01%Color and Shape:SolidMolecular weight:452.55Sirukumab
CAS:Sirukumab (CNTO-136) is a humanized monoclonal antibody binding to IL-6, inhibiting IL-6-mediated signaling and transcription activator activation.Purity:>95%Color and Shape:LiquidMolecular weight:144.58 kDaBrazikumab
CAS:Brazikumab (AMG 139) is a humanized antibody targeting IL-23 by binding to the P19 subunit, a selective IL-23p19 antagonist.Purity:98% (SDS-PAGE); 97.7% (SEC-HPLC) - 98% (SDS-PAGE); 97.7% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.78 kDaSatralizumab
CAS:Satralizumab (SA-237) is a humanized antibody targeting interleukin-6 (IL-6), used in research on neuromyelitis optica spectrum disorder (NMOSD).Purity:95%Color and Shape:LiquidMolecular weight:143.42 kDaInolimomab
CAS:Inolimomab is a monoclonal antibody targeting CD25 (IL-2R α chain) for studying acute graft-versus-host disease (aGVHD).Purity:95% - >95.0% (SDS-PAGE); 99.49% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.34 kDaPicankibart
CAS:Picankibart (IBI112) is a human recombinant monoclonal antibody targeting IL-23p19, indicated for psoriasis treatment.Purity:95% - 97.0% (SDS-PAGE); 99.4% (SEC-HPLC)Color and Shape:LiquidMolecular weight:144.75 kDaManfidokimab
CAS:Manfidokimab is an anti-IL-4Rα mAb that blocks IL-4/IL-13 signaling, in trials for atopic dermatitis.Purity:95%Color and Shape:LiquidMolecular weight:~150 kDaBimekizumab
CAS:Bimekizumab is a humanised monoclonal antibody targeting IL17A/IL17F, blocking inflammation-driven osteoblast differentiation.Purity:>99.99%Color and Shape:LiquidMolecular weight:147.24 kDaEbdarokimab
CAS:Ebdarokimab (anti-IL-12/23 p40 mAb) inhibits the IL-12/IL-23 pathway and is under clinical investigation for SLE and plaque psoriasis.Purity:95%Color and Shape:LiquidMolecular weight:145.66 kDaAnrukinzumab
CAS:Anrukinzumab (IMA-638) is an anti-IL-13 mAb with anti-inflammatory effects, in development for ulcerative colitis and asthma.Purity:95%Color and Shape:LiquidMolecular weight:145.38 kDaZiralimumab
CAS:Ziralimumab（ABX-RB2） is a monoclonal antibody that targets and inhibits IL-2 receptor, thereby modulating the immune response.Purity:95%Color and Shape:LiquidAnti-Mouse IL-1a Antibody (ALF-161)
Anti-Mouse IL-1a Antibody (ALF-161) is a monoclonal antibody inhibitor targeting mouse IL-1α. inhibit CD8+ T cell responses and reverse myeloid cell expansion.Purity:95%Color and Shape:Odour LiquidCasdozokitug
CAS:Casdozokitug is a human IgG1κ anti-IL-27 antibody that blocks immunosuppressive activity, relevant in tumor immunology and immune checkpoint therapy research.Purity:95% - 95.1% (SDS-PAGE); 97.2% (SEC-HPLC)Color and Shape:LiquidMolecular weight:147.35 kDaGumokimab
CAS:Gumokimab (AK 111) is an anti-IL-17A mAb that blocks pro-inflammatory signaling, a candidate for psoriasis and ankylosing spondylitis.Purity:95%Color and Shape:LiquidMolecular weight:146.50 kDaBempikibart
CAS:Bempikibart (ADX-914) is a fully humanised monoclonal antibody targeting IL-7Rα, inhibiting IL-17 and TSLP (Thymic stromal lymphopoietin), inflammation.Purity:95% - 98.9% (SDS-PAGE); 97.4% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.75 kDaAnti-Mouse IL-6R Antibody (15A7)
Anti-Mouse IL-6R Antibody (15A7) is an antibody inhibitor targeting mouse IL-6R, derived from rats, widely used in research and experimentsPurity:99% - 99%Color and Shape:Odour LiquidLebrikizumab
CAS:Lebrikizumab is a humanised monoclonal antibody that targets and inhibits interleukin 13 (IL-13), suppressing Th2 inflammation.asthma and atopic dermatitis.Purity:95%Color and Shape:LiquidMolecular weight:145.27 kDaTirnovetmab
CAS:Tirnovetmab (KIND-016) is a fully dog-derived monoclonal antibody targeting IL-31 with high affinity, suitable for investigating canine atopic dermatitis.Purity:95% - 96.6% (SDS-PAGE); 99.4% (SEC-HPLC)Color and Shape:LiquidMolecular weight:148.83 kDaGevokizumab
CAS:Gevokizumab (S-78989) is a humanised monoclonal antibody targeting IL-1β, allosteric regulation, diabetes, cancer, inflammation, and cardiovascular diseases.Purity:95%Color and Shape:LiquidMolecular weight:144.93 kDaAfasevikumab
CAS:Afasevikumab (RG 7624) is a fully humanised monoclonal antibody that targets and neutralises IL-17A and IL-17F,autoimmune diseases and inflammation.Purity:95%Color and Shape:LiquidMolecular weight:146.07 kDaSapelizumab
Sapelizumab is a humanised antibody targeting IL-6Ra/CD126, huIgG2-type heavy chains and huκ-type light chains, IL-6 antagonist NMOSD.Molecular weight:~150 kDaLusvertikimab
CAS:Lusvertikimab (OSE-127) is a humanized anti-IL7R antibody with anti-leukemic efficacy and can be used to study leukemia.Purity:95% - 98.4% (SDS-PAGE); 99% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.63 kDaD228
CAS:D228 is an oral anti-inflammatory,inhibi B and T lymphocytes, down-regulation of MyD88/TRAF6/p38 and up-regulation of IL-10,inflammatory bowel disease (IBD).Formula:C22H28O12Purity:99.91%Color and Shape:SolidMolecular weight:484.45Etokimab
CAS:Etokimab (ANB-020) is a humanised monoclonal antibody targeting IL-33, neutrophil migration, atopic dermatitis, asthma, and sinusitis.Purity:95%Color and Shape:LiquidMolecular weight:146.54 kDaVopikitug
CAS:Vopikitug is a humanized monoclonal antibody targeting IL-2RA with antitumor activity. It can be used to study cancer.Purity:99.1% (SDS-PAGE); 96.5% (SEC-HPLC) - 99.1% (SDS-PAGE); 96.5% (SEC-HPLC)Color and Shape:LiquidMolecular weight:144.53 kDaBI605906
CAS:BI605906 is an IKKβ inhibitor that can be used to study inflammatory skin diseases such as psoriasis.
Formula:C17H22F2N4O3S2Purity:97.14%Color and Shape:SolidMolecular weight:432.51A-802715
CAS:A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases theFormula:C16H26N4O3Purity:96.29%Color and Shape:SolidMolecular weight:322.4LMT-28
CAS:LMT-28 is an inhibitor of IL-6 and selectively inhibits IL-6-induced phosphorylation of gp130, STAT3, and JAK2.Formula:C17H29NO4Purity:97.55%Color and Shape:SolidMolecular weight:311.42Dersalazine
CAS:Dersalazine, a PAF inhibitor, reduces IL-17 to treat colitis in rodents, potentially aiding ulcerative colitis patients.
Formula:C35H32N6O4Purity:99.62%Color and Shape:SolidMolecular weight:600.67NFAT Transcription Factor Regulator-1
CAS:NFAT Transcription Factor Regulator-1 is an synthesis inhibitor of IL-2 (IC50 of 182 nM).Formula:C17H10F6N4O2Purity:99.90%Color and Shape:SolidMolecular weight:416.28Ref: TM-T12218
1mg44.00€1mL*10mM (DMSO)87.00€5mg88.00€10mg135.00€25mg243.00€50mg358.00€100mg512.00€500mg1,018.00€IL-4-inhibitor-1
CAS:IL-4 inhibitor: Binds IL-4 (Kd=1.8 μM), blocks activity (EC50=1.81 μM), selective vs. IL-13, stops IL-4-JAK1-STAT6 in THP-1 monocytes (EC50=3.1 μM).Formula:C18H12FN3O2Purity:99.53% - 99.89%Color and Shape:SolidMolecular weight:321.31Ref: TM-T36527
1mg44.00€1mL*10mM (DMSO)130.00€5mg172.00€10mg313.00€25mg530.00€50mg757.00€100mg1,044.00€Resiniferatoxin
CAS:Resiniferatoxin ((+)-Resiniferatoxin) is a highly potent synthetic TRPV1 agonist.Cost-effective and quality-assured.Formula:C37H40O9Purity:93.08% - 99.34%Color and Shape:SolidMolecular weight:628.71BIRT-377
CAS:BIRT-377: orally active, hinders ICAM-1/LFA-1, blocks IL-2, useful for immune research. (Ki=25.8 nM).Formula:C18H15BrCl2N2O2Purity:99.93%Color and Shape:SolidMolecular weight:442.13
