cAMP
cAMP is a second messenger important in many biological processes, including the regulation of metabolism, gene expression, and cell growth. In the MAPK signaling pathway, cAMP can modulate the activity of various kinases, including PKA, which in turn influences the MAPK cascade. Dysregulation of cAMP signaling is implicated in various diseases, including cancer and cardiovascular disorders. At CymitQuimica, we offer a variety of cAMP modulators to support your research in signal transduction, metabolism, and disease pathology.
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JNJ-39758979
CAS:1046447-90-8
JNJ-39758979: selective H4 receptor antagonist, Kis 12.5/5.3/25 nM (human/mouse/monkey), blocks histamine cAMP inhibition (pA2 7.9).
Formula:
C11H19N5
Purity:
98.00% - 98.3%
Color and Shape:
Solid
Molecular weight:
221.3
Ref: TM-T11723L
| 1mg | 74.00 € | ||
| 5mg | 159.00 € | ||
| 10mg | 247.00 € | ||
| 25mg | 419.00 € | ||
| 50mg | 608.00 € | ||
| 100mg | 894.00 € | ||
| 1mL*10mM (DMSO) | 168.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
ESI-05
CAS:5184-64-5
ESI-05 (NSC-116966) is a specific 0.4 μM IC50 EPAC2 antagonist that blocks cAMP-induced EPAC2 and …
Formula:
C16H18O2S
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
274.38
Ref: TM-T15247
| 2mg | 39.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 91.00 € | ||
| 25mg | 163.00 € | ||
| 50mg | 265.00 € | ||
| 100mg | 454.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
A-3 hydrochloride
CAS:78957-85-4
A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 …
Formula:
C12H14Cl2N2O2S
Purity:
99.32%
Color and Shape:
Solid
Molecular weight:
321.22
Ref: TM-T14069
| 1mg | 35.00 € | ||
| 5mg | 68.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 278.00 € | ||
| 100mg | 445.00 € | ||
| 500mg | 920.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Bithionol
CAS:97-18-7
Bithionol (Actamer), formerly marketed as an active ingredient in various topical drug products, was shown …
Formula:
C12H6Cl4O2S
Purity:
99.27%
Color and Shape:
White Or Grayish-White Crystalline Powder Phenolic Odor (Ntp 1992)
Molecular weight:
356.05
Ref: TM-T0830
| 500mg | 54.00 € | ||
| 1mL*10mM (DMSO) | 60.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
MR-L2
CAS:2374703-19-0
MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4).
Formula:
C19H16Cl3FN4O
Purity:
98.09% - 98.94%
Color and Shape:
Solid
Molecular weight:
441.71
Ref: TM-T12103
| 1mg | 143.00 € | ||
| 2mg | 203.00 € | ||
| 5mg | 346.00 € | ||
| 10mg | 519.00 € | ||
| 25mg | 835.00 € | ||
| 50mg | 1,140.00 € | ||
| 100mg | 1,532.00 € | ||
| 500mg | 3,067.00 € | ||
| 1mL*10mM (DMSO) | 375.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
HJC0197
CAS:1383539-73-8
HJC0197 is a selective Epac antagonist; blocks cAMP-induced activation with IC50=5.9 μM for Epac2.
Formula:
C19H21N3OS
Purity:
98.05%
Color and Shape:
Solid
Molecular weight:
339.45
Ref: TM-T15485
| 2mg | 37.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 130.00 € | ||
| 50mg | 182.00 € | ||
| 100mg | 272.00 € | ||
| 200mg | 411.00 € | ||
| 1mL*10mM (DMSO) | 62.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Bucladesine sodium
CAS:16980-89-5
Bucladesine sodium (DC2797) is a cAMP analog with cell-permeable properties.
Formula:
C18H23N5NaO8P
Purity:
96.56% - 99.58%
Color and Shape:
White Powder
Molecular weight:
491.37
Ref: TM-T1418
| 2g | 390.00 € | ||
| 25mg | 36.00 € | ||
| 50mg | 49.00 € | ||
| 100mg | 86.00 € | ||
| 200mg | 114.00 € | ||
| 500mg | 181.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
CE3F4
CAS:143703-25-7
CE3F4 is a selective antagonist of exchange protein directly activated by cAMP (Epac1; IC50s of …
Formula:
C11H10Br2FNO
Purity:
97% - 97.15%
Color and Shape:
Solid
Molecular weight:
351.01
Ref: TM-T12616L
| 5mg | 56.00 € | ||
| 10mg | 91.00 € | ||
| 25mg | 151.00 € | ||
| 50mg | 273.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Mirabegron
CAS:223673-61-8
Mirabegron (YM178) is a beta-3 adrenergic agonist that is used for treatment of overactive bladder …
Formula:
C21H24N4O2S
Purity:
99.14%
Color and Shape:
Light Yellow To Yellow Solid
Molecular weight:
396.51
Ref: TM-T1671
| 1mg | 35.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 113.00 € | ||
| 25mg | 189.00 € | ||
| 50mg | 343.00 € | ||
| 100mg | 493.00 € | ||
| 500mg | 1,095.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
MRS-1706
CAS:264622-53-9
MRS-1706: Ki of 1.39nM for A2B; selective inverse agonist; also affects A2A, A1, A3.
Formula:
C27H29N5O5
Purity:
97.95%
Color and Shape:
Solid
Molecular weight:
503.55
Ref: TM-T16136
| 1mg | 36.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 238.00 € | ||
| 50mg | 467.00 € | ||
| 100mg | 678.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Licoarylcoumarin
CAS:125709-31-1
Licoarylcoumarin inhibits cAMP phosphodiesterase, fights VRE bacteria, has anti-HIV properties, and blocks xanthine oxidase.
Formula:
C21H20O6
Purity:
98%
Color and Shape:
Solid
Molecular weight:
368.38
Ref: TM-TN4433
| 5mg | 850.00 € | ||
| 1mL*10mM (DMSO) | 869.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
BC 11-38
CAS:686770-80-9
BC 11-38 is a potent, selective PDE biodepressant which is mainly effective against PDE11 (IC50 …
Formula:
C15H16N2OS2
Purity:
97.71% - 98.72%
Color and Shape:
Solid
Molecular weight:
304.43
Ref: TM-T21865
| 2mg | 46.00 € | ||
| 5mg | 71.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 202.00 € | ||
| 50mg | 330.00 € | ||
| 100mg | 527.00 € | ||
| 200mg | 747.00 € | ||
| 500mg | 1,099.00 € | ||
| 1mL*10mM (DMSO) | 91.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
2-PCCA hydrochloride
CAS:1609563-70-3
2-PCCA hydrochloride, a racemate, is a potent and selective GPR88 receptor agonist showing inhibition of …
Formula:
C30H39Cl2N3O
Purity:
99.65% - 99.96%
Color and Shape:
Soild
Molecular weight:
528.56
Ref: TM-T80666
| 1mg | 183.00 € | ||
| 5mg | 452.00 € | ||
| 10mg | 647.00 € | ||
| 25mg | 1,003.00 € | ||
| 50mg | 1,392.00 € | ||
| 100mg | 1,828.00 € | ||
| 500mg | 3,671.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Panaxydol
CAS:72800-72-7
Panaxydol has anti-cancer activity, can inhibit the growth and apoptosis of cancer cells, the signaling …
Formula:
C17H24O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
260.37
Ref: TM-TN2039
| 1mg | 208.00 € | ||
| 5mg | 991.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
OX04528
CAS:3028055-45-7
OX04528 is an orally active and potent GPR84 biased agonist.OX04528 inhibits cAMP signaling and may …
Formula:
C16H13F6NO2
Purity:
99.74%
Color and Shape:
Soild
Molecular weight:
365.27
Ref: TM-T84313
| 1mg | 198.00 € | ||
| 5mg | 490.00 € | ||
| 10mg | 687.00 € | ||
| 25mg | 1,072.00 € | ||
| 50mg | 1,479.00 € | ||
| 100mg | 1,894.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Catalpalactone
CAS:1585-68-8
Catalpalactone: antitermitic, cytotoxic, inhibits NO in cells (IC50 9.80µM), reduces dopamine synthesis, hinders TPA-induced EBV-EA …
Formula:
C15H14O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
258.27
Ref: TM-TN3607
| 5mg | 1,378.00 € | ||
| 1mL*10mM (DMSO) | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Fargesone B
CAS:116424-70-5
Fargesone B inhibits the vascular smooth muscle contraction by suppressing the voltage- and receptor-activated calcium …
Formula:
C21H24O6
Purity:
98%
Color and Shape:
Solid
Molecular weight:
372.417
Ref: TM-TN4051
| 5mg | 557.00 € | ||
| 1mL*10mM (DMSO) | 576.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Dodoviscin A
CAS:1372527-25-7
Dodoviscin A: a potential agent for altering pigmentation, inhibits melanin synthesis; also promotes fat cell …
Formula:
C27H32O9
Purity:
98%
Color and Shape:
Solid
Molecular weight:
500.544
Ref: TM-TN3882
| 5mg | 774.00 € | ||
| 1mL*10mM (DMSO) | 1,171.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
TDI-10229
CAS:2810887-45-5
TDI-10229: potent oral sAC inhibitor, IC50=195 nM. Good mouse pharmacokinetics for in vivo use.
Formula:
C16H16ClN5
Purity:
97.77%
Color and Shape:
Soild
Molecular weight:
313.78
Ref: TM-T64355
| 1mg | 41.00 € | ||
| 5mg | 159.00 € | ||
| 10mg | 233.00 € | ||
| 25mg | 416.00 € | ||
| 50mg | 625.00 € | ||
| 100mg | 903.00 € | ||
| 200mg | 1,246.00 € | ||
| 1mL*10mM (DMSO) | 171.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Kushenol A
CAS:99217-63-7
Kushenol A is a kind of Adenosine 3', 5'-cyclic monophosphate(cAMP)phosphodiesterase inhibitiors, it shows selective alpha-glucosidase …
Formula:
C25H28O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
408.49
Ref: TM-TN1841
| 5mg | 741.00 € | ||
| 1mL*10mM (DMSO) | 1,021.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
