MNK
MNKs are a group of kinases that interact with MAPKs, particularly ERK and p38, to regulate protein synthesis by phosphorylating the eukaryotic initiation factor 4E (eIF4E). MNK signaling plays a role in cellular stress responses, inflammation, and cancer progression. Targeting MNKs is an emerging strategy in cancer therapy and anti-inflammatory treatments. At CymitQuimica, we provide a selection of MNK inhibitors and modulators to support your research in protein synthesis regulation, oncology, and inflammation.
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ETC-206
CAS:1464151-33-4
ETC-206 is a selective inhibitor of MNK1 and MNK2 (IC50s: 64 nM and 86 nM).
Formula:
C25H20N4O2
Purity:
99.72% - 99.79%
Color and Shape:
Solid
Molecular weight:
408.45
Ref: TM-T15250
| 2mg | 35.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 145.00 € | ||
| 50mg | 221.00 € | ||
| 100mg | 328.00 € | ||
| 500mg | 713.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
QL-X-138 HCl
QL-X-138 HCl is a BTK/MNK dual kinase inhibitor with anticancer activity and anti-dengue virus 2 …
Formula:
C25H20ClN5O2
Purity:
98.89%
Color and Shape:
Soild
Molecular weight:
457.91
Ref: TM-T38960L
| 1mg | 181.00 € | ||
| 5mg | 447.00 € | ||
| 10mg | 640.00 € | ||
| 25mg | 998.00 € | ||
| 50mg | 1,377.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
SLV-2436
CAS:2095704-43-9
SLV-2436 (SEL201-88) is a novel effective and ATP-competitive inhibitor of MNK1 and MNK2 (IC50: 10.8/5.4 …
Formula:
C19H15ClN4O
Purity:
99.85%
Color and Shape:
Solid
Molecular weight:
350.8
Ref: TM-T4424
| 1mg | 81.00 € | ||
| 2mg | 104.00 € | ||
| 5mg | 167.00 € | ||
| 10mg | 271.00 € | ||
| 25mg | 517.00 € | ||
| 50mg | 744.00 € | ||
| 100mg | 1,023.00 € | ||
| 1mL*10mM (DMSO) | 186.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
HG-10-102-01
CAS:1351758-81-0
HG-10-102-01 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2, IC50 of 20.3 nM).
Formula:
C17H20ClN5O3
Purity:
99.59%
Color and Shape:
Solid
Molecular weight:
377.83
Ref: TM-T7196
| 2mg | 37.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 91.00 € | ||
| 25mg | 164.00 € | ||
| 50mg | 255.00 € | ||
| 100mg | 367.00 € | ||
| 200mg | 521.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
CGP 57380
CAS:522629-08-9
CGP 57380 (MNK1 Inhibitor) is a potent MNK1 inhibitor with IC50 of 2.2 μM, exhibiting …
Formula:
C11H9FN6
Purity:
99.89%
Color and Shape:
Solid
Molecular weight:
244.23
Ref: TM-T6440
| 1mg | 46.00 € | ||
| 2mg | 60.00 € | ||
| 5mg | 89.00 € | ||
| 10mg | 140.00 € | ||
| 25mg | 256.00 € | ||
| 50mg | 426.00 € | ||
| 100mg | 612.00 € | ||
| 200mg | 857.00 € | ||
| 1mL*10mM (DMSO) | 113.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Tomivosertib
CAS:1849590-01-7
Tomivosertib (eFT508) is a potent, highly selective MNK1 and MNK2 inhibitor with IC50 value of …
Formula:
C17H20N6O2
Purity:
97.34% - 99.67%
Color and Shape:
Solid
Molecular weight:
340.38
Ref: TM-T3468
| 1mg | 64.00 € | ||
| 5mg | 166.00 € | ||
| 10mg | 238.00 € | ||
| 25mg | 446.00 € | ||
| 50mg | 644.00 € | ||
| 100mg | 916.00 € | ||
| 1mL*10mM (DMSO) | 179.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
MNK1/2-IN-5
CAS:1426928-20-2
MNK1/2-IN-5 is a potent and selective MNK1/2 inhibitor with anticancer activity and can be used …
Formula:
C17H16N4O2
Color and Shape:
Liquid
Molecular weight:
308.33
Ref: TM-T60733
| 1mg | 61.00 € | ||
| 5mg | 132.00 € | ||
| 10mg | 203.00 € | ||
| 25mg | 342.00 € | ||
| 50mg | 504.00 € | ||
| 100mg | 718.00 € | ||
| 500mg | 1,450.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
DS12881479
CAS:2373065-59-7
DS12881479 can be used in cancer research which is a potent and selective inhibitor of …
Formula:
C16H19N3OS
Purity:
100%
Color and Shape:
Liquid
Molecular weight:
301.41
Ref: TM-T60681
| 1mg | 96.00 € | ||
| 5mg | 236.00 € | ||
| 10mg | 354.00 € | ||
| 25mg | 637.00 € | ||
| 50mg | 857.00 € | ||
| 100mg | 1,126.00 € | ||
| 200mg | 1,537.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
EB1
CAS:42951-68-8
EB1 is an MNK kinase inhibitor that inhibits cancer cell growth, promotes apoptosis, and inhibits …
Formula:
C18H14N4
Purity:
99.82%
Color and Shape:
Liquid
Molecular weight:
286.33
Ref: TM-T73582
| 1g | 3,239.00 € | ||
| 1mg | 74.00 € | ||
| 5mg | 157.00 € | ||
| 10mg | 221.00 € | ||
| 25mg | 367.00 € | ||
| 50mg | 551.00 € | ||
| 100mg | 785.00 € | ||
| 500mg | 2,181.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
