Ras
Ras proteins are small GTPases that act as molecular switches in the MAPK signaling pathway, controlling cell growth, differentiation, and survival. Activated Ras initiates a signaling cascade that includes Raf, MEK, and ERK, leading to various cellular responses. Mutations in Ras genes are common in cancers, making Ras an important focus of cancer research. At CymitQuimica, we offer a range of Ras modulators to support your research in cancer biology, signal transduction, and therapeutic development.
Found 155 products of "Ras"
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BI1701963
BI1701963 is an orally effective inhibitor that targets the SOS1 and KRAS interaction, specifically inhibiting the activation of KRAS by blocking its GTP loading. This compound is utilized in cancer research to explore potential therapeutic effects against KRAS-driven malignancies.Formula:C47H62N8O4SColor and Shape:SolidMolecular weight:835.11Rapaprutug
CAS:Rapaprutug is a monoclonal antibody that targets human KARS1 (lysyl-tRNA synthetase 1). It can block inflammation-related signaling pathways involving KARS1, thereby reducing the production and release of inflammatory factors. Rapaprutug shows potential for research into inflammatory diseases.Color and Shape:LiquidKRAS inhibitor-33
KRAS inhibitor-33 (compound 115a) is a pyrido[2,3-d]pyrimidine derivative that serves as an effective inhibitor of KRAS, exhibiting an IC50 value of ≤ 100nM.Formula:C33H39ClF2N6O3Color and Shape:SolidMolecular weight:641.15KRAS inhibitor-42
KRAS inhibitor-42 (compound 8) is an effective USP7 inhibitor that exhibits high affinity for GDP-bound KRASG12D, with a Ki value of 2.7 μM.Formula:C34H47ClN8O4S2Color and Shape:SolidMolecular weight:730.28502Goralatide
CAS:Goralatide, isolated from fetal calf bone marrow, exerts a high inhibitory activity on the proliferation of hematopoietic pluripotent stem cells.Formula:C20H33N5O9Purity:98%Color and Shape:SolidMolecular weight:487.5SOS1-IN-11
CAS:SOS1-IN-11 is an effective inhibitor of SOS1 (IC50 = 30 nM).Formula:C22H24F3N5OPurity:99.4%Color and Shape:SolidMolecular weight:431.45Ref: TM-T60029
1mg75.00€5mg169.00€1mL*10mM (DMSO)180.00€10mg284.00€25mg452.00€50mg645.00€100mg867.00€pan-KRAS-IN-10
Pan-KRAS-IN-10 (Compound 58) acts as an inhibitor of the human tumor mutant gene KRAS. It suppresses the proliferation of KRAS mutant cells, specifically AsPC-1 (G12D mutant) and SW480 (G12V mutant), with IC50 values of 0.7 and 0.24 nM, respectively.Formula:C45H57N7O5SMolecular weight:807.41419ADT-007
CAS:ADT-007 is a pan-RAS inhibitor with potent anticancer activity.Formula:C26H24FNO5Purity:97.75%Color and Shape:SoildMolecular weight:449.47Ref: TM-T85316
1mg47.00€5mg96.00€1mL*10mM (DMSO)104.00€10mg124.00€25mg200.00€50mg353.00€100mg602.00€200mg982.00€MAPK Inhibitor Library
A unique collection of 365 compounds targeting MAPK signaling for drug discovery in MAPK related diseases;Color and Shape:Odour SolidRef: TM-L1400
1mgTo inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquireMC 976
CAS:MC 976 is a derivative of Vitamin D3.Formula:C27H42O3Purity:98%Color and Shape:SolidMolecular weight:414.63GGTI298 Trifluoroacetate
CAS:GGTI298 trifluoroacetate (GGTI298TFA salt) is a geranylgeranyltransferase I inhibitor that causes cell cycle arrest and induces apoptosis.Formula:C27H33N3O3S·C2HF3O2Purity:98.07% - >99.99%Color and Shape:SolidMolecular weight:593.66Ras Inhibitory Peptide acetate
Ras Inhibitory Peptide acetate, involved in cancer-related Ras signaling.Formula:C55H95N19O13Purity:96.63%Color and Shape:SolidMolecular weight:1230.46G12 TFA
G12 (Ras5-17) TFA is a wild-type Ras peptide comprising amino acids 5-17 (KLVVVGAGGVGKS). It serves as a control in studies involving mutant Ras peptides, such as V12.Formula:C54H96F3N15O17Molecular weight:1283.70607KRAS G12D inhibitor 20
KRAS G12D inhibitor 20 (Compound 14) is a selective G12D KRAS inhibitor with antitumor activity.Formula:C18H26N6OMolecular weight:342.21681KRAS inhibitor-38
CAS:KRAS Inhibitor-38 (Example 18) is a potent inhibitor capable of effectively suppressing the activity of KRAS G12C, KRAS G12D, and KRAS G12V in vivo.Formula:C53H68ClF2N9O8SColor and Shape:SolidMolecular weight:1064.68Pan-RAS-IN-7
CAS:Pan-RAS-IN-7 (Compound D101) is a broad-spectrum RAS inhibitor used in the synthesis of antibody-drug conjugates (ADCs). It is also applicable in cancer research.Formula:C59H76N8O8Color and Shape:SolidMolecular weight:1025.28Sevelamer Carbonate
CAS:Sevelamer carbonate, a non-absorbed polymer, binds phosphate with carbonate instead of chloride.Formula:(C3H7N·C3H5ClO)x·xCH2O3Purity:98%Color and Shape:SolidMolecular weight:211.64Rasarfin
CAS:Rasarfin inhibits Ras and ARF6.Formula:C23H24ClN3O3Purity:97.98%Color and Shape:SolidMolecular weight:425.91Ref: TM-T9407
1mg38.00€5mg75.00€1mL*10mM (DMSO)84.00€10mg110.00€25mg193.00€50mg323.00€100mg460.00€200mg620.00€K-Ras(G12C) inhibitor 12
CAS:K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).Formula:C15H17ClIN3O3Purity:97.16%Color and Shape:SolidMolecular weight:449.67(S)-AMG-510
CAS:(S)-AMG-510 is the S-type compound of AMG-510 (Sotorasib), which effectively and selectively inhibits KRASG12C.Cost-effective and quality-assured.Formula:C30H30F2N6O3Purity:99.05% - 99.76%Color and Shape:SolidMolecular weight:560.594Ref: TM-T22258
2mg34.00€5mg50.00€1mL*10mM (DMSO)73.00€10mg80.00€25mg147.00€50mg259.00€100mg404.00€500mg888.00€
