ERK
ERK is a key protein in the MAPK (Mitogen-Activated Protein Kinase) signaling pathway, which is involved in transmitting signals from cell surface receptors to the DNA in the cell nucleus. ERK plays a crucial role in the regulation of various cellular processes, including proliferation, differentiation, and survival. Dysregulation of ERK signaling is associated with the development of cancer and other diseases, making it an important target for therapeutic intervention. At CymitQuimica, we offer a selection of high-quality ERK inhibitors and modulators to support your research in cell signaling, oncology, and therapeutic development.
Found 217 products of "ERK"
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N-tert-butyl-α-Phenylnitrone
CAS:N-tert-butyl-α-Phenylnitrone ((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) inhibits COX2 catalytic activity.Formula:C11H15NOPurity:99.46% - 99.84%Color and Shape:SolidMolecular weight:177.24Pluripotin
CAS:Pluripotin (SC1) (SC1), which keep embryonic stem cell (ESC) self-renewal, is a dual inhibitor of extracellular signal-regulated kinase 1 (ERK1, MAPK3) andFormula:C27H25F3N8O2Purity:98.77% - 98.82%Color and Shape:SolidMolecular weight:550.53Ref: TM-T6948
1mg34.00€2mg48.00€5mg63.00€1mL*10mM (DMSO)74.00€10mg88.00€25mg140.00€50mg207.00€100mg333.00€Tenuifoliside A
CAS:Tenuifoliside A has anti-apoptotic , neuroprotective activity.Formula:C31H38O17Purity:98.99% - 99.91%Color and Shape:SolidMolecular weight:682.62BAY885
CAS:BAY885 is a new ERK5 inhibitor.Formula:C25H28F3N7O2Purity:99.83%Color and Shape:SolidMolecular weight:515.53Mogrol
CAS:Mogrol, a biometabolite of mogrosides, functions by inhibiting the ERK1/2 and STAT3 pathways, diminishing CREB activation, and activating AMPK signaling.Formula:C30H52O4Purity:99.85% - 99.90%Color and Shape:SolidMolecular weight:476.73Temuterkib
CAS:LY3214996 (Temuterkib) is a potent oral ERK1/2 inhibitor with potential cancer-fighting properties.
Formula:C22H27N7O2SPurity:99.57% - >99.99%Color and Shape:SolidMolecular weight:453.56GPR34 receptor antagonist 2
CAS:GPR34 receptor antagonist 2 (Tyrosine, N-[(2E)-3-(4'-chloro[1,1'-biphenyl]-4-yl)-1-oxo-2-propen-1-yl]-O-(phenylmethyl)-) is an anti-inflammatory agent.Formula:C31H26ClNO4Purity:97.26%Color and Shape:SolidMolecular weight:512Ref: TM-T8848
1mg110.00€5mg259.00€1mL*10mM (DMSO)288.00€10mg425.00€25mg700.00€50mg982.00€100mg1,314.00€500mg2,637.00€Ulixertinib
CAS:Ulixertinib (VRT752271) (BVD-523, VRT752271) is an effective and reversible ERK1/ERK2 inhibitor. The IC50 of Ulixertinib is less than 0.3 nM for ERK2.Formula:C21H22Cl2N4O2Purity:99.31% - 99.95%Color and Shape:SolidMolecular weight:433.33Peramivir Trihydrate
CAS:Peramivir Trihydrate (RWJ-270201) is a neuraminidase inhibitor (IC50: 0.09 nM) which prevents normal processing of virus particles such that virus particles are
Formula:C15H28N4O4·3H2OPurity:99.52% - ≥95%Color and Shape:SolidMolecular weight:382.45Ref: TM-T2522
2mg47.00€5mg70.00€10mg103.00€25mg188.00€50mg311.00€100mg439.00€200mg635.00€500mg938.00€ERK5-IN-1
CAS:ERK5-IN-1 is a potent ERK5 inhibitor (IC50: 87 nM). It also inhibits LRRK2[G2019S] (IC50: 26 nM).Formula:C25H29N7O2Purity:97.70%Color and Shape:SolidMolecular weight:459.54Triptonide
CAS:Triptonide treats autoimmune diseases, has antileukemic/tumor effects, is anti-inflammatory, and boosts IL-37.Formula:C20H22O6Purity:99.11% - 99.64%Color and Shape:White Crystalline PowderMolecular weight:358.39Ref: TM-T5S1058
1mg52.00€2mg74.00€5mg108.00€1mL*10mM (DMSO)133.00€10mg158.00€25mg268.00€50mg409.00€100mg595.00€200mg833.00€SHP389
CAS:SHP389 is a highly effective allosteric inhibitor of SHP2, inhibiting SHP2 and p-ERK, used in cancer research.Formula:C23H29ClN8O2Purity:98.24%Color and Shape:SolidMolecular weight:484.98ERK-IN-4
CAS:ERK-IN-4 is a cell-permeable ERK inhibitor with potential antiproliferative effects for the study of diseases caused by immune dysfunction.Formula:C14H17ClN2O3SPurity:98.92% - 99.84%Color and Shape:SolidMolecular weight:328.814Ref: TM-T36675
1mg46.00€2mg57.00€5mg93.00€1mL*10mM (DMSO)99.00€10mg137.00€25mg219.00€50mg324.00€100mg484.00€Ulixertinib hydrochloride
CAS:Ulixertinib hydrochloride (Ulixertinib HCl) is an ERK1/2 inhibitor with anticancer and antitumor activity that inhibits the NB cell cycle and promotes apoptosisFormula:C21H23Cl3N4O2Purity:99.85%Color and Shape:SolidMolecular weight:469.79PB1
CAS:PB1, a stable borane-protected TCEP analogue, effectively reduces disulfides intracellularly and aids retinal cell survival post-axotomy.Formula:C14H22BO4PColor and Shape:SolidMolecular weight:296.11ADTL-EI1712
CAS:ADTL-EI1712: ERK1/2/5 inhibitor (ERK1 IC50=40.43nM, ERK5=64.5nM), blocks HL-60/MKN74 cell growth, not HeLa; effective in MKN74 mouse model.Formula:C22H18Cl2N4O2S2Color and Shape:SolidMolecular weight:505.442,5-Dihydroxybiphenyl
CAS:2,5-Dihydroxybiphenyl: a small molecule that induces trichothiodystrophy A protein dimerization, modulating TFIIH activity.
Formula:C12H10O2Purity:99.66%Color and Shape:White To Grey-Brownish PowderMolecular weight:186.21D-87503
CAS:D-87503 is a dual extracellular signaling-related kinase (ERK)/PI3K inhibitor.Formula:C17H15N5OSColor and Shape:SolidMolecular weight:337.4ERK5-IN-4
CAS:ERK5-IN-4 (34b) is a potent, specific ERK5 inhibitor; IC50: 77 nM full-length, 300 nM ΔTAD in HEK293 cells.Formula:C16H11Cl2FN4O2Color and Shape:SolidMolecular weight:381.19CAY10561
CAS:CAY10561: potent, selective ERK2 inhibitor (Ki=2nM); blocks cell proliferation; IC50 in COLO 205 cells: 0.54μM.Formula:C22H17Cl2FN4O2Color and Shape:SolidMolecular weight:459.3
