CymitQuimica logo
CFTR

CFTR

CFTR is a chloride channel protein that regulates the transport of chloride and bicarbonate ions across epithelial cell membranes, playing a crucial role in maintaining fluid balance in tissues. Mutations in the CFTR gene lead to cystic fibrosis, a genetic disorder characterized by the production of thick mucus that can clog airways and lead to severe respiratory and digestive problems. At CymitQuimica, we provide a selection of CFTR modulators to support your research in cystic fibrosis, ion transport, and genetic disorders.

Found 64 products of "CFTR"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • AF-2785
    Targetmol
    + Info

    AF-2785

    CAS:
    <p>In epididymal epithelial cells, AF-2785 inhibits cystic fibrosis transmembrane conductance regulator Cl(-) channels.</p>
    Formula:C17H12Cl2N2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:347.2

    Ref: TM-T23648

  • SRI-37240
    Targetmol
    + Info

    SRI-37240

    CAS:
    <p>SRI-37240 suppresses CFTR nonsense mutations, aids in fixing premature termination codons, works with G418.</p>
    Formula:C24H23N3O2
    Purity:98.73%
    Color and Shape:Solid
    Molecular weight:385.46

    Ref: TM-T61702

  • VRT-532
    Targetmol
    + Info

    VRT-532

    CAS:
    <p>VRT-532 (CFpot-532) is an effective modulator of CFTR and is commonly used in studies of cystic fibrosis (CF) caused by CFTR defects.</p>
    Formula:C16H14N2O
    Purity:99.88% - 99.93%
    Color and Shape:Solid
    Molecular weight:250.3

    Ref: TM-T29114

  • Bamocaftor
    Targetmol
    + Info

    Bamocaftor

    CAS:
    <p>Bamocaftor corrects CFTR in CF, restoring F508del-CFTR function, used with tezacaftor and VX-561 for F508del/MF patients.</p>
    Formula:C28H32F3N5O4S
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:591.65

    Ref: TM-T30293

  • Crinecerfont
    Targetmol
    + Info

    Crinecerfont

    CAS:
    <p>Crinecerfont (SSR-125543) is a CRF1 antagonist, useful in congenital adrenal hyperplasia research.</p>
    Formula:C27H28ClFN2OS
    Purity:98.01% - 98.55%
    Color and Shape:Solid
    Molecular weight:483.04

    Ref: TM-T31095

  • UCCF-853
    Targetmol
    + Info

    UCCF-853

    CAS:
    <p>UCCF-853 是一种小分子 CFTR 调节剂，可用于研究囊性纤维化。</p>
    Formula:C14H8ClF3N2O
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:312.67

    Ref: TM-T29041

  • PG01
    Targetmol
    + Info

    PG01

    CAS:
    <p>PG01 is a potent CFTR Cl-channel potentiator, effective against ΔF508 (Ka 0.3 μM), and also against E193K, G970R and G551D (CFTR mutants), with Kd values of 0.</p>
    Formula:C28H29N3O2
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:439.55

    Ref: TM-T16516

  • CFTR corrector 8
    Targetmol
    + Info

    CFTR corrector 8

    CAS:
    <p>CFTR corrector 8: potent for cystic fibrosis research, modulates CFTR protein.</p>
    Formula:C29H27F2NO7
    Purity:99.57%
    Color and Shape:Solid
    Molecular weight:539.52

    Ref: TM-T63806

  • CFTR corrector 12
    Targetmol
    + Info

    CFTR corrector 12

    CAS:
    <p>CFTR corrector 12 is a CFTR corrector that rescues all mutant proteins except M760R ABCA3 and can be used to study cystic fibrosis.</p>
    Formula:C19H21ClN4O2S2
    Purity:99.47%
    Color and Shape:Solid
    Molecular weight:436.98

    Ref: TM-T79578

  • CP 154526
    Targetmol
    + Info

    CP 154526

    CAS:
    <p>CRF1 receptor antagonist</p>
    Formula:C23H33ClN4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:400.99

    Ref: TM-T22682

  • DNDS
    Targetmol
    + Info

    DNDS

    CAS:
    <p>DNDS is a channel blocker of voltage-dependent cystic fibrosis transmembrane conductance regulator (CFTR).</p>
    Formula:C14H8N2Na2O10S2
    Purity:99.92%
    Color and Shape:Physical Description White Powder (Ntp 1992)
    Molecular weight:474.33

    Ref: TM-T20341

  • (R)-Vanzacaftor
    Targetmol
    + Info

    (R)-Vanzacaftor

    CAS:
    <p>(R)-Vanzacaftor ((R)-VX-121) is a cystic fibrosis transmembrane conductance regulator (CFTR) modulator [1].</p>
    Formula:C32H39N7O4S
    Color and Shape:Solid
    Molecular weight:617.76

    Ref: TM-T84699

  • Chromanol 293B
    Targetmol
    + Info

    Chromanol 293B

    CAS:
    <p>slow delayed rectifier K+ current (IKs) blocker</p>
    Formula:C15H20N2O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:324.4

    Ref: TM-T22662

  • BPO-27 racemate
    Targetmol
    + Info

    BPO-27 racemate

    CAS:
    <p>BPO-27 racemate (BPO-27 (racemate)) is an effective CFTR inhibitor with IC50 of 8 nM.</p>
    Formula:C26H18BrN3O6
    Purity:97.67% - 98.86%
    Color and Shape:Solid
    Molecular weight:548.34

    Ref: TM-T10591

  • CRF1 receptor antagonist-1
    Targetmol
    + Info

    CRF1 receptor antagonist-1

    CAS:
    <p>CRF1 Receptor Antagonist-1 (Compound 2), a CRF1 receptor antagonist, is utilized in research pertaining to congenital adrenal hyperplasia (CAH) [1].</p>
    Formula:C27H28ClFN2O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:499.04

    Ref: TM-T79793

  • (R)-Elexacaftor
    Targetmol
    + Info

    (R)-Elexacaftor

    CAS:
    <p>(R)-Elexacaftor (compound 37) is the enantiomer of Elexacaftor (compound 1). (R)-Elexacaftor is a CFTR modulator with an EC50 of 0.29 μM for CFTR dF508.</p>
    Formula:C26H34F3N7O4S
    Purity:98.991%
    Color and Shape:Solid
    Molecular weight:597.65

    Ref: TM-T78240

  • CFTR corrector 6
    Targetmol
    + Info

    CFTR corrector 6

    CAS:
    <p>CFTR corrector 6, a potent CFTR potentiator, aids cystic fibrosis research and related disorders.</p>
    Formula:C22H13F4N9
    Color and Shape:Solid
    Molecular weight:479.39

    Ref: TM-T37686

  • CFTR corrector 4
    Targetmol
    + Info

    CFTR corrector 4

    CAS:
    <p>Potent, oral CFTR corrector 4 targets cystic fibrosis, increasing cell surface CFTR levels.</p>
    Formula:C29H27F2NO7
    Purity:99.32%
    Color and Shape:Solid
    Molecular weight:539.52

    Ref: TM-T10776

  • CFTR corrector 15
    Targetmol
    + Info

    CFTR corrector 15

    CAS:
    <p>CFTR Corrector 15 (Compound 4172) serves as a corrector for cystic fibrosis transmembrane conductance regulator (CFTR). When used in combination with VX-809, it addresses the folding defects of F508del-CFTR. CFTR Corrector 15 is also applicable in the research of cystic fibrosis.</p>
    Formula:C24H22ClN5O2S
    Color and Shape:Solid
    Molecular weight:479.98

    Ref: TM-T89966

  • CFTR corrector 17
    Targetmol
    + Info

    CFTR corrector 17

    CAS:
    <p>CFTRcorrector 17 (example 17) is a regulator of the cystic fibrosis transmembrane conductance regulator (CFTR). It is utilized in the study of diseases mediated by CFTR.</p>
    Formula:C18H15FN2O2
    Color and Shape:Solid
    Molecular weight:310.32

    Ref: TM-T201013