
CFTR
CFTR is a chloride channel protein that regulates the transport of chloride and bicarbonate ions across epithelial cell membranes, playing a crucial role in maintaining fluid balance in tissues. Mutations in the CFTR gene lead to cystic fibrosis, a genetic disorder characterized by the production of thick mucus that can clog airways and lead to severe respiratory and digestive problems. At CymitQuimica, we provide a selection of CFTR modulators to support your research in cystic fibrosis, ion transport, and genetic disorders.
Found 64 products of "CFTR"
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CFTR corrector 16
CAS:<p>CFTRcorrector 16 (Compound 39) is a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR), utilized in the research of cystic fibrosis disease.</p>Formula:C27H26ClN5O2SColor and Shape:SolidMolecular weight:520.05ARN23765
CAS:<p>ARN23765 is an F508del-CFTR corrector with an EC50 of 38 pM in human bronchial epithelial cells. It enhances the maturation and function of F508del-CFTR at the cell membrane, influencing ion transport and secretion, thereby addressing the pathological mechanisms of cystic fibrosis (CF).</p>Formula:C30H22F5N3O6Color and Shape:SolidMolecular weight:615.504CFTR corrector 18
CAS:<p>CFTRcorrector 18 (Compound I-99) acts as a modulator of the cystic fibrosis transmembrane conductance regulator (CFTR). It enhances the processing and trafficking of CFTR, thereby increasing the amount of CFTR present on the cell surface. CFTRcorrector 18 holds potential for research in cystic fibrosis (CF).</p>Formula:C38H40N6O5SColor and Shape:SolidMolecular weight:692.826Crinecerfont tosylate
CAS:<p>Crinecerfont tosylate is an effective oral CRF1 receptor antagonist. It is applicable to studies involving congenital adrenal hyperplasia (CAH).</p>Formula:C34H36ClFN2O4S2Color and Shape:SolidMolecular weight:655.242
