CFTR
CFTR is a chloride channel protein that regulates the transport of chloride and bicarbonate ions across epithelial cell membranes, playing a crucial role in maintaining fluid balance in tissues. Mutations in the CFTR gene lead to cystic fibrosis, a genetic disorder characterized by the production of thick mucus that can clog airways and lead to severe respiratory and digestive problems. At CymitQuimica, we provide a selection of CFTR modulators to support your research in cystic fibrosis, ion transport, and genetic disorders.
Found 66 products of "CFTR"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
CFTR corrector 8
CAS:CFTR corrector 8: potent for cystic fibrosis research, modulates CFTR protein.
Formula:C29H27F2NO7Purity:99.57%Color and Shape:SolidMolecular weight:539.52Chromanol 293B
CAS:Chromanol 293B, Cardiac IK and CFTR chloride current inhibitor (IC50=1-19 μM), weak KATP channel blocker, for arrhythmia research.Formula:C15H20N2O4SPurity:98%Color and Shape:SolidMolecular weight:324.4(R)-Elexacaftor
CAS:(R)-Elexacaftor (compound 37) is the enantiomer of Elexacaftor (compound 1). (R)-Elexacaftor is a CFTR modulator with an EC50 of 0.29 μM for CFTR dF508.Formula:C26H34F3N7O4SPurity:98.991%Color and Shape:SolidMolecular weight:597.65Ref: TM-T78240
1mg99.00€5mg249.00€1mL*10mM (DMSO)329.00€10mg402.00€25mg782.00€50mg1,180.00€100mg1,848.00€200mg2,489.00€CRF1 receptor antagonist-1
CAS:CRF1 Receptor Antagonist-1 (Compound 2), a CRF1 receptor antagonist, is utilized in research pertaining to congenital adrenal hyperplasia (CAH) [1].Formula:C27H28ClFN2O2SPurity:98%Color and Shape:SolidMolecular weight:499.04CFTR corrector 6
CAS:CFTR corrector 6, a potent CFTR potentiator, aids cystic fibrosis research and related disorders.Formula:C22H13F4N9Color and Shape:SolidMolecular weight:479.39CFTR corrector 12
CAS:CFTR corrector 12 is a CFTR corrector that rescues all mutant proteins except M760R ABCA3 and can be used to study cystic fibrosis.Formula:C19H21ClN4O2S2Purity:99.47%Color and Shape:SolidMolecular weight:436.98DNDS
CAS:DNDS is a channel blocker of voltage-dependent cystic fibrosis transmembrane conductance regulator (CFTR).Formula:C14H8N2Na2O10S2Purity:99.92%Color and Shape:Physical Description White Powder (Ntp 1992)Molecular weight:474.33BPO-27 racemate
CAS:BPO-27 racemate (BPO-27 (racemate)) is an effective CFTR inhibitor with IC50 of 8 nM.Formula:C26H18BrN3O6Purity:97.67% - 98.86%Color and Shape:SolidMolecular weight:548.34Ref: TM-T10591
1mg44.00€5mg111.00€1mL*10mM (DMSO)128.00€10mg166.00€25mg265.00€50mg388.00€100mg535.00€200mg718.00€(R)-Vanzacaftor
CAS:(R)-Vanzacaftor ((R)-VX-121) is a cystic fibrosis transmembrane conductance regulator (CFTR) modulator [1].Formula:C32H39N7O4SColor and Shape:SolidMolecular weight:617.76CFTR corrector 4
CAS:Potent, oral CFTR corrector 4 targets cystic fibrosis, increasing cell surface CFTR levels.Formula:C29H27F2NO7Purity:99.32%Color and Shape:SolidMolecular weight:539.52Ref: TM-T10776
1mg71.00€5mg166.00€1mL*10mM (DMSO)192.00€10mg250.00€25mg507.00€50mg713.00€100mg1,018.00€500mg2,035.00€CFTR corrector 18
CAS:CFTRcorrector 18 (Compound I-99) acts as a modulator of the cystic fibrosis transmembrane conductance regulator (CFTR). It enhances the processing and trafficking of CFTR, thereby increasing the amount of CFTR present on the cell surface. CFTRcorrector 18 holds potential for research in cystic fibrosis (CF).Formula:C38H40N6O5SColor and Shape:SolidMolecular weight:692.826Crinecerfont tosylate
CAS:Crinecerfont tosylate is an effective oral CRF1 receptor antagonist. It is applicable to studies involving congenital adrenal hyperplasia (CAH).Formula:C34H36ClFN2O4S2Color and Shape:SolidMolecular weight:655.242CFTR corrector 15
CAS:CFTR Corrector 15 (Compound 4172) serves as a corrector for cystic fibrosis transmembrane conductance regulator (CFTR). When used in combination with VX-809, it addresses the folding defects of F508del-CFTR. CFTR Corrector 15 is also applicable in the research of cystic fibrosis.Formula:C24H22ClN5O2SColor and Shape:SolidMolecular weight:479.98CFTR corrector 16
CAS:CFTRcorrector 16 (Compound 39) is a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR), utilized in the research of cystic fibrosis disease.Formula:C27H26ClN5O2SColor and Shape:SolidMolecular weight:520.05CFTR corrector 17
CAS:CFTRcorrector 17 (example 17) is a regulator of the cystic fibrosis transmembrane conductance regulator (CFTR). It is utilized in the study of diseases mediated by CFTR.Formula:C18H15FN2O2Color and Shape:SolidMolecular weight:310.32ARN23765
CAS:ARN23765 is an F508del-CFTR corrector with an EC50 of 38 pM in human bronchial epithelial cells. It enhances the maturation and function of F508del-CFTR at the cell membrane, influencing ion transport and secretion, thereby addressing the pathological mechanisms of cystic fibrosis (CF).Formula:C30H22F5N3O6Color and Shape:SolidMolecular weight:615.504
