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CFTR

CFTR

CFTR is a chloride channel protein that regulates the transport of chloride and bicarbonate ions across epithelial cell membranes, playing a crucial role in maintaining fluid balance in tissues. Mutations in the CFTR gene lead to cystic fibrosis, a genetic disorder characterized by the production of thick mucus that can clog airways and lead to severe respiratory and digestive problems. At CymitQuimica, we provide a selection of CFTR modulators to support your research in cystic fibrosis, ion transport, and genetic disorders.

Found 64 products of "CFTR"

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  • DNDS
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    DNDS

    CAS:
    <p>DNDS is a channel blocker of voltage-dependent cystic fibrosis transmembrane conductance regulator (CFTR).</p>
    Formula:C14H8N2Na2O10S2
    Purity:99.92%
    Color and Shape:Physical Description White Powder (Ntp 1992)
    Molecular weight:474.33

    Ref: TM-T20341

  • (R)-Vanzacaftor
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    (R)-Vanzacaftor

    CAS:
    <p>(R)-Vanzacaftor ((R)-VX-121) is a cystic fibrosis transmembrane conductance regulator (CFTR) modulator [1].</p>
    Formula:C32H39N7O4S
    Color and Shape:Solid
    Molecular weight:617.76

    Ref: TM-T84699

  • Chromanol 293B
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    Chromanol 293B

    CAS:
    <p>slow delayed rectifier K+ current (IKs) blocker</p>
    Formula:C15H20N2O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:324.4

    Ref: TM-T22662

  • BPO-27 racemate
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    BPO-27 racemate

    CAS:
    <p>BPO-27 racemate (BPO-27 (racemate)) is an effective CFTR inhibitor with IC50 of 8 nM.</p>
    Formula:C26H18BrN3O6
    Purity:97.67% - 98.86%
    Color and Shape:Solid
    Molecular weight:548.34

    Ref: TM-T10591

  • CRF1 receptor antagonist-1
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    CRF1 receptor antagonist-1

    CAS:
    <p>CRF1 Receptor Antagonist-1 (Compound 2), a CRF1 receptor antagonist, is utilized in research pertaining to congenital adrenal hyperplasia (CAH) [1].</p>
    Formula:C27H28ClFN2O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:499.04

    Ref: TM-T79793

  • (R)-Elexacaftor
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    (R)-Elexacaftor

    CAS:
    <p>(R)-Elexacaftor (compound 37) is the enantiomer of Elexacaftor (compound 1). (R)-Elexacaftor is a CFTR modulator with an EC50 of 0.29 μM for CFTR dF508.</p>
    Formula:C26H34F3N7O4S
    Purity:98.991%
    Color and Shape:Solid
    Molecular weight:597.65

    Ref: TM-T78240

  • CFTR corrector 6
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    CFTR corrector 6

    CAS:
    <p>CFTR corrector 6, a potent CFTR potentiator, aids cystic fibrosis research and related disorders.</p>
    Formula:C22H13F4N9
    Color and Shape:Solid
    Molecular weight:479.39

    Ref: TM-T37686

  • CFTR corrector 4
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    CFTR corrector 4

    CAS:
    <p>Potent, oral CFTR corrector 4 targets cystic fibrosis, increasing cell surface CFTR levels.</p>
    Formula:C29H27F2NO7
    Purity:99.32%
    Color and Shape:Solid
    Molecular weight:539.52

    Ref: TM-T10776

  • CFTR corrector 15
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    CFTR corrector 15

    CAS:
    <p>CFTR Corrector 15 (Compound 4172) serves as a corrector for cystic fibrosis transmembrane conductance regulator (CFTR). When used in combination with VX-809, it addresses the folding defects of F508del-CFTR. CFTR Corrector 15 is also applicable in the research of cystic fibrosis.</p>
    Formula:C24H22ClN5O2S
    Color and Shape:Solid
    Molecular weight:479.98

    Ref: TM-T89966

  • CFTR corrector 17
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    CFTR corrector 17

    CAS:
    <p>CFTRcorrector 17 (example 17) is a regulator of the cystic fibrosis transmembrane conductance regulator (CFTR). It is utilized in the study of diseases mediated by CFTR.</p>
    Formula:C18H15FN2O2
    Color and Shape:Solid
    Molecular weight:310.32

    Ref: TM-T201013

  • CFTR corrector 16
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    CFTR corrector 16

    CAS:
    <p>CFTRcorrector 16 (Compound 39) is a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR), utilized in the research of cystic fibrosis disease.</p>
    Formula:C27H26ClN5O2S
    Color and Shape:Solid
    Molecular weight:520.05

    Ref: TM-T200113

  • ARN23765
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    ARN23765

    CAS:
    <p>ARN23765 is an F508del-CFTR corrector with an EC50 of 38 pM in human bronchial epithelial cells. It enhances the maturation and function of F508del-CFTR at the cell membrane, influencing ion transport and secretion, thereby addressing the pathological mechanisms of cystic fibrosis (CF).</p>
    Formula:C30H22F5N3O6
    Color and Shape:Solid
    Molecular weight:615.504

    Ref: TM-T205032

  • CFTR corrector 18
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    CFTR corrector 18

    CAS:
    <p>CFTRcorrector 18 (Compound I-99) acts as a modulator of the cystic fibrosis transmembrane conductance regulator (CFTR). It enhances the processing and trafficking of CFTR, thereby increasing the amount of CFTR present on the cell surface. CFTRcorrector 18 holds potential for research in cystic fibrosis (CF).</p>
    Formula:C38H40N6O5S
    Color and Shape:Solid
    Molecular weight:692.826

    Ref: TM-T206874

  • Crinecerfont tosylate
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    Crinecerfont tosylate

    CAS:
    <p>Crinecerfont tosylate is an effective oral CRF1 receptor antagonist. It is applicable to studies involving congenital adrenal hyperplasia (CAH).</p>
    Formula:C34H36ClFN2O4S2
    Color and Shape:Solid
    Molecular weight:655.242

    Ref: TM-T205414