Potassium Channel
Potassium channels are a diverse group of membrane proteins that facilitate the flow of potassium ions (K+) across the cell membrane. These channels play a crucial role in maintaining the resting membrane potential, regulating cell volume, and controlling the excitability of neurons and muscle cells. Potassium channels are involved in various physiological processes, including cardiac rhythm regulation, insulin secretion, and neurotransmitter release. Dysregulation of potassium channels is linked to conditions such as arrhythmias, epilepsy, and hypertension. At CymitQuimica, we offer a wide range of potassium channel modulators to support your research in electrophysiology, cardiovascular health, and neurobiology.
Found 304 products of "Potassium Channel"
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Ssm spooky toxin
Ssm Spooky Toxin, derived from Scolopendra mutilans, exhibits potent lethality affecting both hematological and respiratory systems primarily through theFormula:C270H413N69O79S4Purity:98%Color and Shape:SolidMolecular weight:6017.84ShK toxin
CAS:ShK toxin, isolated from the Caribbean sea anemone (Stichodactyla helianthus), is an inhibitor of the voltage-dependent potassium channel (Kv1.3 channel).Formula:C169H274N54O48S7Purity:98%Color and Shape:SolidMolecular weight:4054.8Dendrotoxin K
CAS:Dendrotoxin K blocks Kv1.1 channels, modulating glutamate release in CA3 neurons by controlling presynaptic spike timing.Formula:C294H462N84O75S6Color and Shape:SolidMolecular weight:6559.66δ-Dendrotoxin
CAS:δ-Dendrotoxin is a potassium (K+) channel blocker derived from black mamba snake venom and is utilized in neurological disease research [1].Formula:C296H452N82O76S6Purity:98%Color and Shape:SolidMolecular weight:6567.65Iberiotoxin
CAS:Selective blocker of the big conductance Ca2+-activated K+ channel.Formula:C179H274N50O55S7Purity:98%Color and Shape:SolidMolecular weight:4230ADWX 1
Potent KV1.3 blocker, IC50: 0.0019 nM; less effective on KV1.1. Curbs CD4+ T cell activation; eases rat multiple sclerosis model.Formula:C169H281N57O46S7Purity:98%Color and Shape:SolidMolecular weight:4071.86BmP02
BmP02, a compound isolated from Chinese scorpion (Buthus martensi Karsch) venom, acts as a selective Kv1.3 channel blocker and a highly-selective Kv4.2Formula:C115H182N36O41S7Purity:98%Color and Shape:SolidMolecular weight:2949.35Noxiustoxin
CAS:Noxiustoxin, a toxin extracted from the venom of the Mexican scorpion Centruroides noxius, inhibits both the voltage-dependent potassium channel (Kv1.3, IC50 =Formula:C174H286N52O54S7Purity:98%Color and Shape:SolidMolecular weight:4195Pandinotoxin Kα
CAS:Pandinotoxin Kα, a chemical compound extracted from the emperor scorpion (Pandinus imperator) venom, functions as an inhibitor of the A-type potassium channel [Formula:C169H267N53O48S7Purity:98%Color and Shape:SolidMolecular weight:4033.71Tertiapin-RQ
Tertiapin-RQ, an inward rectifier potassium (K+) channel-blocking peptide, exhibits antidepressant effects [1].Formula:C106H175N37O25S4Purity:98%Color and Shape:SolidMolecular weight:2496.02Tertiapin LQ
Kir1.1 channel blocker, 250x selective; Kd: Kir1.1 (1.1 nM), Kir3.1/3.2 (274 nM), Kir3.1/3.4 (361 nM). Tertiapin-Q derivative.Formula:C106H179N33O24S4Purity:98%Color and Shape:SolidMolecular weight:2428.03Jingzhaotoxin-XII TFA
Jingzhaotoxin-XII (JzTx-XII) TFA is a specific inhibitor of the Kv4.1 channel, exhibiting an IC50 of 0.363 μM. It interacts with the channel by altering gating behavior.Color and Shape:Odour SolidBDS-I
CAS:BDS-I, a marine toxin derived from Anemonia sulcata, functions as a selective inhibitor of the potassium channel, specifically targeting Kv3.4.Formula:C210H297N57O56S6Purity:98%Color and Shape:SolidMolecular weight:4708.346-FAM-AEEAC-SHK TFA
6-FAM-AEEAC-SHK TFA, a peptide neurotoxin derived from Stichodactyla helianthus and conjugated with a fluorescent marker, selectively blocks voltage-gated potassium channels (kv1.1 and kv1.2). By prolonging action potentials, it interferes with neural signal conduction, making it valuable in neuroscience research.Formula:C196H295N55O57S7·xCHF3O2Color and Shape:SolidMolecular weight:4558.23 (free acid)Aekatperone
Aekatperone, a reversible KATP channel inhibitor, exhibits an IC50 of 9 μM. It is utilized in research related to congenital hyperinsulinism (CHI).Formula:C20H25N5O2SColor and Shape:SolidMolecular weight:399.51Hemitoxin
Hemitoxin, a scorpion-venom peptide, functions as a K+ channel blocker and selectively inhibits rat Kv1.1, Kv1.2, and Kv1.3 channels expressed in XenopusFormula:C159H259N49O49S8Purity:98%Color and Shape:SolidMolecular weight:3897.58GsAF-I
GsAF-I is a potent blocker of Na_v and hERG1 channels, exhibiting half-maximal inhibitory concentrations (IC50s) of 0.36 μM (Na_v 1.1), 0.6 μM (Na_v 1.2), 1.28Formula:C160H244N46O42S7Purity:98%Color and Shape:SolidMolecular weight:3708.39Heteropodatoxin-2
CAS:Heteropodatoxin-2, a 30-amino acid peptide, inhibits the Kv4.2 current in Xenopus laevis oocytes through a voltage-dependent mechanism, exhibiting reducedFormula:C144H207N39O46S6Purity:98%Color and Shape:SolidMolecular weight:3412.81Tertiapin-Q acetate
Tertiapin-Q acetate is a bee toxin derivative that inhibits BK-type K(+) channels in a concentration-dependent manner.Formula:C108H179N35O26S4Purity:96.44%Color and Shape:SolidMolecular weight:2512.06Phe-Met-Arg-Phe amide trifluoroacetate
CAS:Phe-met-arg-phe amide trifluoroacetate is an activator of K+ current with an ED50 of 23nm on the fundus nerve.Formula:C33H44F6N8O8SPurity:98%Color and Shape:SolidMolecular weight:826.81
