Potassium Channel
Potassium channels are a diverse group of membrane proteins that facilitate the flow of potassium ions (K+) across the cell membrane. These channels play a crucial role in maintaining the resting membrane potential, regulating cell volume, and controlling the excitability of neurons and muscle cells. Potassium channels are involved in various physiological processes, including cardiac rhythm regulation, insulin secretion, and neurotransmitter release. Dysregulation of potassium channels is linked to conditions such as arrhythmias, epilepsy, and hypertension. At CymitQuimica, we offer a wide range of potassium channel modulators to support your research in electrophysiology, cardiovascular health, and neurobiology.
Found 304 products of "Potassium Channel"
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AmmTX3
KV4 channel blocker that inhibits A-type K+ current in mouse neurons; requires DPP6 and DPP10 for effect.Formula:C158H262N50O48S6Purity:98%Color and Shape:SolidMolecular weight:3822.47δ-Dendrotoxin
CAS:δ-Dendrotoxin is a potassium (K+) channel blocker derived from black mamba snake venom and is utilized in neurological disease research [1].Formula:C296H452N82O76S6Purity:98%Color and Shape:SolidMolecular weight:6567.65Noxiustoxin
CAS:Noxiustoxin, a toxin extracted from the venom of the Mexican scorpion Centruroides noxius, inhibits both the voltage-dependent potassium channel (Kv1.3, IC50 =Formula:C174H286N52O54S7Purity:98%Color and Shape:SolidMolecular weight:4195BKCa activator-1
BKCa activator-1 (Compound 51b) is an orally active activator of BKCa calcium-activated potassium channels with an EC50 of 2.82 μM. It promotes K+ efflux, leading to cell membrane hyperpolarization and inhibition of smooth muscle contraction. In a spontaneous hypertensive rat (SHR) model, it alleviates urinary incontinence and exhibits antitussive effects in a guinea pig cough model.Formula:C22H23F7N2O3Color and Shape:SolidMolecular weight:496.418Lei-Dab7 TFA
Lei-Dab7 TFA blocks SK2 channels with 3.8 nM affinity, is >200x selective, and enhances LTP in rat hippocampus.Formula:C143H237F3N46O41S6Color and Shape:SolidMolecular weight:3506.08Apamin
CAS:Apamin: 18-amino acid bee venom peptide, blocks SK channels, anti-inflammatory, anti-fibrotic, strongly basic.Formula:C79H131N31O24S4Purity:98%Color and Shape:SolidMolecular weight:2027.34Ssm spooky toxin
Ssm Spooky Toxin, derived from Scolopendra mutilans, exhibits potent lethality affecting both hematological and respiratory systems primarily through theFormula:C270H413N69O79S4Purity:98%Color and Shape:SolidMolecular weight:6017.84Agitoxin-2
CAS:Potent Shaker K+ channel blocker (Ki = 0.64 nM). Also inhibits Kv1.3, Kv1.6 and Kv1.1 K+ channels (Ki values are 4, 37 and 44 pM respectively).Formula:C169H278N54O48S8Purity:98%Color and Shape:SolidMolecular weight:4090.87HG1 Toxin
HG1 Toxin is a peptide found in the venom of the scorpion Heterometrus fulvipes, known for its ability to inhibit the potassium channel Kv1.3 (potassium channel Kv1.3). Additionally, HG1 Toxin exhibits trypsin inhibitory activity (Ki=107 nM), making it useful for research into autoimmune diseases.Formula:C337H503N103O97S6Molecular weight:7736.59176RU-TRAAK-2
CAS:RU-TRAAK-2 reversibly inhibits TWIK-related K+ channel, inactive on Kv1.2, GIRK2, Slo1.
Formula:C19H17N3OSPurity:99.81%Color and Shape:SolidMolecular weight:335.42Tertiapin-RQ
Tertiapin-RQ, an inward rectifier potassium (K+) channel-blocking peptide, exhibits antidepressant effects [1].Formula:C106H175N37O25S4Purity:98%Color and Shape:SolidMolecular weight:2496.02Apamin acetate
Apamin acetate: Selective Ca2+-activated K+ channel blocker, 18-amino acid bee venom peptide, promotes synapse repair, anti-inflammatory.Purity:96.97%Color and Shape:SolidTertiapin
CAS:Tertiapin (reduced) is a synthetic bee venom peptide characterized by disulfide bonds between Cys3-Cys14 and Cys5-Cys18. It acts as an inhibitor of inward-rectifying potassium channels (potassium Channel) and can also block the activity of calcium-activated large conductance potassium channels. Tertiapin (reduced) is utilized in research related to diseases such as rheumatoid arthritis and multiple sclerosis.Formula:C106H180N34O23S5Color and Shape:SolidMolecular weight:2459.1Tertiapin-Q acetate
Tertiapin-Q acetate is a bee toxin derivative that inhibits BK-type K(+) channels in a concentration-dependent manner.Formula:C108H179N35O26S4Purity:96.44%Color and Shape:SolidMolecular weight:2512.06BmP02
BmP02, a compound isolated from Chinese scorpion (Buthus martensi Karsch) venom, acts as a selective Kv1.3 channel blocker and a highly-selective Kv4.2Formula:C115H182N36O41S7Purity:98%Color and Shape:SolidMolecular weight:2949.35Spinoxin
CAS:Spinoxin, a 34-residue peptide neurotoxin extracted from the venom of Heterometrus spinifer, is characterized by four disulfide bridges.Formula:C147H236N48O46S9Purity:98%Color and Shape:SolidMolecular weight:3700.33Tamapin
Tamapin, a venom peptide isolated from the Indian red scorpion (Mesobuthus tamulus) [1], selectively targets and blocks small-conductance Ca(2+)-activated KFormula:C146H238N44O41S6Purity:98%Color and Shape:SolidMolecular weight:3458.11KV1.3-IN-1
KV1.3-IN-1 (Compound trans-18), a selective KV1.3 channel inhibitor with IC50 values of 230 nM in Ltk cells and 26.12 nM in PHA-activated T-lymphocytes,Formula:C23H30N2O4SPurity:98%Color and Shape:SolidMolecular weight:430.56QO-58
CAS:QO-58 is a novel Kv7 activator (opener) that activates neuronal Kv7/KCNQ/M channels, danti-nociceptive effects on inflammatory painFormula:C18H8Cl2F4N4OPurity:99.17%Color and Shape:SolidMolecular weight:443.18Clamikalant sodium
CAS:Clamikalant sodium (HMR 1098) is an ATP-dependent potassium channel (KATP) cardiac-selective blocker, used in the study of arrhythmias.Formula:C19H21ClN3NaO5S2Purity:99.95%Color and Shape:SolidMolecular weight:493.96Ref: TM-T63330
1mg48.00€5mg90.00€10mg172.00€25mg346.00€50mg546.00€100mg855.00€200mg1,170.00€1mL*10mM (DMSO)99.00€
