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Potassium Channel

Potassium Channel

Potassium channels are a diverse group of membrane proteins that facilitate the flow of potassium ions (K+) across the cell membrane. These channels play a crucial role in maintaining the resting membrane potential, regulating cell volume, and controlling the excitability of neurons and muscle cells. Potassium channels are involved in various physiological processes, including cardiac rhythm regulation, insulin secretion, and neurotransmitter release. Dysregulation of potassium channels is linked to conditions such as arrhythmias, epilepsy, and hypertension. At CymitQuimica, we offer a wide range of potassium channel modulators to support your research in electrophysiology, cardiovascular health, and neurobiology.

Found 276 products of "Potassium Channel"

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  • Ropivacaine hydrochloride monohydrate

    CAS:
    <p>Ropivacaine hydrochloride monohydrate (LEA-103 HCl) is an anaesthetic agent and blocks impulse conduction through inhibiting sodium ion influx reversibly.</p>
    Formula:C17H29ClN2O2
    Purity:99.94% - 99.95%
    Color and Shape:White Solid
    Molecular weight:328.88
  • Cholesterol myristate

    CAS:
    <p>Cholesterol myristate, a natural steroid in Chinese medicine, affects GABAA, nicotinic receptors, and potassium channels.</p>
    Formula:C41H72O2
    Purity:99.65%
    Color and Shape:Solid
    Molecular weight:597.01
  • Quinidine sulfate dihydrate

    CAS:
    <p>Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitor</p>
    Formula:C40H54N4O10S
    Purity:99.85%
    Color and Shape:White To Light Yellow Crystal Powde
    Molecular weight:782.9
  • ML277

    CAS:
    <p>ML277 (CID-53347902) was identified as a potent activator of KCNQ1 channels (EC(50)=260 nM).</p>
    Formula:C23H25N3O4S2
    Purity:99.35%
    Color and Shape:Solid
    Molecular weight:471.59
  • APD668

    CAS:
    <p>APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119, respectively.</p>
    Formula:C21H24FN5O5S
    Purity:99.74% - 99.97%
    Color and Shape:Solid
    Molecular weight:477.51
  • Amifampridine

    CAS:
    <p>Amifampridine blocks nerve potassium channels, extends action potentials, boosts acetylcholine release, and treats rare muscle diseases.</p>
    Formula:C5H7N3
    Purity:99.82%
    Color and Shape:Slightly Beige Powder
    Molecular weight:109.13
  • TKIM

    CAS:
    <p>TKIM is a TWIK-related potassium channel 1 (TREK-1) inhibitor, binding to the pocket of the intermediate (IM) state of TREK-1.</p>
    Formula:C18H14ClN3O2S
    Purity:99.47%
    Color and Shape:Solid
    Molecular weight:371.84
  • ICA-069673

    CAS:
    <p>ICA-069673 is an activator of KCNQ2/Q3 potassium channel (IC50: 0.69 μM).</p>
    Formula:C11H6ClF2N3O
    Purity:99.04% - 99.68%
    Color and Shape:Solid
    Molecular weight:269.63
  • NS309

    CAS:
    <p>NS309 activates SK/KCa2, IK/KCa3.1 (0.12-1.2 μM EC50, 10-90 nM EC50), and Kv11.1 channels; doesn't affect BK/KCa1.1; modulates neuronal firing.</p>
    Formula:C8H4Cl2N2O2
    Purity:97.55%
    Color and Shape:Solid
    Molecular weight:231.04
  • BAPTA-AM

    CAS:
    <p>BAPTA-AM is a calcium chelator that is cell-permeable and selective, blocking hERG, hKv1.3, and hKv1.5 channels (IC50=1.3/1.45/1.23 μM).</p>
    Formula:C34H40N2O18
    Purity:98% - 99.47%
    Color and Shape:White Powder Or Crystalline Powder
    Molecular weight:764.68
  • Quinidine

    CAS:
    <p>Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.</p>
    Formula:C20H24N2O2
    Purity:97.03% - 99.99%
    Color and Shape:Crystals With 2 5 Mol Water Of Crystallization; Crystals From Dilute Alcohol Physical Description Crystals Or White Powder (Ntp 1992)
    Molecular weight:324.42
  • Talatisamine

    CAS:
    <p>Talatisamine and TEA mitigate Aβ oligomer effects on I(K), bolstering cell survival and reducing K(+) loss-induced apoptosis; promising for further study.</p>
    Formula:C24H39NO5
    Purity:98.62% - 99.44%
    Color and Shape:Solid
    Molecular weight:421.57
  • VU0134992

    CAS:
    <p>VU0134992 is an Kir4.1 blocker with an IC50 value of 0.97 μM</p>
    Formula:C20H31BrN2O2
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:411.38
  • Endoxifen (Z-isomer)

    CAS:
    <p>Endoxifen Z-isomer (EDX) is a key active metabolite of tamoxifen with higher affinity and specificity to estrogen receptors that inhibits aromatase activity.</p>
    Formula:C25H27NO2
    Purity:99.19% - 99.81%
    Color and Shape:Solid
    Molecular weight:373.49
  • Paederosidic acid methyl ester

    CAS:
    <p>Paederosidic acid methyl ester has antinociception, is possibly related to the pathway of NO-cGMP-ATP sensitive K(+) channels.</p>
    Formula:C19H26O12S
    Purity:99.67% - 99.91%
    Color and Shape:Solid
    Molecular weight:478.47
  • 20(S)-Ginsenoside Rg3

    CAS:
    <p>20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.</p>
    Formula:C42H72O13
    Purity:98.11% - 99.93%
    Color and Shape:Solid
    Molecular weight:785.01
  • KCNQ2/3 activator-1

    CAS:
    <p>KCNQ2/3 activator-1 is a Kv7.2/Kv7.3 (KCNQ2/3) potassium channel activator.</p>
    Formula:C23H29FN2O
    Purity:99.16% - 99.47%
    Color and Shape:Solid
    Molecular weight:368.49
  • 2,2,2-Trichloroethanol

    CAS:
    <p>2,2,2-Trichloroethanol is an agonist of the nonclassical K2P channels TREK-1 and TRAAK.</p>
    Formula:C2H3Cl3O
    Purity:99.74%
    Color and Shape:Liquid
    Molecular weight:149.4
  • Yoda 1

    CAS:
    <p>Yoda 1 is an agonist of the Piezo1 channel that agonizes human- and mouse-derived Piezo1. Yoda 1 is also an inhibitor of GlyT2. Cost-effective, quality assurance.</p>
    Formula:C13H8Cl2N4S2
    Purity:98% - 99.98%
    Color and Shape:Solid
    Molecular weight:355.27
  • Quinine hydrochloride dihydrate

    CAS:
    <p>Quinine hydrochloride dihydrate (Quinine HCl Dihydrate) is a white crystalline K+ channel blocker, used to treat malaria.</p>
    Formula:C20H24N2O2·HCl·2H2O
    Purity:99.91%
    Color and Shape:White To Light Yellow Crystal Powder
    Molecular weight:396.91