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Potassium Channel

Potassium Channel

Potassium channels are a diverse group of membrane proteins that facilitate the flow of potassium ions (K+) across the cell membrane. These channels play a crucial role in maintaining the resting membrane potential, regulating cell volume, and controlling the excitability of neurons and muscle cells. Potassium channels are involved in various physiological processes, including cardiac rhythm regulation, insulin secretion, and neurotransmitter release. Dysregulation of potassium channels is linked to conditions such as arrhythmias, epilepsy, and hypertension. At CymitQuimica, we offer a wide range of potassium channel modulators to support your research in electrophysiology, cardiovascular health, and neurobiology.

Found 276 products of "Potassium Channel"

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  • Kv2-IN-A1

    CAS:
    <p>Kv2-IN-A1 is an inhibitor of Kv2.1 and Kv2.2.</p>
    Formula:C20H17ClN4OS
    Purity:98.83%
    Color and Shape:Solid
    Molecular weight:396.89
  • Almitrine mesylate

    CAS:
    <p>Almitrine mesylate targets Ca2+-dependent K+ channels in rat cells, used for chronic lung hypoxemia.</p>
    Formula:C28H37F2N7O6S2
    Purity:99.96%
    Color and Shape:Coa
    Molecular weight:669.76
  • Azimilide Dihydrochloride

    CAS:
    <p>Azimilide Dihydrochloride (NE-10064 Dihydrochloride), a novel class III antiarrhythmic agent, blocks both the IKs and IKr with antiarrhythmic activity.</p>
    Formula:C23H30Cl3N5O3
    Purity:97.59% - ≥95%
    Color and Shape:Solid
    Molecular weight:530.88
  • ML365

    CAS:
    <p>ML365 is a novel selective small molecule inhibitor of TASK1(KCNK3).</p>
    Formula:C22H20N2O3
    Purity:98.78%
    Color and Shape:Solid
    Molecular weight:360.41
  • VU0071063

    CAS:
    <p>VU0071063 is a Kir6.2/SUR1 activator.</p>
    Formula:C18H22N4O2
    Purity:99.33%
    Color and Shape:Solid
    Molecular weight:326.39
  • Quinine dihydrochloride

    CAS:
    <p>Quinine dihydrochloride (Quinine bimuriate) is a primary alkaloid of various species of Cinchona (Rubiaceae).</p>
    Formula:C20H26Cl2N2O2
    Purity:99.79% - 99.97%
    Color and Shape:White Solid
    Molecular weight:397.34
  • Sematilide hydrochloride

    CAS:
    <p>Sematilide hydrochloride (CK-1752) is a class III antiarrhythmic. It is a selectively delayed rectifier K+ current (IKr) channel blocker.</p>
    Formula:C14H24ClN3O3S
    Purity:99.14%
    Color and Shape:Solid
    Molecular weight:349.87
  • Dofetilide

    CAS:
    <p>Dofetilide (UK 68789), a class III antiarrhythmic sulfonamide, blocks Ikr cardiac channels, prolongs action potential, and treats atrial fibrillation/flutter.</p>
    Formula:C19H27N3O5S2
    Purity:97.85% - 99.06%
    Color and Shape:Off-White Or Yellowish Crystalline Powder
    Molecular weight:441.56
  • AUT1

    CAS:
    <p>AUT1 (AUT-1) is a novel specific modulator of Kv3 channels (EC50: 4.7 and 4.9 uM for Kv3.1b and Kv3.2a).</p>
    Formula:C18H19N3O4
    Purity:99.8% - 99.95%
    Color and Shape:Solid
    Molecular weight:341.36
  • Iptakalim Hydrochloride

    CAS:
    <p>Iptakalim, a lipophilic para-amino compound, is a novel ATP-sensitive potassium channel (KATP) opener, as well as an α4β2-containing nicotinic acetylcholine</p>
    Formula:C9H22ClN
    Purity:98%
    Color and Shape:Solid
    Molecular weight:179.731
  • GSK369796 Dihydrochloride

    CAS:
    <p>GSK369796 Dihydrochloride (N-tert-butylisoquine),is an anti-malaria drug candidate.</p>
    Formula:C20H24Cl3N3O
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:428.78
  • PAP-1

    CAS:
    <p>PAP-1 (5-(4-Phenoxybutoxy)psoralen) is a selective, and orally active Kv1.3 blocker (EC50: 2 nM).</p>
    Formula:C21H18O5
    Purity:99.35% - 99.75%
    Color and Shape:White Solid
    Molecular weight:350.36
  • Nigericin sodium salt

    CAS:
    <p>Nigericin sodium salt, an antibiotic and NLRP3 activator from S. hygroscopicus, inhibits Golgi and gram-positive bacteria, blocking viral activation.</p>
    Formula:C40H67NaO11
    Purity:98.2% - 99.52%
    Color and Shape:Solid
    Molecular weight:746.94
  • Atpenin A5

    CAS:
    <p>Atpenin A5 is a potent and highly specific complex II inhibitor (IC50 ~10 nM).</p>
    Formula:C15H21Cl2NO5
    Purity:97.33% - 99.91%
    Color and Shape:Solid
    Molecular weight:366.24
  • LY 303511 hydrochloride

    CAS:
    <p>LY 303511 hydrochloride is a potent mTOR inhibitor</p>
    Formula:C19H19ClN2O2
    Purity:98.47%
    Color and Shape:Solid
    Molecular weight:342.82
  • Mitiglinide Calcium

    CAS:
    <p>Mitiglinide Calcium (KAD-1229) is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-</p>
    Formula:(C19H24NO3)2·Ca
    Purity:99.83%
    Color and Shape:White Crystal Posder
    Molecular weight:668.88
  • Flupirtine maleate

    CAS:
    <p>Flupirtine maleate (Katadolon maleate), a centrally acting non-opioid analgesia, is the salt form of Flupirtine. Flupirtine is an NMDA receptor antagonist.</p>
    Formula:C15H17FN4O2·C4H4O4
    Purity:99.5% - 99.9%
    Color and Shape:Off-White Crystalline Powder
    Molecular weight:420.39
  • Senicapoc

    CAS:
    <p>Senicapoc (ICA-17043) blocks Gardos channel, reduces RBC dehydration, IC50: 11 nM for rubidium flux, 30 nM for dehydration. Used in Sickle Cell therapy.</p>
    Formula:C20H15F2NO
    Purity:95.7% - 99.47%
    Color and Shape:Solid
    Molecular weight:323.34
  • E-4031 dihydrochloride

    CAS:
    <p>E-4031 is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)</p>
    Formula:C21H29Cl2N3O3S
    Purity:99.31% - 99.87%
    Color and Shape:Solid
    Molecular weight:474.44
  • Allocryptopine

    CAS:
    <p>Allocryptopine (Thalictrimine) induces muscle contraction and relaxation in urinary bladder and ileum, respectively.</p>
    Formula:C21H23NO5
    Purity:99.41% - ≥95%
    Color and Shape:Solid
    Molecular weight:369.41