Monoamine Transporter
Monoamine transporters are a group of membrane proteins responsible for the reuptake of monoamines—such as serotonin, dopamine, and norepinephrine—from the synaptic cleft back into presynaptic neurons. This process is crucial for regulating neurotransmitter levels and maintaining proper neurotransmission. Dysregulation of monoamine transporters is associated with various psychiatric and neurological disorders, including depression, anxiety, and Parkinson's disease. At CymitQuimica, we offer a range of monoamine transporter modulators to support your research in neurobiology, mental health, and pharmacology.
Found 31 products for "Monoamine Transporter".
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Nisoxetine hydrochloride
CAS:Nisoxetine hydrochloride is a noradrenaline transporter (NET) inhibitorFormula:C17H21NO2·HClPurity:99.21%Color and Shape:White SolidMolecular weight:307.82VMAT2-IN-I HCl
CAS:VMAT2-IN-I HCl is an inhibitor of vesicular monoamine transporter-2. It also has 15- fold greater affinity than GZ- 793A.Formula:C25H32ClF4NO4Purity:98%Color and Shape:SolidMolecular weight:521.97Imipramine pamoate
CAS:Imipramine pamoate, a potent antidepressant [1] [2], is a chemical compound widely recognized for its efficacy in treating depressive disorders.Formula:C61H64N4O6Color and Shape:SolidMolecular weight:949.18GZ-11608
CAS:GZ-11608, a selective and potent inhibitor of vesicular monoamine transporter-2 (VMAT2), presents a high affinity with a Ki value of 25 nM. It effectively reduces dopamine release induced by methamphetamine from isolated synaptic vesicles in brain dopaminergic neurons. GZ-11608 also demonstrates rapid penetration into the brain without exhibiting neurotoxicity, making it a valuable compound for researching methamphetamine use disorder [1].Formula:C19H25NOColor and Shape:SolidMolecular weight:283.41(2S,3S,11bR)-Dihydrotetrabenazine
CAS:(2S,3S,11bR)-Dihydrotetrabenazine ((2S,3S,11bR)-DHTBZ) is a highly selective inhibitor of vesicular monoamine transporter 2 (VMAT2) with a Ki value of 593 nM. It suppresses the vesicular transport of monoamine neurotransmitters, such as dopamine and serotonin, leading to reduced release into the synaptic cleft. This compound holds potential for research in Huntington's disease and other hyperkinetic movement disorders.Formula:C19H29NO3Color and Shape:SolidMolecular weight:319.44F3288-0031
CAS:F3288-0031 is an allosteric inhibitor of the norepinephrine transporter (NET), demonstrating a 73.5% inhibition rate at a concentration of 20 µM. It binds to NET, stabilizing its inward-open state, and shows preferential inhibitory activity against NET/SERT, with a pIC50 of 5.9. No off-target functional activity has been detected for F3288-0031. Furthermore, it exhibits significant antidepressant-like efficacy without interfering with motor functions. This compound is applicable in the study of depression and related neuropsychiatric disorders.Formula:C24H32N2O3Molecular weight:396.533-Bromoamphetamine hydrochloride
CAS:3-Bromoamphetamine hydrochloride is a para-substituted amphetamine that functions as a monoamine releaser.Formula:C9H13BrClNColor and Shape:SolidMolecular weight:250.563DLX48
CAS:DLX48 is a transporter inhibitor that binds to the active site of the LeuBAT (Δ13 mutant) transporter. It can traverse the blood-brain barrier and presents a low risk of drug interactions related to cytochrome P450. DLX48 is applicable in research on major depressive disorder.Formula:C18H20N2OSMolecular weight:312.43Valbenazine tosylate
CAS:Valbenazine tosylate, the tosylate salt of valbenazine, is a vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki value of 150 nM while displaying noFormula:C38H54N2O10S2Purity:98%Color and Shape:SolidMolecular weight:762.97Lafadofensine (D-(-)-Mandelic acid)
Lafadofensine D-(-)-Mandelic acid is a monoamines reuptake inhibitor with adequate effects when administered short-term.Formula:C32H32F2N2O6Color and Shape:SolidMolecular weight:578.6(+)-Tetrabenazine
CAS:(+)-Tetrabenazine ((3R,11bR)-Tetrabenazine) is a reversible vesicular monoamine transporter 2 (VMAT-2) inhibitor, inhibits transport by VMAT2 with 10-foldFormula:C19H27NO3Purity:98.69%Color and Shape:SolidMolecular weight:317.42
