Sodium Channel
Found 258 products of "Sodium Channel"
N-Formylguanidine
CAS:Controlled ProductFormula:C2H5N3OColor and Shape:Off-WhiteMolecular weight:87.086-(Propylamino)-2-hydroxy-N-(2,6-dimethylphenyl)hexanamide
Controlled ProductApplications 6-(Propylamino)-2-hydroxy-N-(2,6-dimethylphenyl)-hexanamide is a derivative of Bupivacaine (B689560), a sodium channel blocker, local anesthetic.
References Wilson, T.D., et al.: Anal. Profiles Drug Subs., 19, 59 (1990), McClellan, K.J., et al.: Drugs, 56, 355 (1998),Formula:C17H28N2O2Color and Shape:NeatMolecular weight:292.4163-Hydroxy-4-phenylbenzoic Acid
CAS:Controlled ProductApplications 3-Hydroxy-4-phenylbenzoic Acid is a useful reagent for the preparation of spiro[3,4-dihydro-2H-pyrrolo[1,2-a]pyrazine-1,4'-piperidine] derivatives as modulators of sodium ion channel.
References Hadida Ruah, S. S., et al.: U.S. Pat. Appl. Publ. (2012), US 20120196869 A1Formula:C13H10O3Color and Shape:NeatMolecular weight:214.221,2,4-Oxadiazol-3-amine
CAS:Controlled ProductApplications 1,2,4-oxadiazol-3-amine (cas# 39512-64-6) is a useful research chemical.
Formula:C2H3N3OColor and Shape:NeatMolecular weight:85.06Pentisomide
CAS:Controlled ProductApplications Pentisomide is a sodium channel blocker; derivative of disopyramide. Antiarrhythmic (class I).
References Kuhlkamp, V., et al.: Int. J. Cardiol., 36, 69 (1992), Yuan, S., et al.: Cardiovasc. Drug Rev., 11, 74 (1993)Formula:C19H33N3OColor and Shape:NeatMolecular weight:319.483-Deoxyyunaconitine
CAS:Controlled ProductApplications 3-Deoxyyunaconitine is a metabolite of Aconitine (A189875), a neurotoxin that binds, activates tetrodotoxin-sensitive Na+ channels and prolongs the opening of the sodium-ion channel by suppressing conformational changes.
References Derbre, S., et al.: Anal. Bioanal. Chem., 398, 1747 (2010), Li, M., et al.: J. Pharm. Biomed. Anal., 53, 1063 (2010),Formula:C35H49NO10Color and Shape:NeatMolecular weight:643.76Clopamide
CAS:Clopamide (Brinaldix) is a piperidine and sulfamoylbenzamide-based diuretic with thiazide-like diuretic activity.Formula:C14H20ClN3O3SPurity:99.71%Color and Shape:White To Yellowish Crystalline PowderMolecular weight:345.84Halofuginone
CAS:Halofuginone (RU-19110) inhibits prolyl-tRNA synthetase (Ki=18.3 nM), down-regulates Smad3, and blocks TGF-β at 10 ng/ml.Formula:C16H17BrClN3O3Purity:99.53%Color and Shape:Off-White SolidMolecular weight:414.68Ref: TM-T6856
1mg34.00€5mg82.00€1mL*10mM (DMSO)92.00€10mg116.00€25mg227.00€50mg344.00€100mg517.00€500mg1,134.00€DPI 201-106
CAS:DPI 201-106: cardioselective h1 Na channel inhibitor, enhances heart contraction, blocks potassium and calcium currents.Formula:C29H30N4O2Purity:99.94%Color and Shape:SolidMolecular weight:466.57Phenamil
CAS:Phenamil is an inhibitor of epithelial sodium channels, activates the osteomorphin protein pathway to promote bone repair and induces significant fat formation.Formula:C12H12ClN7OPurity:99.07%Color and Shape:SolidMolecular weight:305.72(5R)-BW-4030W92
CAS:(5R)-BW-4030W92 is the R-type of BW-4030W92, the active enantiomer.Formula:C11H9Cl2FN4Purity:98.27%Color and Shape:SolidMolecular weight:287.12NHE3-IN-2
CAS:NHE3-IN-2 is an inhibitor of NHE3 (Na+/H+ exchanger-3), applicable for treating hypertension, thrombosis, and ischaemic diseases.Formula:C15H12ClN5Color and Shape:SolidMolecular weight:297.74PF 05089771 tosylate
CAS:PF-05089771 inhibits Nav1.7 channels (IC50: 11-33 nM), selective over Nav1.1-1.6/1.8, Ca+, K+ channels, TRPV1; 1000x affinity for half-inactivated state.Formula:C18H12Cl2FN5O3S2·C7H8O3SPurity:98.55%Color and Shape:SolidMolecular weight:672.56GNE-0439
CAS:GNE-0439 is a Nav1.7-selective inhibitor (IC50 0.34 μM), also targeting Nav1.5 and mutant N1742K channels, valuable for ion channel research.Formula:C21H31NO3Purity:99.60%Color and Shape:SolidMolecular weight:345.48Ref: TM-T11437
1mg154.00€5mg371.00€1mL*10mM (DMSO)409.00€10mg620.00€25mg1,305.00€50mg1,783.00€100mg2,250.00€Sodium Channel inhibitor 2
CAS:Sodium Channel inhibitor 2 is a blocker of sodium channel.Formula:C26H25Cl2N3OPurity:98%Color and Shape:SolidMolecular weight:466.4E 0747
CAS:E 0747 is an antiarrhythmic agent of class 1C type. E-0747 suppresses arrhythmia by inhibiting the Na channels of cardiac cells.
Formula:C21H28ClN3O4Purity:95.17%Color and Shape:SolidMolecular weight:421.92GX-674
CAS:GX-674 is a highly potent and selective voltage-gated sodium channel 1.7 (Nav1.7) antagonist with an IC50 value of 0.1 nM measured at -40 mV for the study ofFormula:C21H13ClF2N6O3S2Purity:98.60%Color and Shape:SolidMolecular weight:534.95Halofuginone hydrobromide
CAS:Halofuginone specifically inhibits collagen type I and MMP-2 gene expression, which may result in the suppression of angiogenesis and tumor cell growth.Formula:C16H17BrClN3O3·HBrPurity:97.01% - 99.73%Color and Shape:SolidMolecular weight:495.59Ref: TM-T3524
1mg34.00€2mg49.00€5mg74.00€1mL*10mM (DMSO)84.00€10mg106.00€25mg207.00€50mg310.00€100mg469.00€500mg897.00€GX-585
CAS:GX-585 is a novel potent inhibitor of NaV1.7 and highly selective against NaV1.5, having limited selectivity against NaV1.1 and NaV1.2.Formula:C24H25Cl2FN4O3SPurity:99.02% - 99.03%Color and Shape:SolidMolecular weight:539.45GDC-0276
CAS:GDC-0276 is an orally active, selective, and potent NaV1.7 inhibitor that can be used for the study of pain-related diseases.Formula:C24H31FN2O4SPurity:99.77%Color and Shape:SolidMolecular weight:462.58
