Sodium Channel
Sodium channels are essential membrane proteins that allow the passage of sodium ions (Na+) across the cell membrane, generating and propagating electrical signals in neurons, muscle cells, and other excitable tissues. These channels are vital for the initiation and conduction of action potentials, making them crucial in processes such as nerve impulse transmission, muscle contraction, and cardiac function. Dysregulation of sodium channels can lead to neurological disorders, arrhythmias, and chronic pain conditions. At CymitQuimica, we provide a variety of sodium channel modulators to support your research in neurobiology, cardiology, and pain management.
Found 259 products of "Sodium Channel"
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Anthopleurin-A
CAS:Anthopleurin-A, a sodium channel toxin, is selective for cardiac channels and has a cardiotonic effect. It can be isolated from the sea anemone [1] [2].Formula:C220H326N64O67S6Color and Shape:SolidMolecular weight:5131.72PF-04856264
CAS:PF-04856264 is a Nav1.7 blocker.,modulates intracellular Ca 2+ signaling and chondrocyte secretome, raises the threshold of mechanical pain analgesic.Formula:C20H15N5O3S2Purity:97.43%Color and Shape:SolidMolecular weight:437.5Ref: TM-T33943
1mg50.00€5mg105.00€10mg170.00€25mg340.00€50mg532.00€100mg893.00€1mL*10mM (DMSO)117.00€Ethacizine hydrochloride
CAS:Ethacizine hydrochloride (NIK-244) has antiarrhythmic activity and can be used to study arrhythmias and myocardial infarction.Formula:C22H28ClN3O3SPurity:98.08% - 98.08%Color and Shape:SolidMolecular weight:449.9910,11-Dihydro-10-hydroxycarbamazepine-d4
CAS:10,11-Dihydro-10-hydroxycarbamazepine-d4 is a deuterated compound of 10,11-Dihydro-10-hydroxycarbamazepine.Formula:C15H10D4N2O2Molecular weight:258.31AM-2099
CAS:AM-2099 is a selective voltage-gated sodium channel Nav1.7 inhibitor used in pain research.Formula:C19H13F3N4O3S2Color and Shape:SolidMolecular weight:466.46Bulleyaconitine A
CAS:Bulleyaconitine A, an analgesic and antiinflammatory drug isolated from Aconitum plants, has several potential targets, such as voltage-gated Na+ channels.Formula:C35H49NO9Purity:99.56% - 99.76%Color and Shape:SolidMolecular weight:627.76Dibucaine hydrochloride
CAS:Dibucaine hydrochloride (Cinchocaine hydrochloride), a long-acting local amide anestheticsis, is usually used for surface anesthesia.Formula:C20H30ClN3O2Purity:99.66%Color and Shape:White PowderMolecular weight:379.92Mexiletine-d6 hydrochloride
CAS:Mexiletine D6 hydrochloride is a non-selective voltage-gated sodium channel blocker,is a Class IB antianhythmic.Formula:C11H18ClNOPurity:98%Color and Shape:SolidMolecular weight:221.763,3-Diethylthiacarbocyanine iodide
CAS:3, 3-diethylthiacarbocyanine iodide is a cyanine dye. Can be used for photochemical methods.Formula:C21H21IN2S2Purity:99.79%Color and Shape:SolidMolecular weight:492.44Mepivacaine
CAS:Mepivacaine (Carbocaine) is an amide local anesthetic, blocking sodium channels for nerve blocks and epidurals.Formula:C15H22N2OPurity:99.86%Color and Shape:SolidMolecular weight:246.35Triamterene D5
CAS:Triamterene D5 is a deuterium-labeled Triamterene and can block epithelial Na+ channel (ENaC) in a voltage-dependent manner, used as a mild diuretic.Formula:C12H11N7Purity:98%Color and Shape:SolidMolecular weight:258.29BI-9627
CAS:BI-9627 is an inhibitor of sodium-hydrogen exchanger isoform 1 (NHE1) (EC50: 31 nM).Formula:C16H19F3N4O2Purity:99.77%Color and Shape:SolidMolecular weight:356.34Poneratoxin acetate
Poneratoxin acetate is a neurotoxic peptide and modulator of NaV1.6/NaV1.7, lowering the activation threshold of voltage-gated sodium channels and causing pain.Formula:C129H215N33O31S·xC2H4O2Color and Shape:SolidMolecular weight:2756.35 (free base)Nicainoprol
CAS:Nicainoprol (RU-42924) is a fast-sodium-channel blocking drug. Nicainoprol is a potent antiarrhythmic agent.Formula:C21H27N3O3Purity:99.54%Color and Shape:SolidMolecular weight:369.46Ref: TM-T4539
1mg133.00€5mg326.00€10mg485.00€25mg770.00€50mg1,035.00€100mg1,395.00€1mL*10mM (DMSO)333.00€Ropivacaine hydrochloride monohydrate
CAS:Ropivacaine hydrochloride monohydrate (LEA-103 HCl) is an anaesthetic agent and blocks impulse conduction through inhibiting sodium ion influx reversibly.Formula:C17H29ClN2O2Purity:99.94% - 99.95%Color and Shape:White SolidMolecular weight:328.88GNE-131
CAS:GNE-131 is a potent and specific inhibitor of human sodium channel NaV1.7 (IC50: 3 nM).Formula:C23H30N4O3SPurity:98.54% - 99.59%Color and Shape:SolidMolecular weight:442.57Ref: TM-TQ0014
1mg105.00€5mg250.00€10mg356.00€25mg597.00€50mg835.00€100mg1,108.00€1mL*10mM (DMSO)268.00€Flecainide acetate
CAS:Flecainide acetate (R-818) is a class Ic antiarrhythmic agent used to prevent and treat tachyarrhythmias (abnormal fast rhythms of the heart).Formula:C19H24F6N2O5Purity:99.42%Color and Shape:SolidMolecular weight:474.39Fosphenytoin disodium
CAS:Fosphenytoin disodium (ACC-9653) is a prodrug of phenytoin that is rapidly converted to phenytoin, a voltage-gated sodium channel blockerFormula:C16H13N2Na2O6PPurity:99.97%Color and Shape:White Crystalline PowderMolecular weight:406.24DS-1971a
CAS:DS-1971a is a highly potent and selective NaV1.7 inhibitor. DS-1971a exhibits a favorable toxicological profile and analgesic effects.Formula:C20H21ClFN5O3SPurity:99.66%Color and Shape:SolidMolecular weight:465.93Cariporide
CAS:Cariporide (HOE-642), an NHE1 inhibitor, reduces human platelet degranulation, platelet-leukocyte aggregates, and GPIIb/IIIa activation.Formula:C12H17N3O3SPurity:95.4% - 99.88%Color and Shape:SolidMolecular weight:283.35
