Sodium Channel
Sodium channels are essential membrane proteins that allow the passage of sodium ions (Na+) across the cell membrane, generating and propagating electrical signals in neurons, muscle cells, and other excitable tissues. These channels are vital for the initiation and conduction of action potentials, making them crucial in processes such as nerve impulse transmission, muscle contraction, and cardiac function. Dysregulation of sodium channels can lead to neurological disorders, arrhythmias, and chronic pain conditions. At CymitQuimica, we provide a variety of sodium channel modulators to support your research in neurobiology, cardiology, and pain management.
Found 202 products of "Sodium Channel"
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Ancistrotecine B
<p>Ancistrotecine B (Compound 2), a Nav1.7 channel inhibitor (IC50: 0.73 μM), has been shown to alleviate inflammatory pain in mice [1].</p>Formula:C26H31NO4Purity:98%Color and Shape:SolidMolecular weight:421.53PF-06456384 trihydrochloride
CAS:<p>PF-06456384 trihydrochloride is a selective NaV1.7 inhibitor acting through protein-ligand binding. intravenous infusion and pain research.</p>Formula:C35H35Cl3F3N7O3S2Purity:99.16%Color and Shape:SolidMolecular weight:829.18Solpecainol
CAS:<p>solpecainol is a sodium channel blocker used in the study of neurological and cardiovascular diseases.</p>Formula:C18H23NO3Purity:99.71%Color and Shape:SoildMolecular weight:301.38Analgesic agent-2
<p>Analgesic Agent-2, a selective orally active inhibitor of the NaV1.8 channel, demonstrates an IC50 of 50.18 nM in HEK293 cells that stably express the human</p>Formula:C21H21ClF2N4O2Purity:98%Color and Shape:SolidMolecular weight:434.871-(1-Methyl-1h-pyrazol-4-yl)-ethanone
CAS:<p>1-(1-Methyl-1h-pyrazol-4-yl)-ethanone is a high purity biochemical reagent that can be used in research related to life sciences.</p>Formula:C6H8N2OPurity:99.92%Color and Shape:SolidMolecular weight:124.14Nav1.7-IN-18
<p>Nav1.7-IN-18 (Compound 31) is a Nav1.7 inhibitor with a Ki value of 4.9 nM and an IC50 of 13 nM, demonstrating analgesic effects in transgenic mice with inherited erythromelalgia (IEM).</p>Formula:C30H33Cl2F2NO4Color and Shape:SolidMolecular weight:580.49Myomodulin
CAS:<p>Myomodulin is a neuropeptide present in molluscs, insects, and gastropods.Myomodulin is present in two identified aplysia neurons that contain myomodulin A the</p>Formula:C36H67N11O8S2Purity:98%Color and Shape:SolidMolecular weight:846.12ASG-5ME
<p>ASG-5ME is a drug-antibody coupling targeting SLC44A4 that shows anti-tumor activity in xenograft models and may be used to study pancreatic and gastric cancer.</p>Purity:98.1% (SDS-PAGE); 98.5% (SEC-HPLC) - 98.1% (SDS-PAGE); 98.5% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.5 kDaZandatrigine
CAS:<p>Zandatrigine (NBI-921352) is a blocker of sodium channel protein type 8 subunit alpha and can be used in studies about nervous system pathologies of epilepsy</p>Formula:C22H25FN4O2S2Purity:99.98%Color and Shape:SolidMolecular weight:460.59Zoniporide hydrochloride
CAS:<p>Zoniporide hydrochloride: selective NHE-1 inhibitor, IC50 14 nM, >150x selectivity over other NHEs, inhibits platelet swelling (IC50 59 nM).</p>Formula:C17H17ClN6OPurity:99.68%Color and Shape:SolidMolecular weight:356.81ETD001
CAS:<p>ETD001 is a long-acting ENaC inhibitor with an IC50 value of 57.5 nM in HBE cells. It is applicable for research in cystic fibrosis.</p>Formula:C41H57F6N9O16Color and Shape:SolidMolecular weight:1045.935-Tridecanol
CAS:<p>5-Tridecanol blocks ion flux in sodium channels.</p>Formula:C13H28OPurity:97.87%Color and Shape:SolidMolecular weight:200.36NHE-1-IN-2
<p>NHE-1-IN-2 (compound 7g) is a potent NHE-1 inhibitor with an IC50 of 0.78 μM. It mitigates left ventricular systolic dysfunction in mouse models of heart failure.</p>Formula:C23H20ClN3O3Color and Shape:SolidMolecular weight:421.11932APETx2
CAS:<p>ASIC3 inhibitor; IC50: 63 nM (rat), 175 nM (human). Blocks NaV1.8, NaV1.2; analgesic for acid/inflammatory pain.</p>Formula:C196H280N54O61S6Purity:98%Color and Shape:SolidMolecular weight:4561.06Mambalgin 1
CAS:<p>ASIC1a inhibitor; IC50: 192 nM (human), 72 nM (dimer); inactive channel binding; selective; pain response delay.</p>Formula:C272H429N85O84S10Purity:98%Color and Shape:SolidMolecular weight:6554.51CL-424032
CAS:<p>CL-424032 is an inhibitor of sodium channels (sodium channel).</p>Formula:C12H7F3N4O2Color and Shape:SolidMolecular weight:296.21ProTx II
CAS:<p>Selective NaV1.7 inhibitor, alters activation, reduces current, 100x more selective for 1.7 over other Na+ channels.</p>Formula:C168H250N46O41S8Purity:98%Color and Shape:SolidMolecular weight:3826.59Indenebart
<p>Indenebart is a humanized IgG1λ2 monoclonal antibody targeting SNCA, with HumanIgG1lambda2, Isotype Control serving as the corresponding isotype control.</p>Color and Shape:Odour LiquidIon Channel Targeted Library
<p>A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;</p>Color and Shape:Odour SolidHuwentoxin-IV
CAS:<p>Selective NaV1.7 blocker; also inhibits NaV1.2, 1.3; less effect on NaV1.4, 1.5. Binds to neurotoxin site, traps voltage sensor. IC50: 26-338 nM.</p>Formula:C174H278N52O51S6Purity:98%Color and Shape:SolidMolecular weight:4106.79OD1
<p>Activates rat Nav1.7, human Nav1.4, rat Nav1.6 (EC50: 7, 10, 47 nM); minimal on Nav1.2, 1.3, 1.5 (EC50 >3 μM); blocks fast inactivation; triggers pain.</p>Formula:C308H466N90O95S8Purity:98%Color and Shape:SolidMolecular weight:7206.1Phrixotoxin 3
CAS:<p>Potent NaV blocker: IC50 - 0.6 nM (NaV1.2), 42 nM (NaV1.3), 72 nM (NaV1.5); voltage-dependent inhibition.</p>Formula:C176H269N51O48S6Purity:98%Color and Shape:SolidMolecular weight:4059.74Sodium Channel Targeted Library
<p>A unique collection of xnum sodium channel blockers and agonists for high throughput and high content screening;</p>Color and Shape:Odour SolidLifarizine FA
<p>Lifarizine FA is a sodium channel blocker used in the treatment of neurological disorders and cardiovascular diseases, study of stroke.</p>Formula:C30H34N4O2Purity:99.55%Color and Shape:SolidMolecular weight:482.62Benzonatate (PEGn)
CAS:<p>Benzonatate (PEGn) is a unique non-narcotic cough suppressant featuring sodium channel blocking properties and anesthetic effects on respiratory tract stretch receptors.</p>Formula:(C2H4O)nC12H17NO2Color and Shape:SolidGX 201
CAS:<p>GX 201 is a selective NaV1.7 inhibitor, IC50 of < 3.2 nM for hNaV1.7.</p>Formula:C25H27ClF4N2O4SPurity:99.81%Color and Shape:SolidMolecular weight:563Mepivacaine hydrochloride
CAS:<p>Mepivacaine hydrochloride (Mepivacaine HCl) is the hydrochloride salt form of mepivacaine, an amide derivative with local anesthetic properties.</p>Formula:C15H22N2O·HClPurity:98.76% - 99.94%Color and Shape:White Or Off White Crystalline PowderMolecular weight:282.81Amlenetug
<p>Amlenetug is a humanized IgG1κ antibody targeting SNCA, with its corresponding isotype control being HumanIgG1kappa, Isotype Control.</p>Color and Shape:Odour LiquidMexiletine-d6 hydrochloride
CAS:<p>Mexiletine D6 hydrochloride is a non-selective voltage-gated sodium channel blocker,is a Class IB antianhythmic.</p>Formula:C11H18ClNOPurity:98%Color and Shape:SolidMolecular weight:221.76Triamterene D5
CAS:<p>Triamterene D5 is a deuterium-labeled Triamterene and can block epithelial Na+ channel (ENaC) in a voltage-dependent manner, used as a mild diuretic.</p>Formula:C12H11N7Purity:98%Color and Shape:SolidMolecular weight:258.29BI-9627
CAS:<p>BI-9627 is an inhibitor of sodium-hydrogen exchanger isoform 1 (NHE1) (EC50: 31 nM).</p>Formula:C16H19F3N4O2Purity:99.77%Color and Shape:SolidMolecular weight:356.34Poneratoxin acetate
<p>Poneratoxin acetate is a neurotoxic peptide and modulator of NaV1.6/NaV1.7, lowering the activation threshold of voltage-gated sodium channels and causing pain.</p>Formula:C129H215N33O31S·xC2H4O2Color and Shape:SolidMolecular weight:2756.35 (free base)Ethacizine hydrochloride
CAS:<p>Ethacizine hydrochloride (NIK-244) has antiarrhythmic activity and can be used to study arrhythmias and myocardial infarction.</p>Formula:C22H28ClN3O3SPurity:98.08% - 98.08%Color and Shape:SolidMolecular weight:449.99Dibucaine hydrochloride
CAS:<p>Dibucaine hydrochloride (Cinchocaine hydrochloride), a long-acting local amide anestheticsis, is usually used for surface anesthesia.</p>Formula:C20H30ClN3O2Purity:99.66%Color and Shape:White PowderMolecular weight:379.92Bulleyaconitine A
CAS:<p>Bulleyaconitine A, an analgesic and antiinflammatory drug isolated from Aconitum plants, has several potential targets, such as voltage-gated Na+ channels.</p>Formula:C35H49NO9Purity:99.56% - 99.76%Color and Shape:SolidMolecular weight:627.76AM-2099
CAS:<p>AM-2099 is a selective voltage-gated sodium channel Nav1.7 inhibitor used in pain research.</p>Formula:C19H13F3N4O3S2Color and Shape:SolidMolecular weight:466.46PF-04856264
CAS:<p>PF-04856264 is a Nav1.7 blocker.,modulates intracellular Ca 2+ signaling and chondrocyte secretome, raises the threshold of mechanical pain analgesic.</p>Formula:C20H15N5O3S2Purity:97.43%Color and Shape:SolidMolecular weight:437.5Mepivacaine
CAS:<p>Mepivacaine (Carbocaine) is an amide local anesthetic, blocking sodium channels for nerve blocks and epidurals.</p>Formula:C15H22N2OPurity:99.35%Color and Shape:SolidMolecular weight:246.35Raxatrigine
CAS:<p>Raxatrigine (CNV 1014802) has been investigated for the treatment of Bipolar Disorder and Bipolar Depression.</p>Formula:C18H19FN2O2Purity:98% - 99.43%Color and Shape:SolidMolecular weight:314.35DS-1971a
CAS:<p>DS-1971a is a highly potent and selective NaV1.7 inhibitor. DS-1971a exhibits a favorable toxicological profile and analgesic effects.</p>Formula:C20H21ClFN5O3SPurity:99.66%Color and Shape:SolidMolecular weight:465.93A-803467
CAS:<p>A-803467 is a selective NaV1.8 channel blocker.</p>Formula:C19H16ClNO4Purity:96.94% - 98%Color and Shape:SolidMolecular weight:357.79Flecainide hydrochloride
CAS:<p>Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias.</p>Formula:C17H21ClF6N2O3Purity:97.79%Color and Shape:SolidMolecular weight:450.81Ropivacaine hydrochloride monohydrate
CAS:<p>Ropivacaine hydrochloride monohydrate (LEA-103 HCl) is an anaesthetic agent and blocks impulse conduction through inhibiting sodium ion influx reversibly.</p>Formula:C17H29ClN2O2Purity:99.94% - 99.95%Color and Shape:White SolidMolecular weight:328.88Fosphenytoin disodium
CAS:<p>Fosphenytoin disodium (ACC-9653) is a prodrug of phenytoin that is rapidly converted to phenytoin, a voltage-gated sodium channel blocker</p>Formula:C16H13N2Na2O6PPurity:99.97%Color and Shape:White Crystalline PowderMolecular weight:406.24Metergoline
CAS:<p>Metergoline (Methergoline) is a dopamine agonist and serotonin antagonist.</p>Formula:C25H29N3O2Purity:99.83% - 99.97%Color and Shape:SolidMolecular weight:403.52Rimeporide
CAS:<p>Rimeporide (EMD-87580) (EMD-87580) is a potent and selective Sodium hydrogen exchange 1 (NHE-1) inhibitor.</p>Formula:C11H15N3O5S2Purity:97.66%Color and Shape:SolidMolecular weight:333.38λ-Cyhalothrin
CAS:<p>λ-Cyhalothrin (Icon) is a type II synthetic pyrethroid insecticide featuring a high-efficiency, broad-spectrum formula with an α-cyano group.</p>Formula:C23H19ClF3NO3Purity:99.76%Color and Shape:SolidMolecular weight:449.85Flecainide acetate
CAS:<p>Flecainide acetate (R-818) is a class Ic antiarrhythmic agent used to prevent and treat tachyarrhythmias (abnormal fast rhythms of the heart).</p>Formula:C19H24F6N2O5Purity:99.42%Color and Shape:SolidMolecular weight:474.39Nicainoprol
CAS:<p>Nicainoprol (RU-42924) is a fast-sodium-channel blocking drug. Nicainoprol is a potent antiarrhythmic agent.</p>Formula:C21H27N3O3Purity:99.54%Color and Shape:SolidMolecular weight:369.46Pilsicainide HCl
CAS:<p>Pilsicainide HCl (SUN 1165) is a pure sodium channel blocker</p>Formula:C17H25ClN2OPurity:99.01% - 99.80%Color and Shape:SolidMolecular weight:308.85
