CymitQuimica logo
Sodium Channel

Sodium Channel

Sodium channels are essential membrane proteins that allow the passage of sodium ions (Na+) across the cell membrane, generating and propagating electrical signals in neurons, muscle cells, and other excitable tissues. These channels are vital for the initiation and conduction of action potentials, making them crucial in processes such as nerve impulse transmission, muscle contraction, and cardiac function. Dysregulation of sodium channels can lead to neurological disorders, arrhythmias, and chronic pain conditions. At CymitQuimica, we provide a variety of sodium channel modulators to support your research in neurobiology, cardiology, and pain management.

Found 258 products of "Sodium Channel"

Sort by

Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • Vormatrigine

    CAS:
    Vormatrigine effectively inhibits sodium channels (sodium channel).
    Formula:C16H12F6N4O2
    Color and Shape:Solid
    Molecular weight:406.28

    Ref: TM-T201328

    25mg
    1,458.00€
    50mg
    1,839.00€
    100mg
    2,322.00€
  • Nav1.8-IN-5

    CAS:
    Nav1.8-IN-5 (Example 1), a voltage-gated sodium channel Nav1.8 inhibitor, is applicable in the research of Nav1.8-mediated diseases including pain, pain-related disorders, and cardiovascular diseases (such as atrial fibrillation) [1].
    Formula:C23H15F4N3O2
    Color and Shape:Solid
    Molecular weight:441.38

    Ref: TM-T86969

    10mg
    To inquire
    50mg
    To inquire
  • Quinacainol dihydrochloride

    CAS:

    Quinacainol dihydrochloride (PK 10139 dihydrochloride) is the bis(2 hydrochloride) salt form of Quinacainol. It acts as an inhibitor of the sodium current, with an EC50 of 95 µM. This compound displays antiarrhythmic activity by modulating the electrophysiological properties of the heart.

    Formula:C21H32Cl2N2O
    Color and Shape:Solid
    Molecular weight:399.398

    Ref: TM-T204878

    10mg
    To inquire
    50mg
    To inquire
  • Olorigliflozin

    CAS:
    Olorigliflozin is a sodium glucose co-transporter (SGLT) inhibitor with antihyperglycemic properties.
    Formula:C23H27ClO7
    Color and Shape:Solid
    Molecular weight:450.909

    Ref: TM-T205428

    10mg
    To inquire
    50mg
    To inquire
  • ErSO-TFPy

    CAS:
    ErSO-TFPy activates the sodium ion channel TRPM4, resulting in an imbalance of intracellular calcium and sodium ions. It exhibits low nanomolar-level cytotoxicity (IC50 = 5-25 nM) by inducing necrosis in ERα+ breast cancer cell lines. Additionally, ErSO-TFPy shows antitumor activity in mouse models.
    Formula:C19H13F7N2O2
    Color and Shape:Solid
    Molecular weight:434.307

    Ref: TM-T205320

    10mg
    To inquire
    50mg
    To inquire
  • Nav1.7 blocker 1

    CAS:
    Nav1.7 blocker 1 (example 41), an effective Na+ channel (Na v) blocker, exhibits a potent IC50 value of 0.037 μM. This compound is utilized in pain research, encompassing neuropathic, postoperative, and inflammatory pain among others [1].
    Formula:C22H21FN4O4
    Molecular weight:424.42

    Ref: TM-T86964

    10mg
    To inquire
    50mg
    To inquire
  • Suzetrigine

    CAS:
    Suzetrigine (VX-548) is an oral NaV1.8 inhibitor with analgesic properties for acute pain research.
    Formula:C21H20F5N3O4
    Purity:98.08% - 99.27%
    Color and Shape:Solid
    Molecular weight:473.39

    Ref: TM-T69552

    1mg
    58.00€
    5mg
    114.00€
    10mg
    170.00€
    25mg
    266.00€
    300g
    129,112.00€
    50mg
    457.00€
    100mg
    747.00€
    200mg
    1,026.00€
    1mL*10mM (DMSO)
    118.00€
  • PF-06761281

    CAS:
    PF-06761281 is a partially selective sodium-coupled citrate transporter protein (NaCT/SLC13A5) inhibitor, oral, reducing plasma glucose concentration.
    Formula:C13H17NO6
    Color and Shape:Solid
    Molecular weight:283.28

    Ref: TM-T60547

    ne
    Discontinued
    Discontinued product