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Sodium Channel

Sodium Channel

Sodium channels are essential membrane proteins that allow the passage of sodium ions (Na+) across the cell membrane, generating and propagating electrical signals in neurons, muscle cells, and other excitable tissues. These channels are vital for the initiation and conduction of action potentials, making them crucial in processes such as nerve impulse transmission, muscle contraction, and cardiac function. Dysregulation of sodium channels can lead to neurological disorders, arrhythmias, and chronic pain conditions. At CymitQuimica, we provide a variety of sodium channel modulators to support your research in neurobiology, cardiology, and pain management.

Found 258 products of "Sodium Channel"

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  • Lubeluzole dihydrochloride

    CAS:
    Lubeluzole (dihydrochloride) acts as a neuroprotective agent by blocking neuronal voltage-gated sodium channels and also affects cardiac sodium channels, exhibiting both tonic and blocking effects. This compound is considered promising in the research of antiarrhythmic agents.
    Formula:C22H27Cl2F2N3O2S
    Color and Shape:Solid
    Molecular weight:506.44

    Ref: TM-T200178

    25mg
    1,458.00€
    50mg
    1,839.00€
    100mg
    2,322.00€
  • Nav1.8-IN-5

    CAS:
    Nav1.8-IN-5 (Example 1), a voltage-gated sodium channel Nav1.8 inhibitor, is applicable in the research of Nav1.8-mediated diseases including pain, pain-related disorders, and cardiovascular diseases (such as atrial fibrillation) [1].
    Formula:C23H15F4N3O2
    Color and Shape:Solid
    Molecular weight:441.38

    Ref: TM-T86969

    10mg
    To inquire
    50mg
    To inquire
  • Olisutrigine bromide

    CAS:
    Olisutrigine bromide is a sodium channel blocker used as an analgesic.
    Formula:C25H35BrN2
    Color and Shape:Solid
    Molecular weight:443.463

    Ref: TM-T205479

    10mg
    To inquire
    50mg
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  • Quinacainol dihydrochloride

    CAS:

    Quinacainol dihydrochloride (PK 10139 dihydrochloride) is the bis(2 hydrochloride) salt form of Quinacainol. It acts as an inhibitor of the sodium current, with an EC50 of 95 µM. This compound displays antiarrhythmic activity by modulating the electrophysiological properties of the heart.

    Formula:C21H32Cl2N2O
    Color and Shape:Solid
    Molecular weight:399.398

    Ref: TM-T204878

    10mg
    To inquire
    50mg
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  • Vormatrigine

    CAS:
    Vormatrigine effectively inhibits sodium channels (sodium channel).
    Formula:C16H12F6N4O2
    Color and Shape:Solid
    Molecular weight:406.28

    Ref: TM-T201328

    25mg
    1,458.00€
    50mg
    1,839.00€
    100mg
    2,322.00€
  • ErSO-TFPy

    CAS:
    ErSO-TFPy activates the sodium ion channel TRPM4, resulting in an imbalance of intracellular calcium and sodium ions. It exhibits low nanomolar-level cytotoxicity (IC50 = 5-25 nM) by inducing necrosis in ERα+ breast cancer cell lines. Additionally, ErSO-TFPy shows antitumor activity in mouse models.
    Formula:C19H13F7N2O2
    Color and Shape:Solid
    Molecular weight:434.307

    Ref: TM-T205320

    10mg
    To inquire
    50mg
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  • Suzetrigine

    CAS:
    Suzetrigine (VX-548) is an oral NaV1.8 inhibitor with analgesic properties for acute pain research.
    Formula:C21H20F5N3O4
    Purity:98.08% - 99.27%
    Color and Shape:Solid
    Molecular weight:473.39

    Ref: TM-T69552

    1mg
    55.00€
    5mg
    108.00€
    10mg
    161.00€
    25mg
    253.00€
    300g
    129,112.00€
    50mg
    434.00€
    100mg
    707.00€
    200mg
    973.00€
    1mL*10mM (DMSO)
    112.00€
  • PF-06761281

    CAS:
    PF-06761281 is a partially selective sodium-coupled citrate transporter protein (NaCT/SLC13A5) inhibitor, oral, reducing plasma glucose concentration.
    Formula:C13H17NO6
    Color and Shape:Solid
    Molecular weight:283.28

    Ref: TM-T60547

    ne
    Discontinued
    Discontinued product