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Calcium Channel

Calcium Channel

Calcium channels are membrane proteins that regulate the flow of calcium ions into and out of cells, which is essential for various cellular functions, including muscle contraction, neurotransmitter release, and gene expression. Dysregulation of calcium channel activity is associated with conditions such as hypertension, cardiac arrhythmias, and neurological disorders. At CymitQuimica, we provide a wide selection of calcium channel modulators to support your research in cardiovascular health, neurobiology, and signal transduction.

Found 525 products of "Calcium Channel"

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  • CymitQuimica logo
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    Cav 3.2 inhibitor 3

    Cav 3.2 inhibitor 3 is a potent inhibitor of the Cav3.2 T-type Ca2+channel (IC50: 0.1534 μM) and has a low binding affinity for D2 receptors.
    Formula:C32H37N3O2
    Color and Shape:Solid
    Molecular weight:495.66

    Ref: TM-T63350

  • SB-423557
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    SB-423557

    CAS:
    SB-423557 is an orally active antagonist of calcium-sensing receptor (CaR) with IC50 of 520 nM
    Formula:C28H36N2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:464.60

    Ref: TM-T12845

  • Emopamil
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    Emopamil

    CAS:
    Emopamil, a calcium channel inhibitor, reduces neuronal damage caused by ischemia.
    Formula:C23H30N2
    Color and Shape:Solid
    Molecular weight:334.5

    Ref: TM-T201608

  • SR 33805 oxalate
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    SR 33805 oxalate

    CAS:
    Ca2+ channel antagonist
    Formula:C34H42N2O9S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:654.77

    Ref: TM-T23391

  • RWJ 22108
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    RWJ 22108

    CAS:
    <p>RWJ 22108 is a bronchial-selective calcium channel (calcium channel) blocker that exhibits an IC50 of 5.7 nM in dog bronchial smooth muscle calcium-dependent contractions.</p>
    Formula:C27H30ClFN2O4S
    Color and Shape:Solid
    Molecular weight:533.06

    Ref: TM-T89985

  • CCR4 antagonist 2
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    CCR4 antagonist 2

    CAS:
    CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of CC chemokine receptor 4 (CCR4) that inhibits Treg
    Formula:C26H28Cl2N6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:511.45

    Ref: TM-T10713

  • CymitQuimica logo
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    Cav 3.2 inhibitor 2

    Cav 3.2 inhibitor 2 blocks T-type Ca2+ channels (IC50=0.09339 μM) and reduces mouse somatic/visceral pain. Used for intractable pain studies.
    Formula:C32H37F2N3O
    Color and Shape:Solid
    Molecular weight:517.65

    Ref: TM-T63606

  • Sesamodil
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    Sesamodil

    CAS:
    <p>Sesamodil (SD 3211) is a novel calcium antagonist that can be used to study hypertension.</p>
    Formula:C29H32N2O6S
    Purity:98.58% - 99.01%
    Color and Shape:Solid
    Molecular weight:536.64

    Ref: TM-T28759

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    Cav 3.2 inhibitor 1

    <p>Cav 3.2 inhibitor 1 targets T-type calcium channels, weakly binds D2 receptors, and aids physical and visceral pain research.</p>
    Formula:C32H39N3O
    Color and Shape:Solid
    Molecular weight:481.67

    Ref: TM-T63186

  • Mibefradil
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    Mibefradil

    CAS:
    <p>Mibefradil is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels (IC50s: 2.7 μM and 18.6 μM for T-type and L-type currents).</p>
    Formula:C29H38FN3O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:495.63

    Ref: TM-TQ0153

  • MP-010
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    MP-010

    CAS:
    <p>MP-010 is an FKBP12 ligand that regulates cytosolic calcium by stabilizing RyR channel activity. It facilitates functional improvement in SOD1G93A mice with amyotrophic lateral sclerosis (ALS), evidenced by enhanced motor coordination, increased integrity of neuromuscular junctions, and significantly higher spinal motor neuron survival rates. MP-010 is applicable for research in the field of neurological disorders.</p>
    Formula:C14H20N4O2S
    Color and Shape:Solid
    Molecular weight:308.399

    Ref: TM-T205471

  • CymitQuimica logo
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    PDE1-IN-4

    PDE1-IN-4: inhibits PDE1C/A/B with IC50s 10/145/354 nM, may help study idiopathic pulmonary fibrosis.
    Formula:C33H33N3O4
    Color and Shape:Solid
    Molecular weight:535.63

    Ref: TM-T63776

  • (rel)-Mirogabalin
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    (rel)-Mirogabalin

    CAS:
    (rel)-Mirogabalin ((rel)-DS5565) is an inhibitor of voltage-dependent calcium channels, specifically targeting the α2δ-1 subunit.
    Formula:C12H19NO2
    Color and Shape:Solid
    Molecular weight:209.28

    Ref: TM-T200506

  • CymitQuimica logo
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    T-Type calcium channel inhibitor 2

    Compound 6g inhibits T-type Ca channels (IC50: Cav3.1-31μM, Cav3.2-83μM), cytotoxic to A549 (IC50: 5μM) & HCT-116 cells (IC50: 6.4μM).
    Formula:C36H39FN4OS
    Color and Shape:Solid
    Molecular weight:594.78

    Ref: TM-T64203

  • Mibefradil dihydrochloride hydrate
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    Mibefradil dihydrochloride hydrate

    CAS:
    <p>Mibefradil dihydrochloride hydrate is a long-acting antihypertensive blocking high-voltage L calcium channels.</p>
    Formula:C29H42Cl2FN3O4
    Color and Shape:Solid
    Molecular weight:586.57

    Ref: TM-T64151

  • CymitQuimica logo
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    IAB15

    CAS:
    IAB15 is a potent inhibitor of T-type calcium channel that can be used in the research of epilepsy [1].
    Formula:C15H14F3NO2
    Color and Shape:Solid
    Molecular weight:297.27

    Ref: TM-T60648

  • TTA-P1
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    TTA-P1

    CAS:
    TTA-P1: potent T-type calcium channel inhibitor; impacts neuron firing, hormone secretion, cell growth; potential in absence epilepsy research.
    Formula:C19H27Cl2FN2O
    Color and Shape:Solid
    Molecular weight:389.33

    Ref: TM-T61747

  • PD-217014
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    PD-217014

    CAS:
    <p>PD-217014 is an α2δ ligand that exhibits visceral analgesic activity and can suppress visceral hypersensitivity. Its antihyperalgesic effects are dose-dependent.</p>
    Formula:C10H17NO2
    Color and Shape:Solid
    Molecular weight:183.25

    Ref: TM-T200642

  • CymitQuimica logo
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    IAA65

    CAS:
    <p>IAA65 is a potent inhibitor of T-type calcium channels, exhibiting an IC50 value of 18.9 μM, and holds potential for use in epilepsy research [1].</p>
    Formula:C16H13F6NO2
    Color and Shape:Solid
    Molecular weight:365.27

    Ref: TM-T61393

  • CAD204520
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    CAD204520

    CAS:
    CAD204520 functions as an inhibitor of SERCA (IC50 = 0.34 μM), specifically targeting mutations in the wild-type NOTCH1 protein associated with T-cell acute lymphoblastic leukemia (T-ALL) and mantle cell lymphoma (MCL).
    Formula:C23H32F3N3O2
    Color and Shape:Solid
    Molecular weight:439.51

    Ref: TM-T200097

  • NNC 55-0396
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    NNC 55-0396

    CAS:
    <p>NNC 55-0396: Selective T-type calcium channel blocker, IC50 6.8 μM, inhibits human ovarian cancer cell growth.</p>
    Formula:C30H40Cl2FN3O2
    Purity:99.00%
    Color and Shape:Solid
    Molecular weight:564.56

    Ref: TM-T12238

  • Leualacin
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    Leualacin

    CAS:
    Leualacin is a novel calcium blocker from Hapsidospora irregularis.
    Formula:C31H47N3O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:573.72

    Ref: TM-T25674

  • Verapamil EP Impurity C hydrochloride
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    Verapamil EP Impurity C hydrochloride

    CAS:
    <p>NSC-609249 hydrochloride, an impurity of Verapamil, is a calcium channel blocker with potent orally active properties. It also functions as a first-generation P-glycoprotein (P-gp) inhibitor.</p>
    Formula:C12H20ClNO2
    Color and Shape:Solid
    Molecular weight:245.75

    Ref: TM-T40591

    ne
    Discontinued
    Discontinued product
  • (Rac)-PD0299685
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    (Rac)-PD0299685

    CAS:
    <p>(Rac)-PD0299685 is a potent voltage-dependent calcium channel inhibitor for the study of retina-related diseases.</p>
    Formula:C10H21NO2
    Purity:97.20%
    Color and Shape:Solid
    Molecular weight:187.28

    Ref: TM-T68125

    ne
    Discontinued
    Discontinued product
  • Fostedil
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    Fostedil

    CAS:
    Fostedil enhances heart function, maintains blood flow during partial/total coronary occlusions, and lowers aortic pressure.
    Formula:C18H20NO3PS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:361.4

    Ref: TM-T27351

    25mg
    Discontinued
    50mg
    Discontinued
    100mg
    Discontinued
    Discontinued product