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Calcium Channel

Calcium Channel

Calcium channels are membrane proteins that regulate the flow of calcium ions into and out of cells, which is essential for various cellular functions, including muscle contraction, neurotransmitter release, and gene expression. Dysregulation of calcium channel activity is associated with conditions such as hypertension, cardiac arrhythmias, and neurological disorders. At CymitQuimica, we provide a wide selection of calcium channel modulators to support your research in cardiovascular health, neurobiology, and signal transduction.

Found 528 products of "Calcium Channel"

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  • EMD57033
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    EMD57033

    CAS:
    EMD57033 activates cardiac troponin C, enhances Ca2+ sensitivity to boost heart contraction.
    Formula:C22H23N3O4S
    Purity:97.24% - 99.11%
    Color and Shape:Solid
    Molecular weight:425.5

    Ref: TM-T25372

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    PDE1-IN-4

    PDE1-IN-4: inhibits PDE1C/A/B with IC50s 10/145/354 nM, may help study idiopathic pulmonary fibrosis.
    Formula:C33H33N3O4
    Color and Shape:Solid
    Molecular weight:535.63

    Ref: TM-T63776

  • Sesamodil
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    Sesamodil

    CAS:
    <p>Sesamodil (SD 3211) is a novel calcium antagonist that can be used to study hypertension.</p>
    Formula:C29H32N2O6S
    Purity:98.58% - 99.01%
    Color and Shape:Solid
    Molecular weight:536.64

    Ref: TM-T28759

  • PD-217014
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    PD-217014

    CAS:
    <p>PD-217014 is an α2δ ligand that exhibits visceral analgesic activity and can suppress visceral hypersensitivity. Its antihyperalgesic effects are dose-dependent.</p>
    Formula:C10H17NO2
    Color and Shape:Solid
    Molecular weight:183.25

    Ref: TM-T200642

  • Leualacin
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    Leualacin

    CAS:
    Leualacin is a novel calcium blocker from Hapsidospora irregularis.
    Formula:C31H47N3O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:573.72

    Ref: TM-T25674

  • Emopamil
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    Emopamil

    CAS:
    Emopamil, a calcium channel inhibitor, reduces neuronal damage caused by ischemia.
    Formula:C23H30N2
    Color and Shape:Solid
    Molecular weight:334.5

    Ref: TM-T201608

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    Cav 3.2 inhibitor 3

    Cav 3.2 inhibitor 3 is a potent inhibitor of the Cav3.2 T-type Ca2+channel (IC50: 0.1534 μM) and has a low binding affinity for D2 receptors.
    Formula:C32H37N3O2
    Color and Shape:Solid
    Molecular weight:495.66

    Ref: TM-T63350

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    Cav 3.2 inhibitor 1

    <p>Cav 3.2 inhibitor 1 targets T-type calcium channels, weakly binds D2 receptors, and aids physical and visceral pain research.</p>
    Formula:C32H39N3O
    Color and Shape:Solid
    Molecular weight:481.67

    Ref: TM-T63186

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    IAB15

    CAS:
    IAB15 is a potent inhibitor of T-type calcium channel that can be used in the research of epilepsy [1].
    Formula:C15H14F3NO2
    Color and Shape:Solid
    Molecular weight:297.27

    Ref: TM-T60648

  • TTA-P1
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    TTA-P1

    CAS:
    TTA-P1: potent T-type calcium channel inhibitor; impacts neuron firing, hormone secretion, cell growth; potential in absence epilepsy research.
    Formula:C19H27Cl2FN2O
    Color and Shape:Solid
    Molecular weight:389.33

    Ref: TM-T61747

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    T-Type calcium channel inhibitor 2

    Compound 6g inhibits T-type Ca channels (IC50: Cav3.1-31μM, Cav3.2-83μM), cytotoxic to A549 (IC50: 5μM) & HCT-116 cells (IC50: 6.4μM).
    Formula:C36H39FN4OS
    Color and Shape:Solid
    Molecular weight:594.78

    Ref: TM-T64203

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    Cav 3.2 inhibitor 2

    Cav 3.2 inhibitor 2 blocks T-type Ca2+ channels (IC50=0.09339 μM) and reduces mouse somatic/visceral pain. Used for intractable pain studies.
    Formula:C32H37F2N3O
    Color and Shape:Solid
    Molecular weight:517.65

    Ref: TM-T63606

  • SR 33805 oxalate
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    SR 33805 oxalate

    CAS:
    Ca2+ channel antagonist
    Formula:C34H42N2O9S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:654.77

    Ref: TM-T23391

  • Mibefradil dihydrochloride hydrate
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    Mibefradil dihydrochloride hydrate

    CAS:
    <p>Mibefradil dihydrochloride hydrate is a long-acting antihypertensive blocking high-voltage L calcium channels.</p>
    Formula:C29H42Cl2FN3O4
    Color and Shape:Solid
    Molecular weight:586.57

    Ref: TM-T64151

  • MP-010
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    MP-010

    CAS:
    <p>MP-010 is an FKBP12 ligand that regulates cytosolic calcium by stabilizing RyR channel activity. It facilitates functional improvement in SOD1G93A mice with amyotrophic lateral sclerosis (ALS), evidenced by enhanced motor coordination, increased integrity of neuromuscular junctions, and significantly higher spinal motor neuron survival rates. MP-010 is applicable for research in the field of neurological disorders.</p>
    Formula:C14H20N4O2S
    Color and Shape:Solid
    Molecular weight:308.399

    Ref: TM-T205471

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    IAA65

    CAS:
    <p>IAA65 is a potent inhibitor of T-type calcium channels, exhibiting an IC50 value of 18.9 μM, and holds potential for use in epilepsy research [1].</p>
    Formula:C16H13F6NO2
    Color and Shape:Solid
    Molecular weight:365.27

    Ref: TM-T61393

  • CCR4 antagonist 2
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    CCR4 antagonist 2

    CAS:
    CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of CC chemokine receptor 4 (CCR4) that inhibits Treg
    Formula:C26H28Cl2N6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:511.45

    Ref: TM-T10713

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    Cav 2.2/3.2 blocker 1

    <p>Compound 9e is a Cav 2.2/3.2 blocker; IC50: 1.22 μM &amp; 80 μM, respectively; penetrates CNS.</p>
    Formula:C28H30N2O3
    Color and Shape:Solid
    Molecular weight:442.55

    Ref: TM-T62586

  • (rel)-Mirogabalin
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    (rel)-Mirogabalin

    CAS:
    (rel)-Mirogabalin ((rel)-DS5565) is an inhibitor of voltage-dependent calcium channels, specifically targeting the α2δ-1 subunit.
    Formula:C12H19NO2
    Color and Shape:Solid
    Molecular weight:209.28

    Ref: TM-T200506

  • RWJ 22108
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    RWJ 22108

    CAS:
    <p>RWJ 22108 is a bronchial-selective calcium channel (calcium channel) blocker that exhibits an IC50 of 5.7 nM in dog bronchial smooth muscle calcium-dependent contractions.</p>
    Formula:C27H30ClFN2O4S
    Color and Shape:Solid
    Molecular weight:533.06

    Ref: TM-T89985