Calcium Channel
Calcium channels are membrane proteins that regulate the flow of calcium ions into and out of cells, which is essential for various cellular functions, including muscle contraction, neurotransmitter release, and gene expression. Dysregulation of calcium channel activity is associated with conditions such as hypertension, cardiac arrhythmias, and neurological disorders. At CymitQuimica, we provide a wide selection of calcium channel modulators to support your research in cardiovascular health, neurobiology, and signal transduction.
Found 573 products of "Calcium Channel"
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MP-010
CAS:MP-010 is an FKBP12 ligand that regulates cytosolic calcium by stabilizing RyR channel activity. It facilitates functional improvement in SOD1G93A mice with amyotrophic lateral sclerosis (ALS), evidenced by enhanced motor coordination, increased integrity of neuromuscular junctions, and significantly higher spinal motor neuron survival rates. MP-010 is applicable for research in the field of neurological disorders.Formula:C14H20N4O2SColor and Shape:SolidMolecular weight:308.399Mibefradil
CAS:Mibefradil is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels (IC50s: 2.7 μM and 18.6 μM for T-type and L-type currents).Formula:C29H38FN3O3Purity:98%Color and Shape:SolidMolecular weight:495.63CCR4 antagonist 2
CAS:CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of CC chemokine receptor 4 (CCR4) that inhibits TregFormula:C26H28Cl2N6OPurity:98%Color and Shape:SolidMolecular weight:511.45T-Type calcium channel inhibitor 2
Compound 6g inhibits T-type Ca channels (IC50: Cav3.1-31μM, Cav3.2-83μM), cytotoxic to A549 (IC50: 5μM) & HCT-116 cells (IC50: 6.4μM).Formula:C36H39FN4OSColor and Shape:SolidMolecular weight:594.78Cav 3.2 inhibitor 2
Cav 3.2 inhibitor 2 blocks T-type Ca2+ channels (IC50=0.09339 μM) and reduces mouse somatic/visceral pain. Used for intractable pain studies.Formula:C32H37F2N3OColor and Shape:SolidMolecular weight:517.65(rel)-Mirogabalin
CAS:(rel)-Mirogabalin ((rel)-DS5565) is an inhibitor of voltage-dependent calcium channels, specifically targeting the α2δ-1 subunit.Formula:C12H19NO2Color and Shape:SolidMolecular weight:209.28Cav 3.2 inhibitor 1
Cav 3.2 inhibitor 1 targets T-type calcium channels, weakly binds D2 receptors, and aids physical and visceral pain research.Formula:C32H39N3OColor and Shape:SolidMolecular weight:481.67Mibefradil dihydrochloride hydrate
CAS:Mibefradil dihydrochloride hydrate is a long-acting antihypertensive blocking high-voltage L calcium channels.Formula:C29H42Cl2FN3O4Color and Shape:SolidMolecular weight:586.57PDE1-IN-4
PDE1-IN-4: inhibits PDE1C/A/B with IC50s 10/145/354 nM, may help study idiopathic pulmonary fibrosis.Formula:C33H33N3O4Color and Shape:SolidMolecular weight:535.63TTA-P1
CAS:TTA-P1: potent T-type calcium channel inhibitor; impacts neuron firing, hormone secretion, cell growth; potential in absence epilepsy research.Formula:C19H27Cl2FN2OColor and Shape:SolidMolecular weight:389.33Verapamil EP Impurity C hydrochloride
CAS:NSC-609249 hydrochloride, an impurity of Verapamil, is a calcium channel blocker with potent orally active properties. It also functions as a first-generation P-glycoprotein (P-gp) inhibitor.Formula:C12H20ClNO2Color and Shape:SolidMolecular weight:245.75(Rac)-PD0299685
CAS:(Rac)-PD0299685 is a potent voltage-dependent calcium channel inhibitor for the study of retina-related diseases.
Formula:C10H21NO2Purity:97.20%Color and Shape:SolidMolecular weight:187.28Fostedil
CAS:Fostedil enhances heart function, maintains blood flow during partial/total coronary occlusions, and lowers aortic pressure.Formula:C18H20NO3PSPurity:98%Color and Shape:SolidMolecular weight:361.4
